Syncona Valuation Multiples

Syncona is valued at $1B as of October 2026, a 16.0x revenue multiple. In the last 12 months, Syncona revenue was $65M.

Syncona Overview

About Syncona

Syncona Ltd is a closed-ended investment company in the United Kingdom. Its investment objective is to achieve superior long-term capital appreciation from its investments. The company invests in life science businesses (including private and quoted companies) and single or multi-asset projects (Life Science Investments).


Founded

2012

HQ

United Kingdom

Employees

37

Financials (LTM)

Revenue: $65M
Net Income: ($12M)

EV

$1B

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Syncona Financials

Syncona reported last 12-month revenue of $65M.

In the same LTM period, Syncona generated had net loss of ($12M).

Revenue (LTM)


Syncona P&L

In the most recent fiscal year, Syncona reported revenue of $76M and net income of ($12M).

Syncona is unprofitable as of last fiscal year, with net margin of (16%).

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LTMLast FY202320242025202620272028
Revenue$65M$76M$57M($48M)$65M
Net Profit($12M)($12M)($15M)($144M)($12M)
Net Margin(18%)(16%)(27%)302%(18%)

Financial data powered by Morningstar, Inc.

Syncona Stock Performance

Syncona has current market cap of $1B, and enterprise value of $1B.

Market Cap Evolution


Syncona's stock price is $1.72.

Syncona share price increased by 27.2% in the last year.

Syncona has an EPS (earnings per share) of $-0.02.

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EVMarket CapPrice 1DPrice 1MPrice 3MPrice 12MEPS
$1B$1B0.2%-20.2%27.2%$-0.02

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Syncona Valuation Multiples

Syncona trades at 16.0x EV/Revenue multiple.

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EV / Revenue (LTM)


Syncona Financial Valuation Multiples

As of October 20, 2026, Syncona has market cap of $1B and EV of $1B.

Syncona has a P/E ratio of (89.7x).

LTMLast FY202320242025202620272028
EV/Revenue16.0x13.8x18.4x(21.8x)16.0x
P/E(89.7x)(87.8x)(69.2x)(7.3x)(89.7x)
EV/FCF-33.0x50.4x20.3x27.1x

Multiples above and below 250x are considered non-meaningful (n/m). Valuation data powered by FactSet, Inc. and Morningstar, Inc.

Verified Syncona Valuation Multiples

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Syncona Margins & Growth Rates

In the most recent fiscal year, Syncona reported net margin of (16%).

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Syncona Margins

Last FY202420252026202720282029
Net Margin(16%)302%(18%)(18%)
FCF Margin42%(108%)59%48%

Syncona Growth Rates

23/2424/2525/2626/2727/2828/29
Revenue Growth(184%)(237%)0%
Net Profit Growth853%(92%)0%
FCF Growth149%(25%)(18%)

Data powered by FactSet, Inc. and Morningstar, Inc.

Syncona Operational KPIs

Syncona's revenue per employee in the last FY averaged $2.0M, while opex per employee averaged $2.4M for the same period.

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Last FY202320242025202620272028
Revenue per Employee$2.0M---
Opex per Employee$2.4M---
G&A Expenses to Revenue17%8%(9%)17%
Opex to Revenue116%127%(202%)139%

Data powered by FactSet, Inc. and Morningstar, Inc.

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Syncona Competitors

Syncona competitors include Amanat, Waha Capital, Retail Estates, Sagicor Group Jamaica, Hanwha Investment, Mercialys, FII CSHG Logistica, Oaktree Specialty Lending, BKI Investment and Arendals Fossekompani.

Most Syncona public comparables operate across PE & VC and Asset Management.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
Amanat$254M$103M4.2x-10.3x-
Waha Capital$67M-16.8x5.6x--
Retail Estates$182M$178M11.1x12.2x11.3x14.7x
Sagicor Group Jamaica$556M$153M1.9x-6.8x-
Hanwha Investment$362M-9.6x---
Mercialys$249M$123M10.4x12.1x21.0x14.7x
FII CSHG Logistica$61M-17.3x---
Oaktree Specialty Lending$198M-12.1x8.4x--

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Acquisitions by Syncona

Syncona has acquired 2 companies to date.

Last acquisition by Syncona was on November 22nd 2023. Syncona acquired Freeline for $28M (EV/Revenue multiple available to Pro users).

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Latest Acquisitions by Syncona

Freeline
AGTC
Description
Freeline is a London-based clinical-stage biotech company developing AAV gene therapies for rare liver disorders like hemophilia B. Its lead candidate, FLT201, entered Phase 1/2 trials in 2022 using a proprietary capsid for high liver tropism and sustained Factor IX expression at 50 percent normal levels. Freeline also advances programs for Fabry disease, with manufacturing in Stevenage, UK, and partnerships with Sarepta Therapeutics. Publicly traded until 2022 acquisition talks.
Applied Genetic Technologies Corporation is a clinical-stage biotechnology firm developing AAV-based gene therapies for retinal and neuromuscular diseases. Headquartered in Alachua, Florida, it advances programs like AGTC-501 for X-linked retinitis pigmentosa and rAAV2tYF-GRK1-RPGR for XLRP, conducting Phase 1/2 trials with FDA orphan drug designations.
HQ CountryUnited KingdomUnited States
HQ City
Stevenage
Alachua, FL
Deal Date22 Nov 202324 Oct 2022
Valuation$28M$24M
EV/Revenue
EV/EBITDA

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Investments by Syncona

Syncona has invested in 30 companies to date.

