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Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
1989
6.1K+
LTM Revenue $11.5B
LTM EBITDA $3.2B
$113B
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Vertex Pharmaceuticals has a last 12-month revenue (LTM) of $11.5B and a last 12-month EBITDA of $3.2B.
In the most recent fiscal year, Vertex Pharmaceuticals achieved revenue of $11.0B and an EBITDA of $486M.
Vertex Pharmaceuticals expects next 12-month revenue of XXX and NTM EBITDA of XXX
See Vertex Pharmaceuticals valuation multiples based on analyst estimates| LTM | NTM | Last FY | FY 2025 | FY 2026 | FY 2027 | |
|---|---|---|---|---|---|---|
| Revenue | $11.5B | XXX | $11.0B | XXX | XXX | XXX |
| Gross Profit | $9.9B | XXX | $9.5B | XXX | XXX | XXX |
| Gross Margin | 87% | XXX | 86% | XXX | XXX | XXX |
| EBITDA | $3.2B | XXX | $486M | XXX | XXX | XXX |
| EBITDA Margin | 28% | XXX | 4% | XXX | XXX | XXX |
| EBIT | $3.1B | XXX | -$233M | XXX | XXX | XXX |
| EBIT Margin | 27% | XXX | -2% | XXX | XXX | XXX |
| Net Profit | $2.4B | XXX | -$536M | XXX | XXX | XXX |
| Net Margin | 21% | XXX | -5% | XXX | XXX | XXX |
| Net Debt | XXX | XXX | n/a | XXX | XXX | XXX |
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As of July 3, 2025, Vertex Pharmaceuticals's stock price is $457.
Vertex Pharmaceuticals has current market cap of $117B, and EV of $113B.
See Vertex Pharmaceuticals trading valuation data| EV | Market Cap | Price 1D | Price 1M | Price 3M | Price 12M | EPS |
|---|---|---|---|---|---|---|
| $113B | $117B | XXX | XXX | XXX | XXX | $9.28 |
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Start Free TrialAs of July 3, 2025, Vertex Pharmaceuticals has market cap of $117B and EV of $113B.
Vertex Pharmaceuticals's trades at 10.2x EV/Revenue multiple, and 232.0x EV/EBITDA.
Equity research analysts estimate Vertex Pharmaceuticals's 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX
Vertex Pharmaceuticals has a P/E ratio of 48.7x.
See valuation multiples for Vertex Pharmaceuticals and 12K+ public comps| LTM | NTM | Last FY | FY 2025 | FY 2026 | FY 2027 | |
|---|---|---|---|---|---|---|
| Market cap (current) | $117B | XXX | $117B | XXX | XXX | XXX |
| EV (current) | $113B | XXX | $113B | XXX | XXX | XXX |
| EV/Revenue | 9.8x | XXX | 10.2x | XXX | XXX | XXX |
| EV/EBITDA | 35.6x | XXX | 232.0x | XXX | XXX | XXX |
| EV/EBIT | 36.8x | XXX | -483.3x | XXX | XXX | XXX |
| EV/Gross Profit | 11.4x | XXX | n/a | XXX | XXX | XXX |
| P/E | 48.7x | XXX | -219.1x | XXX | XXX | XXX |
| EV/FCF | 63.8x | XXX | -115.3x | XXX | XXX | XXX |
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Access all public comps and forward-looking valuation multiples like EV/Revenue in 2025, based on equity research analyst estimates.
Start Free TrialVertex Pharmaceuticals's last 12 month revenue growth is 10%
Vertex Pharmaceuticals's revenue per employee in the last FY averaged $1.8M, while opex per employee averaged $1.6M for the same period.
Vertex Pharmaceuticals's rule of 40 is 56% (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).
Vertex Pharmaceuticals's rule of X is 52% (created by Bessemer, rule of X is another metric relevant for SaaS companies only, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).
See operational valuation multiples for Vertex Pharmaceuticals and other 12K+ public comps| LTM | NTM | Last FY | FY 2025 | FY 2026 | FY 2027 | |
|---|---|---|---|---|---|---|
| Revenue Growth | 10% | XXX | 10% | XXX | XXX | XXX |
| EBITDA Margin | 28% | XXX | 4% | XXX | XXX | XXX |
| EBITDA Growth | 95% | XXX | 10% | XXX | XXX | XXX |
| Rule of 40 | 56% | XXX | 14% | XXX | XXX | XXX |
| Bessemer Rule of X | XXX | XXX | 52% | XXX | XXX | XXX |
| Revenue per Employee | XXX | XXX | $1.8M | XXX | XXX | XXX |
| Opex per Employee | XXX | XXX | $1.6M | XXX | XXX | XXX |
| S&M Expenses to Revenue | XXX | XXX | n/a | XXX | XXX | XXX |
| G&A Expenses to Revenue | XXX | XXX | n/a | XXX | XXX | XXX |
| R&D Expenses to Revenue | XXX | XXX | 75% | XXX | XXX | XXX |
| Opex to Revenue | XXX | XXX | 88% | XXX | XXX | XXX |
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Benchmark public comps and private revenue and EBITDA valuation multiples across GRC software, cloud infrastructure, DevOps, online marketplaces and so much more!
