Syncona - Public Comps and Valuation Multiples

Syncona Overview

About Syncona

Syncona Ltd is a closed-ended investment company in the United Kingdom. Its investment objective is to achieve superior long-term capital appreciation from its investments. The company invests in life science businesses (including private and quoted companies) and single or multi-asset projects (Life Science Investments).

Founded

2012

HQ

Employees

Website

synconaltd.com

Sectors

Private Equity
Asset Management

Financials

LTM Revenue $88.7M

LTM EBITDA $193M

EV

$814M

Valuation Multiples

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Syncona Financials

As of September 2025, Syncona reported last 12-month revenue of $88.7M and EBITDA of $193M.

In the same period, Syncona achieved -$191M in LTM net income.

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Syncona P&L

In the most recent fiscal year, Syncona reported revenue of -$91.1M.

Syncona expects next 12-month revenue of XXX and NTM EBITDA of XXX

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	LTM	NTM	Last FY	FY 2025	FY 2026	FY 2027
Revenue	$88.7M	XXX	-$91.1M	XXX	XXX	XXX
Gross Profit	n/a	XXX	n/a	XXX	XXX	XXX
Gross Margin	n/a	XXX	n/a	XXX	XXX	XXX
EBITDA	$193M	XXX	n/a	XXX	XXX	XXX
EBITDA Margin	218%	XXX	n/a	XXX	XXX	XXX
EBIT	$193M	XXX	n/a	XXX	XXX	XXX
EBIT Margin	218%	XXX	n/a	XXX	XXX	XXX
Net Profit	-$191M	XXX	-$191M	XXX	XXX	XXX
Net Margin	-215%	XXX	210%	XXX	XXX	XXX
Net Debt	XXX	XXX	n/a	XXX	XXX	XXX

Financial data powered by Morningstar, Inc.

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Financial performance metrics for Syncona including revenue, profitability, and margin analysis across different time periods. The company reported last twelve months revenue of $88.7M. EBITDA for the last twelve months was $193M.
Financial Metric	Last Twelve Months (LTM)	Next Twelve Months (NTM)	Most Recent Fiscal Year	Current Fiscal Year (2025)	Next Fiscal Year (2026)	Two Years Forward (2027)
Total Revenue	$88.7M	Analyst estimates available to subscribers	-$91.1M	Analyst estimates available to subscribers	Analyst estimates available to subscribers	Analyst estimates available to subscribers
Gross Profit	n/a	Analyst estimates available to subscribers	n/a	Analyst estimates available to subscribers	Analyst estimates available to subscribers	Analyst estimates available to subscribers
Gross Profit Margin	n/a	Analyst estimates available to subscribers	NaN% gross profit margin	Analyst estimates available to subscribers	Analyst estimates available to subscribers	Analyst estimates available to subscribers
EBITDA (Earnings Before Interest, Taxes, Depreciation, Amortization)	$193M	Analyst estimates available to subscribers	n/a	Analyst estimates available to subscribers	Analyst estimates available to subscribers	Analyst estimates available to subscribers
EBITDA Margin	217.9% EBITDA margin	Analyst estimates available to subscribers	NaN% EBITDA margin	Analyst estimates available to subscribers	Analyst estimates available to subscribers	Analyst estimates available to subscribers
EBIT (Earnings Before Interest and Taxes)	$193M	Analyst estimates available to subscribers	n/a	Analyst estimates available to subscribers	Analyst estimates available to subscribers	Analyst estimates available to subscribers
EBIT Margin	217.9% EBIT margin	Analyst estimates available to subscribers	n/a	Analyst estimates available to subscribers	Analyst estimates available to subscribers	Analyst estimates available to subscribers
Net Income (Net Profit)	-$191M	Analyst estimates available to subscribers	-$191M	Analyst estimates available to subscribers	Analyst estimates available to subscribers	Analyst estimates available to subscribers
Net Profit Margin	-215.2% net profit margin	Analyst estimates available to subscribers	209.6% net profit margin	Analyst estimates available to subscribers	Analyst estimates available to subscribers	Analyst estimates available to subscribers
Net Debt Position	Detailed debt information available to subscribers	Detailed debt information available to subscribers	n/a	Detailed debt information available to subscribers	Detailed debt information available to subscribers	Detailed debt information available to subscribers

Financial Performance Summary for Syncona

This financial data table provides comprehensive performance metrics for Syncona, a company based in United Kingdom of Great Britain and Northern Ireland. The metrics include revenue, profitability measures, and operational efficiency indicators across multiple time periods.

