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Lyell Immunopharma Valuation Multiples
Discover revenue and EBITDA valuation multiples for Lyell Immunopharma and similar public comparables like Kamada, Kyverna Therapeutics, GC Biopharma, Climb Bio and more.
Lyell Immunopharma Overview
About Lyell Immunopharma
Lyell Immunopharma Inc is a clinical-stage cell therapy company. It has a pipeline of product candidates for patients with solid tumors utilizing ex vivo genetic and epigenetic T-cell reprogramming technologies. The company's product pipeline includes, LYL797, LYL119, LYL845 among others.
Founded
2018
HQ

Employees
300
Website
Sectors
Financials (LTM)
EV
$228M
Lyell Immunopharma Financials
Lyell Immunopharma reported last 12-month revenue of $32K and negative EBITDA of ($248M).
In the same LTM period, Lyell Immunopharma generated ($248M) in EBITDA losses and had net loss of ($261M).
Revenue (LTM)
Lyell Immunopharma P&L
In the most recent fiscal year, Lyell Immunopharma reported revenue of $36K and EBITDA of ($190M).
Lyell Immunopharma expects next 12-month revenue of XXX and NTM EBITDA of XXX
| LTM | NTM | Last FY | FY 2026 | FY 2027 | FY 2028 | |
|---|---|---|---|---|---|---|
| Revenue | $32K | XXX | $36K | XXX | XXX | XXX |
| EBITDA | ($248M) | XXX | ($190M) | XXX | XXX | XXX |
| EBITDA Margin | (784689%) | XXX | (528028%) | XXX | XXX | XXX |
| EBIT Margin | (818055%) | XXX | (560081%) | XXX | XXX | XXX |
| Net Profit | ($261M) | XXX | ($274M) | XXX | XXX | XXX |
| Net Margin | (824611%) | XXX | (762356%) | XXX | XXX | XXX |
Financial data powered by Morningstar, Inc.
Lyell Immunopharma Stock Performance
Lyell Immunopharma has current market cap of $503M, and enterprise value of $228M.
Market Cap Evolution
Lyell Immunopharma's stock price is $23.70.
| EV | Market Cap | Price 1D | Price 1M | Price 3M | Price 12M | EPS |
|---|---|---|---|---|---|---|
| $228M | $503M | 0.0% | XXX | XXX | XXX | $-12.92 |
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Start Free TrialLyell Immunopharma Valuation Multiples
Lyell Immunopharma trades at 7210.5x EV/Revenue multiple, and (0.9x) EV/EBITDA.
EV / Revenue (LTM)
Lyell Immunopharma Financial Valuation Multiples
As of March 18, 2026, Lyell Immunopharma has market cap of $503M and EV of $228M.
Equity research analysts estimate Lyell Immunopharma's 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX
Lyell Immunopharma has a P/E ratio of (1.9x).
| LTM | NTM | Last FY | FY 2026 | FY 2027 | FY 2028 | |
|---|---|---|---|---|---|---|
| Market cap (current) | $503M | XXX | $503M | XXX | XXX | XXX |
| EV (current) | $228M | XXX | $228M | XXX | XXX | XXX |
| EV/Revenue | 7210.5x | XXX | 6337.3x | XXX | XXX | XXX |
| EV/EBITDA | (0.9x) | XXX | (1.2x) | XXX | XXX | XXX |
| EV/EBIT | (0.9x) | XXX | (1.1x) | XXX | XXX | XXX |
| P/E | (1.9x) | XXX | (1.8x) | XXX | XXX | XXX |
| EV/FCF | — | XXX | (1.5x) | XXX | XXX | XXX |
Valuation data powered by FactSet, Inc. and Morningstar, Inc.
Verified Lyell Immunopharma Valuation Multiples
Access all public comps and forward-looking valuation multiples like EV/Revenue in 2027, based on consensus analyst estimates. Powered by FactSet and Morningstar.


Lyell Immunopharma Margins & Growth Rates
Lyell Immunopharma's revenue in the last 12 month grew by 1614%.
Lyell Immunopharma's revenue per employee in the last FY averaged $0.0M.
Lyell Immunopharma's rule of 40 is (783076%) (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).
Lyell Immunopharma's rule of X is (780655%) (created by Bessemer, rule of X is another metric to measure SaaS companies, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).