| EV/Revenue | EV/EBITDA | |||||
|---|---|---|---|---|---|---|
| 2025E | 2026E | 2027E | 2025E | 2026E | 2027E | |
| Julphar | XXX | XXX | XXX | XXX | XXX | XXX |
| Galapagos | XXX | XXX | XXX | XXX | XXX | XXX |
| Pharming | XXX | XXX | XXX | XXX | XXX | XXX |
| Vivoryon Therapeutics | XXX | XXX | XXX | XXX | XXX | XXX |
| Armata Pharmaceuticals | XXX | XXX | XXX | XXX | XXX | XXX |
| XXXXXXXX | XXX | XXX | XXX | XXX | XXX | XXX |
| XXXXXXXX | XXX | XXX | XXX | XXX | XXX | XXX |
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Vertex Pharmaceuticals acquired XXX companies to date.
Last acquisition by Vertex Pharmaceuticals was XXXXXXXX, XXXXX XXXXX XXXXXX . Vertex Pharmaceuticals acquired XXXXXXXX for XXX (EV/Revenue multiple of XXX ).
See M&A valuation multiples| Acquired Company | EV | EV/Revenue | EV/EBITDA |
|---|---|---|---|
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
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Start Free Trial| When was Vertex Pharmaceuticals founded? | Vertex Pharmaceuticals was founded in 1989. |
| Where is Vertex Pharmaceuticals headquartered? | Vertex Pharmaceuticals is headquartered in United States of America. |
| How many employees does Vertex Pharmaceuticals have? | As of today, Vertex Pharmaceuticals has 6.1K+ employees. |
| Who is the CEO of Vertex Pharmaceuticals? | Vertex Pharmaceuticals's CEO is Dr. Reshma Kewalramani, M.D.. |
| Is Vertex Pharmaceuticals publicy listed? | Yes, Vertex Pharmaceuticals is a public company listed on NAS. |
| What is the stock symbol of Vertex Pharmaceuticals? | Vertex Pharmaceuticals trades under VRTX ticker. |
| When did Vertex Pharmaceuticals go public? | Vertex Pharmaceuticals went public in 1991. |
| Who are competitors of Vertex Pharmaceuticals? | Similar companies to Vertex Pharmaceuticals include e.g. Julphar, Galapagos, Pharming, Vivoryon Therapeutics. |
| What is the current market cap of Vertex Pharmaceuticals? | Vertex Pharmaceuticals's current market cap is $117B |
| What is the current revenue of Vertex Pharmaceuticals? | Vertex Pharmaceuticals's last 12 months revenue is $11.5B. |
| What is the current revenue growth of Vertex Pharmaceuticals? | Vertex Pharmaceuticals revenue growth (NTM/LTM) is 10%. |
| What is the current EV/Revenue multiple of Vertex Pharmaceuticals? | Current revenue multiple of Vertex Pharmaceuticals is 9.8x. |
| Is Vertex Pharmaceuticals profitable? | Yes, Vertex Pharmaceuticals is EBITDA-positive (as of the last 12 months). |
| What is the current EBITDA of Vertex Pharmaceuticals? | Vertex Pharmaceuticals's last 12 months EBITDA is $3.2B. |
| What is Vertex Pharmaceuticals's EBITDA margin? | Vertex Pharmaceuticals's last 12 months EBITDA margin is 28%. |
| What is the current EV/EBITDA multiple of Vertex Pharmaceuticals? | Current EBITDA multiple of Vertex Pharmaceuticals is 35.6x. |
| What is the current FCF of Vertex Pharmaceuticals? | Vertex Pharmaceuticals's last 12 months FCF is $1.8B. |
| What is Vertex Pharmaceuticals's FCF margin? | Vertex Pharmaceuticals's last 12 months FCF margin is 15%. |
| What is the current EV/FCF multiple of Vertex Pharmaceuticals? | Current FCF multiple of Vertex Pharmaceuticals is 63.8x. |
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