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- SafeHeal
SafeHeal Funding, Investors & Competitors
SafeHeal has raised $104M across 4 funding rounds, most recently a $12M Series C in September 2025.
Last SafeHeal funding round
$12M
Series C · Sep 2025
Cumulative funding SafeHeal raised
$104M
across 4 funding rounds
Key investors in SafeHeal
Sofinnova Partners
Gideon Strategic Partners
Asabys Partners
M&L Healthcare Investments
Genesis Medtech
Solar Eclipse
About SafeHeal
SafeHeal is a medtech company developing the SafeEnterostomy device for temporary intestinal stoma protection post-surgery. The patch facilitates natural anastomosis healing without colostomy bags, reducing infection risks and hospital stays. Incubated by MD Start in France and backed by Sofinnova Partners, SafeHeal has earned awards from Concours Mondial de l’Innovation, iLab, and Biovision. The Paris-based firm advances clinical trials for colorectal procedures.
Founded
2015
HQ
Website
Status
Privately held
Customer focus
B2B
Revenue model
Product sales
SafeHeal Funding History
SafeHeal has raised a total of $104M across 4 funding rounds.
SafeHeal's first fundraising round was a $7M Series A in March 2018. The most recent completed round was a $12M Series C in September 2025.
SafeHeal funding rounds
| Date | Stage | Investors | Raised | Deal Summary |
|---|---|---|---|---|
| Sep 2025 | Series C | Asabys Partners (lead); Gideon Strategic Partners | $12M | SafeHeal is a medical device company developing Colovac, a temporary endoluminal bypass device designed as an alternative to temporary stomas for colorectal cancer patients undergoing resection surgery, improving recovery, outcomes, and quality of life. The company, headquartered in Paris with a U.S. subsidiary in Tampa, Fla., secured European MDR marketing approval for Colovac and FDA Breakthrough Device Designation. Colovac has been studied in the U.S., Europe, and Asia. On September 10, 2025, SafeHeal announced a €10 million extension to its oversubscribed €35 million Series C financing, bringing the total Series C to €45 million. Asabys Partners led the extension through its Sabadell Asabys II fund, joining the syndicate that includes Sofinnova Partners, Solar Eclipse, Gideon Strategic Partners, Polis, M&L Healthcare, and a leading multinational life sciences corporation. Gideon Strategic Partners increased its participation. The funds will accelerate SafeHeal’s U.S. IDE pivotal study and support EU commercial launch. The initial €35 million Series C was led by Solar Eclipse, with new investors Gideon Strategic Partners and M&L Healthcare, plus returning investors Sofinnova Partners and a multinational life sciences corporation. |
| Apr 2025 | Series C | Solar Eclipse (lead); Sofinnova Partners; M&L Healthcare Investments; Gideon Strategic Partners | $40M | SafeHeal is a medtech company developing Colovac, a temporary endoluminal fecal bypass system designed as a less-invasive alternative to diverting ostomy for patients undergoing colorectal resection, particularly for colorectal cancer, potentially eliminating the need for a second surgery and improving quality of life. The device has received FDA Breakthrough Device Designation following successful studies in over 100 patients across the U.S., Europe, and Asia. In April 2025, SafeHeal closed an oversubscribed €35 million Series C equity financing round led by Solar Eclipse, with participation from new investors Gideon Strategic Partners and M&L Healthcare Investments (part of M&L Group), and returning investor Sofinnova Partners. Proceeds from the €35 million round are allocated to complete SafeHeal's IDE pivotal study and accelerate preparations for the commercial launch of Colovac. The financing positions the company well for achieving key milestones toward FDA approval and commercialization. Martin Sands and Steven Sands from Solar Eclipse joined the board as member and observer, respectively. SafeHeal's technology addresses a significant unmet need in colon resection treatments, which currently involve high morbidity, risk of permanent stoma, and reduced quality of life. Investors, including Sofinnova Partners (involved since inception via their MDStart accelerator), express strong confidence in the platform's potential to revolutionize ostomy care. |
| Jan 2022 | Series B | Genesis Medtech (lead); Sofinnova Partners (lead) | $45M | SafeHeal is a medical device company developing the Colovac device, an endoluminal bypass sheath designed for digestive surgery applications, specifically addressing treatment options for colorectal cancer patients undergoing colon resection. The company announced a €40 million financing in January 2022 co-led by Sofinnova Partners and Genesis MedTech Group (headquartered in Singapore), with Sofinnova Partners noted as a historic shareholder having backed the company since its inception through its MD Start medtech accelerator platform. The financing was initiated following positive outcomes from SafeHeal's first clinical studies and was designated to accelerate the company's investigational device exemption (IDE) pivotal clinical trial, called SAFE-2, which had already received FDA approval for initiation. SAFE-2 is a prospective, randomized pivotal study conducted at leading medical centers in the U.S. and Europe designed to evaluate the safety and efficacy of Colovac to support future regulatory approval in the United States. Neither post-money valuation, revenue, ARR, nor EBITDA figures were disclosed in the January 2022 announcement or related sources. The company subsequently completed a Series C extension round of €35 million in 2024 led by Solar Eclipse with participation from Gideon Strategic Partners, M&L Healthcare, and Sofinnova Partners, followed by an additional €10 million extension led by Asabys Partners in September 2025, indicating continued progress toward FDA approval and commercial launch. |
| Mar 2018 | Series A | Sofinnova Partners (lead) | $7M | SafeHeal is an early-stage medtech company founded in 2015 and specialized in digestive surgery, focused on developing the Colovac device—an endoluminal bypass system designed as an alternative to temporary stoma for colorectal cancer patients. In March 2018, SafeHeal closed a €6 million Series A financing round led by Sofinnova Partners, the medtech venture capital firm that had previously participated in the company's seed funding through its MD Start accelerator. The company used the proceeds to execute its clinical and regulatory strategy, launch commercial operations following CE mark approval, and continue R&D investments. At the time of the Series A, SafeHeal had already begun a CE mark study and successfully tested the Colovac device on seven patients, with clinical trial enrollment underway in France and plans to extend to hospitals in Germany, the UK, and the US. SafeHeal was recognized as a laureate of the Worldwide Innovation Challenge 2015 edition, attesting to its disruptive potential in the field. |
Who has invested in SafeHeal?
