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- Definium Therapeutics
Definium Therapeutics Valuation Multiples
Definium Therapeutics is valued at $4.5B as of November 2026. In the last 12 months, Definium Therapeutics EBITDA was ($268M).
Definium Therapeutics Overview
About Definium Therapeutics
Definium Therapeutics Inc is developing inventive, next-generation therapeutics intended to solve the underlying causes of psychiatric and neurological disorders and offer patients long-term remission rather than transient symptom reduction. Its late-stage pipeline includes four Phase 3 trials-two each for GAD and MDD-anchored by its candidate, DT120 ODT, which has received FDA Breakthrough Therapy Designation for GAD. In parallel, the Company is advancing its commercial and operational readiness to support a best-in-class care model and prepare for the potential launch of DT120 ODT, if approved and marketed. The company also continues to advance its early-stage pipeline, having dosed the first patient in a Phase 2a study of DT4023 in adults with autism spectrum disorder (ASD).
Founded
2010
HQ
Employees
74
Website
Sectors
Financials (LTM)
EV
$3.4B
Valuation Multiples
Start free trialDefinium Therapeutics Financials
Definium Therapeutics reported last 12-month revenue of - and negative EBITDA of ($268M).
In the same LTM period, Definium Therapeutics generated - in gross profit, ($268M) in EBITDA losses, and had net loss of ($349M).
Revenue (LTM)
Definium Therapeutics P&L
In the most recent fiscal year, Definium Therapeutics reported revenue of - and EBITDA of ($189M).
Definium Therapeutics is unprofitable as of last fiscal year, with gross margin of -, EBITDA margin of -, and net margin of -.
Financial data powered by Morningstar, Inc.
Definium Therapeutics Stock Performance
Definium Therapeutics has current market cap of $4.5B, and enterprise value of $3.4B.
Market Cap Evolution
Definium Therapeutics' stock price is $33.27.
Definium Therapeutics share price decreased by 8.4% in the last 30 days, and increased by 163.0% in the last year.
Definium Therapeutics has an EPS (earnings per share) of $-1.37.
| EV | Market Cap | Price 1D | Price 1M | Price 3M | Price 12M | EPS |
|---|---|---|---|---|---|---|
| $3.4B | $4.5B | 0.1% | -8.4% | -16.2% | 163.0% | $-1.37 |
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Start Free TrialDefinium Therapeutics Valuation Multiples
Definium Therapeutics trades at (12.8x) EV/EBITDA.
Definium Therapeutics Financial Valuation Multiples
As of November 8, 2026, Definium Therapeutics has market cap of $4.5B and EV of $3.4B.
Definium Therapeutics has a P/E ratio of (12.8x).
Multiples above and below 250x are considered non-meaningful (n/m). Valuation data powered by FactSet, Inc. and Morningstar, Inc.
Verified Definium Therapeutics Valuation Multiples
Access all public comps and forward-looking valuation multiples like EV/Revenue in 2027, based on consensus analyst estimates. Powered by FactSet and Morningstar.


Definium Therapeutics Margins & Growth Rates
Definium Therapeutics grew EBITDA by 51% in the last fiscal year.
Definium Therapeutics Growth Rates
Data powered by FactSet, Inc. and Morningstar, Inc.
Definium Therapeutics Operational KPIs
Definium Therapeutics' revenue per employee in the last FY averaged $0.0M, while opex per employee averaged $2.2M for the same period.
Data powered by FactSet, Inc. and Morningstar, Inc.
Definium Therapeutics Competitors
Definium Therapeutics competitors include Emcure Pharmaceuticals, Yuhan, Camurus, Changchun High-Tech, GSK India, Ajanta Pharma, Legend Biotech, Hanmi Pharm, Aspen Pharmacare and Hikma Pharmaceuticals.
