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Stoke Therapeutics Inc is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine. Its proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to restore naturally-occurring protein levels selectively. Its first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome. The company provides early programs focused on multiple targets, including haploinsufficiency diseases of the central nervous system and eye, to up-regulate the protein expression of the underlying disease gene in a mutation-agnostic manner.
2014
128
LTM Revenue $43.3M
LTM EBITDA -$94.7M
$194M
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Stoke Therapeutics has a last 12-month revenue of $43.3M and a last 12-month EBITDA of -$94.7M.
In the most recent fiscal year, Stoke Therapeutics achieved revenue of $36.6M and an EBITDA of -$99.2M.
Stoke Therapeutics expects next 12-month revenue of XXX and NTM EBITDA of XXX
See Stoke Therapeutics valuation multiples based on analyst estimates| FY 2023 | FY 2024 | FY 2025 | LTM | NTM | |
|---|---|---|---|---|---|
| Revenue | $8.8M | $36.6M | XXX | XXX | XXX |
| Gross Profit | n/a | n/a | XXX | XXX | XXX |
| Gross Margin | NaN% | NaN% | XXX | XXX | XXX |
| EBITDA | -$112M | -$99.2M | XXX | XXX | XXX |
| EBITDA Margin | -1279% | -271% | XXX | XXX | XXX |
| Net Profit | -$101M | -$105M | XXX | XXX | XXX |
| Net Margin | -1151% | -286% | XXX | XXX | XXX |
| Net Debt | n/a | n/a | XXX | XXX | XXX |
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As of April 15, 2025, Stoke Therapeutics's stock price is $8.
Stoke Therapeutics has current market cap of $409M, and EV of $194M.
See Stoke Therapeutics trading valuation data| EV | Market Cap | Price 1D | Price 1M | Price 3M | Price 12M | EPS |
|---|---|---|---|---|---|---|
| $194M | $409M | XXX | XXX | XXX | XXX | $-1.52 |
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Sign UpAs of April 15, 2025, Stoke Therapeutics has market cap of $409M and EV of $194M.
Stoke Therapeutics's trades at 4.5x LTM EV/Revenue multiple, and -2.1x LTM EBITDA.
Analysts estimate Stoke Therapeutics's 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX
See valuation multiples for Stoke Therapeutics and 10K+ public comps| FY 2024 | FY 2025E | FY 2026E | FY 2027E | |
|---|---|---|---|---|
| EV | $194M | XXX | XXX | XXX |
| EV/Revenue | 5.3x | XXX | XXX | XXX |
| EV/EBITDA | -2.0x | XXX | XXX | XXX |
| P/E | -4.6x | XXX | XXX | XXX |
| P/E/Growth | n/a | XXX | XXX | XXX |
| EV/FCF | -2.2x | XXX | XXX | XXX |
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Access all public comps and forward-looking valuation multiples like EV/Revenue in 2025, based on equity research analyst estimates.
Sign UpStoke Therapeutics's NTM/LTM revenue growth is 41%
Stoke Therapeutics's revenue per employee for the last fiscal year averaged $0.3M, while opex per employee averaged $1.1M for the same period.
Over next 12 months, Stoke Therapeutics's ratio of sales and marketing spend to revenue is estimated to be XXX , while its R&D spend to revenue to be XXX .
Analysts estimate Stoke Therapeutics's 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX
See operational valuation multiples for Stoke Therapeutics and other 10K+ public comps| FY 2024 | NTM | FY 2025E | FY 2026E | FY 2027E | |
|---|---|---|---|---|---|
| Revenue Growth | 316% | XXX | XXX | XXX | XXX |
| EBITDA Margin | -271% | XXX | XXX | XXX | XXX |
| EBITDA Growth | -12% | XXX | XXX | XXX | XXX |
| Rule of 40 (SaaS-only) | -231% | XXX | XXX | XXX | XXX |
| Revenue per Employee | $0.3M | XXX | XXX | XXX | XXX |
| Opex per Employee | $1.1M | XXX | XXX | XXX | XXX |
| S&M Expenses to Revenue | n/a | XXX | XXX | XXX | XXX |
| G&A Expenses to Revenue | 133% | XXX | XXX | XXX | XXX |
| R&D Expenses to Revenue | 244% | XXX | XXX | XXX | XXX |
| Opex to Revenue | 377% | XXX | XXX | XXX | XXX |
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Benchmark public comps and private revenue and EBITDA valuation multiples across GRC software, cloud infrastructure, DevOps, online marketplaces and so much more!
| EV/Revenue | EV/EBITDA | |||||
|---|---|---|---|---|---|---|
| 2025E | 2026E | 2027E | 2025E | 2026E | 2027E | |
| Julphar | XXX | XXX | XXX | XXX | XXX | XXX |
| Benevolent AI | XXX | XXX | XXX | XXX | XXX | XXX |
| Galapagos | XXX | XXX | XXX | XXX | XXX | XXX |
| Pharming | XXX | XXX | XXX | XXX | XXX | XXX |
| Vivoryon Therapeutics | XXX | XXX | XXX | XXX | XXX | XXX |
| XXXXXXXX | XXX | XXX | XXX | XXX | XXX | XXX |
| XXXXXXXX | XXX | XXX | XXX | XXX | XXX | XXX |
Valuation data powered by FactSet, Inc.
Stoke Therapeutics acquired XXX companies to date.
Last acquisition by Stoke Therapeutics was XXXXXXXX, XXXXX XXXXX XXXXXX . Stoke Therapeutics acquired XXXXXXXX for XXX (EV/Revenue multiple of XXX ).
See M&A valuation multiples| Acquired Company | EV | EV/Revenue | EV/EBITDA |
|---|---|---|---|
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
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Sign Up| When was Stoke Therapeutics founded? | Stoke Therapeutics was founded in 2014. |
| Where is Stoke Therapeutics headquartered? | Stoke Therapeutics is headquartered in United States of America. |
| How many employees does Stoke Therapeutics have? | As of today, Stoke Therapeutics has 128 employees. |
| Who is the CEO of Stoke Therapeutics? | Stoke Therapeutics's CEO is Mr. Ian F. Smith. |
| Is Stoke Therapeutics publicy listed? | Yes, Stoke Therapeutics is a public company listed on NAS. |
| What is the stock symbol of Stoke Therapeutics? | Stoke Therapeutics trades under STOK ticker. |
| When did Stoke Therapeutics go public? | Stoke Therapeutics went public in 2019. |
| Who are competitors of Stoke Therapeutics? | Similar companies to Stoke Therapeutics include e.g. Julphar, Benevolent AI, Galapagos, Pharming. |
| What is the current market cap of Stoke Therapeutics? | Stoke Therapeutics's current market cap is $409M |
| What is the current revenue of Stoke Therapeutics? | Stoke Therapeutics's last 12-month revenue is $43.3M. |
| What is the current EBITDA of Stoke Therapeutics? | Stoke Therapeutics's last 12-month EBITDA is -$94.7M. |
| What is the current EV/Revenue multiple of Stoke Therapeutics? | Current revenue multiple of Stoke Therapeutics is 4.5x. |
| What is the current EV/EBITDA multiple of Stoke Therapeutics? | Current EBITDA multiple of Stoke Therapeutics is -2.1x. |
| What is the current revenue growth of Stoke Therapeutics? | Stoke Therapeutics revenue growth between 2023 and 2024 was 316%. |
| Is Stoke Therapeutics profitable? | Yes, Stoke Therapeutics is EBITDA-positive (as of the last 12 months). |
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