- Companies
- Lumicell
Lumicell Funding, Investors & Competitors
Lumicell has raised $231M across 4 funding rounds, most recently a $198M undisclosed-stage round in May 2025.
Last Lumicell funding round
$198M
Undisclosed stage · May 2025
Cumulative funding Lumicell raised
$231M
across 4 funding rounds
Key investors in Lumicell
LaunchCapital
BlueIO
Kodiak Venture Partners
About Lumicell
Lumicell is a medtech firm advancing fluorescence imaging for intraoperative cancer detection. Newton-headquartered since 2008, the company pairs LUM-015 contrast agents with handheld Luna scanners to highlight residual tumor cells during breast lumpectomy, colorectal resection, and glioma procedures. Clinical trials demonstrate 100 percent sensitivity in identifying cancer margins, supporting reduced re-excision rates. Investigations extend to pancreatic tumors, Barrett’s esophagus, and brain metastases.
Founded
2008
HQ
Website
Status
Privately held
Customer focus
B2B
Revenue model
Product sales
Sectors
Lumicell Funding History
Lumicell has raised a total of $231M across 4 funding rounds.
Lumicell's first fundraising round was a $2M seed round in February 2014. The most recent completed round was a $198M undisclosed-stage round in May 2025.
Lumicell funding rounds
| Date | Stage | Investors | Raised | Deal Summary |
|---|---|---|---|---|
| May 2025 | Undisclosed stage | - | $198M | Lumicell is a medical technology company developing fluorescence-guided imaging systems for real-time cancer detection during surgery, primarily focused on breast cancer lumpectomies with its LumiSystem™, comprising the FDA-approved LUMISIGHT™ (pegulicianine) imaging agent and Lumicell™ Direct Visualization System (DVS). The company launched the LumiSystem™ commercially in the U.S. in early 2025, with first commercial use reported in January 2025, and received a permanent HCPCS code in November 2024 and CMS transitional pass-through payment in September 2024 to support patient access. Lumicell is expanding its pipeline to other solid tumors, including gastrointestinal and esophageal cancers, with promising feasibility trial findings in GI cancer patients announced in April 2025 and a Phase I NIH SBIR contract for esophageal lesion detection. On May 6, 2025, Lumicell closed a Series F funding round raising $198.13 million led by investors including BlueIO, Index Ventures, Kodiak Venture Partners, and LaunchCapital, bringing total funding to $344.78 million across 17 rounds. Prior rounds include a $2.73 million Series E-III in July 2024 and a $4 million Grant-III in September 2024, with consistent participation from investors like BlueIO, Kodiak, LaunchCapital, and Quantum Valley Investments. The funding supports Lumicell's ongoing clinical and commercial expansion following FDA approvals and market entry. The company reported its first commercial use of LumiSystem™ in January 2025 and continued development in additional indications. Lumicell's competitive positioning leverages its proprietary pan-oncologic optical imaging agent and integrated drug-device-software platform to reduce re-excision rates in cancer surgeries. Key investors include National Cancer Institute and Rivas Capital LLC, with founders W. David Lee, Moungi G. Bawendi, and Andrey Zarur. Recent collaborations include Stand Up To Cancer for gastric cancer detection (2026) and Learn Look Locate for patient education (December 2025). |
| Jul 2024 | Seed | - | $3M | Lumicell, a company developing fluorescence imaging technology for real-time cancer detection during surgery, raised $2.73M in a Series E - III round on July 24, 2024, from investors including BlueIO, Kodiak Venture Partners, LaunchCapital, and Quantum Valley Investments. The technology focuses on intraoperative detection of residual cancer, particularly in breast cancer lumpectomy procedures. Following FDA approval of LUMISIGHT™ (pegulicianine) and the Lumicell™ Direct Visualization System (DVS), the company launched its LumiSystem™ commercially in the U.S. in Q4 2024. Lumicell has raised a total of $344.78M across 17 rounds, with subsequent funding including a $4M Grant - III on September 30, 2024, and a Series F round of $198.13M on May 6, 2025, led by investors such as Index Ventures. The company received a permanent HCPCS code for intraoperative fluorescence imaging margin assessments in November 2024. Investors include National Cancer Institute, Rivas Capital LLC, and others, with founders W. David Lee, Moungi G. Bawendi, and Andrey Zarur. |
| Oct 2017 | Series C | LaunchCapital; Kodiak Venture Partners; BlueIO | $29M | Lumicell, Inc. is an image-guided cancer surgery technology company based in Wellesley, Massachusetts, founded by researchers from the Koch Institute at MIT. The company developed the LUM System, comprising an injectable fluorescent agent and handheld imaging wand that detects cancer cells in real time during surgery by emitting light at specific wavelengths to illuminate tumor margins, aiming to reduce repeat surgeries and improve patient outcomes. The company closed a $28.7 million Series C financing round on December 7, 2017, led by new investors Launch Capital and BlueIO (affiliated with Kodiak Venture Partners), with participation from existing investors. The funding was designated to advance the clinical pipeline, including initiation of a pivotal Phase III trial in breast cancer and expansion of clinical studies into four additional solid tumor cancers including lung, ovarian, and brain cancer. At the time of the Series C round, Lumicell presented Phase II clinical trial data demonstrating that the LUM System could detect all breast cancer subtypes in 45 lumpectomy patients, including tumor margins as small as 1 mm, and the company had ongoing trials in prostate, colorectal, esophageal, and pancreatic cancers. |
| Feb 2014 | Seed | - | $2M | - |
Who has invested in Lumicell?
