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Cytokinetics Valuation Multiples

Discover revenue and EBITDA valuation multiples for Cytokinetics and similar public comparables like Vivoryon Therapeutics, Pharming, and Galapagos.

Cytokinetics Overview

About Cytokinetics

Cytokinetics Inc is a late-stage biopharmaceutical company focused on discovering, developing and commercializing first-in-class muscle activators and next-in-class muscle inhibitors as potential treatments for debilitating diseases in which muscle performance is compromised and/or declining. The company develops treatments for diseases such as amyotrophic lateral sclerosis, heart failure, spinal muscular atrophy, and chronic obstructive pulmonary diseases. The treatment is based on small molecules specifically engineered to increase muscle function and contractility. The company is developing muscle-directed investigational medicines that may potentially improve the health span of people with devastating cardiovascular and neuromuscular diseases of impaired muscle function.


Founded

1997

HQ

United States of America
Employees

498

Financials

LTM Revenue $20.4M

LTM EBITDA -$580M

EV

$3.6B

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Cytokinetics Financials

Cytokinetics has a last 12-month revenue (LTM) of $20.4M and a last 12-month EBITDA of -$580M.

In the most recent fiscal year, Cytokinetics achieved revenue of $18.5M and an EBITDA of -$493M.

Cytokinetics expects next 12-month revenue of  XXX    and NTM EBITDA of  XXX

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Cytokinetics P&L

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue $20.4M XXX $18.5M XXX XXX XXX
Gross Profit $19.7M XXX -$321M XXX XXX XXX
Gross Margin 97% XXX -1737% XXX XXX XXX
EBITDA -$580M XXX -$493M XXX XXX XXX
EBITDA Margin -2843% XXX -2671% XXX XXX XXX
EBIT -$585M XXX -$536M XXX XXX XXX
EBIT Margin -2867% XXX -2903% XXX XXX XXX
Net Profit -$629M XXX -$590M XXX XXX XXX
Net Margin -3083% XXX -3191% XXX XXX XXX
Net Debt XXX XXX $562M XXX XXX XXX

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Cytokinetics Stock Performance

As of May 30, 2025, Cytokinetics's stock price is $31.

Cytokinetics has current market cap of $3.7B, and EV of $3.6B.

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Cytokinetics Stock Data

EV Market Cap Price 1D Price 1M Price 3M Price 12M EPS
$3.6B $3.7B XXX XXX XXX XXX $-5.45

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Cytokinetics Valuation Multiples

As of May 30, 2025, Cytokinetics has market cap of $3.7B and EV of $3.6B.

Cytokinetics's trades at 192.6x EV/Revenue multiple, and -7.2x EV/EBITDA.

Equity research analysts estimate Cytokinetics's 2025E EV/Revenue multiple at  XXX and 2025E EV/EBITDA multiple at  XXX

Cytokinetics has a P/E ratio of -5.9x.

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Cytokinetics Financial Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Market cap (current) $3.7B XXX $3.7B XXX XXX XXX
EV (current) $3.6B XXX $3.6B XXX XXX XXX
EV/Revenue 174.3x XXX 192.6x XXX XXX XXX
EV/EBITDA -6.1x XXX -7.2x XXX XXX XXX
EV/EBIT -6.1x XXX -6.6x XXX XXX XXX
EV/Gross Profit 180.2x XXX n/a XXX XXX XXX
P/E -5.9x XXX -6.3x XXX XXX XXX
EV/FCF -13.5x XXX -8.9x XXX XXX XXX

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Cytokinetics Margins & Growth Rates

Cytokinetics's last 12 month revenue growth is 344%

Cytokinetics's revenue per employee in the last FY averaged $37K, while opex per employee averaged $0.4M for the same period.

Cytokinetics's rule of 40 is -5721% (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Cytokinetics's rule of X is -1983% (created by Bessemer, rule of X is another metric relevant for SaaS companies only, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

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Cytokinetics Operational Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue Growth 344% XXX 218% XXX XXX XXX
EBITDA Margin -2843% XXX -2671% XXX XXX XXX
EBITDA Growth 5% XXX n/a XXX XXX XXX
Rule of 40 -5721% XXX -2327% XXX XXX XXX
Bessemer Rule of X XXX XXX -1983% XXX XXX XXX
Revenue per Employee XXX XXX $37K XXX XXX XXX
Opex per Employee XXX XXX $0.4M XXX XXX XXX
S&M Expenses to Revenue XXX XXX n/a XXX XXX XXX
G&A Expenses to Revenue XXX XXX n/a XXX XXX XXX
R&D Expenses to Revenue XXX XXX n/a XXX XXX XXX
Opex to Revenue XXX XXX 1165% XXX XXX XXX

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Cytokinetics Public Comps

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EV/Revenue EV/EBITDA
2025E 2026E 2027E 2025E 2026E 2027E
Julphar XXX XXX XXX XXX XXX XXX
Benevolent AI XXX XXX XXX XXX XXX XXX
Galapagos XXX XXX XXX XXX XXX XXX
Pharming XXX XXX XXX XXX XXX XXX
Vivoryon Therapeutics XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX

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Cytokinetics M&A and Investment Activity

Cytokinetics acquired  XXX companies to date.

Last acquisition by Cytokinetics was  XXXXXXXX, XXXXX XXXXX XXXXXX . Cytokinetics acquired  XXXXXXXX for  XXX (EV/Revenue multiple of  XXX ).

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Latest Acquisitions by Cytokinetics

Acquired Company EV EV/Revenue EV/EBITDA
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX

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About Cytokinetics

When was Cytokinetics founded? Cytokinetics was founded in 1997.
Where is Cytokinetics headquartered? Cytokinetics is headquartered in United States of America.
How many employees does Cytokinetics have? As of today, Cytokinetics has 498 employees.
Who is the CEO of Cytokinetics? Cytokinetics's CEO is Mr. Robert I. Blum.
Is Cytokinetics publicy listed? Yes, Cytokinetics is a public company listed on NAS.
What is the stock symbol of Cytokinetics? Cytokinetics trades under CYTK ticker.
When did Cytokinetics go public? Cytokinetics went public in 2004.
Who are competitors of Cytokinetics? Similar companies to Cytokinetics include e.g. Julphar, Benevolent AI, Galapagos, Pharming.
What is the current market cap of Cytokinetics? Cytokinetics's current market cap is $3.7B
What is the current revenue of Cytokinetics? Cytokinetics's last 12 months revenue is $20.4M.
What is the current revenue growth of Cytokinetics? Cytokinetics revenue growth (NTM/LTM) is 344%.
What is the current EV/Revenue multiple of Cytokinetics? Current revenue multiple of Cytokinetics is 174.3x.
Is Cytokinetics profitable? Yes, Cytokinetics is EBITDA-positive (as of the last 12 months).
What is the current EBITDA of Cytokinetics? Cytokinetics's last 12 months EBITDA is -$580M.
What is Cytokinetics's EBITDA margin? Cytokinetics's last 12 months EBITDA margin is -2843%.
What is the current EV/EBITDA multiple of Cytokinetics? Current EBITDA multiple of Cytokinetics is -6.1x.
What is the current FCF of Cytokinetics? Cytokinetics's last 12 months FCF is -$263M.
What is Cytokinetics's FCF margin? Cytokinetics's last 12 months FCF margin is -1288%.
What is the current EV/FCF multiple of Cytokinetics? Current FCF multiple of Cytokinetics is -13.5x.

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