GenFleet Therapeutics Valuation Multiples

GenFleet Therapeutics is valued at $1.1B as of November 2026, a 48.1x revenue multiple. In the last 12 months, GenFleet Therapeutics revenue was $17M and GenFleet Therapeutics EBITDA was ($115M).

GenFleet Therapeutics Overview

About GenFleet Therapeutics

GenFleet Therapeutics (Shanghai) Inc is a biopharmaceutical company focused on developing novel treatment options in the fields of oncology, covering different lines of treatments of multiple solid tumors, as well as autoimmune and inflammatory diseases. It has established a product pipeline consisting of eight product candidates with five under clinical development, including two Core Products - GFH925 and GFH375. GFH925 is an in-house discovered new drug, has been approved for commercialization in China for the treatment of advanced non-small cell lung cancer.


Founded

2017

HQ

China

Employees

90

Financials (LTM)

Revenue: $17M
EBITDA: ($115M)

EV

$817M

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GenFleet Therapeutics Financials

GenFleet Therapeutics reported last 12-month revenue of $17M and negative EBITDA of ($115M).

In the same LTM period, GenFleet Therapeutics generated $11M in gross profit, ($115M) in EBITDA losses, and had net loss of ($106M).


GenFleet Therapeutics P&L

In the most recent fiscal year, GenFleet Therapeutics reported revenue of $20M and EBITDA of ($272M).

GenFleet Therapeutics is unprofitable as of last fiscal year, with gross margin of 64%, EBITDA margin of (1389%), and net margin of (1378%).

See analyst estimates for GenFleet Therapeutics
LTMLast FY2025202620272028
Revenue$17M$20M$20M
Gross Profit$11M$13M$13M
Gross Margin65%64%64%
EBITDA($115M)($272M)($272M)
EBITDA Margin(676%)(1389%)(1389%)
EBIT Margin(462%)(212%)(212%)
Net Profit($106M)($269M)($269M)
Net Margin(623%)(1378%)(1378%)
Net Debt-($165M)-

Financial data powered by Morningstar, Inc.

GenFleet Therapeutics Stock Performance

GenFleet Therapeutics has current market cap of $1.1B, and enterprise value of $817M.

Market Cap Evolution


GenFleet Therapeutics' stock price is $2.78.

GenFleet Therapeutics has an EPS (earnings per share) of $-0.71.

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EVMarket CapPrice 1DPrice 1MPrice 3MPrice 12MEPS
$817M$1.1B0.0%---$-0.71

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GenFleet Therapeutics Valuation Multiples

GenFleet Therapeutics trades at 48.1x EV/Revenue multiple, and (7.1x) EV/EBITDA.

See NTM and 2027E valuation multiples for GenFleet Therapeutics

GenFleet Therapeutics Financial Valuation Multiples

As of November 9, 2026, GenFleet Therapeutics has market cap of $1.1B and EV of $817M.

GenFleet Therapeutics has a P/E ratio of (10.0x).

LTMLast FY2025202620272028
EV/Revenue48.1x41.8x41.8x
EV/EBITDA(7.1x)(3.0x)(3.0x)
EV/EBIT(10.4x)(19.7x)(19.7x)
EV/Gross Profit74.0x65.0x65.0x
P/E(10.0x)(3.9x)(3.9x)
EV/FCF(16.6x)(39.1x)(39.1x)

Multiples above and below 250x are considered non-meaningful (n/m). Valuation data powered by FactSet, Inc. and Morningstar, Inc.

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GenFleet Therapeutics Margins & Growth Rates

GenFleet Therapeutics decreased revenue by 15% and EBITDA by 67% in the last fiscal year.

In the most recent fiscal year, GenFleet Therapeutics reported gross margin of 64%, EBITDA margin of (1389%), and net margin of (1378%).

See estimated margins and future growth rates for GenFleet Therapeutics

GenFleet Therapeutics Margins

Last FY20252026202720282029
Gross Margin64%64%65%
EBITDA Margin(1389%)(1389%)(543%)
EBIT Margin(212%)(212%)(400%)
Net Margin(1378%)(1378%)(477%)
FCF Margin(107%)(107%)(330%)

GenFleet Therapeutics Growth Rates

FY+1/FY25/2626/2727/2828/29
Revenue Growth(15%)(15%)
Gross Profit Growth(14%)(14%)
EBITDA Growth(67%)(67%)
EBIT Growth60%60%
Net Profit Growth(71%)(71%)
FCF Growth163%163%

Data powered by FactSet, Inc. and Morningstar, Inc.

GenFleet Therapeutics Operational KPIs

GenFleet Therapeutics' revenue per employee in the last FY averaged $0.2M, while opex per employee averaged $0.6M for the same period.

