BillionToOne Inc is a precision diagnostics company revolutionizing molecular testing with its patented Quantitative Counting Templates (QCT) platform. This technology enables ultrasensitive, single-molecule DNA quantification, making genetic testing more accurate, affordable, and accessible. The company serves prenatal screening and oncology markets with non-invasive tests that detect fetal genetic risks and monitor cancer therapy response.
2016
n/a
LTM Revenue $296M
LTM EBITDA $23.0M
$4.0B
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As of January 2026, BillionToOne reported last 12-month revenue of $296M and EBITDA of $23.0M.
In the same period, BillionToOne generated $198M in LTM gross profit and $2.2M in net income.
See BillionToOne valuation multiples based on analyst estimatesIn the most recent fiscal year, BillionToOne reported revenue of $153M and EBITDA of -$27.5M.
BillionToOne expects next 12-month revenue of XXX   and NTM EBITDA of XXX
See BillionToOne valuation multiples based on analyst estimates| LTM | NTM | Last FY | FY 2026 | FY 2027 | FY 2028 | |
|---|---|---|---|---|---|---|
| Revenue | $296M | XXX | $153M | XXX | XXX | XXX |
| Gross Profit | $198M | XXX | $80.9M | XXX | XXX | XXX |
| Gross Margin | 67% | XXX | 53% | XXX | XXX | XXX |
| EBITDA | $23.0M | XXX | -$27.5M | XXX | XXX | XXX |
| EBITDA Margin | 8% | XXX | -18% | XXX | XXX | XXX |
| EBIT | $8.2M | XXX | -$47.1M | XXX | XXX | XXX |
| EBIT Margin | 3% | XXX | -31% | XXX | XXX | XXX |
| Net Profit | $2.2M | XXX | -$41.6M | XXX | XXX | XXX |
| Net Margin | 1% | XXX | -27% | XXX | XXX | XXX |
| Net Debt | XXX | XXX | n/a | XXX | XXX | XXX |
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BillionToOne has current market cap of $4.1B, and EV of $4.0B.
As of February 20, 2026, BillionToOne's stock price is $89.
See BillionToOne trading valuation data| EV | Market Cap | Price 1D | Price 1M | Price 3M | Price 12M | EPS |
|---|---|---|---|---|---|---|
| $4.0B | $4.1B | XXX | XXX | XXX | XXX | $0.10 |
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Start Free TrialBillionToOne's trades at 13.5x EV/Revenue multiple, and 173.3x EV/EBITDA.
See valuation multiples for BillionToOne and 15K+ public compsAs of February 20, 2026, BillionToOne has market cap of $4.1B and EV of $4.0B.
Equity research analysts estimate BillionToOne's 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX
BillionToOne has a P/E ratio of 1884.9x.
| LTM | NTM | Last FY | FY 2026 | FY 2027 | FY 2028 | |
|---|---|---|---|---|---|---|
| Market cap (current) | $4.1B | XXX | $4.1B | XXX | XXX | XXX |
| EV (current) | $4.0B | XXX | $4.0B | XXX | XXX | XXX |
| EV/Revenue | 13.5x | XXX | 13.5x | XXX | XXX | XXX |
| EV/EBITDA | 173.3x | XXX | 173.3x | XXX | XXX | XXX |
| EV/EBIT | 485.5x | XXX | 485.5x | XXX | XXX | XXX |
| EV/Gross Profit | 20.1x | XXX | n/a | XXX | XXX | XXX |
| P/E | 1884.9x | XXX | -98.1x | XXX | XXX | XXX |
| EV/FCF | 9979.7x | XXX | 9979.7x | XXX | XXX | XXX |
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Start Free TrialBillionToOne's last 12 month revenue growth is 36%
BillionToOne's revenue per employee in the last FY averaged n/a, while opex per employee averaged n/a for the same period.
BillionToOne's rule of 40 is -66% (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).
BillionToOne's rule of X is 97% (created by Bessemer, rule of X is another metric relevant for SaaS companies only, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).
