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Inspire Medical Systems Valuation Multiples

Discover revenue and EBITDA valuation multiples for Inspire Medical Systems and similar public comparables like Medartis, Shinva, Alphatec Holdings, Avanos Medical and more.

Inspire Medical Systems Overview

About Inspire Medical Systems

Inspire Medical Systems Inc operates as a medical technology company. It focuses on the development and commercialization of minimally invasive solutions for patients with obstructive sleep apnea (OSA). It offers Inspire system, a neurostimulation technology that provides a safe and effective treatment for moderate to severe obstructive sleep apnea. The firm has operating footprints in the United States and All other countries wherein, it generates a majority of its revenue from the United States. Its segment revenues are derived from the sales of its product, the Inspire system, to hospitals and ambulatory surgery centers in the U.S. and in selected countries in Europe and the Asia Pacific region.


Founded

2007

HQ

United States

Employees

1.3K

Financials (LTM)

Revenue: $886M
EBITDA: $192M

EV

$971M

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Inspire Medical Systems Financials

Inspire Medical Systems reported last 12-month revenue of $886M and EBITDA of $192M.

In the same LTM period, Inspire Medical Systems generated $758M in gross profit, $192M in EBITDA, and $100M in net income.

Revenue (LTM)


Inspire Medical Systems P&L

In the most recent fiscal year, Inspire Medical Systems reported revenue of $912M and EBITDA of $203M.

Inspire Medical Systems is profitable as of last fiscal year, with gross margin of 85%, EBITDA margin of 22%, and net margin of 16%.

See analyst estimates for Inspire Medical Systems
LTMLast FY202320242025202620272028
Revenue$886M$912M$625M$803M$912M
Gross Profit$758M$779M$528M$680M$779M
Gross Margin86%85%85%85%85%
EBITDA$192M$203M($17M)$65M$80M
EBITDA Margin22%22%(3%)8%9%
EBIT Margin6%7%(6%)4%6%
Net Profit$100M$145M($21M)$54M$145M
Net Margin11%16%(3%)7%16%

Financial data powered by Morningstar, Inc.

Inspire Medical Systems Stock Performance

Inspire Medical Systems has current market cap of $1B, and enterprise value of $971M.

Market Cap Evolution


Inspire Medical Systems' stock price is $42.53.

Inspire Medical Systems share price decreased by 24.2% in the last 30 days, and by 69.2% in the last year.

Inspire Medical Systems has an EPS (earnings per share) of $5.05.

See more trading valuation data for Inspire Medical Systems
EVMarket CapPrice 1DPrice 1MPrice 3MPrice 12MEPS
$971M$1B1.7%-24.2%-34.1%-69.2%$5.05

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Inspire Medical Systems Valuation Multiples

Inspire Medical Systems trades at 1.1x EV/Revenue multiple, and 5.1x EV/EBITDA.

See NTM and 2027E valuation multiples for Inspire Medical Systems

EV / Revenue (LTM)


Inspire Medical Systems Financial Valuation Multiples

As of May 20, 2026, Inspire Medical Systems has market cap of $1B and EV of $971M.

Inspire Medical Systems has a P/E ratio of 12.3x.

LTMLast FY202320242025202620272028
EV/Revenue1.1x1.1x1.6x1.2x1.1x
EV/EBITDA5.1x4.8x(56.9x)14.9x12.2x
EV/EBIT19.2x14.7x(24.1x)26.9x19.1x
EV/Gross Profit1.3x1.2x1.8x1.4x1.2x
P/E12.3x8.4x(57.9x)22.9x8.4x
EV/FCF5.9x5.9xn/m10.7x12.4x

Multiples above and below 250x are considered non-meaningful (n/m). Valuation data powered by FactSet, Inc. and Morningstar, Inc.

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Inspire Medical Systems Margins & Growth Rates

Inspire Medical Systems decreased revenue by 8% and EBITDA by 14% in the last fiscal year.

In the most recent fiscal year, Inspire Medical Systems reported gross margin of 85%, EBITDA margin of 22%, and net margin of 16%.

See estimated margins and future growth rates for Inspire Medical Systems

Inspire Medical Systems Margins

Last FY202420252026202720282029
Gross Margin85%85%85%86%
EBITDA Margin22%8%9%21%
EBIT Margin7%4%6%3%
Net Margin16%7%16%3%
FCF Margin18%11%9%20%

Inspire Medical Systems Growth Rates

FY+1/FY23/2424/2525/2626/2727/2828/29
Revenue Growth(8%)28%14%(8%)
Gross Profit Growth(7%)29%15%(7%)
EBITDA Growth(14%)(481%)23%118%
EBIT Growth(61%)(190%)41%(49%)
Net Profit Growth(82%)(353%)172%(82%)
FCF Growth(0%)8799%(14%)110%

Data powered by FactSet, Inc. and Morningstar, Inc.

