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Lyell Immunopharma Valuation Multiples

Discover revenue and EBITDA valuation multiples for Lyell Immunopharma and similar public comparables like Kamada, Kyverna Therapeutics, GC Biopharma, Climb Bio and more.

Lyell Immunopharma Overview

About Lyell Immunopharma

Lyell Immunopharma Inc is a clinical-stage cell therapy company. It has a pipeline of product candidates for patients with solid tumors utilizing ex vivo genetic and epigenetic T-cell reprogramming technologies. The company's product pipeline includes, LYL797, LYL119, LYL845 among others.


Founded

2018

HQ

United States

Employees

300

Website

lyell.com

Financials (LTM)

Revenue: $32K
EBITDA: ($248M)

EV

$228M

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Lyell Immunopharma Financials

Lyell Immunopharma reported last 12-month revenue of $32K and negative EBITDA of ($248M).

In the same LTM period, Lyell Immunopharma generated ($248M) in EBITDA losses and had net loss of ($261M).

Revenue (LTM)


Lyell Immunopharma P&L

In the most recent fiscal year, Lyell Immunopharma reported revenue of $36K and EBITDA of ($190M).

Lyell Immunopharma expects next 12-month revenue of XXX and NTM EBITDA of XXX

See Lyell Immunopharma forward-looking valuation multiples
LTMNTMLast FYFY 2026FY 2027FY 2028
Revenue$32KXXX$36KXXXXXXXXX
EBITDA($248M)XXX($190M)XXXXXXXXX
EBITDA Margin(784689%)XXX(528028%)XXXXXXXXX
EBIT Margin(818055%)XXX(560081%)XXXXXXXXX
Net Profit($261M)XXX($274M)XXXXXXXXX
Net Margin(824611%)XXX(762356%)XXXXXXXXX

Financial data powered by Morningstar, Inc.

Lyell Immunopharma Stock Performance

Lyell Immunopharma has current market cap of $503M, and enterprise value of $228M.

Market Cap Evolution


Lyell Immunopharma's stock price is $23.70.

See Lyell Immunopharma trading valuation data
EVMarket CapPrice 1DPrice 1MPrice 3MPrice 12MEPS
$228M$503M0.0%XXXXXXXXX$-12.92

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Lyell Immunopharma Valuation Multiples

Lyell Immunopharma trades at 7210.5x EV/Revenue multiple, and (0.9x) EV/EBITDA.

See valuation multiples for Lyell Immunopharma and 15K+ public comps

EV / Revenue (LTM)


Lyell Immunopharma Financial Valuation Multiples

As of March 18, 2026, Lyell Immunopharma has market cap of $503M and EV of $228M.

Equity research analysts estimate Lyell Immunopharma's 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX

Lyell Immunopharma has a P/E ratio of (1.9x).

LTMNTMLast FYFY 2026FY 2027FY 2028
Market cap (current)$503MXXX$503MXXXXXXXXX
EV (current)$228MXXX$228MXXXXXXXXX
EV/Revenue7210.5xXXX6337.3xXXXXXXXXX
EV/EBITDA(0.9x)XXX(1.2x)XXXXXXXXX
EV/EBIT(0.9x)XXX(1.1x)XXXXXXXXX
P/E(1.9x)XXX(1.8x)XXXXXXXXX
EV/FCF—XXX(1.5x)XXXXXXXXX

Valuation data powered by FactSet, Inc. and Morningstar, Inc.

Verified Lyell Immunopharma Valuation Multiples

Access all public comps and forward-looking valuation multiples like EV/Revenue in 2027, based on consensus analyst estimates. Powered by FactSet and Morningstar.

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Lyell Immunopharma Margins & Growth Rates

Lyell Immunopharma's revenue in the last 12 month grew by 1614%.

Lyell Immunopharma's revenue per employee in the last FY averaged $0.0M.

