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Prime Medicine Valuation Multiples

Discover revenue and EBITDA valuation multiples for Prime Medicine and similar public comparables like Pharming, Galapagos, and Vivoryon Therapeutics.

Prime Medicine Overview

About Prime Medicine

Prime Medicine Inc is a biotechnology company committed to delivering genetic therapies to address diseases by deploying gene editing technology, Prime Editing. The Prime Editing technology is a next-generation technology that can search and replace to restore normal genetic function in the genome and can treat a wide spectrum of diseases with high unmet medical needs and efficient and broad gene editing technology.


Founded

2019

HQ

United States of America
Employees

214

Financials

LTM Revenue $7.0M

LTM EBITDA -$182M

EV

$132M

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Prime Medicine Financials

Prime Medicine has a last 12-month revenue (LTM) of $7.0M and a last 12-month EBITDA of -$182M.

In the most recent fiscal year, Prime Medicine achieved revenue of $3.0M and an EBITDA of -$196M.

Prime Medicine expects next 12-month revenue of  XXX    and NTM EBITDA of  XXX

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Prime Medicine P&L

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue $7.0M XXX $3.0M XXX XXX XXX
Gross Profit $7.0M XXX n/a XXX XXX XXX
Gross Margin 100% XXX n/a XXX XXX XXX
EBITDA -$182M XXX -$196M XXX XXX XXX
EBITDA Margin -2605% XXX -6582% XXX XXX XXX
EBIT -$188M XXX -$202M XXX XXX XXX
EBIT Margin -2695% XXX -6787% XXX XXX XXX
Net Profit -$186M XXX -$196M XXX XXX XXX
Net Margin -2664% XXX -6567% XXX XXX XXX
Net Debt XXX XXX n/a XXX XXX XXX

Financial data powered by Morningstar, Inc.

Prime Medicine Stock Performance

As of May 30, 2025, Prime Medicine's stock price is $1.

Prime Medicine has current market cap of $155M, and EV of $132M.

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Prime Medicine Stock Data

EV Market Cap Price 1D Price 1M Price 3M Price 12M EPS
$132M $155M XXX XXX XXX XXX $-1.49

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Prime Medicine Valuation Multiples

As of May 30, 2025, Prime Medicine has market cap of $155M and EV of $132M.

Prime Medicine's trades at 44.4x EV/Revenue multiple, and -0.7x EV/EBITDA.

Equity research analysts estimate Prime Medicine's 2025E EV/Revenue multiple at  XXX and 2025E EV/EBITDA multiple at  XXX

Prime Medicine has a P/E ratio of -0.8x.

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Prime Medicine Financial Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Market cap (current) $155M XXX $155M XXX XXX XXX
EV (current) $132M XXX $132M XXX XXX XXX
EV/Revenue 18.9x XXX 44.4x XXX XXX XXX
EV/EBITDA -0.7x XXX -0.7x XXX XXX XXX
EV/EBIT -0.7x XXX -0.7x XXX XXX XXX
EV/Gross Profit 18.9x XXX n/a XXX XXX XXX
P/E -0.8x XXX -0.8x XXX XXX XXX
EV/FCF -1.0x XXX -1.0x XXX XXX XXX

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Prime Medicine Margins & Growth Rates

Prime Medicine's last 12 month revenue growth is 172%

Prime Medicine's revenue per employee in the last FY averaged $14K, while opex per employee averaged $1.0M for the same period.

Prime Medicine's rule of 40 is unknown (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Prime Medicine's rule of X is -2174% (created by Bessemer, rule of X is another metric relevant for SaaS companies only, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

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Prime Medicine Operational Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue Growth 172% XXX 207% XXX XXX XXX
EBITDA Margin -2605% XXX -6582% XXX XXX XXX
EBITDA Growth -13% XXX n/a XXX XXX XXX
Rule of 40 n/a XXX -6410% XXX XXX XXX
Bessemer Rule of X XXX XXX -2174% XXX XXX XXX
Revenue per Employee XXX XXX $14K XXX XXX XXX
Opex per Employee XXX XXX $1.0M XXX XXX XXX
S&M Expenses to Revenue XXX XXX n/a XXX XXX XXX
G&A Expenses to Revenue XXX XXX n/a XXX XXX XXX
R&D Expenses to Revenue XXX XXX 5206% XXX XXX XXX
Opex to Revenue XXX XXX 6887% XXX XXX XXX

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Prime Medicine Public Comps

See public comps and valuation multiples for Drug Development & Therapeutics and Genomics & Personalized Medicine comps
EV/Revenue EV/EBITDA
2025E 2026E 2027E 2025E 2026E 2027E
Julphar XXX XXX XXX XXX XXX XXX
Benevolent AI XXX XXX XXX XXX XXX XXX
Galapagos XXX XXX XXX XXX XXX XXX
Pharming XXX XXX XXX XXX XXX XXX
Vivoryon Therapeutics XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX

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Prime Medicine M&A and Investment Activity

Prime Medicine acquired  XXX companies to date.

Last acquisition by Prime Medicine was  XXXXXXXX, XXXXX XXXXX XXXXXX . Prime Medicine acquired  XXXXXXXX for  XXX (EV/Revenue multiple of  XXX ).

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Latest Acquisitions by Prime Medicine

Acquired Company EV EV/Revenue EV/EBITDA
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX

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About Prime Medicine

When was Prime Medicine founded? Prime Medicine was founded in 2019.
Where is Prime Medicine headquartered? Prime Medicine is headquartered in United States of America.
How many employees does Prime Medicine have? As of today, Prime Medicine has 214 employees.
Who is the CEO of Prime Medicine? Prime Medicine's CEO is Dr. Allan Reine, M.D..
Is Prime Medicine publicy listed? Yes, Prime Medicine is a public company listed on NAS.
What is the stock symbol of Prime Medicine? Prime Medicine trades under PRME ticker.
When did Prime Medicine go public? Prime Medicine went public in 2022.
Who are competitors of Prime Medicine? Similar companies to Prime Medicine include e.g. Julphar, Benevolent AI, Galapagos, Pharming.
What is the current market cap of Prime Medicine? Prime Medicine's current market cap is $155M
What is the current revenue of Prime Medicine? Prime Medicine's last 12 months revenue is $7.0M.
What is the current revenue growth of Prime Medicine? Prime Medicine revenue growth (NTM/LTM) is 172%.
What is the current EV/Revenue multiple of Prime Medicine? Current revenue multiple of Prime Medicine is 18.9x.
Is Prime Medicine profitable? Yes, Prime Medicine is EBITDA-positive (as of the last 12 months).
What is the current EBITDA of Prime Medicine? Prime Medicine's last 12 months EBITDA is -$182M.
What is Prime Medicine's EBITDA margin? Prime Medicine's last 12 months EBITDA margin is -2605%.
What is the current EV/EBITDA multiple of Prime Medicine? Current EBITDA multiple of Prime Medicine is -0.7x.
What is the current FCF of Prime Medicine? Prime Medicine's last 12 months FCF is -$138M.
What is Prime Medicine's FCF margin? Prime Medicine's last 12 months FCF margin is -1981%.
What is the current EV/FCF multiple of Prime Medicine? Current FCF multiple of Prime Medicine is -1.0x.

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