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Lexicon Pharmaceuticals Valuation Multiples
Discover revenue and EBITDA valuation multiples for Lexicon Pharmaceuticals and similar public comparables like TTY Biopharm, uniQure, Ocugen, Luzhu Biotech and more.
Lexicon Pharmaceuticals Overview
About Lexicon Pharmaceuticals
Lexicon Pharmaceuticals Inc is a biopharmaceutical company. It is engaged in the discovery, development, and commercialization of pharmaceutical products for the treatment of human diseases. Some of its drug candidates are LX9211, an orally-delivered small molecule drug candidate, also developing LX9851, an orally-delivered small molecule drug candidate, as a treatment for obesity and associated cardiometabolic.
Founded
1995
HQ

Employees
103
Website
Sectors
Financials (LTM)
EV
$592M
Lexicon Pharmaceuticals Financials
Lexicon Pharmaceuticals reported last 12-month revenue of $46M and negative EBITDA of ($53M).
In the same LTM period, Lexicon Pharmaceuticals generated $46M in gross profit, ($53M) in EBITDA losses, and had net loss of ($55M).
Revenue (LTM)
Lexicon Pharmaceuticals P&L
In the most recent fiscal year, Lexicon Pharmaceuticals reported revenue of $50M and EBITDA of ($41M).
Lexicon Pharmaceuticals expects next 12-month revenue of XXX and NTM EBITDA of XXX
| LTM | NTM | Last FY | FY 2026 | FY 2027 | FY 2028 | |
|---|---|---|---|---|---|---|
| Revenue | $46M | XXX | $50M | XXX | XXX | XXX |
| Gross Profit | $46M | XXX | $50M | XXX | XXX | XXX |
| Gross Margin | 99% | XXX | 99% | XXX | XXX | XXX |
| EBITDA | ($53M) | XXX | ($41M) | XXX | XXX | XXX |
| EBITDA Margin | (115%) | XXX | (83%) | XXX | XXX | XXX |
| EBIT Margin | (116%) | XXX | (98%) | XXX | XXX | XXX |
| Net Profit | ($55M) | XXX | ($50M) | XXX | XXX | XXX |
| Net Margin | (119%) | XXX | (101%) | XXX | XXX | XXX |
| Net Debt | — | — | $20M | XXX | XXX | XXX |
Financial data powered by Morningstar, Inc.
Lexicon Pharmaceuticals Stock Performance
Lexicon Pharmaceuticals has current market cap of $650M, and enterprise value of $592M.
Market Cap Evolution
Lexicon Pharmaceuticals' stock price is $1.56.
| EV | Market Cap | Price 1D | Price 1M | Price 3M | Price 12M | EPS |
|---|---|---|---|---|---|---|
| $592M | $650M | 0.0% | XXX | XXX | XXX | $-0.12 |
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Start Free TrialLexicon Pharmaceuticals Valuation Multiples
Lexicon Pharmaceuticals trades at 12.8x EV/Revenue multiple, and (11.1x) EV/EBITDA.
EV / Revenue (LTM)
Lexicon Pharmaceuticals Financial Valuation Multiples
As of March 21, 2026, Lexicon Pharmaceuticals has market cap of $650M and EV of $592M.
Equity research analysts estimate Lexicon Pharmaceuticals' 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX
Lexicon Pharmaceuticals has a P/E ratio of (11.8x).
| LTM | NTM | Last FY | FY 2026 | FY 2027 | FY 2028 | |
|---|---|---|---|---|---|---|
| Market cap (current) | $650M | XXX | $650M | XXX | XXX | XXX |
| EV (current) | $592M | XXX | $592M | XXX | XXX | XXX |
| EV/Revenue | 12.8x | XXX | 11.9x | XXX | XXX | XXX |
| EV/EBITDA | (11.1x) | XXX | (14.3x) | XXX | XXX | XXX |
| EV/EBIT | (11.0x) | XXX | (12.1x) | XXX | XXX | XXX |
| EV/Gross Profit | 12.9x | XXX | 12.0x | XXX | XXX | XXX |
| P/E | (11.8x) | XXX | (12.9x) | XXX | XXX | XXX |
| EV/FCF | — | XXX | (8.7x) | XXX | XXX | XXX |
Valuation data powered by FactSet, Inc. and Morningstar, Inc.
Verified Lexicon Pharmaceuticals Valuation Multiples
Access all public comps and forward-looking valuation multiples like EV/Revenue in 2027, based on consensus analyst estimates. Powered by FactSet and Morningstar.


Lexicon Pharmaceuticals Margins & Growth Rates
Lexicon Pharmaceuticals' revenue in the last 12 month declined by (34%).
Lexicon Pharmaceuticals' revenue per employee in the last FY averaged $0.5M.
Lexicon Pharmaceuticals' rule of 40 is (149%) (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).
Lexicon Pharmaceuticals' rule of X is (199%) (created by Bessemer, rule of X is another metric to measure SaaS companies, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).
