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Xilio Therapeutics Inc is a clinical-stage biotechnology company discovering and developing tumor-activated immuno-oncology (I-O) therapies with the goal of significantly improving outcomes for people living with cancer without the systemic side effects of current I-O treatments. The company is using its proprietary platform to advance a pipeline of novel, tumor-activated clinical and preclinical I-O molecules that are designed to optimize the therapeutic index by localizing anti-tumor activity within the tumor microenvironment, including tumor-activated cytokines and antibodies (including bispecifics) and immune cell engagers (including tumor-activated cell engagers and tumor-activated effector-enhanced cell engagers).
2020
64
LTM Revenue $17.9M
LTM EBITDA -$42.9M
-$10.2M
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Xilio Therapeutics has a last 12-month revenue of $17.9M and a last 12-month EBITDA of -$42.9M.
In the most recent fiscal year, Xilio Therapeutics achieved revenue of $6.3M and an EBITDA of -$58.0M.
Xilio Therapeutics expects next 12-month revenue of XXX and NTM EBITDA of XXX
See Xilio Therapeutics valuation multiples based on analyst estimates| FY 2023 | FY 2024 | FY 2025 | LTM | NTM | |
|---|---|---|---|---|---|
| Revenue | n/a | $6.3M | XXX | XXX | XXX |
| Gross Profit | n/a | n/a | XXX | XXX | XXX |
| Gross Margin | NaN% | NaN% | XXX | XXX | XXX |
| EBITDA | -$77.2M | -$58.0M | XXX | XXX | XXX |
| EBITDA Margin | -Infinity% | -914% | XXX | XXX | XXX |
| Net Profit | -$88.2M | -$76.4M | XXX | XXX | XXX |
| Net Margin | -Infinity% | -1204% | XXX | XXX | XXX |
| Net Debt | n/a | n/a | XXX | XXX | XXX |
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As of April 15, 2025, Xilio Therapeutics's stock price is $1.
Xilio Therapeutics has current market cap of $37.0M, and EV of -$10.2M.
See Xilio Therapeutics trading valuation data| EV | Market Cap | Price 1D | Price 1M | Price 3M | Price 12M | EPS |
|---|---|---|---|---|---|---|
| -$10.2M | $37.0M | XXX | XXX | XXX | XXX | $-0.88 |
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Sign UpAs of April 15, 2025, Xilio Therapeutics has market cap of $37.0M and EV of -$10.2M.
Xilio Therapeutics's trades at -0.6x LTM EV/Revenue multiple, and 0.2x LTM EBITDA.
Analysts estimate Xilio Therapeutics's 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX
See valuation multiples for Xilio Therapeutics and 10K+ public comps| FY 2024 | FY 2025E | FY 2026E | FY 2027E | |
|---|---|---|---|---|
| EV | -$10.2M | XXX | XXX | XXX |
| EV/Revenue | -1.6x | XXX | XXX | XXX |
| EV/EBITDA | 0.2x | XXX | XXX | XXX |
| P/E | -0.6x | XXX | XXX | XXX |
| P/E/Growth | n/a | XXX | XXX | XXX |
| EV/FCF | 0.6x | XXX | XXX | XXX |
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Access all public comps and forward-looking valuation multiples like EV/Revenue in 2025, based on equity research analyst estimates.
Sign UpXilio Therapeutics's NTM/LTM revenue growth is 181%
Xilio Therapeutics's revenue per employee for the last fiscal year averaged $0.1M, while opex per employee averaged $1.0M for the same period.
Over next 12 months, Xilio Therapeutics's ratio of sales and marketing spend to revenue is estimated to be XXX , while its R&D spend to revenue to be XXX .