Latest investment by Syncona was on October 13th 2026. Syncona invested in Vision Robotics Technology in their Angel round.

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Latest Investments by Syncona

Vision Robotics Technology
Re-Aim Therapeutics
ALTx Therapeutics
Beacon Therapeutics
Description
Vision Robotics Technology is a Shenzhen-based technology company working on tactile perception and robot manipulation. Its work centers on giving robots a sense of touch so they can handle objects more dexterously. The company was founded in 2025.
Re-Aim Therapeutics is a UK-based biotechnology startup developing functional cures for T cell-mediated autoimmune diseases through selective depletion of pathogenic T-cell subsets. Its lead asset, REA-001, is a monoclonal antibody that targets type-17 T cells to reset immune response and support durable remission.
ALTx Therapeutics is a London biotechnology company developing small molecule cancer treatments aimed at the Alternative Lengthening of Telomeres pathway, a mechanism that roughly 10 to 15 per cent of tumours use to keep dividing. It was spun out of the Francis Crick Institute on the DNA repair and telomere research of Simon Boulton, who is founder and chief scientific officer, and targets brain, paediatric and rare cancers that depend on the pathway. The company is pre-clinical and is being built inside Syncona's Slingshot accelerator.
Beacon Therapeutics is a London-headquartered gene therapy company targeting inherited retinal diseases causing blindness. The firm advances GT005, an AAV-delivered therapy for wet AMD choroidal neovascularization, with Phase 2b trials ongoing in the United States and Europe following seed funding from Oxford Nanopore founders.
HQ CountryChinaUnited KingdomUnited KingdomUnited Kingdom
HQ City
Shenzhen
Oxford
London
London
Deal Date13 Oct 202617 May 20265 Feb 20268 Jan 2026
RoundAngelSeedSeedSeries C
Raisedundisclosed$10M$17M$75M
InvestorsHyundai; SynconaOxford Science Enterprises; SynconaCancer Research Horizons; The Francis Crick Institute; SynconaRetinal Degeneration Fund; Oxford Science Enterprises; Advent Life Sciences; Goldman Sachs; Forbion Capital Partners; Syncona
Valuationundisclosedundisclosedundisclosedundisclosed
EV/Revenue
EV/EBITDA

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About Syncona

When was Syncona founded?Syncona was founded in 2012.
Where is Syncona headquartered?Syncona is headquartered in United Kingdom.
How many employees does Syncona have?As of today, Syncona has over 37 employees.
Is Syncona publicly listed?Yes, Syncona is a public company listed on London Stock Exchange.
What is the stock symbol of Syncona?Syncona trades under SYNC ticker.
When did Syncona go public?Syncona went public in 2016.
Who are competitors of Syncona?Syncona main competitors include Amanat, Waha Capital, Retail Estates, Sagicor Group Jamaica, Hanwha Investment, Mercialys, FII CSHG Logistica, Oaktree Specialty Lending, BKI Investment, Arendals Fossekompani.
What is the current market cap of Syncona?Syncona's current market cap is $1B.
What is the current revenue of Syncona?Syncona's last 12 months revenue is $65M.
What is the current EV/Revenue multiple of Syncona?Current revenue multiple of Syncona is 16.0x.
Is Syncona profitable?No, Syncona is not profitable.
What is the current net income of Syncona?Syncona's last 12 months net income is ($12M).
How many companies Syncona has acquired to date?As of October 2026, Syncona has acquired 2 companies.
What was the largest acquisition by Syncona?$28M acquisition of Freeline on 22nd November 2023 was the largest M&A Syncona has done to date.
What companies Syncona acquired?Syncona acquired Freeline and AGTC.
In how many companies Syncona has invested to date?As of October 2026, Syncona has invested in 30 companies.
What was the last Syncona investment?On 13th October 2026 Syncona invested in Vision Robotics Technology, participating in a Angel round, alongside Hyundai.
In what companies Syncona invested in?Syncona invested in Beacon Therapeutics, Quell Therapeutics, Gyroscope Therapeutics, Achilles Therapeutics, Anaveon, Freeline, Neogene Therapeutics, Purespring Therapeutics, OMass Therapeutics, Clade Therapeutics, iOnctura, Autolus Therapeutics, SwanBio Therapeutics, Spur Therapeutics, Nightstar Therapeutics, Azeria Therapeutics, Forcefield Therapeutics, Resolution Therapeutics, Blue Earth Diagnostics, Mosaic Therapeutics, and 10 other companies.

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