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Lexicon Pharmaceuticals Valuation Multiples

Discover revenue and EBITDA valuation multiples for Lexicon Pharmaceuticals and similar public comparables like TTY Biopharm, uniQure, Ocugen, Luzhu Biotech and more.

Lexicon Pharmaceuticals Overview

About Lexicon Pharmaceuticals

Lexicon Pharmaceuticals Inc is a biopharmaceutical company. It is engaged in the discovery, development, and commercialization of pharmaceutical products for the treatment of human diseases. Some of its drug candidates are LX9211, an orally-delivered small molecule drug candidate, also developing LX9851, an orally-delivered small molecule drug candidate, as a treatment for obesity and associated cardiometabolic.


Founded

1995

HQ

United States

Employees

103

Financials (LTM)

Revenue: $46M
EBITDA: ($53M)

EV

$592M

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Lexicon Pharmaceuticals Financials

Lexicon Pharmaceuticals reported last 12-month revenue of $46M and negative EBITDA of ($53M).

In the same LTM period, Lexicon Pharmaceuticals generated $46M in gross profit, ($53M) in EBITDA losses, and had net loss of ($55M).

Revenue (LTM)


Lexicon Pharmaceuticals P&L

In the most recent fiscal year, Lexicon Pharmaceuticals reported revenue of $50M and EBITDA of ($41M).

Lexicon Pharmaceuticals expects next 12-month revenue of XXX and NTM EBITDA of XXX

See Lexicon Pharmaceuticals forward-looking valuation multiples
LTMNTMLast FYFY 2026FY 2027FY 2028
Revenue$46MXXX$50MXXXXXXXXX
Gross Profit$46MXXX$50MXXXXXXXXX
Gross Margin99%XXX99%XXXXXXXXX
EBITDA($53M)XXX($41M)XXXXXXXXX
EBITDA Margin(115%)XXX(83%)XXXXXXXXX
EBIT Margin(116%)XXX(98%)XXXXXXXXX
Net Profit($55M)XXX($50M)XXXXXXXXX
Net Margin(119%)XXX(101%)XXXXXXXXX
Net Debt——$20MXXXXXXXXX

Financial data powered by Morningstar, Inc.

Lexicon Pharmaceuticals Stock Performance

Lexicon Pharmaceuticals has current market cap of $650M, and enterprise value of $592M.

Market Cap Evolution


Lexicon Pharmaceuticals' stock price is $1.56.

See Lexicon Pharmaceuticals trading valuation data
EVMarket CapPrice 1DPrice 1MPrice 3MPrice 12MEPS
$592M$650M0.0%XXXXXXXXX$-0.12

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Lexicon Pharmaceuticals Valuation Multiples

Lexicon Pharmaceuticals trades at 12.8x EV/Revenue multiple, and (11.1x) EV/EBITDA.

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EV / Revenue (LTM)


Lexicon Pharmaceuticals Financial Valuation Multiples

As of March 21, 2026, Lexicon Pharmaceuticals has market cap of $650M and EV of $592M.

Equity research analysts estimate Lexicon Pharmaceuticals' 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX

Lexicon Pharmaceuticals has a P/E ratio of (11.8x).

LTMNTMLast FYFY 2026FY 2027FY 2028
Market cap (current)$650MXXX$650MXXXXXXXXX
EV (current)$592MXXX$592MXXXXXXXXX
EV/Revenue12.8xXXX11.9xXXXXXXXXX
EV/EBITDA(11.1x)XXX(14.3x)XXXXXXXXX
EV/EBIT(11.0x)XXX(12.1x)XXXXXXXXX
EV/Gross Profit12.9xXXX12.0xXXXXXXXXX
P/E(11.8x)XXX(12.9x)XXXXXXXXX
EV/FCF—XXX(8.7x)XXXXXXXXX

Valuation data powered by FactSet, Inc. and Morningstar, Inc.

Verified Lexicon Pharmaceuticals Valuation Multiples

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Lexicon Pharmaceuticals Margins & Growth Rates

Lexicon Pharmaceuticals' revenue in the last 12 month declined by (34%).

Lexicon Pharmaceuticals' revenue per employee in the last FY averaged $0.5M.

