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Illumina Valuation Multiples

Discover revenue and EBITDA valuation multiples for Illumina and similar public comparables like Sartorius, Exact Sciences, Steris, Zimmer Biomet and more.

Illumina Overview

About Illumina

Illumina provides tools and services to analyze genetic material with life science and clinical lab applications. The company generates over 90% of its revenue from sequencing instruments, consumables, and services. Illumina’s high-throughput technology enables whole genome sequencing in humans and other large organisms. Its lower throughput tools enable applications that require smaller data outputs, such as viral and cancer tumor screening. Illumina also sells microarrays (9% of 2024 sales) that enable lower-cost, focused genetic screening with primarily consumer and agricultural applications.


Founded

1998

HQ

United States

Employees

10.1K

Financials (LTM)

Revenue: $4B
EBITDA: $1B

EV

$21B

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Illumina Financials

Illumina reported last 12-month revenue of $4B and EBITDA of $1B.

In the same LTM period, Illumina generated $3B in gross profit, $1B in EBITDA, and $767M in net income.

Revenue (LTM)


Illumina P&L

In the most recent fiscal year, Illumina reported revenue of $4B and EBITDA of $1B.

Illumina expects next 12-month revenue of XXX and NTM EBITDA of XXX

See Illumina forward-looking valuation multiples
LTMNTMLast FYFY 2026FY 2027FY 2028
Revenue$4BXXX$4BXXXXXXXXX
Gross Profit$3BXXX$3BXXXXXXXXX
Gross Margin68%XXX66%XXXXXXXXX
EBITDA$1BXXX$1BXXXXXXXXX
EBITDA Margin28%XXX34%XXXXXXXXX
EBIT Margin23%XXX23%XXXXXXXXX
Net Profit$767MXXX$850MXXXXXXXXX
Net Margin17%XXX20%XXXXXXXXX
Net Debtβ€”β€”$571MXXXXXXXXX

Financial data powered by Morningstar, Inc.

Illumina Stock Performance

Illumina has current market cap of $20B, and enterprise value of $21B.

Market Cap Evolution


Illumina's stock price is $134.50.

See Illumina trading valuation data
EVMarket CapPrice 1DPrice 1MPrice 3MPrice 12MEPS
$21B$20B1.3%XXXXXXXXX$5.60

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Illumina Valuation Multiples

Illumina trades at 4.9x EV/Revenue multiple, and 17.2x EV/EBITDA.

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EV / Revenue (LTM)


Illumina Financial Valuation Multiples

As of April 18, 2026, Illumina has market cap of $20B and EV of $21B.

Equity research analysts estimate Illumina's 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX

Illumina has a P/E ratio of 26.6x.

LTMNTMLast FYFY 2026FY 2027FY 2028
Market cap (current)$20BXXX$20BXXXXXXXXX
EV (current)$21BXXX$21BXXXXXXXXX
EV/Revenue4.9xXXX4.9xXXXXXXXXX
EV/EBITDA17.2xXXX14.7xXXXXXXXXX
EV/EBIT20.9xXXX21.3xXXXXXXXXX
EV/Gross Profit7.1xXXX7.4xXXXXXXXXX
P/E26.6xXXX24.0xXXXXXXXXX
EV/FCF24.1xXXX22.3xXXXXXXXXX

Valuation data powered by FactSet, Inc. and Morningstar, Inc.

Verified Illumina Valuation Multiples

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Illumina Margins & Growth Rates

Illumina's revenue in the last 12 month grew by 5%.

Illumina's revenue per employee in the last FY averaged $0.4M, while opex per employee averaged $0.2M for the same period.

Illumina's rule of 40 is 33% (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Illumina's rule of X is 39% (created by Bessemer, rule of X is another metric to measure SaaS companies, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

See operational valuation multiples for Illumina and other 15K+ public comps

Illumina Operational Valuation Multiples

LTMNTMLast FYFY 2026FY 2027FY 2028
Revenue Growth5%XXX4%XXXXXXXXX
EBITDA Margin28%XXX34%XXXXXXXXX
EBITDA Growth7%XXX(12%)XXXXXXXXX
Rule of 40β€”XXX33%XXXXXXXXX
Bessemer Rule of Xβ€”XXX39%XXXXXXXXX
Revenue per Employeeβ€”XXX$0.4MXXXXXXXXX
Opex per Employeeβ€”XXX$0.2MXXXXXXXXX
R&D Expenses to Revenue22%XXX22%XXXXXXXXX
Opex to Revenueβ€”XXX47%XXXXXXXXX

Valuation data powered by FactSet, Inc. and Morningstar, Inc.

Valuation Multiples Across 230+ Verticals

Illumina Public Comps

See public comps and valuation multiples for other Life Sciences Tools and Diagnostics & Genomics comps.

EV/RevenueEV/EBITDA
LTM2026E2027ELTM2026E2027E
IlluminaXXXXXXXXXXXXXXXXXX
SartoriusXXXXXXXXXXXXXXXXXX
Exact SciencesXXXXXXXXXXXXXXXXXX
SterisXXXXXXXXXXXXXXXXXX
Zimmer BiometXXXXXXXXXXXXXXXXXX
HalmaXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX

Valuation data powered by FactSet, Inc.

Illumina M&A Activity

Illumina acquired XXX companies to date.

Last acquisition by Illumina was on XXXXXXXX, XXXXX. Illumina acquired XXXXXXXX for XXX (EV/Revenue multiple of XXX).

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Latest Acquisitions by Illumina

Acquired CompanyValuationEV/RevenueEV/EBITDA
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX

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Illumina Investment Activity

Illumina invested in XXX companies to date.

Illumina made its latest investment on XXXXXXXX, XXXXX. Illumina invested in XXXXXXXX for XXX (EV/Revenue multiple of XXX).

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Latest Investments by Illumina

CompanyValuationEV/RevenueEV/EBITDA
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX

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About Illumina

When was Illumina founded?Illumina was founded in 1998.
Where is Illumina headquartered?Illumina is headquartered in United States.
How many employees does Illumina have?As of today, Illumina has over 10K employees.
Who is the CEO of Illumina?Illumina's CEO is Jacob Thaysen.
Is Illumina publicly listed?Yes, Illumina is a public company listed on Nasdaq.
What is the stock symbol of Illumina?Illumina trades under ILMN ticker.
When did Illumina go public?Illumina went public in 2000.
Who are competitors of Illumina?Illumina main competitors are Sartorius, Exact Sciences, Steris, Zimmer Biomet.
What is the current market cap of Illumina?Illumina's current market cap is $20B.
What is the current revenue of Illumina?Illumina's last 12 months revenue is $4B.
What is the current revenue growth of Illumina?Illumina revenue growth (NTM/LTM) is 5%.
What is the current EV/Revenue multiple of Illumina?Current revenue multiple of Illumina is 4.9x.
Is Illumina profitable?Yes, Illumina is EBITDA-positive (as of the last 12 months).
What is the current EBITDA of Illumina?Illumina's last 12 months EBITDA is $1B.
What is Illumina's EBITDA margin?Illumina's last 12 months EBITDA margin is 28%.
What is the current EV/EBITDA multiple of Illumina?Current EBITDA multiple of Illumina is 17.2x.
What is the current FCF of Illumina?Illumina's last 12 months FCF is $887M.
What is Illumina's FCF margin?Illumina's last 12 months FCF margin is 20%.
What is the current EV/FCF multiple of Illumina?Current FCF multiple of Illumina is 24.1x.

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