Genomic Valley Biotech Valuation Multiples

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

Natera Inc is a diagnostic and research company with proprietary molecular and bioinformatics technology. The company's key product offerings include its Panorama Non-Invasive Prenatal Test (NIPT) which screens for chromosomal abnormalities of a fetus as well as in twin pregnancies, typically with a blood draw from the mother, Horizon Carrier Screening (HCS) to determine carrier status for a large number of severe genetic diseases that could be passed on to the carrier’s children, Signatera molecular residual disease (MRD) test, which detects circulating tumor DNA in patients previously diagnosed with cancer to assess molecular residual disease and monitor for recurrence; and Prospera, to assess organ transplant rejection.

BASF is one of the world’s leading chemical companies. It's headquartered in Germany near the Rhine River, which helps with logistics-related savings. Founded in 1865, it produces a vast array of chemicals, plastics, resins, and agricultural solutions. While the company serves multiple industries, it most prominently serves the automotive, agricultural, construction, and pharmaceutical industries. BASF is a first mover in the energy transition and aims to rapidly expand its recycled and bio-based product portfolio.

Archer-Daniels-Midland is a major processor of oilseeds, corn, wheat, and other agricultural commodities. The company is also one of the largest grain merchandisers through its extensive network of logistical assets to store and transport crops around the globe. ADM also runs a nutrition business that focuses on both human and animal ingredients and is a large producer of corn-based sweeteners, starches, and ethanol.

Muyuan Foods Group Co Ltd is engaged in pig farming and pig sales. Its business activities include livestock breeding, the production and trading of breeding livestock and poultry, the trading of live livestock and poultry for Hong Kong and Macao, feed production, livestock slaughtering, food production and sales, and animal treatment services.

Illumina is a genomics company headquartered in San Diego, California, that develops and sells DNA sequencing and array-based systems for research, clinical and applied markets. It was incorporated in April 1998 by David Walt, Larry Bock, John Stuelpnagel, Anthony Czarnik and Mark Chee, and its shares trade on the Nasdaq under the symbol ILMN. Its NovaSeq, NextSeq and MiSeq sequencers and microarrays are bought by genomic research centers, pharmaceutical companies, academic institutions and clinical laboratories. Revenue comes from instrument sales and from the consumables and services used with an installed base of about 21,000 systems in 165 countries. Fiscal 2025 revenue was $4.34 billion, flat on 2024, with GAAP net income of $850 million, and the company has about 8,600 employees. It acquired the cancer-detection company GRAIL in 2021 and completed its spin-off in June 2024, keeping a 14.5% minority stake. In January 2025 it invested $20 million in Truveta alongside Regeneron to support the Truveta Genome Project.

Created in 2018 as a result of the merger between PotashCorp and Agrium, Nutrien is the world’s largest fertilizer producer by capacity. Nutrien produces the three main crop nutrients—nitrogen, potash, and phosphate—although its main focus is potash, where it is the global leader in installed capacity with a roughly 20% market share. The company is also the largest agricultural retailer in North America and Australia, selling fertilizers, crop chemicals, seeds, and services directly to farm customers through its brick-and-mortar stores and online platforms.

Novonesis was formed in 2024 through the merger of Novozymes and Chr. Hansen. Following the merger, the company became the world leader in industrial enzymes and microbial solutions, with a nearly 50% market share in both. The firm supplies a wide range of industry groups: household care, food and beverages, bioenergy, agriculture and feed, technical and pharmaceuticals. Its biological solutions create value for its customers by improving yield efficiency and performance, while saving energy and generating less waste. The company is headquartered in Denmark, employs more than 11,000 people, and works across more than 30 research and development and application centers and 23 manufacturing sites.

Guardant Health, based in Redwood City, California, is a leader in liquid-based cancer tests for clinical and research use. The company's main franchises are Guardant360 for genomic profiling of tumors, Reveal for molecular residual disease testing, and Shield for colorectal cancer screening. Additionally, Guardant offers research development services such as regulatory approval consultancy and clinical trial referrals.

CF Industries is a leading producer and distributor of nitrogen, which is primarily used in fertilizers. The company operates nitrogen manufacturing plants primarily in North America. CF also produces nitrogen in the United Kingdom and holds a joint venture interest in a nitrogen production facility in Trinidad and Tobago. CF makes nitrogen primarily using low-cost US natural gas as its feedstock, making the company one of the lowest-cost nitrogen producers globally. It is also investing in carbon-free blue and green ammonia, which can be used as an alternative fuel to hydrogen or as a means to transport hydrogen.