Inspire Medical Systems Operational KPIs

Inspire Medical Systems' revenue per employee in the last FY averaged $0.7M, while opex per employee averaged $0.5M for the same period.

Inspire Medical Systems' Rule of 40 is 13% (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Inspire Medical Systems' Rule of X is 2% (created by Bessemer, Rule of X is another metric to measure SaaS companies, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

Access forward-looking KPIs for Inspire Medical Systems
LTMLast FY202320242025202620272028
Rule of 4019%13%
Bessemer Rule of X14%2%
Revenue per Employee$0.7M
Opex per Employee$0.5M
S&M Expenses to Revenue38%35%35%
G&A Expenses to Revenue11%10%10%
R&D Expenses to Revenue12%11%19%14%11%
Opex to Revenue80%91%80%80%

Data powered by FactSet, Inc. and Morningstar, Inc.

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Inspire Medical Systems Competitors

Inspire Medical Systems competitors include Medartis, Shinva, Alphatec Holdings, Avanos Medical, Arcs Co, SKAN Group, Integra Lifesciences, iRadimed, Shanghai Haohai and El.En. Group.

Most Inspire Medical Systems public comparables operate across Medical Devices, DeepTech and HealthTech.

EV/RevenueEV/EBITDA
Last FYLTM2027ELast FYLTM2027E
Medartis4.0x3.7x23.5x21.8x
Shinva0.6x7.2x
Alphatec Holdings2.3x2.1x18.5x15.8x
Avanos Medical1.8x1.7x14.2x13.9x
Arcs Co0.2x0.2x4.5x4.3x
SKAN Group3.2x3.0x27.9x24.1x
Integra Lifesciences1.8x1.8x9.2x9.0x
iRadimed12.7x12.3x39.0x36.9x

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Inspire Medical Systems Funding History

Before going public, Inspire Medical Systems raised $80M in total equity funding, across 3 rounds.


Inspire Medical Systems Funding Rounds

DateStageRaised FromRaisedValuationRev. MultipleDeal Summary
Nov-16Series FAmzak Capital Management; Kleiner Perkins; Medtronic; OrbiMed; Synergy Life Science Partner; U.S. Venture Partners$38MInspire Medical Systems develops the Inspire therapy, an implantable neurostimulation system for treating obstructive sleep apnea (OSA) in patients unable to tolerate CPAP machines, featuring a closed-loop device that stimulates nerves to keep airways open during sleep. The company achieved key milestones including FDA PMA approval post-STAR trial publication in the New England Journal of Medicine, Medicare coverage in all 50 states, and international expansions. For fiscal year 2016, ending near the November 2016 funding round led by Amzak Capital Management with participation from Kleiner Perkins, Medtronic, OrbiMed, Synergy Life Science Partners, and U.S. Venture Partners, Inspire reported revenue of $16.4 million, up 105% from $8.0 million in fiscal 2015, driven by increased sales volume, market penetration, and sales territory expansion. Gross margin improved to 76.2% from 64.9%, though net loss was $18.5 million amid ongoing investments. The company continued rapid growth post-2016, reaching $28.6 million revenue in 2017 with 78.9% gross margin and net loss of $17.5 million, culminating in a NYSE IPO and scaling to $625 million revenue by 2023 with over 85,000 patients treated in a $10 billion underpenetrated U.S. market.
May-14Series EAperture Venture Partners; GDN Holdings; Johnson & Johnson Development Corporation; Kleiner Perkins; Medtronic; OrbiMed; Synergy Life Science Partner; TGap Ventures; U.S. Venture Partners$40MInspire Medical Systems, a Minneapolis-based medical device company, develops the Inspire Upper Airway Stimulation (UAS) therapy, a fully implanted neurostimulation system for treating obstructive sleep apnea (OSA) in patients unable to use or adhere to CPAP therapy. The system uses a pulse generator, sensing lead, and stimulation lead, activated by a handheld remote, to detect breathing patterns and stimulate airway muscles to keep airways open during sleep. FDA-approved shortly before the round, the therapy targets a market gap amid low CPAP adherence rates of around 50%, with OSA linked to serious health risks like heart attack, stroke, and high healthcare costs. On May 15, 2014, Inspire Medical Systems raised $40 million in a Series E funding round led by OrbiMed, coinciding with the U.S. commercial launch of Inspire therapy. New investors included Johnson & Johnson Development Corporation and Aperture Venture Partners, while existing backers such as Kleiner Perkins Caufield & Byers, U.S. Venture Partners, Synergy Life Science Partners, Medtronic, GDN Holdings, and TGap Ventures also participated. OrbiMed's Chau Q. Khuong joined the board. The funds were earmarked to support hiring, programs, and commercialization efforts for the therapy, originally a Medtronic spinout that had prior European approval. The round highlighted strong investor confidence in Inspire's innovative OSA solution, filling a treatment continuum gap with established neurostimulation tech and proprietary algorithms tailored to patient breathing. Inspire later raised additional rounds, including a Series F in 2016 and an IPO in 2018 raising $108 million, with total VC funding reaching $109 million over eight rounds.
Aug-13Series D$2M

Inspire Medical Systems Investment Activity

Inspire Medical Systems has invested in 2 companies to date.

