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Lyell Immunopharma Valuation Multiples

Discover revenue and EBITDA valuation multiples for Lyell Immunopharma and similar public comparables like Benevolent AI, Pharming, and Julphar.

Lyell Immunopharma Overview

About Lyell Immunopharma

Lyell Immunopharma Inc is a clinical-stage cell therapy company. It has a pipeline of product candidates for patients with solid tumors utilizing ex vivo genetic and epigenetic T-cell reprogramming technologies. The company's product pipeline includes, LYL797, LYL119, LYL845 among others.


Founded

2018

HQ

United States of America
Employees

300

Website

lyell.com

Financials

LTM Revenue $46K

LTM EBITDA -$254M

EV

$2.3B

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Lyell Immunopharma Financials

Lyell Immunopharma has a last 12-month revenue (LTM) of $46K and a last 12-month EBITDA of -$254M.

In the most recent fiscal year, Lyell Immunopharma achieved revenue of $0.1M and an EBITDA of -$201M.

Lyell Immunopharma expects next 12-month revenue of  XXX    and NTM EBITDA of  XXX

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Lyell Immunopharma P&L

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue $46K XXX $0.1M XXX XXX XXX
Gross Profit $46K XXX n/a XXX XXX XXX
Gross Margin 100% XXX n/a XXX XXX XXX
EBITDA -$254M XXX -$201M XXX XXX XXX
EBITDA Margin -550362% XXX -328923% XXX XXX XXX
EBIT -$274M XXX -$220M XXX XXX XXX
EBIT Margin -594743% XXX -361105% XXX XXX XXX
Net Profit -$286M XXX -$343M XXX XXX XXX
Net Margin -620240% XXX -562285% XXX XXX XXX
Net Debt XXX XXX n/a XXX XXX XXX

Financial data powered by Morningstar, Inc.

Lyell Immunopharma Stock Performance

As of May 30, 2025, Lyell Immunopharma's stock price is $9.

Lyell Immunopharma has current market cap of $2.5B, and EV of $2.3B.

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Lyell Immunopharma Stock Data

EV Market Cap Price 1D Price 1M Price 3M Price 12M EPS
$2.3B $2.5B XXX XXX XXX XXX $-1.06

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Lyell Immunopharma Valuation Multiples

As of May 30, 2025, Lyell Immunopharma has market cap of $2.5B and EV of $2.3B.

Lyell Immunopharma's trades at 37607.7x EV/Revenue multiple, and -11.4x EV/EBITDA.

Equity research analysts estimate Lyell Immunopharma's 2025E EV/Revenue multiple at  XXX and 2025E EV/EBITDA multiple at  XXX

Lyell Immunopharma has a P/E ratio of -8.9x.

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Lyell Immunopharma Financial Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Market cap (current) $2.5B XXX $2.5B XXX XXX XXX
EV (current) $2.3B XXX $2.3B XXX XXX XXX
EV/Revenue 49755.5x XXX 37607.7x XXX XXX XXX
EV/EBITDA -9.0x XXX -11.4x XXX XXX XXX
EV/EBIT -8.4x XXX -10.4x XXX XXX XXX
EV/Gross Profit 49755.5x XXX n/a XXX XXX XXX
P/E -8.9x XXX -7.4x XXX XXX XXX
EV/FCF -15.8x XXX -14.1x XXX XXX XXX

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Lyell Immunopharma Margins & Growth Rates

Lyell Immunopharma's last 12 month revenue growth is -50%

Lyell Immunopharma's revenue per employee in the last FY averaged $0K, while opex per employee averaged $0.7M for the same period.