Bunge Global SA is an agribusiness solutions company, connecting farmers to consumers and delivering essential food, feed and fuel to the globe. The company segments include Soybean Processing and Refining; Softseed Processing and Refining; Other Oilseeds Processing and Refining; Grain Merchandising and Milling; and Corporate and Other. It generates maximum revenue from the Soybean Processing and Refining segment, which includes integrated business principally involved in the purchase, storage, transportation, processing, distribution, refining, marketing, and sale of soybeans and soybean related products, as well as biodiesel and fertilizer production and distribution. Geographically, the company operates in United States, Switzerland, Netherlands, and Rest of the World.

Qinghai Salt Lake Industry Co Ltd operates in the dry inland Qarhan Salt Lake in Qinghai province. It is engaged in salt lake resource extraction and potash production. The company is engaged in the manufacture of chemical raw materials and chemical products. The company's main products include potassium chloride and lithium carbonate.

Industries Qatar QSC, along with its subsidiaries, operates in the following reportable segments: Petrochemicals, Fertilisers, and Steel. Maximum revenue is generated from the Fertilisers segment, which produces and sells urea, ammonia, and other by-products. The Petrochemicals segment produces and sells ethylene, polyethylene, MTBE, methanol, and other petrochemical products; and the Steel segment produces and sells steel pellets, bars, billets, and others.

Wens Foodstuff Group Co Ltd operates as a livestock and poultry farming company in China. The company offers fresh meat products and processed products, including chicken, pig, duck, milk, egg, cooked chicken, deep-sea fish, sheep, pigeons, and other products. It also provides raw milk and finished milk, such as pasteurized milk, fermented milk, sterilized milk, milk-containing beverages, and other various categories of products.

SABIC Agri-Nutrient Co is engaged in the production, conversion, manufacturing, and trade of agri-nutrients and chemical products. Also, the Company is engaged in the marketing of agri-nutrient products of all types inside and outside KSA. The Group is organised into two segments; The Agri-Nutrients and The Petrochemicals. The majority of revenue is derived from the Agri-Nutrients segment.

Wilmar International Ltd is a processor of palm and lauric oils and a producer of consumer pack edible oils. Its operating segment includes Food Products; Feed and Industrial Products; Plantation and Sugar Milling, Associates and Joint Ventures and others. The company generates maximum revenue from the Feed and Industrial Products segment. Its Feed and Industrial Products segment comprises the processing, merchandising, and distribution of products, which includes animal feeds, non-edible palm and lauric products, agricultural commodities, oleochemicals, gas oil, and biodiesel. Geographically, it derives a majority of revenue from the People's Republic of China.

Mowi ASA is a Norway-based producer of farmed salmon, distributing salmon and other processed seafood globally. The company focuses on producing high-quality fish by producing its fish eggs and nurturing the fish in the early stages of their life. It operates in three business segments: Feed, Farming, and Sales & Marketing. Fish feed production comprises its two feed plants in Norway and Scotland. Farming includes a single operating segment composed of farming operations in Norway, Scotland, Canada, Chile, Ireland, the Faroe Islands, and Iceland, and Sales and Marketing is composed of two operating segments: Markets and Consumer Products. A majority of the company's revenue is generated from the Sales and Marketing business. Geographically, it derives maximum revenue from Europe.

Yara International is an Oslo-headquartered global crop-nutrition and industrial-chemicals company. It manufactures and markets nitrogen fertilizers, ammonia, crop-nutrition products and selected industrial solutions through a worldwide production and distribution network. Its customers include farmers, agricultural retailers, industrial companies and distributors in global fertilizer markets. Revenue comes principally from sales of fertilizer, ammonia and related chemical products. The company traces its roots to Norsk Hydro’s 1905 fertilizer business and was separately listed as Yara in 2004. Yara acquired Saskferco in 2008 from Mosaic, Investment Saskatchewan and Citibank and now operates the Belle Plaine facility.

Twist Bioscience Corp is a synthetic biology company that has developed a disruptive DNA synthesis platform to industrialize the engineering of biology. The company’s proprietary semiconductor-based manufacturing process synthesizes DNA on silicon rather than traditional plastic plates, enabling the production of high-quality synthetic DNA faster, more affordably, and at scale. This platform overcomes conventional inefficiencies, supports cost-effective, high-throughput synthesis, and allows researchers to accelerate innovation. Geographically, the company operates across the Americas, EMEA, and APAC, deriving the majority of its revenue from the Americas.

