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Personalis Valuation Multiples

Discover revenue and EBITDA valuation multiples for Personalis and similar public comparables like Genus, 4basebio, and Epigenomics.

Personalis Overview

About Personalis

Personalis Inc is a provider of genomic sequencing and analytics solutions to support the development of personalized cancer vaccines and other next-generation cancer immunotherapies. It has one segment, the sale of sequencing and data analysis services. Its products include ImmunoID NeXT, NeXT Personal, NeXT Dx Test, and other pharma research solutions.


Founded

2011

HQ

United States of America
Employees

229

Website

personalis.com

Financials

LTM Revenue $84.1M

LTM EBITDA -$68.6M

EV

$268M

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Personalis Financials

Personalis has a last 12-month revenue (LTM) of $84.1M and a last 12-month EBITDA of -$68.6M.

In the most recent fiscal year, Personalis achieved revenue of $84.6M and an EBITDA of -$70.3M.

Personalis expects next 12-month revenue of  XXX    and NTM EBITDA of  XXX

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Personalis P&L

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue $84.1M XXX $84.6M XXX XXX XXX
Gross Profit $23.8M XXX $26.8M XXX XXX XXX
Gross Margin 28% XXX 32% XXX XXX XXX
EBITDA -$68.6M XXX -$70.3M XXX XXX XXX
EBITDA Margin -82% XXX -83% XXX XXX XXX
EBIT -$77.0M XXX -$68.3M XXX XXX XXX
EBIT Margin -92% XXX -81% XXX XXX XXX
Net Profit -$82.1M XXX -$81.3M XXX XXX XXX
Net Margin -98% XXX -96% XXX XXX XXX
Net Debt XXX XXX n/a XXX XXX XXX

Financial data powered by Morningstar, Inc.

Personalis Stock Performance

As of May 30, 2025, Personalis's stock price is $5.

Personalis has current market cap of $409M, and EV of $268M.

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Personalis Stock Data

EV Market Cap Price 1D Price 1M Price 3M Price 12M EPS
$268M $409M XXX XXX XXX XXX $-1.19

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Personalis Valuation Multiples

As of May 30, 2025, Personalis has market cap of $409M and EV of $268M.

Personalis's trades at 3.2x EV/Revenue multiple, and -3.8x EV/EBITDA.

Equity research analysts estimate Personalis's 2025E EV/Revenue multiple at  XXX and 2025E EV/EBITDA multiple at  XXX

Personalis has a P/E ratio of -5.0x.

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Personalis Financial Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Market cap (current) $409M XXX $409M XXX XXX XXX
EV (current) $268M XXX $268M XXX XXX XXX
EV/Revenue 3.2x XXX 3.2x XXX XXX XXX
EV/EBITDA -3.9x XXX -3.8x XXX XXX XXX
EV/EBIT -3.5x XXX -3.9x XXX XXX XXX
EV/Gross Profit 11.2x XXX n/a XXX XXX XXX
P/E -5.0x XXX -5.0x XXX XXX XXX
EV/FCF n/a XXX -5.7x XXX XXX XXX

Valuation data powered by FactSet, Inc. and Morningstar, Inc.

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Personalis Margins & Growth Rates

Personalis's last 12 month revenue growth is 10%

Personalis's revenue per employee in the last FY averaged $0.4M, while opex per employee averaged $0.4M for the same period.

Personalis's rule of 40 is -122% (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Personalis's rule of X is -57% (created by Bessemer, rule of X is another metric relevant for SaaS companies only, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

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Personalis Operational Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue Growth 10% XXX 11% XXX XXX XXX
EBITDA Margin -82% XXX -83% XXX XXX XXX
EBITDA Growth 16% XXX n/a XXX XXX XXX
Rule of 40 -122% XXX -73% XXX XXX XXX
Bessemer Rule of X XXX XXX -57% XXX XXX XXX
Revenue per Employee XXX XXX $0.4M XXX XXX XXX
Opex per Employee XXX XXX $0.4M XXX XXX XXX
S&M Expenses to Revenue XXX XXX n/a XXX XXX XXX
G&A Expenses to Revenue XXX XXX n/a XXX XXX XXX
R&D Expenses to Revenue XXX XXX 58% XXX XXX XXX
Opex to Revenue XXX XXX 112% XXX XXX XXX

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Personalis Public Comps

See public comps and valuation multiples for Genomics & Personalized Medicine and Bioinformatics comps
EV/Revenue EV/EBITDA
2025E 2026E 2027E 2025E 2026E 2027E
EZZ Life Science XXX XXX XXX XXX XXX XXX
Epigenomics XXX XXX XXX XXX XXX XXX
ToolGen XXX XXX XXX XXX XXX XXX
4basebio XXX XXX XXX XXX XXX XXX
Genus XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX

Valuation data powered by FactSet, Inc.

Personalis M&A and Investment Activity

Personalis acquired  XXX companies to date.

Last acquisition by Personalis was  XXXXXXXX, XXXXX XXXXX XXXXXX . Personalis acquired  XXXXXXXX for  XXX (EV/Revenue multiple of  XXX ).

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Latest Acquisitions by Personalis

Acquired Company EV EV/Revenue EV/EBITDA
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX

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About Personalis

When was Personalis founded? Personalis was founded in 2011.
Where is Personalis headquartered? Personalis is headquartered in United States of America.
How many employees does Personalis have? As of today, Personalis has 229 employees.
Who is the CEO of Personalis? Personalis's CEO is Mr. Christopher Hall.
Is Personalis publicy listed? Yes, Personalis is a public company listed on NAS.
What is the stock symbol of Personalis? Personalis trades under PSNL ticker.
When did Personalis go public? Personalis went public in 2019.
Who are competitors of Personalis? Similar companies to Personalis include e.g. EZZ Life Science, Epigenomics, ToolGen, 4basebio.
What is the current market cap of Personalis? Personalis's current market cap is $409M
What is the current revenue of Personalis? Personalis's last 12 months revenue is $84.1M.
What is the current revenue growth of Personalis? Personalis revenue growth (NTM/LTM) is 10%.
What is the current EV/Revenue multiple of Personalis? Current revenue multiple of Personalis is 3.2x.
Is Personalis profitable? Yes, Personalis is EBITDA-positive (as of the last 12 months).
What is the current EBITDA of Personalis? Personalis's last 12 months EBITDA is -$68.6M.
What is Personalis's EBITDA margin? Personalis's last 12 months EBITDA margin is -82%.
What is the current EV/EBITDA multiple of Personalis? Current EBITDA multiple of Personalis is -3.9x.

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