Lexicon Pharmaceuticals' rule of 40 is (149%) (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Lexicon Pharmaceuticals' rule of X is (199%) (created by Bessemer, rule of X is another metric to measure SaaS companies, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

See operational valuation multiples for Lexicon Pharmaceuticals and other 15K+ public comps

Lexicon Pharmaceuticals Operational Valuation Multiples

LTMNTMLast FYFY 2026FY 2027FY 2028
Revenue Growth(34%)XXX(32%)XXXXXXXXX
EBITDA Margin(115%)XXX(83%)XXXXXXXXX
EBITDA Growth45%XXX71%XXXXXXXXX
Rule of 40—XXX(149%)XXXXXXXXX
Bessemer Rule of X—XXX(199%)XXXXXXXXX
Revenue per Employee—XXX$0.5MXXXXXXXXX
G&A Expenses to Revenue81%XXX—XXXXXXXXX
R&D Expenses to Revenue134%XXX123%XXXXXXXXX
Opex to Revenue—XXX198%XXXXXXXXX

Valuation data powered by FactSet, Inc. and Morningstar, Inc.

Valuation Multiples Across 230+ Verticals

Lexicon Pharmaceuticals Public Comps

See public comps and valuation multiples for other Biopharmaceuticals comps.

EV/RevenueEV/EBITDA
LTM2026E2027ELTM2026E2027E
TTY BiopharmXXXXXXXXXXXXXXXXXX
uniQureXXXXXXXXXXXXXXXXXX
OcugenXXXXXXXXXXXXXXXXXX
Luzhu BiotechXXXXXXXXXXXXXXXXXX
Zura BioXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX

Valuation data powered by FactSet, Inc.

Lexicon Pharmaceuticals M&A Activity

Lexicon Pharmaceuticals acquired XXX companies to date.

Last acquisition by Lexicon Pharmaceuticals was on XXXXXXXX, XXXXX. Lexicon Pharmaceuticals acquired XXXXXXXX for XXX (EV/Revenue multiple of XXX).

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Latest Acquisitions by Lexicon Pharmaceuticals

Acquired CompanyValuationEV/RevenueEV/EBITDA
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX

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Lexicon Pharmaceuticals Investment Activity

Lexicon Pharmaceuticals invested in XXX companies to date.

Lexicon Pharmaceuticals made its latest investment on XXXXXXXX, XXXXX. Lexicon Pharmaceuticals invested in XXXXXXXX for XXX (EV/Revenue multiple of XXX).

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Latest Investments by Lexicon Pharmaceuticals

CompanyValuationEV/RevenueEV/EBITDA
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX

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About Lexicon Pharmaceuticals

When was Lexicon Pharmaceuticals founded?Lexicon Pharmaceuticals was founded in 1995.
Where is Lexicon Pharmaceuticals headquartered?Lexicon Pharmaceuticals is headquartered in United States.
How many employees does Lexicon Pharmaceuticals have?As of today, Lexicon Pharmaceuticals has over 103 employees.
Who is the CEO of Lexicon Pharmaceuticals?Lexicon Pharmaceuticals' CEO is Michael Exton.
Is Lexicon Pharmaceuticals publicly listed?Yes, Lexicon Pharmaceuticals is a public company listed on Nasdaq.
What is the stock symbol of Lexicon Pharmaceuticals?Lexicon Pharmaceuticals trades under LXRX ticker.
When did Lexicon Pharmaceuticals go public?Lexicon Pharmaceuticals went public in 2000.
Who are competitors of Lexicon Pharmaceuticals?Lexicon Pharmaceuticals main competitors are TTY Biopharm, uniQure, Ocugen, Luzhu Biotech.
What is the current market cap of Lexicon Pharmaceuticals?Lexicon Pharmaceuticals' current market cap is $650M.
What is the current revenue of Lexicon Pharmaceuticals?Lexicon Pharmaceuticals' last 12 months revenue is $46M.
What is the current revenue growth of Lexicon Pharmaceuticals?Lexicon Pharmaceuticals revenue growth (NTM/LTM) is (34%).
What is the current EV/Revenue multiple of Lexicon Pharmaceuticals?Current revenue multiple of Lexicon Pharmaceuticals is 12.8x.
Is Lexicon Pharmaceuticals profitable?No, Lexicon Pharmaceuticals is not profitable.
What is the current EBITDA of Lexicon Pharmaceuticals?Lexicon Pharmaceuticals has negative EBITDA and is not profitable.
What is Lexicon Pharmaceuticals' EBITDA margin?Lexicon Pharmaceuticals' last 12 months EBITDA margin is (115%).
What is the current EV/EBITDA multiple of Lexicon Pharmaceuticals?Current EBITDA multiple of Lexicon Pharmaceuticals is (11.1x).

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