Santhera Pharmaceuticals Valuation Multiples

Santhera Pharmaceuticals is valued at $279M as of November 2026, a 2.8x revenue multiple. In the last 12 months, Santhera Pharmaceuticals revenue was $103M and Santhera Pharmaceuticals EBITDA was ($26M).

Santhera Pharmaceuticals Overview

About Santhera Pharmaceuticals

Santhera Pharmaceuticals Holding AG is a specialty pharmaceutical company focused on the development and commercialization of products for the treatment of mitochondrial and neuromuscular diseases, an area that includes many orphan and niche indications with high unmet medical needs. It has one operating segment, namely the development and commercialization of products for the treatment of neuro-ophthalmological, pulmonary, and neuromuscular diseases. The company derives the majority of its revenue from the European Union.


Founded

2004

HQ

Switzerland

Employees

85

Financials (LTM)

Revenue: $103M
EBITDA: ($26M)

EV

$285M

Valuation Multiples

Start free trial

Valuation Multiples for 15K+ Public Comps

AdidasAirbnbAmazonCiscoCoca-ColaDellDropboxIBMIntelMcDonaldsNikeNVIDIASamsungSpotifyTeslaToyota
Browse Valuation Multiples

Santhera Pharmaceuticals Financials

Santhera Pharmaceuticals reported last 12-month revenue of $103M and negative EBITDA of ($26M).

In the same LTM period, Santhera Pharmaceuticals generated $31M in gross profit, ($26M) in EBITDA losses, and had net loss of ($58M).

Revenue (LTM)


Santhera Pharmaceuticals P&L

In the most recent fiscal year, Santhera Pharmaceuticals reported revenue of $94M and EBITDA of ($45M).

Santhera Pharmaceuticals is unprofitable as of last fiscal year, with gross margin of 20%, EBITDA margin of (48%), and net margin of (64%).

See analyst estimates for Santhera Pharmaceuticals
LTMLast FY202320242025202620272028
Revenue$103M$94M$127M$48M$94M
Gross Profit$31M$18M$123M$29M$18M
Gross Margin30%20%97%60%20%
EBITDA($26M)($45M)$97M($35M)($45M)
EBITDA Margin(26%)(48%)77%(72%)(48%)
EBIT Margin(35%)(49%)49%(85%)(49%)
Net Profit($58M)($60M)$67M($52M)($60M)
Net Margin(56%)(64%)53%(107%)(64%)
Net Debt-$31M---

Financial data powered by Morningstar, Inc.

Santhera Pharmaceuticals Stock Performance

Santhera Pharmaceuticals has current market cap of $279M, and enterprise value of $285M.

Market Cap Evolution


Santhera Pharmaceuticals' stock price is $18.21.

Santhera Pharmaceuticals share price decreased by 2.0% in the last 30 days, and increased by 20.2% in the last year.

Santhera Pharmaceuticals has an EPS (earnings per share) of $-3.91.

See more trading valuation data for Santhera Pharmaceuticals
EVMarket CapPrice 1DPrice 1MPrice 3MPrice 12MEPS
$285M$279M-2.0%-2.0%-1.5%20.2%$-3.91

Benchmark Trading Valuation Multiples by Industry

Sign up to access valuation multiples like growth-adjusted P/E, Rule of 40, next 12-month EV/Revenue, EBITDA multiples by industry, consensus analyst estimates and many more.

Start Free Trial

Santhera Pharmaceuticals Valuation Multiples

Santhera Pharmaceuticals trades at 2.8x EV/Revenue multiple, and (10.8x) EV/EBITDA.

See NTM and 2027E valuation multiples for Santhera Pharmaceuticals

EV / Revenue (LTM)


Santhera Pharmaceuticals Financial Valuation Multiples

As of November 3, 2026, Santhera Pharmaceuticals has market cap of $279M and EV of $285M.

Santhera Pharmaceuticals has a P/E ratio of (4.8x).

LTMLast FY202320242025202620272028
EV/Revenue2.8x3.0x2.2x5.9x3.0x
EV/EBITDA(10.8x)(6.3x)2.9x(8.2x)(6.3x)
EV/EBIT(7.9x)(6.2x)4.5x(7.0x)(6.2x)
EV/Gross Profit9.3x15.4x2.3x9.8x15.4x
P/E(4.8x)(4.7x)4.1x(5.4x)(4.7x)
EV/FCF(36.8x)(6.7x)9.8x(6.5x)(6.7x)

Multiples above and below 250x are considered non-meaningful (n/m). Valuation data powered by FactSet, Inc. and Morningstar, Inc.

Verified Santhera Pharmaceuticals Valuation Multiples

Access all public comps and forward-looking valuation multiples like EV/Revenue in 2027, based on consensus analyst estimates. Powered by FactSet and Morningstar.

FactSetMorningstar
Start Free Trial

Santhera Pharmaceuticals Margins & Growth Rates

Santhera Pharmaceuticals grew revenue by 11% but EBITDA decreased by 46% in the last fiscal year.

In the most recent fiscal year, Santhera Pharmaceuticals reported gross margin of 20%, EBITDA margin of (48%), and net margin of (64%).

See estimated margins and future growth rates for Santhera Pharmaceuticals

Santhera Pharmaceuticals Margins

Last FY202420252026202720282029
Gross Margin20%60%20%32%
EBITDA Margin(48%)(72%)(48%)(23%)
EBIT Margin(49%)(85%)(49%)(33%)
Net Margin(64%)(107%)(64%)(55%)
FCF Margin(45%)(91%)(45%)(1%)

Santhera Pharmaceuticals Growth Rates

FY+1/FY23/2424/2525/2626/2727/2828/29
Revenue Growth11%(62%)95%11%
Gross Profit Growth78%(76%)(36%)78%
EBITDA Growth(46%)(136%)30%(46%)
EBIT Growth(26%)(165%)12%(26%)
Net Profit Growth(5%)(177%)16%(5%)
FCF Growth(97%)(252%)(4%)(97%)

Data powered by FactSet, Inc. and Morningstar, Inc.

