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OPKO Health Valuation Multiples

Discover revenue and EBITDA valuation multiples for OPKO Health and similar public comparables like Chabiotech, SELLAS Life Sciences, Hyundai Bioscience, Sana Biotechnology and more.

OPKO Health Overview

About OPKO Health

OPKO Health Inc is a diversified biotechnology company that operates pharmaceutical and diagnostic development programs. Its segments include pharmaceutical and diagnostics. The Pharmaceutical segment consists of its pharmaceutical operations in Chile, Mexico, Ireland, Israel, Spain, Ecuador, France, the United States, and its pharmaceutical research and development operations. The Diagnostics segment consists of clinical and genomics laboratory operations through BioReference and point-of-care operations. It generates the majority of its revenue from the Diagnostics segment.


Founded

1991

HQ

United States

Employees

3.0K

Website

opko.com

Financials (LTM)

Revenue: $590M
EBITDA: ($124M)

EV

$969M

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OPKO Health Financials

OPKO Health reported last 12-month revenue of $590M and negative EBITDA of ($124M).

In the same LTM period, OPKO Health generated $262M in gross profit, ($124M) in EBITDA losses, and had net loss of ($222M).

Revenue (LTM)


OPKO Health P&L

In the most recent fiscal year, OPKO Health reported revenue of $607M and EBITDA of ($41M).

OPKO Health expects next 12-month revenue of XXX and NTM EBITDA of XXX

See OPKO Health forward-looking valuation multiples
LTMNTMLast FYFY 2026FY 2027FY 2028
Revenue$590MXXX$607MXXXXXXXXX
Gross Profit$262MXXX$206MXXXXXXXXX
Gross Margin44%XXX34%XXXXXXXXX
EBITDA($124M)XXX($41M)XXXXXXXXX
EBITDA Margin(21%)XXX(7%)XXXXXXXXX
EBIT Margin(24%)XXX(19%)XXXXXXXXX
Net Profit($222M)XXX($226M)XXXXXXXXX
Net Margin(38%)XXX(37%)XXXXXXXXX

Financial data powered by Morningstar, Inc.

OPKO Health Stock Performance

OPKO Health has current market cap of $941M, and enterprise value of $969M.

Market Cap Evolution


OPKO Health's stock price is $1.24.

See OPKO Health trading valuation data
EVMarket CapPrice 1DPrice 1MPrice 3MPrice 12MEPS
$969M$941M0.0%XXXXXXXXX$-0.30

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OPKO Health Valuation Multiples

OPKO Health trades at 1.6x EV/Revenue multiple, and (7.8x) EV/EBITDA.

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EV / Revenue (LTM)


OPKO Health Financial Valuation Multiples

As of April 20, 2026, OPKO Health has market cap of $941M and EV of $969M.

Equity research analysts estimate OPKO Health's 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX

OPKO Health has a P/E ratio of (4.2x).

LTMNTMLast FYFY 2026FY 2027FY 2028
Market cap (current)$941MXXX$941MXXXXXXXXX
EV (current)$969MXXX$969MXXXXXXXXX
EV/Revenue1.6xXXX1.6xXXXXXXXXX
EV/EBITDA(7.8x)XXX(23.5x)XXXXXXXXX
EV/EBIT(6.9x)XXX(8.3x)XXXXXXXXX
EV/Gross Profit3.7xXXX4.7xXXXXXXXXX
P/E(4.2x)XXX(4.2x)XXXXXXXXX
EV/FCF(7.7x)XXX(6.9x)XXXXXXXXX

Valuation data powered by FactSet, Inc. and Morningstar, Inc.

Verified OPKO Health Valuation Multiples

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OPKO Health Margins & Growth Rates

OPKO Health's revenue in the last 12 month declined by (5%).

OPKO Health's revenue per employee in the last FY averaged $0.2M, while opex per employee averaged $0.1M for the same period.

