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Ono Pharmaceutical Valuation Multiples

Discover revenue and EBITDA valuation multiples for Ono Pharmaceutical and similar public comparables like Vivoryon Therapeutics, Julphar, and Pharming.

Ono Pharmaceutical Overview

About Ono Pharmaceutical

Ono Pharmaceutical Co Ltd is a drug manufacturer with a focus on drug discovery in areas of unmet medical needs. It maintains a world-wide business in specialty pharmaceuticals. The company breaks out its revenue of goods and products into eight segments. The vast majority of Ono's revenue is derived from its circulatory and respiratory drugs, followed by its metabolic drugs and vitamins. The company also reports revenue derived from royalties. The bulk of Ono's sales are generated in Japan, followed by the rest of Asia and Europe.


Founded

1947

HQ

Japan
Employees

3.6K+

Website

ono.co.jp

Financials

LTM Revenue $3.4B

LTM EBITDA $784M

EV

$4.6B

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Ono Pharmaceutical Financials

Ono Pharmaceutical has a last 12-month revenue (LTM) of $3.4B and a last 12-month EBITDA of $784M.

In the most recent fiscal year, Ono Pharmaceutical achieved revenue of $3.4B and an EBITDA of $1.2B.

Ono Pharmaceutical expects next 12-month revenue of  XXX    and NTM EBITDA of  XXX

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Ono Pharmaceutical P&L

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue $3.4B XXX $3.4B XXX XXX XXX
Gross Profit $2.5B XXX $2.6B XXX XXX XXX
Gross Margin 75% XXX 75% XXX XXX XXX
EBITDA $784M XXX $1.2B XXX XXX XXX
EBITDA Margin 23% XXX 36% XXX XXX XXX
EBIT $750M XXX $1.1B XXX XXX XXX
EBIT Margin 22% XXX 32% XXX XXX XXX
Net Profit $594M XXX $878M XXX XXX XXX
Net Margin 18% XXX 25% XXX XXX XXX
Net Debt XXX XXX n/a XXX XXX XXX

Financial data powered by Morningstar, Inc.

Ono Pharmaceutical Stock Performance

As of May 30, 2025, Ono Pharmaceutical's stock price is JPY 1565 (or $11).

Ono Pharmaceutical has current market cap of JPY 735B (or $5.0B), and EV of JPY 672B (or $4.6B).

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Ono Pharmaceutical Stock Data

EV Market Cap Price 1D Price 1M Price 3M Price 12M EPS
$4.6B $5.0B XXX XXX XXX XXX $0.77

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Ono Pharmaceutical Valuation Multiples

As of May 30, 2025, Ono Pharmaceutical has market cap of $5.0B and EV of $4.6B.

Ono Pharmaceutical's trades at 1.4x EV/Revenue multiple, and 3.8x EV/EBITDA.

Equity research analysts estimate Ono Pharmaceutical's 2025E EV/Revenue multiple at  XXX and 2025E EV/EBITDA multiple at  XXX

Ono Pharmaceutical has a P/E ratio of 8.5x.

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Ono Pharmaceutical Financial Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Market cap (current) $5.0B XXX $5.0B XXX XXX XXX
EV (current) $4.6B XXX $4.6B XXX XXX XXX
EV/Revenue 1.4x XXX 1.4x XXX XXX XXX
EV/EBITDA 5.9x XXX 3.8x XXX XXX XXX
EV/EBIT 6.1x XXX 4.3x XXX XXX XXX
EV/Gross Profit 1.8x XXX n/a XXX XXX XXX
P/E 8.5x XXX 5.9x XXX XXX XXX
EV/FCF 8.2x XXX 6.5x XXX XXX XXX

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Ono Pharmaceutical Margins & Growth Rates

Ono Pharmaceutical's last 12 month revenue growth is 2%

Ono Pharmaceutical's revenue per employee in the last FY averaged $1.0M, while opex per employee averaged $0.4M for the same period.

