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Illumina Valuation Multiples

Discover revenue and EBITDA valuation multiples for Illumina and similar public comparables like Genus, Epigenomics, and EZZ Life Science.

Illumina Overview

About Illumina

Illumina provides tools and services to analyze genetic material with life science and clinical lab applications. The company generates over 90% of its revenue from sequencing instruments, consumables, and services. Illumina’s high-throughput technology enables whole genome sequencing in humans and other large organisms. Its lower throughput tools enable applications that require smaller data outputs, such as viral and cancer tumor screening. Illumina also sells microarrays (9% of 2024 sales) that enable lower-cost, focused genetic screening with primarily consumer and agricultural applications.


Founded

1998

HQ

United States of America
Employees

10.4K+

Website

illumina.com

Financials

LTM Revenue $4.3B

LTM EBITDA $1.2B

EV

$14.4B

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Illumina Financials

Illumina has a last 12-month revenue (LTM) of $4.3B and a last 12-month EBITDA of $1.2B.

In the most recent fiscal year, Illumina achieved revenue of $4.4B and an EBITDA of -$725M.

Illumina expects next 12-month revenue of  XXX    and NTM EBITDA of  XXX

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Illumina P&L

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue $4.3B XXX $4.4B XXX XXX XXX
Gross Profit $2.9B XXX $2.9B XXX XXX XXX
Gross Margin 68% XXX 65% XXX XXX XXX
EBITDA $1.2B XXX -$725M XXX XXX XXX
EBITDA Margin 27% XXX -17% XXX XXX XXX
EBIT $920M XXX $600M XXX XXX XXX
EBIT Margin 21% XXX 14% XXX XXX XXX
Net Profit $505M XXX -$1.2B XXX XXX XXX
Net Margin 12% XXX -28% XXX XXX XXX
Net Debt XXX XXX $862M XXX XXX XXX

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Illumina Stock Performance

As of May 30, 2025, Illumina's stock price is $82.

Illumina has current market cap of $13.0B, and EV of $14.4B.

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Illumina Stock Data

EV Market Cap Price 1D Price 1M Price 3M Price 12M EPS
$14.4B $13.0B XXX XXX XXX XXX $4.19

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Illumina Valuation Multiples

As of May 30, 2025, Illumina has market cap of $13.0B and EV of $14.4B.

Illumina's trades at 3.3x EV/Revenue multiple, and -19.8x EV/EBITDA.

Equity research analysts estimate Illumina's 2025E EV/Revenue multiple at  XXX and 2025E EV/EBITDA multiple at  XXX

Illumina has a P/E ratio of 25.8x.

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Illumina Financial Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Market cap (current) $13.0B XXX $13.0B XXX XXX XXX
EV (current) $14.4B XXX $14.4B XXX XXX XXX
EV/Revenue 3.3x XXX 3.3x XXX XXX XXX
EV/EBITDA 12.5x XXX -19.8x XXX XXX XXX
EV/EBIT 15.6x XXX 24.0x XXX XXX XXX
EV/Gross Profit 4.9x XXX n/a XXX XXX XXX
P/E 25.8x XXX -10.6x XXX XXX XXX
EV/FCF 16.9x XXX 20.3x XXX XXX XXX

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Illumina Margins & Growth Rates

Illumina's last 12 month revenue growth is -1%

Illumina's revenue per employee in the last FY averaged $0.4M, while opex per employee averaged $0.2M for the same period.

Illumina's rule of 40 is -14% (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Illumina's rule of X is 25% (created by Bessemer, rule of X is another metric relevant for SaaS companies only, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

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Illumina Operational Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue Growth -1% XXX 0% XXX XXX XXX
EBITDA Margin 27% XXX -17% XXX XXX XXX
EBITDA Growth 1% XXX n/a XXX XXX XXX
Rule of 40 -14% XXX -17% XXX XXX XXX
Bessemer Rule of X XXX XXX 25% XXX XXX XXX
Revenue per Employee XXX XXX $0.4M XXX XXX XXX
Opex per Employee XXX XXX $0.2M XXX XXX XXX
S&M Expenses to Revenue XXX XXX n/a XXX XXX XXX
G&A Expenses to Revenue XXX XXX n/a XXX XXX XXX
R&D Expenses to Revenue XXX XXX 27% XXX XXX XXX
Opex to Revenue XXX XXX 52% XXX XXX XXX

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Illumina Public Comps

See public comps and valuation multiples for Genomics & Personalized Medicine and Laboratory Services comps
EV/Revenue EV/EBITDA
2025E 2026E 2027E 2025E 2026E 2027E
EZZ Life Science XXX XXX XXX XXX XXX XXX
Epigenomics XXX XXX XXX XXX XXX XXX
ToolGen XXX XXX XXX XXX XXX XXX
4basebio XXX XXX XXX XXX XXX XXX
Genus XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX

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Illumina M&A and Investment Activity

Illumina acquired  XXX companies to date.

Last acquisition by Illumina was  XXXXXXXX, XXXXX XXXXX XXXXXX . Illumina acquired  XXXXXXXX for  XXX (EV/Revenue multiple of  XXX ).

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Latest Acquisitions by Illumina

Acquired Company EV EV/Revenue EV/EBITDA
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX

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About Illumina

When was Illumina founded? Illumina was founded in 1998.
Where is Illumina headquartered? Illumina is headquartered in United States of America.
How many employees does Illumina have? As of today, Illumina has 10.4K+ employees.
Who is the CEO of Illumina? Illumina's CEO is Mr. Jacob Thaysen.
Is Illumina publicy listed? Yes, Illumina is a public company listed on NAS.
What is the stock symbol of Illumina? Illumina trades under ILMN ticker.
When did Illumina go public? Illumina went public in 2000.
Who are competitors of Illumina? Similar companies to Illumina include e.g. EZZ Life Science, Epigenomics, ToolGen, 4basebio.
What is the current market cap of Illumina? Illumina's current market cap is $13.0B
What is the current revenue of Illumina? Illumina's last 12 months revenue is $4.3B.
What is the current revenue growth of Illumina? Illumina revenue growth (NTM/LTM) is -1%.
What is the current EV/Revenue multiple of Illumina? Current revenue multiple of Illumina is 3.3x.
Is Illumina profitable? Yes, Illumina is EBITDA-positive (as of the last 12 months).
What is the current EBITDA of Illumina? Illumina's last 12 months EBITDA is $1.2B.
What is Illumina's EBITDA margin? Illumina's last 12 months EBITDA margin is 27%.
What is the current EV/EBITDA multiple of Illumina? Current EBITDA multiple of Illumina is 12.5x.
What is the current FCF of Illumina? Illumina's last 12 months FCF is $850M.
What is Illumina's FCF margin? Illumina's last 12 months FCF margin is 20%.
What is the current EV/FCF multiple of Illumina? Current FCF multiple of Illumina is 16.9x.

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