SalMar ASA produces and sells farmed salmon internationally. It operates hatcheries and controls the farming at all stages until the fish are ready to be harvested, processed, and packaged into various products. Products are developed with new mixes and packing methods to make them more convenient for customers. The salmon are sold through an in-house salesforce and close partners of the company. Proximity to customers and tracking the use of resources play a factor in delivering the raw material.

10x Genomics Inc is a life science technology company based in the United States. Its solutions include instruments, consumables, and software for analyzing biological systems. The company's integrated solutions include instruments, consumables, and software for analyzing biological systems at a resolution and scale that matches the complexity of biology. Its product offerings include a Chromium platform comprising microfluidic chips and related consumables, Chromium X series, Visium and Xenium platforms, and others, which are predominantly used for the study of biological components. Geographically, the company derives operates from the United States and the rest from Americas (excluding the United States), Europe, Middle East and Africa, China, and Asia-Pacific (excluding China).

Corteva is an agricultural inputs pure play that was formed in 2019 when it was spun off from DowDuPont. The company is a leader in the development of new seed and crop protection products. Seeds generate the majority of profits with the remainder coming from crop protection products. Corteva plans to spin off its seeds business in late 2026 and will become a pure-play crop protection company following the divestiture. Corteva operates globally, but around half of revenue comes from North America.

Tongwei is the world's largest polysilicon producer and a leading solar cell and module supplier. The solar business contributed more than 60% of revenue in 2024. In addition, Tongwei runs a feed and food business, which made up 35% of revenue in 2024.

The Mosaic Company is a US-listed producer of concentrated phosphate and potash crop nutrients. It mines and processes mineral resources and supplies fertiliser products to agricultural customers and distributors across global markets. Revenue comes from the sale of commodity and value-added crop-nutrition products, supported by mining, processing and logistics assets. The company was created in 2004 and operates major assets in the United States and Canada, making it a direct operating exposure to agricultural inputs and resources. The Mosaic Company serves B2B customers through activities spanning Chemicals, Agriculture and Metals & Mining. Its commercial model generates revenue through Product sales and Wholesale Distribution, supported by sector expertise, operating execution and customer relationships.

GRAIL Inc is a healthcare company focused on developing technologies for early cancer detection. The company has developed a multi-cancer early detection blood test that has the ability to detect all types of cancer, across all stages. It operates in one reportable operating segment which provides multi-cancer early detection testing and service.

Fertilizer and crop protection company, part of the Murugappa group. It makes phosphatic and complex fertilizers, specialty nutrients and agrochemicals, and runs rural retail outlets serving farmers. Headquartered in Secunderabad (Hyderabad).

BillionToOne Inc is a precision diagnostics company revolutionizing molecular testing with its patented Quantitative Counting Templates (QCT) platform. This technology enables ultrasensitive, single-molecule DNA quantification, making genetic testing more accurate, affordable, and accessible. The company serves prenatal screening and oncology markets with non-invasive tests that detect fetal genetic risks and monitor cancer therapy response.

Fertiglobe PLC is engaged in the production of urea, ammonia, and other gas-based fertilizers for export and distribution. The company's portfolio of products comprises ammonia, urea for agricultural and industrial customers, and DEF, which is also known as AdBlue in Europe and marketed as AdGreen by FERTIL, for industrial customers. The company operates in Europe, North America, South America, Africa, Middle East, Asia and Oceania. Majority of revenue is from Europe.

State-owned fertilizer and chemicals maker in Kerala. It produces complex fertilizers such as Factamfos, ammonium sulphate and caprolactam, selling mainly to farmers through dealers. Headquartered in Udyogamandal, Kochi.

Beijing Wantai Biological Pharmacy Enterprise Co Ltd is engaged in research, development, production, and sales of in vitro diagnostic reagents, instruments, and vaccines. The company has two segments: Diagnostic and Vaccine. The Diagnostic segment develops and sells in vitro diagnostic reagents such as ELISA, colloidal gold, biochemical, and chemiluminescent kits, along with instruments including chemiluminescent analyzers, fluorescent analyzers, and nucleic acid purification systems. The Vaccine segment focuses on products like the hepatitis E vaccine, the bivalent HPV vaccine, and the nasal spray COVID-19 vaccine. It generates the majority of its revenue from the Diagnostic segment.

UPL Ltd is principally engaged in the business of manufacturing and sale of crop protection products. The firm's crop protection portfolio includes fungicides, herbicides, insecticides, plant growth regulators, rodenticides, and specialty crop chemicals. The firm's seed products consist of nutri-feeds, seeds, and seed treatment products. UPL competes on price with the manufacture and sale of generic products. The company generates its revenue globally, with sales in various countries, and derives a majority share of its revenue from its business outside India. The firm sells its products through a distribution network in each region.