Ono Pharmaceutical's rule of 40 is 38% (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Ono Pharmaceutical's rule of X is 28% (created by Bessemer, rule of X is another metric relevant for SaaS companies only, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

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Ono Pharmaceutical Operational Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue Growth 2% XXX 1% XXX XXX XXX
EBITDA Margin 23% XXX 36% XXX XXX XXX
EBITDA Growth 7% XXX -16% XXX XXX XXX
Rule of 40 38% XXX 38% XXX XXX XXX
Bessemer Rule of X XXX XXX 28% XXX XXX XXX
Revenue per Employee XXX XXX $1.0M XXX XXX XXX
Opex per Employee XXX XXX $0.4M XXX XXX XXX
S&M Expenses to Revenue XXX XXX n/a XXX XXX XXX
G&A Expenses to Revenue XXX XXX n/a XXX XXX XXX
R&D Expenses to Revenue XXX XXX 22% XXX XXX XXX
Opex to Revenue XXX XXX 43% XXX XXX XXX

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Ono Pharmaceutical Public Comps

See public comps and valuation multiples for Biopharmaceuticals and Drug Development & Therapeutics comps
EV/Revenue EV/EBITDA
2025E 2026E 2027E 2025E 2026E 2027E
Julphar XXX XXX XXX XXX XXX XXX
Galapagos XXX XXX XXX XXX XXX XXX
Pharming XXX XXX XXX XXX XXX XXX
Vivoryon Therapeutics XXX XXX XXX XXX XXX XXX
Armata Pharmaceuticals XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX

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Ono Pharmaceutical M&A and Investment Activity

Ono Pharmaceutical acquired  XXX companies to date.

Last acquisition by Ono Pharmaceutical was  XXXXXXXX, XXXXX XXXXX XXXXXX . Ono Pharmaceutical acquired  XXXXXXXX for  XXX (EV/Revenue multiple of  XXX ).

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Latest Acquisitions by Ono Pharmaceutical

Acquired Company EV EV/Revenue EV/EBITDA
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX

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About Ono Pharmaceutical

When was Ono Pharmaceutical founded? Ono Pharmaceutical was founded in 1947.
Where is Ono Pharmaceutical headquartered? Ono Pharmaceutical is headquartered in Japan.
How many employees does Ono Pharmaceutical have? As of today, Ono Pharmaceutical has 3.6K+ employees.
Who is the CEO of Ono Pharmaceutical? Ono Pharmaceutical's CEO is Mr. Gyo Sagara.
Is Ono Pharmaceutical publicy listed? Yes, Ono Pharmaceutical is a public company listed on TKS.
What is the stock symbol of Ono Pharmaceutical? Ono Pharmaceutical trades under 4528 ticker.
When did Ono Pharmaceutical go public? Ono Pharmaceutical went public in 1963.
Who are competitors of Ono Pharmaceutical? Similar companies to Ono Pharmaceutical include e.g. Julphar, Galapagos, Pharming, Vivoryon Therapeutics.
What is the current market cap of Ono Pharmaceutical? Ono Pharmaceutical's current market cap is $5.0B
What is the current revenue of Ono Pharmaceutical? Ono Pharmaceutical's last 12 months revenue is $3.4B.
What is the current revenue growth of Ono Pharmaceutical? Ono Pharmaceutical revenue growth (NTM/LTM) is 2%.
What is the current EV/Revenue multiple of Ono Pharmaceutical? Current revenue multiple of Ono Pharmaceutical is 1.4x.
Is Ono Pharmaceutical profitable? Yes, Ono Pharmaceutical is EBITDA-positive (as of the last 12 months).
What is the current EBITDA of Ono Pharmaceutical? Ono Pharmaceutical's last 12 months EBITDA is $784M.
What is Ono Pharmaceutical's EBITDA margin? Ono Pharmaceutical's last 12 months EBITDA margin is 23%.
What is the current EV/EBITDA multiple of Ono Pharmaceutical? Current EBITDA multiple of Ono Pharmaceutical is 5.9x.
What is the current FCF of Ono Pharmaceutical? Ono Pharmaceutical's last 12 months FCF is $564M.
What is Ono Pharmaceutical's FCF margin? Ono Pharmaceutical's last 12 months FCF margin is 17%.
What is the current EV/FCF multiple of Ono Pharmaceutical? Current FCF multiple of Ono Pharmaceutical is 8.2x.

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