Santhera Pharmaceuticals Operational KPIs

Santhera Pharmaceuticals' revenue per employee in the last FY averaged $1.1M, while opex per employee averaged $0.8M for the same period.

Santhera Pharmaceuticals' Rule of 40 is (13%) (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Santhera Pharmaceuticals' Rule of X is 4% (created by Bessemer, Rule of X is another metric to measure SaaS companies, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

Access forward-looking KPIs for Santhera Pharmaceuticals
LTMLast FY202320242025202620272028
Rule of 40(3%)(13%)---
Bessemer Rule of X30%4%---
Revenue per Employee-$1.1M---
Opex per Employee-$0.8M---
S&M Expenses to Revenue17%17%9%28%17%
G&A Expenses to Revenue22%23%20%50%23%
R&D Expenses to Revenue23%29%18%68%29%
Opex to Revenue-69%47%145%69%

Data powered by FactSet, Inc. and Morningstar, Inc.

Valuation Multiples Across 230+ Verticals

Santhera Pharmaceuticals Competitors

Santhera Pharmaceuticals competitors include Fulcrum Therapeutics, Duopharma Biotech, Deva Holding, Hikal, Abclon, Rocket Pharmaceuticals, Vicore Pharma Holding, Shanghai Hile Bio-Tech, AFT Pharmaceuticals and Lavipharm.

Most Santhera Pharmaceuticals public comparables operate across Biopharmaceuticals and BioTech.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
Fulcrum Therapeutics-($73M)--(1.2x)(1.4x)
Duopharma Biotech$229M$44M1.4x1.3x7.2x6.4x
Deva Holding$385M$81M0.9x-4.1x-
Hikal$179M$15M1.9x1.8x22.6x13.1x
Abclon$4M($13M)72.1x-(20.2x)-
Rocket Pharmaceuticals-($221M)-9.6x(0.0x)(0.1x)
Vicore Pharma Holding$389K($51M)478.5x629.3x(3.6x)(4.0x)
Shanghai Hile Bio-Tech$28M($26M)9.5x-(10.4x)-

This data is available for Pro users. Sign up to see all Santhera Pharmaceuticals competitors and their valuation data.

Start Free Trial

Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples

Sign up to see data on 350K+ funding rounds and disclosed revenue and EBITDA valuation multiples, from seed, through growth stage, to pre-IPO.

Start Free Trial

About Santhera Pharmaceuticals

When was Santhera Pharmaceuticals founded?Santhera Pharmaceuticals was founded in 2004.
Where is Santhera Pharmaceuticals headquartered?Santhera Pharmaceuticals is headquartered in Switzerland.
How many employees does Santhera Pharmaceuticals have?As of today, Santhera Pharmaceuticals has over 85 employees.
Is Santhera Pharmaceuticals publicly listed?Yes, Santhera Pharmaceuticals is a public company listed on SIX Swiss Exchange.
What is the stock symbol of Santhera Pharmaceuticals?Santhera Pharmaceuticals trades under SANN ticker.
When did Santhera Pharmaceuticals go public?Santhera Pharmaceuticals went public in 2006.
Who are competitors of Santhera Pharmaceuticals?Santhera Pharmaceuticals main competitors include Fulcrum Therapeutics, Duopharma Biotech, Deva Holding, Hikal, Abclon, Rocket Pharmaceuticals, Vicore Pharma Holding, Shanghai Hile Bio-Tech, AFT Pharmaceuticals, Lavipharm.
What is the current market cap of Santhera Pharmaceuticals?Santhera Pharmaceuticals' current market cap is $279M.
What is the current revenue of Santhera Pharmaceuticals?Santhera Pharmaceuticals' last 12 months revenue is $103M.
What is the current revenue growth of Santhera Pharmaceuticals?Santhera Pharmaceuticals revenue growth (NTM/LTM) is 22%.
What is the current EV/Revenue multiple of Santhera Pharmaceuticals?Current revenue multiple of Santhera Pharmaceuticals is 2.8x.
Is Santhera Pharmaceuticals profitable?No, Santhera Pharmaceuticals is not profitable.
What is the current EBITDA of Santhera Pharmaceuticals?Santhera Pharmaceuticals has negative EBITDA and is not profitable.
What is Santhera Pharmaceuticals' EBITDA margin?Santhera Pharmaceuticals' last 12 months EBITDA margin is (26%).
What is the current EV/EBITDA multiple of Santhera Pharmaceuticals?Current EBITDA multiple of Santhera Pharmaceuticals is (10.8x).
What is the current FCF of Santhera Pharmaceuticals?Santhera Pharmaceuticals' last 12 months FCF is ($8M).
What is Santhera Pharmaceuticals' FCF margin?Santhera Pharmaceuticals' last 12 months FCF margin is (8%).
What is the current EV/FCF multiple of Santhera Pharmaceuticals?Current FCF multiple of Santhera Pharmaceuticals is (36.8x).
How many companies Santhera Pharmaceuticals has acquired to date?Santhera Pharmaceuticals hasn't acquired any companies yet (or none have been disclosed publicly).
In how many companies Santhera Pharmaceuticals has invested to date?Santhera Pharmaceuticals hasn't invested in any companies yet (or none have been disclosed publicly).

See public comps similar to Santhera Pharmaceuticals

Lists including Santhera Pharmaceuticals

Start Your
Free Trial Today

Try Multiples for free for 3 days. Got questions or need a demo? Schedule a call with us below.

Start Trial