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Immunome Valuation Multiples

Discover revenue and EBITDA valuation multiples for Immunome and similar public comparables like Mineralys Therapeutics, Hepalink, Disc Medicine, Lotus Pharmaceutical and more.

Immunome Overview

About Immunome

Immunome Inc is a biopharmaceutical company. It is engaged in utilizing a proprietary human memory B cell platform to discover and develop first-in-class antibody therapeutics designed to change the way diseases are currently being treated. The objective of the company is to establish a broad pipeline of preclinical and clinical assets which it can efficiently develop through successive value inflection points. The company's primary focus areas are oncology and infectious diseases, including COVID-19. It operates in the U.S. Its current pipelines comprise IM-1021, a fibroblast activation protein (FAP), and others.


Founded

2006

HQ

United States

Employees

118

Financials (LTM)

Revenue: $6M
EBITDA: ($235M)

EV

$2B

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Immunome Financials

Immunome reported last 12-month revenue of $6M and negative EBITDA of ($235M).

In the same LTM period, Immunome generated $6M in gross profit, ($235M) in EBITDA losses, and had net loss of ($224M).

Revenue (LTM)


Immunome P&L

In the most recent fiscal year, Immunome reported revenue of $7M and EBITDA of ($221M).

Immunome expects next 12-month revenue of XXX and NTM EBITDA of XXX

See Immunome forward-looking valuation multiples
LTMNTMLast FYFY 2026FY 2027FY 2028
Revenue$6MXXX$7MXXXXXXXXX
Gross Profit$6MXXX—XXXXXXXXX
Gross Margin97%XXX—XXXXXXXXX
EBITDA($235M)XXX($221M)XXXXXXXXX
EBITDA Margin(3657%)XXX(3186%)XXXXXXXXX
EBIT Margin(3686%)XXX(3229%)XXXXXXXXX
Net Profit($224M)XXX($212M)XXXXXXXXX
Net Margin(3489%)XXX(3060%)XXXXXXXXX

Financial data powered by Morningstar, Inc.

Immunome Stock Performance

Immunome has current market cap of $2B, and enterprise value of $2B.

Market Cap Evolution


Immunome's stock price is $20.95.

See Immunome trading valuation data
EVMarket CapPrice 1DPrice 1MPrice 3MPrice 12MEPS
$2B$2B0.0%XXXXXXXXX$-1.92

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Immunome Valuation Multiples

Immunome trades at 318.6x EV/Revenue multiple, and (8.7x) EV/EBITDA.

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EV / Revenue (LTM)


Immunome Financial Valuation Multiples

As of March 18, 2026, Immunome has market cap of $2B and EV of $2B.

Equity research analysts estimate Immunome's 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX

Immunome has a P/E ratio of (10.3x).

LTMNTMLast FYFY 2026FY 2027FY 2028
Market cap (current)$2BXXX$2BXXXXXXXXX
EV (current)$2BXXX$2BXXXXXXXXX
EV/Revenue318.6xXXX294.3xXXXXXXXXX
EV/EBITDA(8.7x)XXX(9.2x)XXXXXXXXX
EV/EBIT(8.6x)XXX(9.1x)XXXXXXXXX
EV/Gross Profit329.1xXXX—XXXXXXXXX
P/E(10.3x)XXX(10.9x)XXXXXXXXX
EV/FCF(9.7x)XXX(10.2x)XXXXXXXXX

Valuation data powered by FactSet, Inc. and Morningstar, Inc.

Verified Immunome Valuation Multiples

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Immunome Margins & Growth Rates

Immunome's revenue in the last 12 month grew by 225%.

Immunome's revenue per employee in the last FY averaged $0.1M.

Immunome's rule of 40 is (3432%) (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Immunome's rule of X is (3094%) (created by Bessemer, rule of X is another metric to measure SaaS companies, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

See operational valuation multiples for Immunome and other 15K+ public comps

Immunome Operational Valuation Multiples

LTMNTMLast FYFY 2026FY 2027FY 2028
Revenue Growth225%XXX(36%)XXXXXXXXX
EBITDA Margin(3657%)XXX(3186%)XXXXXXXXX
EBITDA Growth18%XXX26%XXXXXXXXX
Rule of 40—XXX(3432%)XXXXXXXXX
Bessemer Rule of X—XXX(3094%)XXXXXXXXX
Revenue per Employee—XXX$0.1MXXXXXXXXX
G&A Expenses to Revenue827%XXX631%XXXXXXXXX
R&D Expenses to Revenue2986%XXX2698%XXXXXXXXX
Opex to Revenue—XXX3329%XXXXXXXXX

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Valuation Multiples Across 230+ Verticals

Immunome Public Comps

See public comps and valuation multiples for other Biopharmaceuticals comps.

EV/RevenueEV/EBITDA
LTM2026E2027ELTM2026E2027E
Mineralys TherapeuticsXXXXXXXXXXXXXXXXXX
HepalinkXXXXXXXXXXXXXXXXXX
Disc MedicineXXXXXXXXXXXXXXXXXX
Lotus PharmaceuticalXXXXXXXXXXXXXXXXXX
Nanjing King-FriendXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX

Valuation data powered by FactSet, Inc.

Immunome M&A Activity

Immunome acquired XXX companies to date.

Last acquisition by Immunome was on XXXXXXXX, XXXXX. Immunome acquired XXXXXXXX for XXX (EV/Revenue multiple of XXX).

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Latest Acquisitions by Immunome

Acquired CompanyValuationEV/RevenueEV/EBITDA
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX

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Immunome Investment Activity

Immunome invested in XXX companies to date.

Immunome made its latest investment on XXXXXXXX, XXXXX. Immunome invested in XXXXXXXX for XXX (EV/Revenue multiple of XXX).

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Latest Investments by Immunome

CompanyValuationEV/RevenueEV/EBITDA
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX

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About Immunome

When was Immunome founded?Immunome was founded in 2006.
Where is Immunome headquartered?Immunome is headquartered in United States.
How many employees does Immunome have?As of today, Immunome has over 118 employees.
Who is the CEO of Immunome?Immunome's CEO is Clay B. Siegall.
Is Immunome publicly listed?Yes, Immunome is a public company listed on Nasdaq.
What is the stock symbol of Immunome?Immunome trades under IMNM ticker.
When did Immunome go public?Immunome went public in 2020.
Who are competitors of Immunome?Immunome main competitors are Mineralys Therapeutics, Hepalink, Disc Medicine, Lotus Pharmaceutical.
What is the current market cap of Immunome?Immunome's current market cap is $2B.
What is the current revenue of Immunome?Immunome's last 12 months revenue is $6M.
What is the current revenue growth of Immunome?Immunome revenue growth (NTM/LTM) is 225%.
What is the current EV/Revenue multiple of Immunome?Current revenue multiple of Immunome is 318.6x.
Is Immunome profitable?No, Immunome is not profitable.
What is the current EBITDA of Immunome?Immunome has negative EBITDA and is not profitable.
What is Immunome's EBITDA margin?Immunome's last 12 months EBITDA margin is (3657%).
What is the current EV/EBITDA multiple of Immunome?Current EBITDA multiple of Immunome is (8.7x).
What is the current FCF of Immunome?Immunome's last 12 months FCF is ($210M).
What is Immunome's FCF margin?Immunome's last 12 months FCF margin is (3272%).
What is the current EV/FCF multiple of Immunome?Current FCF multiple of Immunome is (9.7x).

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