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Oruka Therapeutics Valuation Multiples

Discover revenue and EBITDA valuation multiples for Oruka Therapeutics and similar public comparables like Sionna Therapeutics, Nanobiotix, Square Pharma, Agios Pharmaceuticals and more.

Oruka Therapeutics Overview

About Oruka Therapeutics

Oruka Therapeutics Inc is a clinical-stage biopharmaceutical company focused on developing novel monoclonal antibody therapeutics for psoriasis (PsO) and other inflammatory and immunology (I&I) indications. Its lead program, ORKA-001, is designed to target the p19 subunit of interleukin-23 (IL-23p19) for the treatment of PsO. The company's co-lead program, ORKA-002, is designed to target interleukin-17A and interleukin-17F (IL-17A/F) for the treatment of PsO, psoriatic arthritis (PsA), and other conditions. These programs each bind their respective targets at high affinity and incorporate half-life extension technology to increase exposure and decreasing dosing frequency.


Founded

2024

HQ

United States

Employees

36

Financials (LTM)

Revenue:
EBITDA: ($130M)

EV

$1B

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Oruka Therapeutics Financials

Oruka Therapeutics reported last 12-month revenue of — and negative EBITDA of ($130M).

In the same LTM period, Oruka Therapeutics generated — in gross profit, ($130M) in EBITDA losses, and had net loss of ($117M).

Revenue (LTM)


Oruka Therapeutics P&L

In the most recent fiscal year, Oruka Therapeutics reported revenue of and net income of .

Oruka Therapeutics expects next 12-month revenue of XXX and NTM EBITDA of XXX

See Oruka Therapeutics forward-looking valuation multiples
LTMNTMLast FYFY 2026FY 2027FY 2028
EBITDA($130M)XXXXXXXXXXXX
Net Profit($117M)XXXXXXXXXXXX

Financial data powered by Morningstar, Inc.

Oruka Therapeutics Stock Performance

Oruka Therapeutics has current market cap of $2B, and enterprise value of $1B.

Market Cap Evolution


Oruka Therapeutics' stock price is $33.63.

See Oruka Therapeutics trading valuation data
EVMarket CapPrice 1DPrice 1MPrice 3MPrice 12MEPS
$1B$2B0.0%XXXXXXXXX

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Oruka Therapeutics Valuation Multiples

Oruka Therapeutics trades at (9.8x) EV/EBITDA.

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Oruka Therapeutics Financial Valuation Multiples

As of March 7, 2026, Oruka Therapeutics has market cap of $2B and EV of $1B.

Equity research analysts estimate Oruka Therapeutics' 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX

Oruka Therapeutics has a P/E ratio of (13.9x).

LTMNTMLast FYFY 2026FY 2027FY 2028
Market cap (current)$2BXXX$2BXXXXXXXXX
EV (current)$1BXXX$1BXXXXXXXXX
EV/EBITDA(9.8x)XXXXXXXXXXXX
EV/EBIT(9.9x)XXXXXXXXXXXX
P/E(13.9x)XXXXXXXXXXXX

Valuation data powered by FactSet, Inc. and Morningstar, Inc.

Verified Oruka Therapeutics Valuation Multiples

Access all public comps and forward-looking valuation multiples like EV/Revenue in 2027, based on consensus analyst estimates. Powered by FactSet and Morningstar.

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Oruka Therapeutics Margins & Growth Rates

Oruka Therapeutics' revenue in the last fiscal year grew by .

Oruka Therapeutics' revenue per employee in the last FY averaged $0.0M.

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Oruka Therapeutics Operational Valuation Multiples

LTMNTMLast FYFY 2026FY 2027FY 2028
EBITDA Growth25%XXXXXXXXXXXX
Revenue per EmployeeXXX$0.0MXXXXXXXXX

Valuation data powered by FactSet, Inc. and Morningstar, Inc.

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Oruka Therapeutics Public Comps

See public comps and valuation multiples for other Biopharmaceuticals comps.

EV/RevenueEV/EBITDA
LTM2026E2027ELTM2026E2027E
Sionna TherapeuticsXXXXXXXXXXXXXXXXXX
NanobiotixXXXXXXXXXXXXXXXXXX
Square PharmaXXXXXXXXXXXXXXXXXX
Agios PharmaceuticalsXXXXXXXXXXXXXXXXXX
Immunocore HoldingsXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX

Valuation data powered by FactSet, Inc.

Oruka Therapeutics M&A Activity

Oruka Therapeutics acquired XXX companies to date.

Last acquisition by Oruka Therapeutics was on XXXXXXXX, XXXXX. Oruka Therapeutics acquired XXXXXXXX for XXX (EV/Revenue multiple of XXX).

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Latest Acquisitions by Oruka Therapeutics

Acquired CompanyValuationEV/RevenueEV/EBITDA
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX

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Oruka Therapeutics Investment Activity

Oruka Therapeutics invested in XXX companies to date.

Oruka Therapeutics made its latest investment on XXXXXXXX, XXXXX. Oruka Therapeutics invested in XXXXXXXX for XXX (EV/Revenue multiple of XXX).

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Latest Investments by Oruka Therapeutics

CompanyValuationEV/RevenueEV/EBITDA
XXXXXXXXXXXXXXXXXXXXX
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XXXXXXXXXXXXXXXXXXXXX
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About Oruka Therapeutics

When was Oruka Therapeutics founded?Oruka Therapeutics was founded in 2024.
Where is Oruka Therapeutics headquartered?Oruka Therapeutics is headquartered in United States.
How many employees does Oruka Therapeutics have?As of today, Oruka Therapeutics has over 36 employees.
Who is the CEO of Oruka Therapeutics?Oruka Therapeutics' CEO is Lawrence Otto Klein.
Is Oruka Therapeutics publicly listed?Yes, Oruka Therapeutics is a public company listed on Nasdaq.
What is the stock symbol of Oruka Therapeutics?Oruka Therapeutics trades under ORKA ticker.
When did Oruka Therapeutics go public?Oruka Therapeutics went public in 2024.
Who are competitors of Oruka Therapeutics?Oruka Therapeutics main competitors are Sionna Therapeutics, Nanobiotix, Square Pharma, Agios Pharmaceuticals.
What is the current market cap of Oruka Therapeutics?Oruka Therapeutics' current market cap is $2B.
Is Oruka Therapeutics profitable?No, Oruka Therapeutics is not profitable.
What is the current EBITDA of Oruka Therapeutics?Oruka Therapeutics has negative EBITDA and is not profitable.
What is the current EV/EBITDA multiple of Oruka Therapeutics?Current EBITDA multiple of Oruka Therapeutics is (9.8x).

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