Vinamilk is Vietnam's leading dairy producer and a major listed consumer-products company. Founded in 1976 and headquartered in Ho Chi Minh City, it manufactures liquid milk, powdered milk, yoghurt, condensed milk, beverages, ice cream and nutritional products. The group operates dairy farms, production plants and a nationwide distribution network while exporting to dozens of markets. Revenue is generated from branded product sales to retailers, distributors, institutions and consumers. Vinamilk held an estimated 58% share of Vietnam's liquid-milk market around the 2017 strategic investment. SCIC remained its largest state shareholder while selling minority blocks to international investors. The two retained SCIC sales are secondary strategic placements in the same operating company and must use one existing Vinamilk identity.

CareDx Inc operates as a precision medicine company focused on the discovery, development, and commercialization of clinically differentiated, high-value healthcare solutions for transplant patients and caregivers. It offers testing services, products, and digital solutions along with the pre- and post-transplant patient journey and is a provider of genomics-based information for transplant patients. The Company's commercially available testing services consist of AlloSure Kidney, AlloMap Heart, AlloSure Heart, a dd-cfDNA solution for heart transplant patients, and AlloSure Lung, a dd-cfDNA solution for lung transplant patients. Geographically it generates the majority of its revenue from the United States. The company generates the majority of revenue from the Testing services.

Veracyte Inc is a genomic diagnostics company. The group empowers clinicians with the insights necessary to guide and assure patients at pivotal moments in the race to diagnose and treat cancer. It offers tests for prostate cancer (Decipher Prostate), thyroid cancer (Afirma), breast cancer (Prosigna), and bladder cancer (Decipher Bladder). In addition, its Percepta Nasal Swab test is being run in CLIA labs in support of clinical studies.

Scotts Miracle-Gro is the largest purveyor of home lawn and gardening products in the US. The company sells a broad range of lawncare products, including grass seed, fertilizer, and lawn-related weed, animal, and disease control. US consumer typically generates the vast majority of companywide revenue and profits. Its lawncare and gardening products are well-recognized brands in the US, including Scotts, Miracle-Gro, Roundup, Ortho, and Tomcat.

Oman India Fertiliser Co SAOG is a joint venture between Oman and India, focused on the production of ammonia and urea. The Company operates a two-train ammonia and a two-train urea fertiliser manufacturing facility in Oman, with a nameplate production capacity of approximately 1.15 million metric tonnes of ammonia per annum and around 1.65 million metric tonnes of urea per annum. mIt combines Oman's energy advantage - leveraging abundant natural gas as its primary feedstock - with India's agricultural demand as its key offtake market, creating a platform for growth in other markets.

PI Industries Ltd manufactures, distributes, and sells agrochemicals, specialty fertilizers, and seeds to the agriculture industry. The firm's agrochemicals portfolio includes insecticides, fungicides, and plant health products. The company competes on price with the manufacture and sale of generic products. PI Industries reports sales across two geographical segments: within India and outside India. The outside India division represents its business division predominantly in Japan, Germany, and China. In India, the firm sells its products through a large network of distributors and retail outlets. The company has one reportable business segment which is Agro Chemicals.

Celcuity Inc is a clinical-stage biotechnology company developing targeted therapies for multiple solid tumors. Its candidate, gedatolisib, is a kinase inhibitor of the PI3K/AKT/mTOR (PAM) pathway, binding all class I PI3K isoforms and mTORC1/2, offering comprehensive inhibition with a mechanism and pharmacokinetics differentiated from other therapies. The Phase 3 VIKTORIA-1 trial, evaluating gedatolisib with fulvestrant, with or without palbociclib, in HR+/HER2- breast cancer, has completed enrollment and reported results for PIK3CA WT tumors, with cohort 2 (PIK3CA MT) also enrolled. Phase 3 VIKTORIA-2 and Phase 1b/2 CELC-G-201 trials, evaluating combinations in endocrine-resistant HR+/HER2- breast cancer and metastatic castration-resistant prostate cancer, are ongoing.

Bakkafrost P/F is a salmon producer based in the Faroe Islands. The company's activities include farming, harvesting, packaging, processing, and sales. The salmon products consist of whole salmon, frozen salmon portions, salmon heads, backbones, belly flaps, and salmon skin. Bakkafrost divides its operations into segments namely, Fishmeal, oil and feed segment, Freshwater FO segment, Farming FO segment, Freshwater SCT segment, Farming SCT segment, services, sales, and others. Geographically, the company derives maximum revenue from Western Europe.