Lyell Immunopharma's rule of 40 is -174479% (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Lyell Immunopharma's rule of X is -550486% (created by Bessemer, rule of X is another metric relevant for SaaS companies only, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

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Lyell Immunopharma Operational Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue Growth -50% XXX -42% XXX XXX XXX
EBITDA Margin -550362% XXX -328923% XXX XXX XXX
EBITDA Growth -19% XXX n/a XXX XXX XXX
Rule of 40 -174479% XXX -328973% XXX XXX XXX
Bessemer Rule of X XXX XXX -550486% XXX XXX XXX
Revenue per Employee XXX XXX $0K XXX XXX XXX
Opex per Employee XXX XXX $0.7M XXX XXX XXX
S&M Expenses to Revenue XXX XXX n/a XXX XXX XXX
G&A Expenses to Revenue XXX XXX n/a XXX XXX XXX
R&D Expenses to Revenue XXX XXX 281316% XXX XXX XXX
Opex to Revenue XXX XXX 361205% XXX XXX XXX

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Lyell Immunopharma Public Comps

See public comps and valuation multiples for Drug Development & Therapeutics and Vaccines & Immunotherapies comps
EV/Revenue EV/EBITDA
2025E 2026E 2027E 2025E 2026E 2027E
Julphar XXX XXX XXX XXX XXX XXX
Benevolent AI XXX XXX XXX XXX XXX XXX
Galapagos XXX XXX XXX XXX XXX XXX
Pharming XXX XXX XXX XXX XXX XXX
Vivoryon Therapeutics XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX

Valuation data powered by FactSet, Inc.

Lyell Immunopharma M&A and Investment Activity

Lyell Immunopharma acquired  XXX companies to date.

Last acquisition by Lyell Immunopharma was  XXXXXXXX, XXXXX XXXXX XXXXXX . Lyell Immunopharma acquired  XXXXXXXX for  XXX (EV/Revenue multiple of  XXX ).

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Latest Acquisitions by Lyell Immunopharma

Acquired Company EV EV/Revenue EV/EBITDA
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX

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About Lyell Immunopharma

When was Lyell Immunopharma founded? Lyell Immunopharma was founded in 2018.
Where is Lyell Immunopharma headquartered? Lyell Immunopharma is headquartered in United States of America.
How many employees does Lyell Immunopharma have? As of today, Lyell Immunopharma has 300 employees.
Who is the CEO of Lyell Immunopharma? Lyell Immunopharma's CEO is Dr. Lynn Seely,M.D..
Is Lyell Immunopharma publicy listed? Yes, Lyell Immunopharma is a public company listed on NAS.
What is the stock symbol of Lyell Immunopharma? Lyell Immunopharma trades under LYEL ticker.
When did Lyell Immunopharma go public? Lyell Immunopharma went public in 2021.
Who are competitors of Lyell Immunopharma? Similar companies to Lyell Immunopharma include e.g. Julphar, Benevolent AI, Galapagos, Pharming.
What is the current market cap of Lyell Immunopharma? Lyell Immunopharma's current market cap is $2.5B
What is the current revenue of Lyell Immunopharma? Lyell Immunopharma's last 12 months revenue is $46K.
What is the current revenue growth of Lyell Immunopharma? Lyell Immunopharma revenue growth (NTM/LTM) is -50%.
What is the current EV/Revenue multiple of Lyell Immunopharma? Current revenue multiple of Lyell Immunopharma is 49755.5x.
Is Lyell Immunopharma profitable? Yes, Lyell Immunopharma is EBITDA-positive (as of the last 12 months).
What is the current EBITDA of Lyell Immunopharma? Lyell Immunopharma's last 12 months EBITDA is -$254M.
What is Lyell Immunopharma's EBITDA margin? Lyell Immunopharma's last 12 months EBITDA margin is -550362%.
What is the current EV/EBITDA multiple of Lyell Immunopharma? Current EBITDA multiple of Lyell Immunopharma is -9.0x.
What is the current FCF of Lyell Immunopharma? Lyell Immunopharma's last 12 months FCF is -$145M.
What is Lyell Immunopharma's FCF margin? Lyell Immunopharma's last 12 months FCF margin is -314985%.
What is the current EV/FCF multiple of Lyell Immunopharma? Current FCF multiple of Lyell Immunopharma is -15.8x.

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