GenFleet Therapeutics' Rule of 40 is (558%) (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

GenFleet Therapeutics' Rule of X is (581%) (created by Bessemer, Rule of X is another metric to measure SaaS companies, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

Access forward-looking KPIs for GenFleet Therapeutics
LTMLast FY2025202620272028
Rule of 40(561%)(558%)-
Bessemer Rule of X(389%)(581%)-
Revenue per Employee-$0.2M-
Opex per Employee-$0.6M-
S&M Expenses to Revenue2%0%0%
G&A Expenses to Revenue75%62%62%
R&D Expenses to Revenue344%217%217%
Opex to Revenue-277%277%

Data powered by FactSet, Inc. and Morningstar, Inc.

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GenFleet Therapeutics Competitors

GenFleet Therapeutics competitors include Verastem, Star Lake Bioscience, Viyash Scientific, Basilea Pharmaceutica, Janux Therapeutics, Symbiotec Pharmalab, CStone Pharmaceuticals, TOWA Pharmaceutical, Oscotec and Freenome.

Most GenFleet Therapeutics public comparables operate across Biopharmaceuticals and BioTech.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
Verastem$31M($212M)32.9x10.3x(4.8x)-
Star Lake Bioscience$2.4B$316M0.8x0.9x6.3x10.0x
Viyash Scientific$357M$68M3.1x2.8x16.6x15.4x
Basilea Pharmaceutica$284M$61M3.4x2.9x15.9x8.7x
Janux Therapeutics$10M($156M)15.3x6.2x(1.0x)(1.1x)
Symbiotec Pharmalab$92M$25M11.6x-43.5x-
CStone Pharmaceuticals$40M($57M)22.5x15.2x(16.1x)(15.0x)
TOWA Pharmaceutical$1.7B$240M1.3x1.2x9.2x7.0x

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GenFleet Therapeutics VC Funding History

Before going public, GenFleet Therapeutics raised $224M in total equity funding, across 5 rounds.

Last private valuation of GenFleet Therapeutics was $418M, after raising $76M in December 2021 from Suxin Venture Capital, Baidu Ventures, ABC International, and 9 other investors.


GenFleet Therapeutics Funding Rounds

DateStageInvestorsRaisedValuationRev. MultipleDeal Summary
Dec-21Series CSuxin Venture Capital; Baidu Ventures; ABC International; Shanjin Capital; Dyee Capital; Qiaojing Capital; Wenzhou Capital; Huimei Capital; Huagai Capital; Pan-Lin Capital; Qingchi Capital; CDH Investments$76M$418MGenFleet Therapeutics is a clinical-stage biotechnology company based in Shanghai focused on developing cutting-edge therapies in oncology and immunology. The company has established a proprietary R&D platform based on deep understanding of disease biology and translational medicine, with a differentiated pipeline spanning both small molecules and biologics. The company's core products include GFH925, a selective KRASG12C inhibitor for NSCLC and colorectal cancer treatment (also known as fulzerasib, marketed in China as Dupert), and GFH375, a KRASG12D inhibitor in clinical development. On December 31, 2021, GenFleet completed a Series C financing round of $75 million (approximately 500 million RMB) led by Huagai Capital, with participation from new investors including Suxin Venture Capital, Cherami Investment Group, ABC International, DYEE Capital, Qiaojing Eastern Investment, Baidu Venture, and Wenzhou Capital. The round was designed to advance the company's innovative pipeline and clinical programs. Since incorporation, GenFleet has completed multiple funding rounds raising approximately RMB 1.421 billion total from investors including Qiming Venture Partners, Huagai Capital, and Asia Investment Capital. Later rounds included a Series C+ in 2024 raising approximately RMB 195 million. The company generated RMB 73.73 million in revenue in 2023 and RMB 105 million in 2024, though it recorded significant net losses of RMB 508 million and RMB 678 million respectively during those periods, primarily driven by substantial R&D investments and fair value changes in equity share redemption liabilities.
Aug-20Series BSinopharm Capital; South China Venture Capital; Shenzhen Capital Group; Honghui Capital; Pan-Lin Capital; Qingchi Capital; CDH Investments$58M--
Mar-20Series BSinopharm Capital; South China Venture Capital; Blue Lake Capital; Highlight Capital; Shenzhen Capital Group; Pan-Lin Capital; CDH Investments$57M-GenFleet Therapeutics, a clinical-stage biotechnology company founded in 2017, focuses on developing cutting-edge small molecule and biologic therapies for oncology and immunology, with a pipeline of more than 10 product candidates, several in clinical trials. The Series B round, closed in early 2020 around March 8, raised nearly 400 million RMB (~$57.7M-$58M), co-led by CDH Investments and Shenzhen Capital Group, with participation from new investors South China Venture Capital and Panlin Capital, and existing investors Sinopharm Capital, Lake Bleu Capital (or Blue Lake Capital), and Highlight Capital. Proceeds were allocated to advance clinical projects including local trials and overseas IND applications, expand the immunology platform, launch new R&D programs, and construct commercialization sites in the Yangtze River Delta. The financing supported GenFleet's strategy of exploring novel targets in oncology and immunology based on deep disease biology understanding, molecule design, and clinical pharmacology expertise. China eCapital served as the sole financial advisor. Post-Series B, GenFleet continued raising capital, including a Series B+ extension led by Northern Light Venture Capital with HM Capital, Linden Asset Group, Shanjin Capital, and existing investors CDH and Panlin, to accelerate global multi-center clinical development across China, America, and Australia. In December 2021, it completed a $75M (~500M RMB) Series C led by Huagai Capital with new investors like Suxin Venture Capital, Cherami Investment Group, ABC International, DYEE Capital, Qiaojing Eastern Investment, Baidu Venture, and Wenzhou Capital, aiming to push more programs into late-stage trials and commercialization within 3-5 years.
Nov-18Series ASinopharm Capital; Highlight Capital; CSPC Pharma Group; TF Capital; Ally Bridge Group$17M-GenFleet Therapeutics closed its Series A financing of 120 million yuan on November 30, 2018, led by Ally Bridge Group with participation from Sinopharm Capital and CSPC Pharma, and joined by prior angel investors including Highlight Capital, Hidragon Capital, and TF Capital. Proceeds will fund clinical development of immune-oncology therapeutics, particularly the IND application for its first innovative drug and subsequent clinical processes.
Apr-18SeedHighlight Capital$16M-GenFleet Therapeutics is a clinical-stage biotechnology company founded in 2017, focused on cutting-edge therapies in oncology and immunology with a pipeline of over 10 product candidates including both small molecules and biologics. The company received early-stage financing from Highlight Capital in 2017, approximately $14 million according to available reports. GenFleet subsequently completed a Series A round of $17.4 million led by Ally Bridge Group in 2019, followed by a Series B round of $57.7 million in early 2020 co-led by CDH Investments and Shenzhen Capital Group, and a Series C round of $75 million in December 2021 led by Huagai Capital. The company achieved a significant milestone by listing on the Hong Kong Stock Exchange in September 2025, raising gross proceeds of $233 million, and became the first biotech to list under Chapter 18A with a commercially launched product (fulzerasib) and established licensing revenue at the time of IPO.