Latest investment by Inspire Medical Systems was on June 25th 2025. Inspire Medical Systems invested in EnsoData in their $20M Series B round (EV/Revenue multiple of ).

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Latest Investments by Inspire Medical Systems

EnsoData
EnsoData
Ognomy
Description
Ognomy is a virtual care platform based in Tel Aviv, Israel, specializing in end-to-end sleep apnea management. Launched in 2020, it connects patients with board-certified sleep physicians for remote consultations, home sleep testing kits, customized CPAP prescriptions, and ongoing therapy monitoring through its HIPAA-compliant app. The service partners with insurers like Aetna and has treated over 10,000 patients across the US.
HQ CountryUnited StatesUnited StatesUnited States
HQ City
Buffalo, NY
Deal Date25 Jun 202527 Apr 202227 Apr 2022
RoundSeries BSeries ASeed
Raised$20M$20M$1M
InvestorsInspire Medical Systems; Questa Capital Management; Supermoon Capital; Venture Investors; Zetta Venture PartnersColle Capital Partners; Frederick Robertson; HealthX Ventures; Inspire Medical Systems; Justin Mortara; M25; Supermoon Capital; Venture Investors; Zetta Venture PartnersInspire Medical Systems; Launch NY
Valuationundisclosedundisclosed$9M
EV/Revenue
EV/EBITDA

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About Inspire Medical Systems

When was Inspire Medical Systems founded?Inspire Medical Systems was founded in 2007.
Where is Inspire Medical Systems headquartered?Inspire Medical Systems is headquartered in United States.
How many employees does Inspire Medical Systems have?As of today, Inspire Medical Systems has over 1K employees.
Who is the CEO of Inspire Medical Systems?Inspire Medical Systems' CEO is Timothy P. Herbert.
Is Inspire Medical Systems publicly listed?Yes, Inspire Medical Systems is a public company listed on NYSE.
What is the stock symbol of Inspire Medical Systems?Inspire Medical Systems trades under INSP ticker.
When did Inspire Medical Systems go public?Inspire Medical Systems went public in 2018.
Who are competitors of Inspire Medical Systems?Inspire Medical Systems main competitors include Medartis, Shinva, Alphatec Holdings, Avanos Medical, Arcs Co, SKAN Group, Integra Lifesciences, iRadimed, Shanghai Haohai, El.En. Group.
What is the current market cap of Inspire Medical Systems?Inspire Medical Systems' current market cap is $1B.
What is the current revenue of Inspire Medical Systems?Inspire Medical Systems' last 12 months revenue is $886M.
What is the current revenue growth of Inspire Medical Systems?Inspire Medical Systems revenue growth (NTM/LTM) is (3%).
What is the current EV/Revenue multiple of Inspire Medical Systems?Current revenue multiple of Inspire Medical Systems is 1.1x.
Is Inspire Medical Systems profitable?Yes, Inspire Medical Systems is EBITDA-positive (as of the last 12 months).
What is the current EBITDA of Inspire Medical Systems?Inspire Medical Systems' last 12 months EBITDA is $192M.
What is Inspire Medical Systems' EBITDA margin?Inspire Medical Systems' last 12 months EBITDA margin is 22%.
What is the current EV/EBITDA multiple of Inspire Medical Systems?Current EBITDA multiple of Inspire Medical Systems is 5.1x.
What is the current FCF of Inspire Medical Systems?Inspire Medical Systems' last 12 months FCF is $165M.
What is Inspire Medical Systems' FCF margin?Inspire Medical Systems' last 12 months FCF margin is 19%.
What is the current EV/FCF multiple of Inspire Medical Systems?Current FCF multiple of Inspire Medical Systems is 5.9x.
How many companies Inspire Medical Systems has acquired to date?Inspire Medical Systems hasn't acquired any companies yet (or none have been disclosed publicly).
In how many companies Inspire Medical Systems has invested to date?As of May 2026, Inspire Medical Systems has invested in 2 companies.
What was the last Inspire Medical Systems investment?On 25th June 2025 Inspire Medical Systems invested in EnsoData, participating in a $20M Series B round, alongside Questa Capital Management, Supermoon Capital, Venture Investors, and Zetta Venture Partners.
In what companies Inspire Medical Systems invested in?Inspire Medical Systems invested in EnsoData and Ognomy.

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