Golden Agri-Resources Ltd is an integrated palm oil plantation company. It operates through two segments namely Plantations and palm oil mills, and Palm, laurics, and others. The plantation and palm oil mills segment comprises the products from the upstream business. The Palm, laurics and others comprise the processing and merchandising of palm and oilseed-based products i.e. bulk, branded, oleo-chemicals and other vegetable oils. The majority of the revenue is generated from the Palm, laurics and other segments. Geographically, the company operates in China, Indonesia, India, Rest of Asia, Europe and Others.

K+S AG produces two products: fertilizer and salt. The company engaged in business with potash and magnesium products from plants in Germany and Canadian sites in Bethune, as well as the European salt activities. It also includes the waste disposal and recycling business in Germany. extraction and processing of raw materials.

Olam Group Ltd is a food and agri-business supplying customers with food ingredients, feed, and fibre. The company and its subsidiaries operate in the following business segments: Olam Food Ingredients, Olam Global Agri, and the Remaining Olam Group. It generates maximum revenue from the Olam Global Agri segment, which is engaged in the origination, processing, trading, logistics, and distribution of grains, animal feed and protein, edible oil, rice, cotton, rubber, and wood products. It also provides commodity financial services. Geographically, the company derives majority of its revenue from Asia, the Middle East, and Australia, and the rest from Africa, Europe, and the Americas.

KWS SAAT SE & Co KGaA breeds and distributes agriculture seeds internationally. The segments of the company focus on sugarbeet, corn, cereals, vegetables, and corporates. The company works on breeding new varieties and seed multiplication to produce the results for farmers. Plants and seeds are monitored at different stages of the lifecycle to ensure high quality. Products, processes, and consulting are marketed to farmers as certain expertise is needed in different regions of the world. The company generates key revenue from Sugarbeet and Corn.

BGI Genomics Co Ltd is a China-based company principally engaged in the provision of genomic class diagnosis and research services through the application of biotechnology. It offers its services in various research areas, such as agriculture and food science, cancer research, metagenomics, reproductive health, biomarker discovery, and drug discovery. The company mainly provides services for domestic and overseas academic institutions hospitals, medical institutions and others.

Hatsun Agro Product processes milk and sells dairy products such as milk, curd, ice cream and ghee under brands including Arun, Arun Icecreams and Ibaco. It buys milk from farmers in southern India and sells through retail distribution and its own parlours. It is one of India's largest private dairy companies. Headquartered in Chennai.

BF is an Italian holding company active across the agro-industrial supply chain, from farming to food products. It was founded in Milan on 30 May 2014 as B.F. Holding and has its registered office in Jolanda di Savoia in the province of Ferrara. The group grew around Bonifiche Ferraresi, an agricultural company that farms 7,750 hectares and is the largest Italian farm by utilised agricultural area. Its other businesses include seeds, pasta, couscous and organic food, and it invests in agricultural consortia and food companies. B.F. S.p.A. has been listed on Borsa Italiana since 23 June 2017, where it trades under the ticker BFG and sits in the FTSE Italia Mid Cap index. Federico Vecchioni is executive chairman and Rossella Locatelli is chair of the board. The group describes its approach as controlling the production chain from the genome to the shelf.

Andersons Inc is an agriculture and renewable fuels company. Its operations are classified into two reportable business segments: Agribusiness, which generates maximum revenue, and Renewables. The Agribusiness segment includes merchandising and managing logistics across various commodities, as well as being a manufacturer, distributor, and retailer of agricultural and related plant nutrients. The segment specializes in the movement of physical commodities such as whole grains, grain products, feed ingredients, and domestic fuel products, among other agricultural commodities. The Renewables segment mainly produces, purchases, and sells ethanol and co-products. Geographically, the company generates maximum revenue from the United States, followed by Canada, Mexico, and other markets.

Genus PLC is an animal genetics company focused on improving cattle and pig populations to support sustainable food production. The company operates through two main business units: one providing bovine genetics mainly for dairy and beef cattle, and the other offering porcine genetics for pork production. Genus develops genetically superior breeding animals using scientific techniques. It generates revenue by selling genetics, including semen and embryos, as well as through related services under multi-year royalty agreements. The principal activities of each segment are: (a) Genus PIC porcine sales business, (b) Genus ABS: bovine sales business, and (c) Genus Research and Development: spending on research and development.