PYC Therapeutics - Public Comps and Valuation Multiples

PYC Therapeutics Overview

About PYC Therapeutics

PYC Therapeutics Ltd is an RNA therapeutics drug development company, leveraging a proprietary delivery platform to solve the challenges in RNA therapeutics - safe and effective delivery of the drug inside the cell. The company's principal business activity is of of drug development and progressing the company’s drug pipeline through preclinical and clinical development. Geographically, it operates only in Australia.

Founded

2001

HQ

Employees

Website

pyctx.com

Sectors

Drug Development & Therapeutics
Biopharmaceuticals
BioTech

Financials

LTM Revenue $14.5M

LTM EBITDA -$42.9M

EV

$357M

Valuation Multiples

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PYC Therapeutics Financials

As of September 2025, PYC Therapeutics reported last 12-month revenue of $14.5M and EBITDA of -$42.9M.

In the same period, PYC Therapeutics achieved -$38.0M in LTM net income.

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PYC Therapeutics P&L

In the most recent fiscal year, PYC Therapeutics reported EBITDA of -$32.8M.

PYC Therapeutics expects next 12-month revenue of XXX and NTM EBITDA of XXX

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	LTM	NTM	Last FY	FY 2025	FY 2026	FY 2027
Revenue	$14.5M	XXX	n/a	XXX	XXX	XXX
Gross Profit	n/a	XXX	n/a	XXX	XXX	XXX
Gross Margin	n/a	XXX	n/a	XXX	XXX	XXX
EBITDA	-$42.9M	XXX	-$32.8M	XXX	XXX	XXX
EBITDA Margin	-296%	XXX	n/a	XXX	XXX	XXX
EBIT	-$45.1M	XXX	-$49.4M	XXX	XXX	XXX
EBIT Margin	-311%	XXX	n/a	XXX	XXX	XXX
Net Profit	-$38.0M	XXX	-$32.8M	XXX	XXX	XXX
Net Margin	-262%	XXX	n/a	XXX	XXX	XXX
Net Debt	XXX	XXX	n/a	XXX	XXX	XXX

Financial data powered by Morningstar, Inc.

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Financial performance metrics for PYC Therapeutics including revenue, profitability, and margin analysis across different time periods. The company reported last twelve months revenue of $14.5M. EBITDA for the last twelve months was -$42.9M.
Financial Metric	Last Twelve Months (LTM)	Next Twelve Months (NTM)	Most Recent Fiscal Year	Current Fiscal Year (2025)	Next Fiscal Year (2026)	Two Years Forward (2027)
Total Revenue	$14.5M	Analyst estimates available to subscribers	n/a	Analyst estimates available to subscribers	Analyst estimates available to subscribers	Analyst estimates available to subscribers
Gross Profit	n/a	Analyst estimates available to subscribers	n/a	Analyst estimates available to subscribers	Analyst estimates available to subscribers	Analyst estimates available to subscribers
Gross Profit Margin	n/a	Analyst estimates available to subscribers	NaN% gross profit margin	Analyst estimates available to subscribers	Analyst estimates available to subscribers	Analyst estimates available to subscribers
EBITDA (Earnings Before Interest, Taxes, Depreciation, Amortization)	-$42.9M	Analyst estimates available to subscribers	-$32.8M	Analyst estimates available to subscribers	Analyst estimates available to subscribers	Analyst estimates available to subscribers
EBITDA Margin	-295.7% EBITDA margin	Analyst estimates available to subscribers	NaN% EBITDA margin	Analyst estimates available to subscribers	Analyst estimates available to subscribers	Analyst estimates available to subscribers
EBIT (Earnings Before Interest and Taxes)	-$45.1M	Analyst estimates available to subscribers	-$49.4M	Analyst estimates available to subscribers	Analyst estimates available to subscribers	Analyst estimates available to subscribers
EBIT Margin	-310.8% EBIT margin	Analyst estimates available to subscribers	n/a	Analyst estimates available to subscribers	Analyst estimates available to subscribers	Analyst estimates available to subscribers
Net Income (Net Profit)	-$38.0M	Analyst estimates available to subscribers	-$32.8M	Analyst estimates available to subscribers	Analyst estimates available to subscribers	Analyst estimates available to subscribers
Net Profit Margin	-261.9% net profit margin	Analyst estimates available to subscribers	NaN% net profit margin	Analyst estimates available to subscribers	Analyst estimates available to subscribers	Analyst estimates available to subscribers
Net Debt Position	Detailed debt information available to subscribers	Detailed debt information available to subscribers	n/a	Detailed debt information available to subscribers	Detailed debt information available to subscribers	Detailed debt information available to subscribers

Financial Performance Summary for PYC Therapeutics

This financial data table provides comprehensive performance metrics for PYC Therapeutics, a company based in Australia. The metrics include revenue, profitability measures, and operational efficiency indicators across multiple time periods.

