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Rhythm Pharmaceuticals Inc is a commercial-stage biopharmaceutical company. It is engaged in the development and commercialization of therapies for patients with rare diseases. The company is focused on its melanocortin-4 receptor (MC4R) agonists, including its lead asset, IMCIVREE (setmelanotide), as a precision medicine designed to treat hyperphagia and severe obesity caused by rare MC4R pathway diseases. Geographically the company generates its revenue from the United States and internationally with the majority being generated from the United States.
2008
283
LTM Revenue $145M
LTM EBITDA -$239M
$3.6B
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Rhythm Pharmaceuticals has a last 12-month revenue of $145M and a last 12-month EBITDA of -$239M.
In the most recent fiscal year, Rhythm Pharmaceuticals achieved revenue of $130M and an EBITDA of -$238M.
Rhythm Pharmaceuticals expects next 12-month revenue of XXX and NTM EBITDA of XXX
See Rhythm Pharmaceuticals valuation multiples based on analyst estimates| FY 2023 | FY 2024 | FY 2025 | LTM | NTM | |
|---|---|---|---|---|---|
| Revenue | $77.4M | $130M | XXX | XXX | XXX |
| Gross Profit | $21.5M | $68.1M | XXX | XXX | XXX |
| Gross Margin | 28% | 52% | XXX | XXX | XXX |
| EBITDA | -$168M | -$238M | XXX | XXX | XXX |
| EBITDA Margin | -218% | -183% | XXX | XXX | XXX |
| Net Profit | -$181M | -$185M | XXX | XXX | XXX |
| Net Margin | -234% | -142% | XXX | XXX | XXX |
| Net Debt | n/a | n/a | XXX | XXX | XXX |
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As of April 15, 2025, Rhythm Pharmaceuticals's stock price is $60.
Rhythm Pharmaceuticals has current market cap of $3.8B, and EV of $3.6B.
See Rhythm Pharmaceuticals trading valuation data| EV | Market Cap | Price 1D | Price 1M | Price 3M | Price 12M | EPS |
|---|---|---|---|---|---|---|
| $3.6B | $3.8B | XXX | XXX | XXX | XXX | $-3.84 |
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Sign UpAs of April 15, 2025, Rhythm Pharmaceuticals has market cap of $3.8B and EV of $3.6B.
Rhythm Pharmaceuticals's trades at 24.9x LTM EV/Revenue multiple, and -15.2x LTM EBITDA.
Analysts estimate Rhythm Pharmaceuticals's 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX
See valuation multiples for Rhythm Pharmaceuticals and 10K+ public comps| FY 2024 | FY 2025E | FY 2026E | FY 2027E | |
|---|---|---|---|---|
| EV | $3.6B | XXX | XXX | XXX |
| EV/Revenue | 27.9x | XXX | XXX | XXX |
| EV/EBITDA | -15.2x | XXX | XXX | XXX |
| P/E | -14.6x | XXX | XXX | XXX |
| P/E/Growth | n/a | XXX | XXX | XXX |
| EV/FCF | -31.9x | XXX | XXX | XXX |
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Access all public comps and forward-looking valuation multiples like EV/Revenue in 2025, based on equity research analyst estimates.
Sign UpRhythm Pharmaceuticals's NTM/LTM revenue growth is 50%
Rhythm Pharmaceuticals's revenue per employee for the last fiscal year averaged $0.5M, while opex per employee averaged $1.4M for the same period.
Over next 12 months, Rhythm Pharmaceuticals's ratio of sales and marketing spend to revenue is estimated to be XXX , while its R&D spend to revenue to be XXX .