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About GenFleet Therapeutics

When was GenFleet Therapeutics founded?GenFleet Therapeutics was founded in 2017.
Where is GenFleet Therapeutics headquartered?GenFleet Therapeutics is headquartered in China.
How many employees does GenFleet Therapeutics have?As of today, GenFleet Therapeutics has over 90 employees.
Is GenFleet Therapeutics publicly listed?Yes, GenFleet Therapeutics is a public company listed on HKEX.
What is the stock symbol of GenFleet Therapeutics?GenFleet Therapeutics trades under 02595 ticker.
When did GenFleet Therapeutics go public?GenFleet Therapeutics went public in 2025.
Who are competitors of GenFleet Therapeutics?GenFleet Therapeutics main competitors include Verastem, Star Lake Bioscience, Viyash Scientific, Basilea Pharmaceutica, Janux Therapeutics, Symbiotec Pharmalab, CStone Pharmaceuticals, TOWA Pharmaceutical, Oscotec, Freenome.
What is the current market cap of GenFleet Therapeutics?GenFleet Therapeutics' current market cap is $1.1B.
What is the current revenue of GenFleet Therapeutics?GenFleet Therapeutics' last 12 months revenue is $17M.
What is the current revenue growth of GenFleet Therapeutics?GenFleet Therapeutics revenue growth (NTM/LTM) is 115%.
What is the current EV/Revenue multiple of GenFleet Therapeutics?Current revenue multiple of GenFleet Therapeutics is 48.1x.
Is GenFleet Therapeutics profitable?No, GenFleet Therapeutics is not profitable.
What is the current EBITDA of GenFleet Therapeutics?GenFleet Therapeutics has negative EBITDA and is not profitable.
What is GenFleet Therapeutics' EBITDA margin?GenFleet Therapeutics' last 12 months EBITDA margin is (676%).
What is the current EV/EBITDA multiple of GenFleet Therapeutics?Current EBITDA multiple of GenFleet Therapeutics is (7.1x).
What is the current FCF of GenFleet Therapeutics?GenFleet Therapeutics' last 12 months FCF is ($49M).
What is GenFleet Therapeutics' FCF margin?GenFleet Therapeutics' last 12 months FCF margin is (290%).
What is the current EV/FCF multiple of GenFleet Therapeutics?Current FCF multiple of GenFleet Therapeutics is (16.6x).
How many companies GenFleet Therapeutics has acquired to date?GenFleet Therapeutics hasn't acquired any companies yet (or none have been disclosed publicly).
In how many companies GenFleet Therapeutics has invested to date?GenFleet Therapeutics hasn't invested in any companies yet (or none have been disclosed publicly).

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