3 investors have backed Lumicell across its funding rounds, including LaunchCapital, BlueIO and Kodiak Venture Partners.
Lumicell Investors
| Investor | HQ | Rounds | Role | First check |
|---|---|---|---|---|
| 1 | Participant | Oct 2017 | ||
This data is available for Pro users. Sign up to see all 3 Lumicell investors. Start Free Trial | ||||
Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples
Sign up to see data on 350K+ funding rounds and disclosed revenue and EBITDA valuation multiples, from seed, through growth stage, to pre-IPO.
Start Free TrialLumicell Competitors
Lumicell competitors include listed companies like Johnson & Johnson, Roche, Thermo Fisher Scientific and Danaher, and private ones like Biosplice Therapeutics and Neuralink.
| Company | HQ | Status | Revenue | EBITDA | Valuation | Revenue Multiple |
|---|---|---|---|---|---|---|
| Publicly listed | $94B | $40B | $651B | 6.8x | ||
| Publicly listed | $77B | $26B | $351B | 4.9x | ||
| Publicly listed | $45B | $11B | $243B | 6.0x | ||
| Publicly listed | $25B | $6.9B | $149B | 6.6x | ||
| Private | - | - | $12B | - | ||
| Private | - | - | $9B | - |
Lumicell Public Comps
Lumicell is still privately-owned, but its public comps include Samsung, Johnson & Johnson, Roche, Thermo Fisher Scientific, Siemens, Abbott, Danaher, Intuitive Surgical, Medtronic and Stryker.
| Last FY | EV/Revenue | EV/EBITDA | ||||||
|---|---|---|---|---|---|---|---|---|
| Revenue | EBITDA | Last FY | LTM | 2027E | Last FY | LTM | 2027E | |
| $243B | $67B | 4.4x | 2.4x | 15.8x | 4.4x | |||
| $94B | $40B | 7.2x | 6.8x | 17.0x | 18.3x | |||
| $77B | $26B | 5.0x | 4.9x | 14.6x | 12.4x | |||
| $45B | $11B | 6.3x | 6.0x | 26.8x | 23.6x | |||
| $91B | $15B | 3.0x | 2.9x | 18.1x | 15.7x | |||
| $44B | $12B | 4.6x | 4.2x | 17.4x | 15.8x | |||
| $25B | $6.9B | 7.0x | 6.6x | 24.8x | 21.1x | |||
| $10B | $3.6B | 13.0x | 11.6x | 36.6x | 25.7x | |||
This data is available for Pro users. Sign up to see all Lumicell competitors and their valuation data. Start Free Trial | ||||||||
Common questions about Lumicell
| When was Lumicell founded? | Lumicell was founded in 2008. |
| Where is Lumicell headquartered? | Lumicell is headquartered in Boston, MA, United States. |
| Is Lumicell publicly listed? | No, Lumicell is a private, VC-backed company. |
| How much funding has Lumicell raised? | Lumicell has raised $231M across 4 funding rounds. |
| What was Lumicell's last funding round? | Lumicell's last funding round was a $198M undisclosed-stage round in May 2025. |
| Who are Lumicell's investors? | Lumicell's investors include LaunchCapital, Kodiak Venture Partners and BlueIO. |
| Which companies are comparable to Lumicell? | Companies comparable to Lumicell include Johnson & Johnson, Roche, Thermo Fisher Scientific, Danaher, Biosplice Therapeutics and Neuralink. |
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