6 investors have backed SafeHeal across its funding rounds, including Sofinnova Partners, Gideon Strategic Partners, Asabys Partners, M&L Healthcare Investments, Genesis Medtech and Solar Eclipse.
Lead investors include Asabys Partners, Solar Eclipse, Genesis Medtech and Sofinnova Partners.
SafeHeal Investors
| Investor | HQ | Rounds | Role | First check |
|---|---|---|---|---|
| 3 | Lead | Mar 2018 | ||
| 2 | Participant | Apr 2025 | ||
| 1 | Lead | Sep 2025 | ||
| 1 | Lead | Jan 2022 | ||
This data is available for Pro users. Sign up to see all 6 SafeHeal investors. Start Free Trial | ||||
Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples
Sign up to see data on 350K+ funding rounds and disclosed revenue and EBITDA valuation multiples, from seed, through growth stage, to pre-IPO.
Start Free TrialSafeHeal Competitors
SafeHeal competitors include listed companies like Illumina, Demant, BillionToOne and Johnson & Johnson, and private ones like Wilson Wolf Corporation and Biosplice Therapeutics.
| Company | HQ | Status | Revenue | EBITDA | Valuation | Revenue Multiple |
|---|---|---|---|---|---|---|
| Publicly listed | $4.3B | $1.4B | $37B | 8.4x | ||
| Publicly listed | $3.5B | $782M | $9.7B | 3.2x | ||
| Publicly listed | $305M | $12M | $5.2B | 11.7x | ||
| Private | - | $55M | $1.3B | - | ||
| Publicly listed | $94B | $40B | $651B | 6.8x | ||
| Private | - | - | $12B | - |
SafeHeal Public Comps
SafeHeal is still privately-owned, but its public comps include Samsung, Johnson & Johnson, Roche, Thermo Fisher Scientific, Siemens, Abbott, Danaher, Intuitive Surgical, Medtronic and Stryker.
| Last FY | EV/Revenue | EV/EBITDA | ||||||
|---|---|---|---|---|---|---|---|---|
| Revenue | EBITDA | Last FY | LTM | 2027E | Last FY | LTM | 2027E | |
| $243B | $67B | 4.4x | 2.4x | 15.8x | 4.4x | |||
| $94B | $40B | 7.2x | 6.8x | 17.0x | 18.3x | |||
| $77B | $26B | 5.0x | 4.9x | 14.6x | 12.4x | |||
| $45B | $11B | 6.3x | 6.0x | 26.8x | 23.6x | |||
| $91B | $15B | 3.0x | 2.9x | 18.1x | 15.7x | |||
| $44B | $12B | 4.6x | 4.2x | 17.4x | 15.8x | |||
| $25B | $6.9B | 7.0x | 6.6x | 24.8x | 21.1x | |||
| $10B | $3.6B | 13.0x | 11.6x | 36.6x | 25.7x | |||
This data is available for Pro users. Sign up to see all SafeHeal competitors and their valuation data. Start Free Trial | ||||||||
Common questions about SafeHeal
| When was SafeHeal founded? | SafeHeal was founded in 2015. |
| Where is SafeHeal headquartered? | SafeHeal is headquartered in Paris, France. |
| Is SafeHeal publicly listed? | No, SafeHeal is a private, VC-backed company. |
| How much funding has SafeHeal raised? | SafeHeal has raised $104M across 4 funding rounds. |
| What was SafeHeal's last funding round? | SafeHeal's last funding round was a $12M Series C in September 2025, led by Asabys Partners. |
| Who are SafeHeal's investors? | SafeHeal's investors include Sofinnova Partners, Gideon Strategic Partners, Asabys Partners, Genesis Medtech, Solar Eclipse and M&L Healthcare Investments. |
| Which companies are comparable to SafeHeal? | Companies comparable to SafeHeal include Illumina, Demant, BillionToOne, Wilson Wolf Corporation, Johnson & Johnson and Biosplice Therapeutics. |
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