Axogen Valuation Multiples

Axogen is valued at $2.1B as of October 2026, a 7.3x revenue multiple. In the last 12 months, Axogen revenue was $272M and Axogen EBITDA was $32M.

Axogen Overview

About Axogen

Axogen Inc is engaged in the science, development, and commercialization of technologies for peripheral nerve regeneration and repair. The company provides clinically and economically effective repair solutions for surgeons and health care providers. Its products include Avance Nerve Graft, Axoguard Nerve Connector, Axoguard Nerve Protector, Axoguard Nerve Cap, and Avive Soft Tissue Membrane. It also offers an Axotouch Two-Point Discriminator used to measure the innervation density of any surface area of the skin. Its products are available in the United States, Canada, Germany, the United Kingdom, Spain, and several other countries.


Founded

1977

HQ

United States

Employees

622

Financials (LTM)

Revenue: $272M
EBITDA: $32M

EV

$2B

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Axogen Financials

Axogen reported last 12-month revenue of $272M and EBITDA of $32M.

In the same LTM period, Axogen generated $200M in gross profit, $32M in EBITDA, and had net loss of ($22M).

Revenue (LTM)


Axogen P&L

In the most recent fiscal year, Axogen reported revenue of $225M and EBITDA of $507K.

Axogen is unprofitable as of last fiscal year, with gross margin of 74%, EBITDA margin of 0%, and net margin of (7%).

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LTMLast FY202320242025202620272028
Revenue$272M$225M$159M$187M$225M
Gross Profit$200M$167M$122M$142M$167M
Gross Margin73%74%77%76%74%
EBITDA$32M$507K($13M)$6M$507K
EBITDA Margin12%0%(8%)3%0%
EBIT Margin(3%)(3%)(13%)(2%)(3%)
Net Profit($22M)($16M)($22M)($10M)($16M)
Net Margin(8%)(7%)(14%)(5%)(7%)
Net Debt-$15M---

Financial data powered by Morningstar, Inc.

Axogen Stock Performance

Axogen has current market cap of $2.1B, and enterprise value of $2B.

Market Cap Evolution


Axogen's stock price is $35.24.

Axogen share price decreased by 15.9% in the last 30 days, and increased by 58.6% in the last year.

Axogen has an EPS (earnings per share) of $-0.27.

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EVMarket CapPrice 1DPrice 1MPrice 3MPrice 12MEPS
$2B$2.1B1.8%-15.9%-16.5%58.6%$-0.27

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Axogen Valuation Multiples

Axogen trades at 7.3x EV/Revenue multiple, and 62.6x EV/EBITDA.

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EV / Revenue (LTM)


Axogen Financial Valuation Multiples

As of October 20, 2026, Axogen has market cap of $2.1B and EV of $2B.

Axogen has a P/E ratio of (91.9x).

LTMLast FY202320242025202620272028
EV/Revenue7.3x8.8x12.4x10.5x8.8x
EV/EBITDA62.6xn/m(148.3x)n/mn/m
EV/EBIT(242.8x)n/m(92.1x)n/mn/m
EV/Gross Profit9.9x11.8x16.2x13.9x11.8x
P/E(91.9x)(131.7x)(95.2x)(207.5x)(131.7x)
EV/FCFn/mn/m(95.8x)n/mn/m

Multiples above and below 250x are considered non-meaningful (n/m). Valuation data powered by FactSet, Inc. and Morningstar, Inc.

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Axogen Margins & Growth Rates

Axogen grew revenue by 26% and EBITDA by 6399% in the last fiscal year.

In the most recent fiscal year, Axogen reported gross margin of 74%, EBITDA margin of 0%, and net margin of (7%).

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Axogen Margins

Last FY202420252026202720282029
Gross Margin74%76%74%73%
EBITDA Margin0%3%0%12%
EBIT Margin(3%)(2%)(3%)(3%)
Net Margin(7%)(5%)(7%)(9%)
FCF Margin(2%)0%(2%)3%

Axogen Growth Rates

FY+1/FY23/2424/2525/2626/2727/2828/29
Revenue Growth26%18%20%26%
Gross Profit Growth24%16%18%24%
EBITDA Growth6399%(146%)(92%)6399%
EBIT Growth5%(85%)139%5%
Net Profit Growth54%(54%)58%54%
FCF Growth(253%)(100%)(43573%)(253%)

Data powered by FactSet, Inc. and Morningstar, Inc.

Axogen Operational KPIs

Axogen's revenue per employee in the last FY averaged $0.4M, while opex per employee averaged $0.3M for the same period.

Axogen's Rule of 40 is 38% (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Axogen's Rule of X is 77% (created by Bessemer, Rule of X is another metric to measure SaaS companies, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

Access forward-looking KPIs for Axogen
LTMLast FY202320242025202620272028
Rule of 4039%38%---
Bessemer Rule of X79%77%---
Revenue per Employee-$0.4M---
Opex per Employee-$0.3M---
S&M Expenses to Revenue44%43%49%42%43%
G&A Expenses to Revenue19%20%24%21%20%
R&D Expenses to Revenue13%15%17%15%15%
Opex to Revenue-78%90%78%78%

Data powered by FactSet, Inc. and Morningstar, Inc.