Recent Performance Highlights

Syncona generated $88.7M in revenue over the last twelve months.
The company achieved $193M in EBITDA over the last twelve months.
Net income over the last twelve months reached -$191M.

Fiscal Year Performance

In the most recent fiscal year, Syncona reported -$91.1M in total revenue.
The company maintained a gross profit margin of NaN% in the most recent fiscal year.
EBITDA margin for the fiscal year was NaN%.
Net profit margin reached 209.6% in the most recent fiscal year.

This financial data is sourced from Morningstar, Inc. and represents the most recent available information for Syncona. Forward-looking estimates and detailed financial projections are available through our premium subscription service.

Syncona Stock Performance

Syncona has current market cap of GBP 610M (or $814M), and EV of GBP 610M (or $814M).

Market Cap Evolution

Syncona Stock Data

As of October 17, 2025, Syncona's stock price is GBP 1 (or $1).

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EV	Market Cap	Price 1D	Price 1M	Price 3M	Price 12M	EPS
$814M	$814M	XXX	XXX	XXX	XXX	$-0.30

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Syncona Valuation Multiples

Syncona's trades at -17.3x EV/Revenue multiple, and n/a EV/EBITDA.

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Syncona Financial Valuation Multiples

As of October 17, 2025, Syncona has market cap of $814M and EV of $814M.

Equity research analysts estimate Syncona's 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX

Syncona has a P/E ratio of -4.3x.

	LTM	NTM	Last FY	FY 2025	FY 2026	FY 2027
Market cap (current)	$814M	XXX	$814M	XXX	XXX	XXX
EV (current)	$814M	XXX	$814M	XXX	XXX	XXX
EV/Revenue	9.2x	XXX	-17.3x	XXX	XXX	XXX
EV/EBITDA	4.2x	XXX	n/a	XXX	XXX	XXX
EV/EBIT	4.2x	XXX	n/a	XXX	XXX	XXX
EV/Gross Profit	n/a	XXX	n/a	XXX	XXX	XXX
P/E	-4.3x	XXX	-5.7x	XXX	XXX	XXX
EV/FCF	55.5x	XXX	16.0x	XXX	XXX	XXX

Valuation data powered by FactSet, Inc. and Morningstar, Inc.

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Syncona Margins & Growth Rates

Syncona's revenue per employee in the last FY averaged -$2.5M, while opex per employee averaged $2.7M for the same period.

Syncona's rule of 40 is unknown (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Syncona's rule of X is unknown (created by Bessemer, rule of X is another metric relevant for SaaS companies only, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

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Syncona Operational Valuation Multiples

	LTM	NTM	Last FY	FY 2025	FY 2026	FY 2027
Revenue Growth	n/a	XXX	n/a	XXX	XXX	XXX
EBITDA Margin	218%	XXX	n/a	XXX	XXX	XXX
EBITDA Growth	n/a	XXX	n/a	XXX	XXX	XXX
Rule of 40	n/a	XXX	n/a	XXX	XXX	XXX
Bessemer Rule of X	XXX	XXX	n/a	XXX	XXX	XXX
Revenue per Employee	XXX	XXX	-$2.5M	XXX	XXX	XXX
Opex per Employee	XXX	XXX	$2.7M	XXX	XXX	XXX
S&M Expenses to Revenue	XXX	XXX	n/a	XXX	XXX	XXX
G&A Expenses to Revenue	XXX	XXX	n/a	XXX	XXX	XXX
R&D Expenses to Revenue	XXX	XXX	n/a	XXX	XXX	XXX
Opex to Revenue	XXX	XXX	-110%	XXX	XXX	XXX

Valuation data powered by FactSet, Inc. and Morningstar, Inc.

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