See operational valuation multiples for BillionToOne and other 15K+ public comps| LTM | NTM | Last FY | FY 2026 | FY 2027 | FY 2028 | |
|---|---|---|---|---|---|---|
| Revenue Growth | 36% | XXX | 35% | XXX | XXX | XXX |
| EBITDA Margin | 8% | XXX | 8% | XXX | XXX | XXX |
| EBITDA Growth | 31% | XXX | n/a | XXX | XXX | XXX |
| Rule of 40 | -66% | XXX | 44% | XXX | XXX | XXX |
| Bessemer Rule of X | XXX | XXX | 97% | XXX | XXX | XXX |
| Revenue per Employee | XXX | XXX | n/a | XXX | XXX | XXX |
| Opex per Employee | XXX | XXX | n/a | XXX | XXX | XXX |
| S&M Expenses to Revenue | XXX | XXX | n/a | XXX | XXX | XXX |
| G&A Expenses to Revenue | XXX | XXX | n/a | XXX | XXX | XXX |
| R&D Expenses to Revenue | XXX | XXX | 24% | XXX | XXX | XXX |
| Opex to Revenue | XXX | XXX | 84% | XXX | XXX | XXX |
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| EV/Revenue | EV/EBITDA | |||||
|---|---|---|---|---|---|---|
| 2025E | 2026E | 2027E | 2025E | 2026E | 2027E | |
| EZZ Life Science | XXX | XXX | XXX | XXX | XXX | XXX |
| Epigenomics | XXX | XXX | XXX | XXX | XXX | XXX |
| Mirxes Holding Co | XXX | XXX | XXX | XXX | XXX | XXX |
| ToolGen | XXX | XXX | XXX | XXX | XXX | XXX |
| 4basebio | XXX | XXX | XXX | XXX | XXX | XXX |
| XXXXXXXX | XXX | XXX | XXX | XXX | XXX | XXX |
| XXXXXXXX | XXX | XXX | XXX | XXX | XXX | XXX |
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BillionToOne acquired XXX companies to date.
Last acquisition by BillionToOne was XXXXXXXX, XXXXX XXXXX XXXXXX . BillionToOne acquired XXXXXXXX for XXX (EV/Revenue multiple of XXX ).
See M&A valuation multiples| Acquired Company | EV | EV/Revenue | EV/EBITDA |
|---|---|---|---|
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
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Start Free Trial| When was BillionToOne founded? | BillionToOne was founded in 2016. |
| Where is BillionToOne headquartered? | BillionToOne is headquartered in United States of America. |
| Who is the CEO of BillionToOne? | BillionToOne's CEO is Dr. Oguzhan Atay, PhD. |
| Is BillionToOne publicy listed? | Yes, BillionToOne is a public company listed on NAS. |
| What is the stock symbol of BillionToOne? | BillionToOne trades under BLLN ticker. |
| When did BillionToOne go public? | BillionToOne went public in 2025. |
| Who are competitors of BillionToOne? | Similar companies to BillionToOne include e.g. EZZ Life Science, Epigenomics, Mirxes Holding Co, ToolGen. |
| What is the current market cap of BillionToOne? | BillionToOne's current market cap is $4.1B |
| What is the current revenue of BillionToOne? | BillionToOne's last 12 months revenue is $296M. |
| What is the current revenue growth of BillionToOne? | BillionToOne revenue growth (NTM/LTM) is 36%. |
| What is the current EV/Revenue multiple of BillionToOne? | Current revenue multiple of BillionToOne is 13.5x. |
| Is BillionToOne profitable? | Yes, BillionToOne is EBITDA-positive (as of the last 12 months). |
| What is the current EBITDA of BillionToOne? | BillionToOne's last 12 months EBITDA is $23.0M. |
| What is BillionToOne's EBITDA margin? | BillionToOne's last 12 months EBITDA margin is 8%. |
| What is the current EV/EBITDA multiple of BillionToOne? | Current EBITDA multiple of BillionToOne is 173.3x. |
| What is the current FCF of BillionToOne? | BillionToOne's last 12 months FCF is $0.4M. |
| What is BillionToOne's FCF margin? | BillionToOne's last 12 months FCF margin is 0%. |
| What is the current EV/FCF multiple of BillionToOne? | Current FCF multiple of BillionToOne is 9979.7x. |
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