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BillionToOne Valuation Multiples

Discover revenue and EBITDA valuation multiples for BillionToOne and similar public comparables like Epigenomics, ToolGen, and 4basebio.

BillionToOne Overview

About BillionToOne

BillionToOne Inc is a precision diagnostics company revolutionizing molecular testing with its patented Quantitative Counting Templates (QCT) platform. This technology enables ultrasensitive, single-molecule DNA quantification, making genetic testing more accurate, affordable, and accessible. The company serves prenatal screening and oncology markets with non-invasive tests that detect fetal genetic risks and monitor cancer therapy response.


Founded

2016

HQ

United States of America
Employees

n/a

Financials

Last FY Revenue $153M

Last FY EBITDA -$27.5M

EV

$4.1B

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BillionToOne Financials

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BillionToOne P&L

In the most recent fiscal year, BillionToOne reported revenue of $153M and EBITDA of -$27.5M.

BillionToOne expects next 12-month revenue of  XXX    and NTM EBITDA of  XXX

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NTM Last FY FY 2025 FY 2026 FY 2027
Revenue XXX $153M XXX XXX XXX
Gross Profit XXX $80.9M XXX XXX XXX
Gross Margin XXX 53% XXX XXX XXX
EBITDA XXX -$27.5M XXX XXX XXX
EBITDA Margin XXX -18% XXX XXX XXX
EBIT XXX -$47.1M XXX XXX XXX
EBIT Margin XXX -31% XXX XXX XXX
Net Profit XXX -$41.6M XXX XXX XXX
Net Margin XXX -27% XXX XXX XXX
Net Debt XXX n/a XXX XXX XXX

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BillionToOne Stock Performance

BillionToOne has current market cap of $4.2B, and EV of $4.1B.

Market Cap Evolution

BillionToOne Stock Data

As of December 17, 2025, BillionToOne's stock price is $92.

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EV Market Cap Price 1D Price 1M Price 3M Price 12M EPS
$4.1B $4.2B XXX XXX XXX XXX n/a

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BillionToOne Valuation Multiples

BillionToOne's trades at 27.0x EV/Revenue multiple, and -150.1x EV/EBITDA.

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BillionToOne Financial Valuation Multiples

As of December 17, 2025, BillionToOne has market cap of $4.2B and EV of $4.1B.

Equity research analysts estimate BillionToOne's 2025E EV/Revenue multiple at  XXX and 2025E EV/EBITDA multiple at  XXX

BillionToOne's P/E ratio is not available.

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Market cap (current) $4.2B XXX $4.2B XXX XXX XXX
EV (current) $4.1B XXX $4.1B XXX XXX XXX
EV/Revenue n/a XXX 27.0x XXX XXX XXX
EV/EBITDA n/a XXX -150.1x XXX XXX XXX
EV/EBIT n/a XXX -87.4x XXX XXX XXX
EV/Gross Profit n/a XXX n/a XXX XXX XXX
P/E n/a XXX -101.2x XXX XXX XXX
EV/FCF n/a XXX -88.1x XXX XXX XXX

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BillionToOne Margins & Growth Rates

BillionToOne's revenue per employee in the last FY averaged n/a, while opex per employee averaged n/a for the same period.

BillionToOne's rule of 40 is unknown (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

BillionToOne's rule of X is unknown (created by Bessemer, rule of X is another metric relevant for SaaS companies only, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

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BillionToOne Operational Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue Growth n/a XXX 62% XXX XXX XXX
EBITDA Margin n/a XXX -18% XXX XXX XXX
EBITDA Growth n/a XXX n/a XXX XXX XXX
Rule of 40 n/a XXX n/a XXX XXX XXX
Bessemer Rule of X XXX XXX n/a XXX XXX XXX
Revenue per Employee XXX XXX n/a XXX XXX XXX
Opex per Employee XXX XXX n/a XXX XXX XXX
S&M Expenses to Revenue XXX XXX n/a XXX XXX XXX
G&A Expenses to Revenue XXX XXX n/a XXX XXX XXX
R&D Expenses to Revenue XXX XXX 24% XXX XXX XXX
Opex to Revenue XXX XXX 84% XXX XXX XXX

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BillionToOne Public Comps

See public comps and valuation multiples for Genomics & Personalized Medicine comps
EV/Revenue EV/EBITDA
2025E 2026E 2027E 2025E 2026E 2027E
EZZ Life Science XXX XXX XXX XXX XXX XXX
Epigenomics XXX XXX XXX XXX XXX XXX
Mirxes Holding Co XXX XXX XXX XXX XXX XXX
ToolGen XXX XXX XXX XXX XXX XXX
4basebio XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX

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BillionToOne M&A and Investment Activity

BillionToOne acquired  XXX companies to date.

Last acquisition by BillionToOne was  XXXXXXXX, XXXXX XXXXX XXXXXX . BillionToOne acquired  XXXXXXXX for  XXX (EV/Revenue multiple of  XXX ).

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Latest Acquisitions by BillionToOne

Acquired Company EV EV/Revenue EV/EBITDA
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX

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About BillionToOne

When was BillionToOne founded? BillionToOne was founded in 2016.
Where is BillionToOne headquartered? BillionToOne is headquartered in United States of America.
Who is the CEO of BillionToOne? BillionToOne's CEO is Dr. Oguzhan Atay, PhD.
Is BillionToOne publicy listed? Yes, BillionToOne is a public company listed on NAS.
What is the stock symbol of BillionToOne? BillionToOne trades under BLLN ticker.
When did BillionToOne go public? BillionToOne went public in 2025.
Who are competitors of BillionToOne? Similar companies to BillionToOne include e.g. EZZ Life Science, Epigenomics, Mirxes Holding Co, ToolGen.
What is the current market cap of BillionToOne? BillionToOne's current market cap is $4.2B
Is BillionToOne profitable? Yes, BillionToOne is EBITDA-positive (as of the last 12 months).

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