NorthStar Medical Radioisotopes Funding, Investors & Competitors

NorthStar Medical Radioisotopes has raised $260M across 3 funding rounds, most recently a $185M undisclosed-stage round in September 2026.

Last NorthStar Medical Radioisotopes funding round

$185M

Undisclosed stage · Sep 2026

Cumulative funding NorthStar Medical Radioisotopes raised

$260M

across 3 funding rounds

Key investors in NorthStar Medical Radioisotopes

NorthStar Medical Radioisotopes Overview

About NorthStar Medical Radioisotopes

NorthStar Medical Radioisotopes is a Beloit, Wisconsin-based producer of medical radioisotopes, specializing in non-uranium-based molybdenum-99 for technetium-99m generators used in over 40,000 daily U.S. cardiac and cancer imaging procedures. Founded in 2006 as a subsidiary of NorthStar Medical Technologies, the company operates the only commercial-scale electron accelerator facility in North America for Mo-99 production, achieving FDA clearance in 2021 and supplying hospitals nationwide through distribution partners. NorthStar also develops CDMO services for alpha and beta emitters like actinium-225 and copper-67 to advance targeted radiopharmaceutical therapies.


Founded

2006

HQ

United StatesMadison, WI

Status

Privately held

Customer focus

B2B

Revenue model

Product sales

NorthStar Medical Radioisotopes Funding History

NorthStar Medical Radioisotopes has raised a total of $260M across 3 funding rounds.

NorthStar Medical Radioisotopes' first fundraising round was a $300K pre-seed round in September 2015. The most recent completed round was a $185M undisclosed-stage round in September 2026.

NorthStar Medical Radioisotopes funding rounds

NorthStar Medical Radioisotopes funding rounds
DateStageInvestorsRaisedDeal Summary
Sep 2026Undisclosed stageHercules Capital (lead)$185MNorthStar Medical Technologies, LLC secured a multi-year growth capital facility of up to $185 million from Hercules Capital, Inc. in September 2026, including $100 million upfront, to support continued growth and expansion of its radiopharmaceutical and isotope-production platform. The financing is structured as growth capital rather than an acquisition, and the capital is intended to accelerate investment in no-carrier-added actinium-225 production and clinical and commercial drug-manufacturing capabilities for next-generation precision cancer therapies. The transaction supports NorthStar’s vertically integrated radiopharmaceutical campus, including co-located isotope production and contract development and manufacturing operations, with the stated goal of scaling supply for targeted alpha therapies and broader partner demand. NorthStar is described as the first commercial-scale producer of no-carrier-added actinium-225 using electron-accelerator technology, with the company working with pharmaceutical and biotechnology partners to expand patient access to precision cancer treatments.
Apr 2019Undisclosed stageOberland Capital (lead)$75MNorthStar Medical Radioisotopes (NorthStar Medical Technologies, LLC) is a global innovator in the production and distribution of radioisotopes used for medical imaging and therapy, specializing in domestic production of molybdenum-99 (Mo-99) without highly enriched uranium and the RadioGenix System for technetium-99m (Tc-99m) generation. On April 23, 2019, the company closed a $100 million secured financing with Oberland Capital Management LLC, receiving $75 million at closing and the option to draw an additional $25 million by December 31, 2020. Proceeds were earmarked primarily to expand U.S. Mo-99 production capacity, enhance production efficiency, implement RadioGenix System improvements, and advance R&D activities. Oberland Capital, the lead investor, highlighted NorthStar's alignment with their focus on commercial-stage healthcare companies addressing unmet needs, positioning NorthStar as the first domestic Mo-99 producer in over 30 years to ensure reliable Tc-99m supply for diagnostic imaging. NorthStar's leadership emphasized the financing's role in executing their strategy for sustainable growth amid increasing market uptake of RadioGenix Systems, providing on-demand Tc-99m to customers. The transaction was described as cash-efficient, supporting continued commercial expansion. The company continues to focus on radioisotope supply chain reliability and radiopharmaceutical development for nuclear medicine applications.
Sep 2015Pre-seedStateline Angels (lead)$300K-

Who has invested in NorthStar Medical Radioisotopes?

3 investors have backed NorthStar Medical Radioisotopes across its funding rounds, including Hercules Capital, Stateline Angels and Oberland Capital.

Lead investors include Hercules Capital, Oberland Capital and Stateline Angels.


NorthStar Medical Radioisotopes Investors

Investors in NorthStar Medical Radioisotopes by funding rounds participated
InvestorHQRoundsRoleFirst check
Stateline AngelsUnited StatesRockford, IL1LeadSep 2015

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NorthStar Medical Radioisotopes Competitors

NorthStar Medical Radioisotopes competitors include listed companies like Illumina, Demant, BillionToOne and Johnson & Johnson, and private ones like Wilson Wolf Corporation and Biosplice Therapeutics.

Public and private companies comparable to NorthStar Medical Radioisotopes
CompanyHQStatusRevenueEBITDAValuationRevenue Multiple
IlluminaUnited StatesUnited StatesPublicly listed$4.3B$1.4B$32B7.2x
DemantDenmarkDenmarkPublicly listed$3.4B$761M$12B3.8x
BillionToOneUnited StatesUnited StatesPublicly listed$305M$12M$5.4B11.5x
Wilson Wolf CorporationUnited StatesSaint Paul, MNPrivate-$55M$1.3B-
Johnson & JohnsonUnited StatesUnited StatesPublicly listed$94B$40B$665B6.9x
Biosplice TherapeuticsUnited StatesSan Diego, CAPrivate--$12B-

NorthStar Medical Radioisotopes Public Comps

NorthStar Medical Radioisotopes is still privately-owned, but its public comps include Samsung, Johnson & Johnson, Roche, Thermo Fisher Scientific, Siemens, Abbott, Danaher, Intuitive Surgical, Medtronic and Stryker.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
Samsung$247B$68B3.1x1.6x11.3x2.7x
Johnson & Johnson$94B$40B7.4x6.9x17.3x18.8x
Roche$78B$26B5.3x5.3x15.7x13.3x
Thermo Fisher Scientific$45B$11B6.6x6.2x27.9x24.0x
Siemens$88B$15B3.0x2.8x18.0x15.5x
Abbott$44B$12B4.9x4.4x18.5x16.8x
Danaher$25B$6.9B7.4x7.0x26.4x22.0x
Intuitive Surgical$10B$3.6B15.2x13.1x43.0x28.5x

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Common questions about NorthStar Medical Radioisotopes

When was NorthStar Medical Radioisotopes founded?NorthStar Medical Radioisotopes was founded in 2006.
Where is NorthStar Medical Radioisotopes headquartered?NorthStar Medical Radioisotopes is headquartered in Madison, WI, United States.
Is NorthStar Medical Radioisotopes publicly listed?No, NorthStar Medical Radioisotopes is a private, VC-backed company.
How much funding has NorthStar Medical Radioisotopes raised?NorthStar Medical Radioisotopes has raised $260M across 3 funding rounds.
What was NorthStar Medical Radioisotopes' last funding round?NorthStar Medical Radioisotopes' last funding round was a $185M undisclosed-stage round in September 2026, led by Hercules Capital.
Who are NorthStar Medical Radioisotopes' investors?NorthStar Medical Radioisotopes' investors include Stateline Angels, Hercules Capital and Oberland Capital.
Which companies are comparable to NorthStar Medical Radioisotopes?Companies comparable to NorthStar Medical Radioisotopes include Illumina, Demant, BillionToOne, Wilson Wolf Corporation, Johnson & Johnson and Biosplice Therapeutics.

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