🚀 VC round data is live in beta, check it out!
- Public Comps
- OPKO Health
OPKO Health Valuation Multiples
Discover revenue and EBITDA valuation multiples for OPKO Health and similar public comparables like Chabiotech, SELLAS Life Sciences, Hyundai Bioscience, Sana Biotechnology and more.
OPKO Health Overview
About OPKO Health
OPKO Health Inc is a diversified biotechnology company that operates pharmaceutical and diagnostic development programs. Its segments include pharmaceutical and diagnostics. The Pharmaceutical segment consists of its pharmaceutical operations in Chile, Mexico, Ireland, Israel, Spain, Ecuador, France, the United States, and its pharmaceutical research and development operations. The Diagnostics segment consists of clinical and genomics laboratory operations through BioReference and point-of-care operations. It generates the majority of its revenue from the Diagnostics segment.
Founded
1991
HQ

Employees
3.0K
Website
Financials (LTM)
EV
$969M
OPKO Health Financials
OPKO Health reported last 12-month revenue of $590M and negative EBITDA of ($124M).
In the same LTM period, OPKO Health generated $262M in gross profit, ($124M) in EBITDA losses, and had net loss of ($222M).
Revenue (LTM)
OPKO Health P&L
In the most recent fiscal year, OPKO Health reported revenue of $607M and EBITDA of ($41M).
OPKO Health expects next 12-month revenue of XXX and NTM EBITDA of XXX
| LTM | NTM | Last FY | FY 2026 | FY 2027 | FY 2028 | |
|---|---|---|---|---|---|---|
| Revenue | $590M | XXX | $607M | XXX | XXX | XXX |
| Gross Profit | $262M | XXX | $206M | XXX | XXX | XXX |
| Gross Margin | 44% | XXX | 34% | XXX | XXX | XXX |
| EBITDA | ($124M) | XXX | ($41M) | XXX | XXX | XXX |
| EBITDA Margin | (21%) | XXX | (7%) | XXX | XXX | XXX |
| EBIT Margin | (24%) | XXX | (19%) | XXX | XXX | XXX |
| Net Profit | ($222M) | XXX | ($226M) | XXX | XXX | XXX |
| Net Margin | (38%) | XXX | (37%) | XXX | XXX | XXX |
Financial data powered by Morningstar, Inc.
OPKO Health Stock Performance
OPKO Health has current market cap of $941M, and enterprise value of $969M.
Market Cap Evolution
OPKO Health's stock price is $1.24.
| EV | Market Cap | Price 1D | Price 1M | Price 3M | Price 12M | EPS |
|---|---|---|---|---|---|---|
| $969M | $941M | 0.0% | XXX | XXX | XXX | $-0.30 |
Benchmark Trading Valuation Multiples by Industry
Sign up to access valuation multiples like growth-adjusted P/E, Rule of 40, next 12-month EV/Revenue, EBITDA multiples by industry, consensus analyst estimates and many more.
Start Free TrialOPKO Health Valuation Multiples
OPKO Health trades at 1.6x EV/Revenue multiple, and (7.8x) EV/EBITDA.
EV / Revenue (LTM)
OPKO Health Financial Valuation Multiples
As of April 20, 2026, OPKO Health has market cap of $941M and EV of $969M.
Equity research analysts estimate OPKO Health's 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX
OPKO Health has a P/E ratio of (4.2x).
| LTM | NTM | Last FY | FY 2026 | FY 2027 | FY 2028 | |
|---|---|---|---|---|---|---|
| Market cap (current) | $941M | XXX | $941M | XXX | XXX | XXX |
| EV (current) | $969M | XXX | $969M | XXX | XXX | XXX |
| EV/Revenue | 1.6x | XXX | 1.6x | XXX | XXX | XXX |
| EV/EBITDA | (7.8x) | XXX | (23.5x) | XXX | XXX | XXX |
| EV/EBIT | (6.9x) | XXX | (8.3x) | XXX | XXX | XXX |
| EV/Gross Profit | 3.7x | XXX | 4.7x | XXX | XXX | XXX |
| P/E | (4.2x) | XXX | (4.2x) | XXX | XXX | XXX |
| EV/FCF | (7.7x) | XXX | (6.9x) | XXX | XXX | XXX |
Valuation data powered by FactSet, Inc. and Morningstar, Inc.
Verified OPKO Health Valuation Multiples
Access all public comps and forward-looking valuation multiples like EV/Revenue in 2027, based on consensus analyst estimates. Powered by FactSet and Morningstar.


OPKO Health Margins & Growth Rates
OPKO Health's revenue in the last 12 month declined by (5%).
OPKO Health's revenue per employee in the last FY averaged $0.2M, while opex per employee averaged $0.1M for the same period.
OPKO Health's rule of 40 is (31%) (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).
OPKO Health's rule of X is (45%) (created by Bessemer, rule of X is another metric to measure SaaS companies, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).
