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Metsera Valuation Multiples

Discover revenue and EBITDA valuation multiples for Metsera and similar public comparables like Vivoryon Therapeutics, Armata Pharmaceuticals, and Pharming.

Metsera Overview

About Metsera

Metsera Inc is a clinical-stage biotechnology company developing next-generation injectable and oral nutrient-stimulated hormone (NuSH) analog peptides to treat obesity, overweight, and related conditions. The Company has developed and is implementing proprietary methods and platform technologies to advance a broad, scalable, and combinable portfolio of injectable and oral NuSH analog peptides with the potential to address not only the limitations of approved therapies but also many of the anticipated limitations of next-generation therapies in development. The Company uses its proprietary MINT peptide library of NuSH analog peptides alongside its Half-life Augmentation by Lipid Optimization half-life extending platform.


Founded

2022

HQ

United States of America
Employees

81

Website

metsera.com

Financials

Last FY Revenue n/a

Last FY EBITDA -$218M

EV

$2.2B

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Metsera Financials

In the most recent fiscal year, Metsera achieved revenue of n/a and an EBITDA of -$218M.

Metsera expects next 12-month revenue of  XXX    and NTM EBITDA of  XXX

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Metsera P&L

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue n/a XXX n/a XXX XXX XXX
Gross Profit n/a XXX n/a XXX XXX XXX
Gross Margin n/a XXX n/a XXX XXX XXX
EBITDA n/a XXX -$218M XXX XXX XXX
EBITDA Margin n/a XXX n/a XXX XXX XXX
EBIT -$256M XXX -$134M XXX XXX XXX
EBIT Margin n/a XXX n/a XXX XXX XXX
Net Profit -$241M XXX -$209M XXX XXX XXX
Net Margin n/a XXX n/a XXX XXX XXX
Net Debt XXX XXX n/a XXX XXX XXX

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Metsera Stock Performance

As of May 30, 2025, Metsera's stock price is $27.

Metsera has current market cap of $2.8B, and EV of $2.2B.

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Metsera Stock Data

EV Market Cap Price 1D Price 1M Price 3M Price 12M EPS
$2.2B $2.8B XXX XXX XXX XXX $-9.65

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Metsera Valuation Multiples

As of May 30, 2025, Metsera has market cap of $2.8B and EV of $2.2B.

Metsera's trades at n/a EV/Revenue multiple, and -10.2x EV/EBITDA.

Equity research analysts estimate Metsera's 2025E EV/Revenue multiple at  XXX and 2025E EV/EBITDA multiple at  XXX

Metsera has a P/E ratio of -11.7x.

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Metsera Financial Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Market cap (current) $2.8B XXX $2.8B XXX XXX XXX
EV (current) $2.2B XXX $2.2B XXX XXX XXX
EV/Revenue n/a XXX n/a XXX XXX XXX
EV/EBITDA n/a XXX -10.2x XXX XXX XXX
EV/EBIT -8.7x XXX -16.6x XXX XXX XXX
EV/Gross Profit n/a XXX n/a XXX XXX XXX
P/E -11.7x XXX -13.4x XXX XXX XXX
EV/FCF n/a XXX -22.3x XXX XXX XXX

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Metsera Margins & Growth Rates

Metsera's revenue per employee in the last FY averaged n/a, while opex per employee averaged $1.7M for the same period.

Metsera's rule of 40 is unknown (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Metsera's rule of X is n/a (created by Bessemer, rule of X is another metric relevant for SaaS companies only, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

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Metsera Operational Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue Growth n/a XXX n/a XXX XXX XXX
EBITDA Margin n/a XXX n/a XXX XXX XXX
EBITDA Growth n/a XXX n/a XXX XXX XXX
Rule of 40 n/a XXX n/a XXX XXX XXX
Bessemer Rule of X XXX XXX n/a XXX XXX XXX
Revenue per Employee XXX XXX n/a XXX XXX XXX
Opex per Employee XXX XXX $1.7M XXX XXX XXX
S&M Expenses to Revenue XXX XXX n/a XXX XXX XXX
G&A Expenses to Revenue XXX XXX n/a XXX XXX XXX
R&D Expenses to Revenue XXX XXX n/a XXX XXX XXX
Opex to Revenue XXX XXX n/a XXX XXX XXX

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Metsera Public Comps

See public comps and valuation multiples for Biopharmaceuticals and Drug Development & Therapeutics comps
EV/Revenue EV/EBITDA
2025E 2026E 2027E 2025E 2026E 2027E
Julphar XXX XXX XXX XXX XXX XXX
Galapagos XXX XXX XXX XXX XXX XXX
Pharming XXX XXX XXX XXX XXX XXX
Vivoryon Therapeutics XXX XXX XXX XXX XXX XXX
Armata Pharmaceuticals XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX

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Metsera M&A and Investment Activity

Metsera acquired  XXX companies to date.

Last acquisition by Metsera was  XXXXXXXX, XXXXX XXXXX XXXXXX . Metsera acquired  XXXXXXXX for  XXX (EV/Revenue multiple of  XXX ).

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Latest Acquisitions by Metsera

Acquired Company EV EV/Revenue EV/EBITDA
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX

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About Metsera

When was Metsera founded? Metsera was founded in 2022.
Where is Metsera headquartered? Metsera is headquartered in United States of America.
How many employees does Metsera have? As of today, Metsera has 81 employees.
Who is the CEO of Metsera? Metsera's CEO is Mr. Christopher Whitten Bernard.
Is Metsera publicy listed? Yes, Metsera is a public company listed on NAS.
What is the stock symbol of Metsera? Metsera trades under MTSR ticker.
When did Metsera go public? Metsera went public in 2025.
Who are competitors of Metsera? Similar companies to Metsera include e.g. Julphar, Galapagos, Pharming, Vivoryon Therapeutics.
What is the current market cap of Metsera? Metsera's current market cap is $2.8B
Is Metsera profitable? Yes, Metsera is EBITDA-positive (as of the last 12 months).

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