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Cytokinetics Valuation Multiples

Discover revenue and EBITDA valuation multiples for Cytokinetics and similar public comparables like Ono Pharmaceutical, ALK, Aurobindo Pharma, Grifols and more.

Cytokinetics Overview

About Cytokinetics

Cytokinetics Inc is a late-stage biopharmaceutical company focused on discovering, developing and commercializing first-in-class muscle activators and next-in-class muscle inhibitors as potential treatments for debilitating diseases in which muscle performance is compromised and/or declining. The company develops treatments for diseases such as amyotrophic lateral sclerosis, heart failure, spinal muscular atrophy, and chronic obstructive pulmonary diseases. The treatment is based on small molecules specifically engineered to increase muscle function and contractility. The company is developing muscle-directed investigational medicines that may potentially improve the health span of people with devastating cardiovascular and neuromuscular diseases of impaired muscle function.


Founded

1997

HQ

United States

Employees

498

Financials (LTM)

Revenue: $89M
EBITDA: ($636M)

EV

$8B

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Cytokinetics Financials

Cytokinetics reported last 12-month revenue of $89M and negative EBITDA of ($636M).

In the same LTM period, Cytokinetics generated $88M in gross profit, ($636M) in EBITDA losses, and had net loss of ($788M).

Revenue (LTM)


Cytokinetics P&L

In the most recent fiscal year, Cytokinetics reported revenue of $88M and EBITDA of ($606M).

Cytokinetics expects next 12-month revenue of XXX and NTM EBITDA of XXX

See Cytokinetics forward-looking valuation multiples
LTMNTMLast FYFY 2026FY 2027FY 2028
Revenue$89MXXX$88MXXXXXXXXX
Gross Profit$88MXXX($328M)XXXXXXXXX
Gross Margin98%XXX(373%)XXXXXXXXX
EBITDA($636M)XXX($606M)XXXXXXXXX
EBITDA Margin(714%)XXX(688%)XXXXXXXXX
EBIT Margin(721%)XXX(695%)XXXXXXXXX
Net Profit($788M)XXX($785M)XXXXXXXXX
Net Margin(885%)XXX(892%)XXXXXXXXX
Net Debt——$1BXXXXXXXXX

Financial data powered by Morningstar, Inc.

Cytokinetics Stock Performance

Cytokinetics has current market cap of $8B, and enterprise value of $8B.

Market Cap Evolution


Cytokinetics' stock price is $61.46.

See Cytokinetics trading valuation data
EVMarket CapPrice 1DPrice 1MPrice 3MPrice 12MEPS
$8B$8B0.0%XXXXXXXXX$-6.42

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Cytokinetics Valuation Multiples

Cytokinetics trades at 87.0x EV/Revenue multiple, and (12.2x) EV/EBITDA.

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EV / Revenue (LTM)


Cytokinetics Financial Valuation Multiples

As of March 24, 2026, Cytokinetics has market cap of $8B and EV of $8B.

Equity research analysts estimate Cytokinetics' 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX

Cytokinetics has a P/E ratio of (9.5x).

LTMNTMLast FYFY 2026FY 2027FY 2028
Market cap (current)$8BXXX$8BXXXXXXXXX
EV (current)$8BXXX$8BXXXXXXXXX
EV/Revenue87.0xXXX88.0xXXXXXXXXX
EV/EBITDA(12.2x)XXX(12.8x)XXXXXXXXX
EV/EBIT(12.1x)XXX(12.7x)XXXXXXXXX
EV/Gross Profit88.4xXXX(23.6x)XXXXXXXXX
P/E(9.5x)XXX(9.6x)XXXXXXXXX
EV/FCF288.5xXXX(25.5x)XXXXXXXXX

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Cytokinetics Margins & Growth Rates

Cytokinetics' revenue in the last 12 month grew by 78%.

Cytokinetics' revenue per employee in the last FY averaged $0.2M.