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Axogen Competitors

Axogen competitors include Inspire Medical Systems, Rigaku, Heron Neutron Medical, Butterfly Network, Elekta, SKAN Group, LeMaitre Vascular, UFP Technologies, AddLife and Fukuda Denshi.

Most Axogen public comparables operate across Medical Devices, DeepTech, HealthTech and BioTech.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
Inspire Medical Systems$912M$62M1.9x2.0x27.9x9.2x
Rigaku$596M$138M4.0x3.7x17.2x15.5x
Heron Neutron Medical$318K($15M)5810.4x-(122.9x)-
Butterfly Network$98M($73M)19.3x16.1x(25.7x)(89.3x)
Elekta$1.7B$135M1.6x1.5x19.4x8.8x
SKAN Group$404M$43M5.1x4.4x47.4x31.1x
LeMaitre Vascular$250M$91M6.8x6.3x18.7x20.0x
UFP Technologies$603M$112M4.0x3.7x21.5x18.3x

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Acquisitions by Axogen

Axogen has acquired 1 company to date.

Last acquisition by Axogen was on September 10th 2026. Axogen acquired BioCircuit Technologies for $200M (EV/Revenue multiple available to Pro users).

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Latest Acquisitions by Axogen

BioCircuit Technologies
Description
BioCircuit Technologies is a developer of noninvasive electrophysiology devices for peripheral nerve monitoring, control, and repair. The Boston-based firm produces wearable sensors enabling early diagnosis, symptom tracking, and personalized treatment in neurology clinics.
HQ CountryUnited States
HQ City
Atlanta, GA
Deal Date10 Sep 2026
Valuation$200M
EV/Revenue
EV/EBITDA

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Investments by Axogen

Axogen has invested in 1 company to date.

Latest investment by Axogen was on July 28th 2026. Axogen invested in Trace Biosciences in their Series A round.

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Latest Investments by Axogen

Trace Biosciences
Description
Trace Biosciences is a developer of near-infrared fluorescence imaging agents for surgical nerve visualization. Boston-headquartered, the company creates targeted probes compatible with existing clinical systems to highlight nerves in real time during operations across oncology, neurology, and general surgery. With IND-enabling studies completed, Trace Biosciences advances toward Phase I trials for applications in robotic-assisted procedures.
HQ CountryUnited States
HQ City
Portland, OR
Deal Date28 Jul 2026
RoundSeries A
Raisedundisclosed
InvestorsAxogen
Valuationundisclosed
EV/Revenue
EV/EBITDA

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About Axogen

When was Axogen founded?Axogen was founded in 1977.
Where is Axogen headquartered?Axogen is headquartered in United States.
How many employees does Axogen have?As of today, Axogen has over 622 employees.
Who is the CEO of Axogen?Axogen's CEO is Michael J. Dale.
Is Axogen publicly listed?Yes, Axogen is a public company listed on Nasdaq.
What is the stock symbol of Axogen?Axogen trades under AXGN ticker.
When did Axogen go public?Axogen went public in 1986.
Who are competitors of Axogen?Axogen main competitors include Inspire Medical Systems, Rigaku, Heron Neutron Medical, Butterfly Network, Elekta, SKAN Group, LeMaitre Vascular, UFP Technologies, AddLife, Fukuda Denshi.
What is the current market cap of Axogen?Axogen's current market cap is $2.1B.
What is the current revenue of Axogen?Axogen's last 12 months revenue is $272M.
What is the current revenue growth of Axogen?Axogen revenue growth (NTM/LTM) is 27%.
What is the current EV/Revenue multiple of Axogen?Current revenue multiple of Axogen is 7.3x.
What is the current EBITDA of Axogen?Axogen's last 12 months EBITDA is $32M.
What is Axogen's EBITDA margin?Axogen's last 12 months EBITDA margin is 12%.
What is the current EV/EBITDA multiple of Axogen?Current EBITDA multiple of Axogen is 62.6x.
What is the current FCF of Axogen?Axogen's last 12 months FCF is $4M.
What is Axogen's FCF margin?Axogen's last 12 months FCF margin is 2%.
What is the current EV/FCF multiple of Axogen?Current FCF multiple of Axogen is 447.1x.
How many companies Axogen has acquired to date?As of October 2026, Axogen has acquired 1 company.
What was the largest acquisition by Axogen?$200M acquisition of BioCircuit Technologies on 10th September 2026 was the largest M&A Axogen has done to date.
What companies Axogen acquired?Axogen acquired BioCircuit Technologies.
In how many companies Axogen has invested to date?As of October 2026, Axogen has invested in 1 company.
What was the last Axogen investment?On 28th July 2026 Axogen invested in Trace Biosciences, participating in a Series A round.
In what companies Axogen invested in?Axogen invested in Trace Biosciences.

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