Lyell Immunopharma Operational Valuation Multiples
| LTM | NTM | Last FY | FY 2026 | FY 2027 | FY 2028 | |
|---|---|---|---|---|---|---|
| Revenue Growth | 1614% | XXX | (57%) | XXX | XXX | XXX |
| EBITDA Margin | (784689%) | XXX | (528028%) | XXX | XXX | XXX |
| EBITDA Growth | (7%) | XXX | 12% | XXX | XXX | XXX |
| Rule of 40 | — | XXX | (783076%) | XXX | XXX | XXX |
| Bessemer Rule of X | — | XXX | (780655%) | XXX | XXX | XXX |
| Revenue per Employee | — | XXX | $0.0M | XXX | XXX | XXX |
| G&A Expenses to Revenue | 144232% | XXX | 125375% | XXX | XXX | XXX |
| R&D Expenses to Revenue | 508015% | XXX | 440764% | XXX | XXX | XXX |
| Opex to Revenue | — | XXX | 560181% | XXX | XXX | XXX |
Valuation data powered by FactSet, Inc. and Morningstar, Inc.
Lyell Immunopharma Public Comps
See public comps and valuation multiples for other Biopharmaceuticals comps.
| EV/Revenue | EV/EBITDA | |||||
|---|---|---|---|---|---|---|
| LTM | 2026E | 2027E | LTM | 2026E | 2027E | |
| Kamada | XXX | XXX | XXX | XXX | XXX | XXX |
| Kyverna Therapeutics | XXX | XXX | XXX | XXX | XXX | XXX |
| GC Biopharma | XXX | XXX | XXX | XXX | XXX | XXX |
| Climb Bio | XXX | XXX | XXX | XXX | XXX | XXX |
| Genfit | XXX | XXX | XXX | XXX | XXX | XXX |
| XXXXXXXX | XXX | XXX | XXX | XXX | XXX | XXX |
| XXXXXXXX | XXX | XXX | XXX | XXX | XXX | XXX |
Valuation data powered by FactSet, Inc.
Lyell Immunopharma M&A Activity
Lyell Immunopharma acquired XXX companies to date.
Last acquisition by Lyell Immunopharma was on XXXXXXXX, XXXXX. Lyell Immunopharma acquired XXXXXXXX for XXX (EV/Revenue multiple of XXX).
Latest Acquisitions by Lyell Immunopharma
| Acquired Company | Valuation | EV/Revenue | EV/EBITDA |
|---|---|---|---|
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
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Start Free TrialLyell Immunopharma Investment Activity
Lyell Immunopharma invested in XXX companies to date.
Lyell Immunopharma made its latest investment on XXXXXXXX, XXXXX. Lyell Immunopharma invested in XXXXXXXX for XXX (EV/Revenue multiple of XXX).
Latest Investments by Lyell Immunopharma
| Company | Valuation | EV/Revenue | EV/EBITDA |
|---|---|---|---|
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
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Start Free TrialAbout Lyell Immunopharma
| When was Lyell Immunopharma founded? | Lyell Immunopharma was founded in 2018. |
| Where is Lyell Immunopharma headquartered? | Lyell Immunopharma is headquartered in United States. |
| How many employees does Lyell Immunopharma have? | As of today, Lyell Immunopharma has over 300 employees. |
| Who is the CEO of Lyell Immunopharma? | Lyell Immunopharma's CEO is Lynn Seely. |
| Is Lyell Immunopharma publicly listed? | Yes, Lyell Immunopharma is a public company listed on Nasdaq. |
| What is the stock symbol of Lyell Immunopharma? | Lyell Immunopharma trades under LYEL ticker. |
| When did Lyell Immunopharma go public? | Lyell Immunopharma went public in 2021. |
| Who are competitors of Lyell Immunopharma? | Lyell Immunopharma main competitors are Kamada, Kyverna Therapeutics, GC Biopharma, Climb Bio. |
| What is the current market cap of Lyell Immunopharma? | Lyell Immunopharma's current market cap is $503M. |
| What is the current revenue of Lyell Immunopharma? | Lyell Immunopharma's last 12 months revenue is $32K. |
| What is the current revenue growth of Lyell Immunopharma? | Lyell Immunopharma revenue growth (NTM/LTM) is 1614%. |
| What is the current EV/Revenue multiple of Lyell Immunopharma? | Current revenue multiple of Lyell Immunopharma is 7210.5x. |
| Is Lyell Immunopharma profitable? | No, Lyell Immunopharma is not profitable. |
| What is the current EBITDA of Lyell Immunopharma? | Lyell Immunopharma has negative EBITDA and is not profitable. |
| What is Lyell Immunopharma's EBITDA margin? | Lyell Immunopharma's last 12 months EBITDA margin is (784689%). |
| What is the current EV/EBITDA multiple of Lyell Immunopharma? | Current EBITDA multiple of Lyell Immunopharma is (0.9x). |
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