Cytokinetics' rule of 40 is (636%) (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Cytokinetics' rule of X is (518%) (created by Bessemer, rule of X is another metric to measure SaaS companies, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

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Cytokinetics Operational Valuation Multiples

LTMNTMLast FYFY 2026FY 2027FY 2028
Revenue Growth78%XXX5%XXXXXXXXX
EBITDA Margin(714%)XXX(688%)XXXXXXXXX
EBITDA Growth7%XXX22%XXXXXXXXX
Rule of 40—XXX(636%)XXXXXXXXX
Bessemer Rule of X—XXX(518%)XXXXXXXXX
Revenue per Employee—XXX$0.2MXXXXXXXXX
G&A Expenses to Revenue348%XXX323%XXXXXXXXX
R&D Expenses to Revenue472%XXX—XXXXXXXXX
Opex to Revenue—XXX323%XXXXXXXXX

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Cytokinetics Public Comps

See public comps and valuation multiples for other Biopharmaceuticals comps.

EV/RevenueEV/EBITDA
LTM2026E2027ELTM2026E2027E
Ono PharmaceuticalXXXXXXXXXXXXXXXXXX
ALKXXXXXXXXXXXXXXXXXX
Aurobindo PharmaXXXXXXXXXXXXXXXXXX
GrifolsXXXXXXXXXXXXXXXXXX
Krystal BiotechXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX

Valuation data powered by FactSet, Inc.

Cytokinetics M&A Activity

Cytokinetics acquired XXX companies to date.

Last acquisition by Cytokinetics was on XXXXXXXX, XXXXX. Cytokinetics acquired XXXXXXXX for XXX (EV/Revenue multiple of XXX).

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Latest Acquisitions by Cytokinetics

Acquired CompanyValuationEV/RevenueEV/EBITDA
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX

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Cytokinetics Investment Activity

Cytokinetics invested in XXX companies to date.

Cytokinetics made its latest investment on XXXXXXXX, XXXXX. Cytokinetics invested in XXXXXXXX for XXX (EV/Revenue multiple of XXX).

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Latest Investments by Cytokinetics

CompanyValuationEV/RevenueEV/EBITDA
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX

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About Cytokinetics

When was Cytokinetics founded?Cytokinetics was founded in 1997.
Where is Cytokinetics headquartered?Cytokinetics is headquartered in United States.
How many employees does Cytokinetics have?As of today, Cytokinetics has over 498 employees.
Who is the CEO of Cytokinetics?Cytokinetics' CEO is Robert I. Blum.
Is Cytokinetics publicly listed?Yes, Cytokinetics is a public company listed on Nasdaq.
What is the stock symbol of Cytokinetics?Cytokinetics trades under CYTK ticker.
When did Cytokinetics go public?Cytokinetics went public in 2004.
Who are competitors of Cytokinetics?Cytokinetics main competitors are Ono Pharmaceutical, ALK, Aurobindo Pharma, Grifols.
What is the current market cap of Cytokinetics?Cytokinetics' current market cap is $8B.
What is the current revenue of Cytokinetics?Cytokinetics' last 12 months revenue is $89M.
What is the current revenue growth of Cytokinetics?Cytokinetics revenue growth (NTM/LTM) is 78%.
What is the current EV/Revenue multiple of Cytokinetics?Current revenue multiple of Cytokinetics is 87.0x.
Is Cytokinetics profitable?No, Cytokinetics is not profitable.
What is the current EBITDA of Cytokinetics?Cytokinetics has negative EBITDA and is not profitable.
What is Cytokinetics' EBITDA margin?Cytokinetics' last 12 months EBITDA margin is (714%).
What is the current EV/EBITDA multiple of Cytokinetics?Current EBITDA multiple of Cytokinetics is (12.2x).
What is the current FCF of Cytokinetics?Cytokinetics' last 12 months FCF is $27M.
What is Cytokinetics' FCF margin?Cytokinetics' last 12 months FCF margin is 30%.
What is the current EV/FCF multiple of Cytokinetics?Current FCF multiple of Cytokinetics is 288.5x.

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