Most Definium Therapeutics public comparables operate across Biopharmaceuticals and BioTech.
| Last FY | EV/Revenue | EV/EBITDA | ||||||
|---|---|---|---|---|---|---|---|---|
| Revenue | EBITDA | Last FY | LTM | 2027E | Last FY | LTM | 2027E | |
| $969M | $194M | 4.8x | 4.3x | 23.9x | 21.3x | |||
| $1.6B | $221M | 2.7x | 2.6x | 20.0x | 29.1x | |||
| $231M | $91M | 17.3x | 14.1x | 44.0x | 33.2x | |||
| $1.8B | $113M | 2.5x | 2.6x | 39.3x | 17.2x | |||
| $405M | $151M | 10.6x | 9.9x | 28.6x | 28.8x | |||
| $575M | $161M | 7.5x | 6.8x | 26.9x | 25.0x | |||
| $1B | ($272M) | 3.8x | 2.8x | (14.2x) | 193.2x | |||
| $1.1B | $238M | 4.0x | 3.4x | 19.0x | 11.4x | |||
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Acquisitions by Definium Therapeutics
Definium Therapeutics has acquired 1 company to date.
Last acquisition by Definium Therapeutics was on February 18th 2021. Definium Therapeutics acquired HealthMode for $32M (EV/Revenue multiple available to Pro users).
Latest Acquisitions by Definium Therapeutics
| Description | HealthMode is a developer of AI-enabled digital measurement tools for clinical trials and healthcare. The Boston-based firm partners with pharmaceutical companies, academic medical centers, and startups to deliver precise phenotype analysis, eligibility screening, adverse event detection, and efficacy endpoints that integrate trial data with real-world evidence. |
| HQ Country | |
| HQ City | San Francisco, CA |
| Deal Date | 18 Feb 2021 |
| Valuation | $32M |
| EV/Revenue | |
| EV/EBITDA | |
This data is available for Pro users. Sign up to see all Definium Therapeutics acquisitions and their M&A valuation multiples. Start Free Trial | |
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Start Free TrialAbout Definium Therapeutics
| When was Definium Therapeutics founded? | Definium Therapeutics was founded in 2010. |
| Where is Definium Therapeutics headquartered? | Definium Therapeutics is headquartered in United States. |
| How many employees does Definium Therapeutics have? | As of today, Definium Therapeutics has over 74 employees. |
| Is Definium Therapeutics publicly listed? | Yes, Definium Therapeutics is a public company listed on Nasdaq. |
| What is the stock symbol of Definium Therapeutics? | Definium Therapeutics trades under DFTX ticker. |
| When did Definium Therapeutics go public? | Definium Therapeutics went public in 2020. |
| Who are competitors of Definium Therapeutics? | Definium Therapeutics main competitors include Emcure Pharmaceuticals, Yuhan, Camurus, Changchun High-Tech, GSK India, Ajanta Pharma, Legend Biotech, Hanmi Pharm, Aspen Pharmacare, Hikma Pharmaceuticals. |
| What is the current market cap of Definium Therapeutics? | Definium Therapeutics' current market cap is $4.5B. |
| Is Definium Therapeutics profitable? | No, Definium Therapeutics is not profitable. |
| What is the current EBITDA of Definium Therapeutics? | Definium Therapeutics has negative EBITDA and is not profitable. |
| What is the current EV/EBITDA multiple of Definium Therapeutics? | Current EBITDA multiple of Definium Therapeutics is (12.8x). |
| What is the current FCF of Definium Therapeutics? | Definium Therapeutics' last 12 months FCF is ($196M). |
| What is the current EV/FCF multiple of Definium Therapeutics? | Current FCF multiple of Definium Therapeutics is (17.5x). |
| How many companies Definium Therapeutics has acquired to date? | As of November 2026, Definium Therapeutics has acquired 1 company. |
| What was the largest acquisition by Definium Therapeutics? | $32M acquisition of HealthMode on 18th February 2021 was the largest M&A Definium Therapeutics has done to date. |
| What companies Definium Therapeutics acquired? | Definium Therapeutics acquired HealthMode. |
| In how many companies Definium Therapeutics has invested to date? | Definium Therapeutics hasn't invested in any companies yet (or none have been disclosed publicly). |
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