OPKO Health Operational Valuation Multiples
| LTM | NTM | Last FY | FY 2026 | FY 2027 | FY 2028 | |
|---|---|---|---|---|---|---|
| Revenue Growth | (5%) | XXX | (9%) | XXX | XXX | XXX |
| EBITDA Margin | (21%) | XXX | (7%) | XXX | XXX | XXX |
| EBITDA Growth | (13%) | XXX | 197% | XXX | XXX | XXX |
| Rule of 40 | — | XXX | (31%) | XXX | XXX | XXX |
| Bessemer Rule of X | — | XXX | (45%) | XXX | XXX | XXX |
| Revenue per Employee | — | XXX | $0.2M | XXX | XXX | XXX |
| Opex per Employee | — | XXX | $0.1M | XXX | XXX | XXX |
| R&D Expenses to Revenue | 21% | XXX | 20% | XXX | XXX | XXX |
| Opex to Revenue | — | XXX | 70% | XXX | XXX | XXX |
Valuation data powered by FactSet, Inc. and Morningstar, Inc.
OPKO Health Public Comps
See public comps and valuation multiples for other Biopharmaceuticals and Diagnostics & Genomics comps.
| EV/Revenue | EV/EBITDA | |||||
|---|---|---|---|---|---|---|
| LTM | 2026E | 2027E | LTM | 2026E | 2027E | |
| OPKO Health | XXX | XXX | XXX | XXX | XXX | XXX |
| Chabiotech | XXX | XXX | XXX | XXX | XXX | XXX |
| SELLAS Life Sciences | XXX | XXX | XXX | XXX | XXX | XXX |
| Hyundai Bioscience | XXX | XXX | XXX | XXX | XXX | XXX |
| Sana Biotechnology | XXX | XXX | XXX | XXX | XXX | XXX |
| MeiraGTx | XXX | XXX | XXX | XXX | XXX | XXX |
| XXXXXXXX | XXX | XXX | XXX | XXX | XXX | XXX |
| XXXXXXXX | XXX | XXX | XXX | XXX | XXX | XXX |
Valuation data powered by FactSet, Inc.
OPKO Health M&A Activity
OPKO Health acquired XXX companies to date.
Last acquisition by OPKO Health was on XXXXXXXX, XXXXX. OPKO Health acquired XXXXXXXX for XXX (EV/Revenue multiple of XXX).
Latest Acquisitions by OPKO Health
| Acquired Company | Valuation | EV/Revenue | EV/EBITDA |
|---|---|---|---|
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
Get Verified M&A Valuation Multiples
Sign up to see revenue and EBITDA valuation multiples for 150K+ M&A deals.
Start Free TrialOPKO Health Investment Activity
OPKO Health invested in XXX companies to date.
OPKO Health made its latest investment on XXXXXXXX, XXXXX. OPKO Health invested in XXXXXXXX for XXX (EV/Revenue multiple of XXX).
Latest Investments by OPKO Health
| Company | Valuation | EV/Revenue | EV/EBITDA |
|---|---|---|---|
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples
Sign up to see data on 350K+ funding rounds and disclosed revenue and EBITDA valuation multiples, from seed, through growth stage, to pre-IPO.
Start Free TrialAbout OPKO Health
| When was OPKO Health founded? | OPKO Health was founded in 1991. |
| Where is OPKO Health headquartered? | OPKO Health is headquartered in United States. |
| How many employees does OPKO Health have? | As of today, OPKO Health has over 3K employees. |
| Who is the CEO of OPKO Health? | OPKO Health's CEO is Phillip Frost. |
| Is OPKO Health publicly listed? | Yes, OPKO Health is a public company listed on Nasdaq. |
| What is the stock symbol of OPKO Health? | OPKO Health trades under OPK ticker. |
| When did OPKO Health go public? | OPKO Health went public in 1995. |
| Who are competitors of OPKO Health? | OPKO Health main competitors are Chabiotech, SELLAS Life Sciences, Hyundai Bioscience, Sana Biotechnology. |
| What is the current market cap of OPKO Health? | OPKO Health's current market cap is $941M. |
| What is the current revenue of OPKO Health? | OPKO Health's last 12 months revenue is $590M. |
| What is the current revenue growth of OPKO Health? | OPKO Health revenue growth (NTM/LTM) is (5%). |
| What is the current EV/Revenue multiple of OPKO Health? | Current revenue multiple of OPKO Health is 1.6x. |
| Is OPKO Health profitable? | No, OPKO Health is not profitable. |
| What is the current EBITDA of OPKO Health? | OPKO Health has negative EBITDA and is not profitable. |
| What is OPKO Health's EBITDA margin? | OPKO Health's last 12 months EBITDA margin is (21%). |
| What is the current EV/EBITDA multiple of OPKO Health? | Current EBITDA multiple of OPKO Health is (7.8x). |
| What is the current FCF of OPKO Health? | OPKO Health's last 12 months FCF is ($126M). |
| What is OPKO Health's FCF margin? | OPKO Health's last 12 months FCF margin is (21%). |
| What is the current EV/FCF multiple of OPKO Health? | Current FCF multiple of OPKO Health is (7.7x). |
Start Your
Free Trial Today
Try Multiples for free for 3 days. Got questions or need a demo? Schedule a call with us below.