Lyell Immunopharma's rule of 40 is (783076%) (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Lyell Immunopharma's rule of X is (780655%) (created by Bessemer, rule of X is another metric to measure SaaS companies, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

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Lyell Immunopharma Operational Valuation Multiples

LTMNTMLast FYFY 2026FY 2027FY 2028
Revenue Growth1614%XXX(57%)XXXXXXXXX
EBITDA Margin(784689%)XXX(528028%)XXXXXXXXX
EBITDA Growth(7%)XXX12%XXXXXXXXX
Rule of 40—XXX(783076%)XXXXXXXXX
Bessemer Rule of X—XXX(780655%)XXXXXXXXX
Revenue per Employee—XXX$0.0MXXXXXXXXX
G&A Expenses to Revenue144232%XXX125375%XXXXXXXXX
R&D Expenses to Revenue508015%XXX440764%XXXXXXXXX
Opex to Revenue—XXX560181%XXXXXXXXX

Valuation data powered by FactSet, Inc. and Morningstar, Inc.

Valuation Multiples Across 230+ Verticals

Lyell Immunopharma Public Comps

See public comps and valuation multiples for other Biopharmaceuticals comps.

EV/RevenueEV/EBITDA
LTM2026E2027ELTM2026E2027E
KamadaXXXXXXXXXXXXXXXXXX
Kyverna TherapeuticsXXXXXXXXXXXXXXXXXX
GC BiopharmaXXXXXXXXXXXXXXXXXX
Climb BioXXXXXXXXXXXXXXXXXX
GenfitXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX

Valuation data powered by FactSet, Inc.

Lyell Immunopharma M&A Activity

Lyell Immunopharma acquired XXX companies to date.

Last acquisition by Lyell Immunopharma was on XXXXXXXX, XXXXX. Lyell Immunopharma acquired XXXXXXXX for XXX (EV/Revenue multiple of XXX).

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Latest Acquisitions by Lyell Immunopharma

Acquired CompanyValuationEV/RevenueEV/EBITDA
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX

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Lyell Immunopharma Investment Activity

Lyell Immunopharma invested in XXX companies to date.

Lyell Immunopharma made its latest investment on XXXXXXXX, XXXXX. Lyell Immunopharma invested in XXXXXXXX for XXX (EV/Revenue multiple of XXX).

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Latest Investments by Lyell Immunopharma

CompanyValuationEV/RevenueEV/EBITDA
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX

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About Lyell Immunopharma

When was Lyell Immunopharma founded?Lyell Immunopharma was founded in 2018.
Where is Lyell Immunopharma headquartered?Lyell Immunopharma is headquartered in United States.
How many employees does Lyell Immunopharma have?As of today, Lyell Immunopharma has over 300 employees.
Who is the CEO of Lyell Immunopharma?Lyell Immunopharma's CEO is Lynn Seely.
Is Lyell Immunopharma publicly listed?Yes, Lyell Immunopharma is a public company listed on Nasdaq.
What is the stock symbol of Lyell Immunopharma?Lyell Immunopharma trades under LYEL ticker.
When did Lyell Immunopharma go public?Lyell Immunopharma went public in 2021.
Who are competitors of Lyell Immunopharma?Lyell Immunopharma main competitors are Kamada, Kyverna Therapeutics, GC Biopharma, Climb Bio.
What is the current market cap of Lyell Immunopharma?Lyell Immunopharma's current market cap is $503M.
What is the current revenue of Lyell Immunopharma?Lyell Immunopharma's last 12 months revenue is $32K.
What is the current revenue growth of Lyell Immunopharma?Lyell Immunopharma revenue growth (NTM/LTM) is 1614%.
What is the current EV/Revenue multiple of Lyell Immunopharma?Current revenue multiple of Lyell Immunopharma is 7210.5x.
Is Lyell Immunopharma profitable?No, Lyell Immunopharma is not profitable.
What is the current EBITDA of Lyell Immunopharma?Lyell Immunopharma has negative EBITDA and is not profitable.
What is Lyell Immunopharma's EBITDA margin?Lyell Immunopharma's last 12 months EBITDA margin is (784689%).
What is the current EV/EBITDA multiple of Lyell Immunopharma?Current EBITDA multiple of Lyell Immunopharma is (0.9x).

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