Analysts estimate Rhythm Pharmaceuticals's 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX
See operational valuation multiples for Rhythm Pharmaceuticals and other 10K+ public comps| FY 2024 | NTM | FY 2025E | FY 2026E | FY 2027E | |
|---|---|---|---|---|---|
| Revenue Growth | 68% | XXX | XXX | XXX | XXX |
| EBITDA Margin | -183% | XXX | XXX | XXX | XXX |
| EBITDA Growth | 41% | XXX | XXX | XXX | XXX |
| Rule of 40 (SaaS-only) | -133% | XXX | XXX | XXX | XXX |
| Revenue per Employee | $0.5M | XXX | XXX | XXX | XXX |
| Opex per Employee | $1.4M | XXX | XXX | XXX | XXX |
| S&M Expenses to Revenue | n/a | XXX | XXX | XXX | XXX |
| G&A Expenses to Revenue | n/a | XXX | XXX | XXX | XXX |
| R&D Expenses to Revenue | 183% | XXX | XXX | XXX | XXX |
| Opex to Revenue | 294% | XXX | XXX | XXX | XXX |
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| EV/Revenue | EV/EBITDA | |||||
|---|---|---|---|---|---|---|
| 2025E | 2026E | 2027E | 2025E | 2026E | 2027E | |
| Julphar | XXX | XXX | XXX | XXX | XXX | XXX |
| Benevolent AI | XXX | XXX | XXX | XXX | XXX | XXX |
| Galapagos | XXX | XXX | XXX | XXX | XXX | XXX |
| Pharming | XXX | XXX | XXX | XXX | XXX | XXX |
| Vivoryon Therapeutics | XXX | XXX | XXX | XXX | XXX | XXX |
| XXXXXXXX | XXX | XXX | XXX | XXX | XXX | XXX |
| XXXXXXXX | XXX | XXX | XXX | XXX | XXX | XXX |
Valuation data powered by FactSet, Inc.
Rhythm Pharmaceuticals acquired XXX companies to date.
Last acquisition by Rhythm Pharmaceuticals was XXXXXXXX, XXXXX XXXXX XXXXXX . Rhythm Pharmaceuticals acquired XXXXXXXX for XXX (EV/Revenue multiple of XXX ).
See M&A valuation multiples| Acquired Company | EV | EV/Revenue | EV/EBITDA |
|---|---|---|---|
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
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Sign Up| When was Rhythm Pharmaceuticals founded? | Rhythm Pharmaceuticals was founded in 2008. |
| Where is Rhythm Pharmaceuticals headquartered? | Rhythm Pharmaceuticals is headquartered in United States of America. |
| How many employees does Rhythm Pharmaceuticals have? | As of today, Rhythm Pharmaceuticals has 283 employees. |
| Who is the CEO of Rhythm Pharmaceuticals? | Rhythm Pharmaceuticals's CEO is Dr. David P. Meeker,M.D.. |
| Is Rhythm Pharmaceuticals publicy listed? | Yes, Rhythm Pharmaceuticals is a public company listed on NAS. |
| What is the stock symbol of Rhythm Pharmaceuticals? | Rhythm Pharmaceuticals trades under RYTM ticker. |
| When did Rhythm Pharmaceuticals go public? | Rhythm Pharmaceuticals went public in 2017. |
| Who are competitors of Rhythm Pharmaceuticals? | Similar companies to Rhythm Pharmaceuticals include e.g. Julphar, Benevolent AI, Galapagos, Pharming. |
| What is the current market cap of Rhythm Pharmaceuticals? | Rhythm Pharmaceuticals's current market cap is $3.8B |
| What is the current revenue of Rhythm Pharmaceuticals? | Rhythm Pharmaceuticals's last 12-month revenue is $145M. |
| What is the current EBITDA of Rhythm Pharmaceuticals? | Rhythm Pharmaceuticals's last 12-month EBITDA is -$239M. |
| What is the current EV/Revenue multiple of Rhythm Pharmaceuticals? | Current revenue multiple of Rhythm Pharmaceuticals is 24.9x. |
| What is the current EV/EBITDA multiple of Rhythm Pharmaceuticals? | Current EBITDA multiple of Rhythm Pharmaceuticals is -15.2x. |
| What is the current revenue growth of Rhythm Pharmaceuticals? | Rhythm Pharmaceuticals revenue growth between 2023 and 2024 was 68%. |
| Is Rhythm Pharmaceuticals profitable? | Yes, Rhythm Pharmaceuticals is EBITDA-positive (as of the last 12 months). |
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