Analysts estimate Xilio Therapeutics's 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX
See operational valuation multiples for Xilio Therapeutics and other 10K+ public comps| FY 2024 | NTM | FY 2025E | FY 2026E | FY 2027E | |
|---|---|---|---|---|---|
| Revenue Growth | Infinity% | XXX | XXX | XXX | XXX |
| EBITDA Margin | -914% | XXX | XXX | XXX | XXX |
| EBITDA Growth | -25% | XXX | XXX | XXX | XXX |
| Rule of 40 (SaaS-only) | -734% | XXX | XXX | XXX | XXX |
| Revenue per Employee | $0.1M | XXX | XXX | XXX | XXX |
| Opex per Employee | $1.0M | XXX | XXX | XXX | XXX |
| S&M Expenses to Revenue | n/a | XXX | XXX | XXX | XXX |
| G&A Expenses to Revenue | 391% | XXX | XXX | XXX | XXX |
| R&D Expenses to Revenue | 650% | XXX | XXX | XXX | XXX |
| Opex to Revenue | 1040% | XXX | XXX | XXX | XXX |
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Benchmark public comps and private revenue and EBITDA valuation multiples across GRC software, cloud infrastructure, DevOps, online marketplaces and so much more!
| EV/Revenue | EV/EBITDA | |||||
|---|---|---|---|---|---|---|
| 2025E | 2026E | 2027E | 2025E | 2026E | 2027E | |
| Julphar | XXX | XXX | XXX | XXX | XXX | XXX |
| Benevolent AI | XXX | XXX | XXX | XXX | XXX | XXX |
| Galapagos | XXX | XXX | XXX | XXX | XXX | XXX |
| Pharming | XXX | XXX | XXX | XXX | XXX | XXX |
| Vivoryon Therapeutics | XXX | XXX | XXX | XXX | XXX | XXX |
| XXXXXXXX | XXX | XXX | XXX | XXX | XXX | XXX |
| XXXXXXXX | XXX | XXX | XXX | XXX | XXX | XXX |
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Xilio Therapeutics acquired XXX companies to date.
Last acquisition by Xilio Therapeutics was XXXXXXXX, XXXXX XXXXX XXXXXX . Xilio Therapeutics acquired XXXXXXXX for XXX (EV/Revenue multiple of XXX ).
See M&A valuation multiples| Acquired Company | EV | EV/Revenue | EV/EBITDA |
|---|---|---|---|
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
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Sign Up| When was Xilio Therapeutics founded? | Xilio Therapeutics was founded in 2020. |
| Where is Xilio Therapeutics headquartered? | Xilio Therapeutics is headquartered in United States of America. |
| How many employees does Xilio Therapeutics have? | As of today, Xilio Therapeutics has 64 employees. |
| Who is the CEO of Xilio Therapeutics? | Xilio Therapeutics's CEO is Dr. Rene Russo, Pharm.D.. |
| Is Xilio Therapeutics publicy listed? | Yes, Xilio Therapeutics is a public company listed on NAS. |
| What is the stock symbol of Xilio Therapeutics? | Xilio Therapeutics trades under XLO ticker. |
| When did Xilio Therapeutics go public? | Xilio Therapeutics went public in 2021. |
| Who are competitors of Xilio Therapeutics? | Similar companies to Xilio Therapeutics include e.g. Julphar, Benevolent AI, Galapagos, Pharming. |
| What is the current market cap of Xilio Therapeutics? | Xilio Therapeutics's current market cap is $37.0M |
| What is the current revenue of Xilio Therapeutics? | Xilio Therapeutics's last 12-month revenue is $17.9M. |
| What is the current EBITDA of Xilio Therapeutics? | Xilio Therapeutics's last 12-month EBITDA is -$42.9M. |
| What is the current EV/Revenue multiple of Xilio Therapeutics? | Current revenue multiple of Xilio Therapeutics is -0.6x. |
| What is the current EV/EBITDA multiple of Xilio Therapeutics? | Current EBITDA multiple of Xilio Therapeutics is 0.2x. |
| Is Xilio Therapeutics profitable? | Yes, Xilio Therapeutics is EBITDA-positive (as of the last 12 months). |
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