OPKO Health's rule of 40 is (31%) (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

OPKO Health's rule of X is (45%) (created by Bessemer, rule of X is another metric to measure SaaS companies, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

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OPKO Health Operational Valuation Multiples

LTMNTMLast FYFY 2026FY 2027FY 2028
Revenue Growth(5%)XXX(9%)XXXXXXXXX
EBITDA Margin(21%)XXX(7%)XXXXXXXXX
EBITDA Growth(13%)XXX197%XXXXXXXXX
Rule of 40—XXX(31%)XXXXXXXXX
Bessemer Rule of X—XXX(45%)XXXXXXXXX
Revenue per Employee—XXX$0.2MXXXXXXXXX
Opex per Employee—XXX$0.1MXXXXXXXXX
R&D Expenses to Revenue21%XXX20%XXXXXXXXX
Opex to Revenue—XXX70%XXXXXXXXX

Valuation data powered by FactSet, Inc. and Morningstar, Inc.

Valuation Multiples Across 230+ Verticals

OPKO Health Public Comps

See public comps and valuation multiples for other Biopharmaceuticals and Diagnostics & Genomics comps.

EV/RevenueEV/EBITDA
LTM2026E2027ELTM2026E2027E
OPKO HealthXXXXXXXXXXXXXXXXXX
ChabiotechXXXXXXXXXXXXXXXXXX
SELLAS Life SciencesXXXXXXXXXXXXXXXXXX
Hyundai BioscienceXXXXXXXXXXXXXXXXXX
Sana BiotechnologyXXXXXXXXXXXXXXXXXX
MeiraGTxXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX

Valuation data powered by FactSet, Inc.

OPKO Health M&A Activity

OPKO Health acquired XXX companies to date.

Last acquisition by OPKO Health was on XXXXXXXX, XXXXX. OPKO Health acquired XXXXXXXX for XXX (EV/Revenue multiple of XXX).

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Latest Acquisitions by OPKO Health

Acquired CompanyValuationEV/RevenueEV/EBITDA
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX

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OPKO Health Investment Activity

OPKO Health invested in XXX companies to date.

OPKO Health made its latest investment on XXXXXXXX, XXXXX. OPKO Health invested in XXXXXXXX for XXX (EV/Revenue multiple of XXX).

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Latest Investments by OPKO Health

CompanyValuationEV/RevenueEV/EBITDA
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX

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About OPKO Health

When was OPKO Health founded?OPKO Health was founded in 1991.
Where is OPKO Health headquartered?OPKO Health is headquartered in United States.
How many employees does OPKO Health have?As of today, OPKO Health has over 3K employees.
Who is the CEO of OPKO Health?OPKO Health's CEO is Phillip Frost.
Is OPKO Health publicly listed?Yes, OPKO Health is a public company listed on Nasdaq.
What is the stock symbol of OPKO Health?OPKO Health trades under OPK ticker.
When did OPKO Health go public?OPKO Health went public in 1995.
Who are competitors of OPKO Health?OPKO Health main competitors are Chabiotech, SELLAS Life Sciences, Hyundai Bioscience, Sana Biotechnology.
What is the current market cap of OPKO Health?OPKO Health's current market cap is $941M.
What is the current revenue of OPKO Health?OPKO Health's last 12 months revenue is $590M.
What is the current revenue growth of OPKO Health?OPKO Health revenue growth (NTM/LTM) is (5%).
What is the current EV/Revenue multiple of OPKO Health?Current revenue multiple of OPKO Health is 1.6x.
Is OPKO Health profitable?No, OPKO Health is not profitable.
What is the current EBITDA of OPKO Health?OPKO Health has negative EBITDA and is not profitable.
What is OPKO Health's EBITDA margin?OPKO Health's last 12 months EBITDA margin is (21%).
What is the current EV/EBITDA multiple of OPKO Health?Current EBITDA multiple of OPKO Health is (7.8x).
What is the current FCF of OPKO Health?OPKO Health's last 12 months FCF is ($126M).
What is OPKO Health's FCF margin?OPKO Health's last 12 months FCF margin is (21%).
What is the current EV/FCF multiple of OPKO Health?Current FCF multiple of OPKO Health is (7.7x).

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