Recent Performance Highlights

PYC Therapeutics generated $14.5M in revenue over the last twelve months.
The company achieved -$42.9M in EBITDA over the last twelve months.
Net income over the last twelve months reached -$38.0M.

Fiscal Year Performance

Fiscal year EBITDA was -$32.8M.
The company maintained a gross profit margin of NaN% in the most recent fiscal year.
EBITDA margin for the fiscal year was NaN%.
Net profit margin reached NaN% in the most recent fiscal year.

This financial data is sourced from Morningstar, Inc. and represents the most recent available information for PYC Therapeutics. Forward-looking estimates and detailed financial projections are available through our premium subscription service.

PYC Therapeutics Stock Performance

PYC Therapeutics has current market cap of AUD 700M (or $456M), and EV of AUD 548M (or $357M).

Market Cap Evolution

PYC Therapeutics Stock Data

As of October 17, 2025, PYC Therapeutics's stock price is AUD 1 (or $1).

See PYC Therapeutics trading valuation data

EV	Market Cap	Price 1D	Price 1M	Price 3M	Price 12M	EPS
$357M	$456M	XXX	XXX	XXX	XXX	$-0.07

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PYC Therapeutics Valuation Multiples

PYC Therapeutics's trades at n/a EV/Revenue multiple, and -12.5x EV/EBITDA.

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PYC Therapeutics Financial Valuation Multiples

As of October 17, 2025, PYC Therapeutics has market cap of $456M and EV of $357M.

Equity research analysts estimate PYC Therapeutics's 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX

PYC Therapeutics has a P/E ratio of -12.0x.

	LTM	NTM	Last FY	FY 2025	FY 2026	FY 2027
Market cap (current)	$456M	XXX	$456M	XXX	XXX	XXX
EV (current)	$357M	XXX	$357M	XXX	XXX	XXX
EV/Revenue	24.6x	XXX	n/a	XXX	XXX	XXX
EV/EBITDA	-8.3x	XXX	-12.5x	XXX	XXX	XXX
EV/EBIT	-7.9x	XXX	-8.0x	XXX	XXX	XXX
EV/Gross Profit	n/a	XXX	n/a	XXX	XXX	XXX
P/E	-12.0x	XXX	-15.9x	XXX	XXX	XXX
EV/FCF	-9.1x	XXX	-12.0x	XXX	XXX	XXX

Valuation data powered by FactSet, Inc. and Morningstar, Inc.

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PYC Therapeutics Margins & Growth Rates

PYC Therapeutics's last 12 month revenue growth is -17%

PYC Therapeutics's revenue per employee in the last FY averaged n/a, while opex per employee averaged $9.9M for the same period.

PYC Therapeutics's rule of 40 is unknown (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

PYC Therapeutics's rule of X is -339% (created by Bessemer, rule of X is another metric relevant for SaaS companies only, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

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PYC Therapeutics Operational Valuation Multiples

	LTM	NTM	Last FY	FY 2025	FY 2026	FY 2027
Revenue Growth	-17%	XXX	n/a	XXX	XXX	XXX
EBITDA Margin	-296%	XXX	n/a	XXX	XXX	XXX
EBITDA Growth	39%	XXX	n/a	XXX	XXX	XXX
Rule of 40	n/a	XXX	n/a	XXX	XXX	XXX
Bessemer Rule of X	XXX	XXX	-339%	XXX	XXX	XXX
Revenue per Employee	XXX	XXX	n/a	XXX	XXX	XXX
Opex per Employee	XXX	XXX	$9.9M	XXX	XXX	XXX
S&M Expenses to Revenue	XXX	XXX	n/a	XXX	XXX	XXX
G&A Expenses to Revenue	XXX	XXX	n/a	XXX	XXX	XXX
R&D Expenses to Revenue	XXX	XXX	n/a	XXX	XXX	XXX
Opex to Revenue	XXX	XXX	n/a	XXX	XXX	XXX

Valuation data powered by FactSet, Inc. and Morningstar, Inc.

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