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Guardant Health Valuation Multiples

Discover revenue and EBITDA valuation multiples for Guardant Health and similar public comparables like Healius, Cyclopharm, and CurveBeam AI.

Guardant Health Overview

About Guardant Health

Guardant Health, Inc, based in Redwood City, California, is a leader in liquid-based cancer tests for clinical and research use. The company offers Guardant360 LDT, a liquid biopsy test for treatment selection in advanced stage cancer, Guardant360 CDx, an FDA-approved companion diagnostic for several targeted therapies, and Guardant OMNI, a broader gene panel for immuno-oncology research. In 2021, Guardant launched Reveal, a tumor-agnostic molecular residual disease, or MRD, test. In 2024, the company received US FDA approval for Shield, a liquid biopsy for colorectal cancer, or CRC, screening. Additionally, Guardant offers research development services such as regulatory approval consultancy and clinical trial referrals.


Founded

2011

HQ

United States of America
Employees

2.0K+

Financials

LTM Revenue $799M

LTM EBITDA -$243M

EV

$5.6B

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Guardant Health Financials

Guardant Health has a last 12-month revenue (LTM) of $799M and a last 12-month EBITDA of -$243M.

In the most recent fiscal year, Guardant Health achieved revenue of $739M and an EBITDA of -$390M.

Guardant Health expects next 12-month revenue of  XXX    and NTM EBITDA of  XXX

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Guardant Health P&L

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue $799M XXX $739M XXX XXX XXX
Gross Profit $495M XXX $449M XXX XXX XXX
Gross Margin 62% XXX 61% XXX XXX XXX
EBITDA -$243M XXX -$390M XXX XXX XXX
EBITDA Margin -30% XXX -53% XXX XXX XXX
EBIT -$439M XXX -$444M XXX XXX XXX
EBIT Margin -55% XXX -60% XXX XXX XXX
Net Profit -$394M XXX -$436M XXX XXX XXX
Net Margin -49% XXX -59% XXX XXX XXX
Net Debt XXX XXX $617M XXX XXX XXX

Financial data powered by Morningstar, Inc.

Guardant Health Stock Performance

As of May 30, 2025, Guardant Health's stock price is $41.

Guardant Health has current market cap of $5.0B, and EV of $5.6B.

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Guardant Health Stock Data

EV Market Cap Price 1D Price 1M Price 3M Price 12M EPS
$5.6B $5.0B XXX XXX XXX XXX $-3.24

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Guardant Health Valuation Multiples

As of May 30, 2025, Guardant Health has market cap of $5.0B and EV of $5.6B.

Guardant Health's trades at 7.6x EV/Revenue multiple, and -14.5x EV/EBITDA.

Equity research analysts estimate Guardant Health's 2025E EV/Revenue multiple at  XXX and 2025E EV/EBITDA multiple at  XXX

Guardant Health has a P/E ratio of -12.8x.

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Guardant Health Financial Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Market cap (current) $5.0B XXX $5.0B XXX XXX XXX
EV (current) $5.6B XXX $5.6B XXX XXX XXX
EV/Revenue 7.1x XXX 7.6x XXX XXX XXX
EV/EBITDA -23.2x XXX -14.5x XXX XXX XXX
EV/EBIT -12.8x XXX -12.7x XXX XXX XXX
EV/Gross Profit 11.4x XXX n/a XXX XXX XXX
P/E -12.8x XXX -11.5x XXX XXX XXX
EV/FCF -21.3x XXX -20.5x XXX XXX XXX

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Guardant Health Margins & Growth Rates

Guardant Health's last 12 month revenue growth is 20%

Guardant Health's revenue per employee in the last FY averaged $0.4M, while opex per employee averaged $0.4M for the same period.

Guardant Health's rule of 40 is -56% (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Guardant Health's rule of X is 21% (created by Bessemer, rule of X is another metric relevant for SaaS companies only, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

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Guardant Health Operational Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue Growth 20% XXX 20% XXX XXX XXX
EBITDA Margin -30% XXX -53% XXX XXX XXX
EBITDA Growth -19% XXX n/a XXX XXX XXX
Rule of 40 -56% XXX -32% XXX XXX XXX
Bessemer Rule of X XXX XXX 21% XXX XXX XXX
Revenue per Employee XXX XXX $0.4M XXX XXX XXX
Opex per Employee XXX XXX $0.4M XXX XXX XXX
S&M Expenses to Revenue XXX XXX 49% XXX XXX XXX
G&A Expenses to Revenue XXX XXX n/a XXX XXX XXX
R&D Expenses to Revenue XXX XXX 47% XXX XXX XXX
Opex to Revenue XXX XXX 121% XXX XXX XXX

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Guardant Health Public Comps

See public comps and valuation multiples for Medical Imaging & Diagnostics and Genomics & Personalized Medicine comps
EV/Revenue EV/EBITDA
2025E 2026E 2027E 2025E 2026E 2027E
Australian Clinical Labs XXX XXX XXX XXX XXX XXX
Clarity Pharmaceuticals XXX XXX XXX XXX XXX XXX
CurveBeam AI XXX XXX XXX XXX XXX XXX
Cyclopharm XXX XXX XXX XXX XXX XXX
Healius XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX

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Guardant Health M&A and Investment Activity

Guardant Health acquired  XXX companies to date.

Last acquisition by Guardant Health was  XXXXXXXX, XXXXX XXXXX XXXXXX . Guardant Health acquired  XXXXXXXX for  XXX (EV/Revenue multiple of  XXX ).

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Latest Acquisitions by Guardant Health

Acquired Company EV EV/Revenue EV/EBITDA
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX

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About Guardant Health

When was Guardant Health founded? Guardant Health was founded in 2011.
Where is Guardant Health headquartered? Guardant Health is headquartered in United States of America.
How many employees does Guardant Health have? As of today, Guardant Health has 2.0K+ employees.
Who is the CEO of Guardant Health? Guardant Health's CEO is Mr. Helmy Eltoukhy.
Is Guardant Health publicy listed? Yes, Guardant Health is a public company listed on NAS.
What is the stock symbol of Guardant Health? Guardant Health trades under GH ticker.
When did Guardant Health go public? Guardant Health went public in 2018.
Who are competitors of Guardant Health? Similar companies to Guardant Health include e.g. Australian Clinical Labs, Clarity Pharmaceuticals, CurveBeam AI, Cyclopharm.
What is the current market cap of Guardant Health? Guardant Health's current market cap is $5.0B
What is the current revenue of Guardant Health? Guardant Health's last 12 months revenue is $799M.
What is the current revenue growth of Guardant Health? Guardant Health revenue growth (NTM/LTM) is 20%.
What is the current EV/Revenue multiple of Guardant Health? Current revenue multiple of Guardant Health is 7.1x.
Is Guardant Health profitable? Yes, Guardant Health is EBITDA-positive (as of the last 12 months).
What is the current EBITDA of Guardant Health? Guardant Health's last 12 months EBITDA is -$243M.
What is Guardant Health's EBITDA margin? Guardant Health's last 12 months EBITDA margin is -30%.
What is the current EV/EBITDA multiple of Guardant Health? Current EBITDA multiple of Guardant Health is -23.2x.
What is the current FCF of Guardant Health? Guardant Health's last 12 months FCF is -$264M.
What is Guardant Health's FCF margin? Guardant Health's last 12 months FCF margin is -33%.
What is the current EV/FCF multiple of Guardant Health? Current FCF multiple of Guardant Health is -21.3x.

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