Lexicon Pharmaceuticals Operational Valuation Multiples
| LTM | NTM | Last FY | FY 2026 | FY 2027 | FY 2028 | |
|---|---|---|---|---|---|---|
| Revenue Growth | (34%) | XXX | (32%) | XXX | XXX | XXX |
| EBITDA Margin | (115%) | XXX | (83%) | XXX | XXX | XXX |
| EBITDA Growth | 45% | XXX | 71% | XXX | XXX | XXX |
| Rule of 40 | — | XXX | (149%) | XXX | XXX | XXX |
| Bessemer Rule of X | — | XXX | (199%) | XXX | XXX | XXX |
| Revenue per Employee | — | XXX | $0.5M | XXX | XXX | XXX |
| G&A Expenses to Revenue | 81% | XXX | — | XXX | XXX | XXX |
| R&D Expenses to Revenue | 134% | XXX | 123% | XXX | XXX | XXX |
| Opex to Revenue | — | XXX | 198% | XXX | XXX | XXX |
Valuation data powered by FactSet, Inc. and Morningstar, Inc.
Lexicon Pharmaceuticals Public Comps
See public comps and valuation multiples for other Biopharmaceuticals comps.
| EV/Revenue | EV/EBITDA | |||||
|---|---|---|---|---|---|---|
| LTM | 2026E | 2027E | LTM | 2026E | 2027E | |
| TTY Biopharm | XXX | XXX | XXX | XXX | XXX | XXX |
| uniQure | XXX | XXX | XXX | XXX | XXX | XXX |
| Ocugen | XXX | XXX | XXX | XXX | XXX | XXX |
| Luzhu Biotech | XXX | XXX | XXX | XXX | XXX | XXX |
| Zura Bio | XXX | XXX | XXX | XXX | XXX | XXX |
| XXXXXXXX | XXX | XXX | XXX | XXX | XXX | XXX |
| XXXXXXXX | XXX | XXX | XXX | XXX | XXX | XXX |
Valuation data powered by FactSet, Inc.
Lexicon Pharmaceuticals M&A Activity
Lexicon Pharmaceuticals acquired XXX companies to date.
Last acquisition by Lexicon Pharmaceuticals was on XXXXXXXX, XXXXX. Lexicon Pharmaceuticals acquired XXXXXXXX for XXX (EV/Revenue multiple of XXX).
Latest Acquisitions by Lexicon Pharmaceuticals
| Acquired Company | Valuation | EV/Revenue | EV/EBITDA |
|---|---|---|---|
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
Get Verified M&A Valuation Multiples
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Start Free TrialLexicon Pharmaceuticals Investment Activity
Lexicon Pharmaceuticals invested in XXX companies to date.
Lexicon Pharmaceuticals made its latest investment on XXXXXXXX, XXXXX. Lexicon Pharmaceuticals invested in XXXXXXXX for XXX (EV/Revenue multiple of XXX).
Latest Investments by Lexicon Pharmaceuticals
| Company | Valuation | EV/Revenue | EV/EBITDA |
|---|---|---|---|
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
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Start Free TrialAbout Lexicon Pharmaceuticals
| When was Lexicon Pharmaceuticals founded? | Lexicon Pharmaceuticals was founded in 1995. |
| Where is Lexicon Pharmaceuticals headquartered? | Lexicon Pharmaceuticals is headquartered in United States. |
| How many employees does Lexicon Pharmaceuticals have? | As of today, Lexicon Pharmaceuticals has over 103 employees. |
| Who is the CEO of Lexicon Pharmaceuticals? | Lexicon Pharmaceuticals' CEO is Michael Exton. |
| Is Lexicon Pharmaceuticals publicly listed? | Yes, Lexicon Pharmaceuticals is a public company listed on Nasdaq. |
| What is the stock symbol of Lexicon Pharmaceuticals? | Lexicon Pharmaceuticals trades under LXRX ticker. |
| When did Lexicon Pharmaceuticals go public? | Lexicon Pharmaceuticals went public in 2000. |
| Who are competitors of Lexicon Pharmaceuticals? | Lexicon Pharmaceuticals main competitors are TTY Biopharm, uniQure, Ocugen, Luzhu Biotech. |
| What is the current market cap of Lexicon Pharmaceuticals? | Lexicon Pharmaceuticals' current market cap is $650M. |
| What is the current revenue of Lexicon Pharmaceuticals? | Lexicon Pharmaceuticals' last 12 months revenue is $46M. |
| What is the current revenue growth of Lexicon Pharmaceuticals? | Lexicon Pharmaceuticals revenue growth (NTM/LTM) is (34%). |
| What is the current EV/Revenue multiple of Lexicon Pharmaceuticals? | Current revenue multiple of Lexicon Pharmaceuticals is 12.8x. |
| Is Lexicon Pharmaceuticals profitable? | No, Lexicon Pharmaceuticals is not profitable. |
| What is the current EBITDA of Lexicon Pharmaceuticals? | Lexicon Pharmaceuticals has negative EBITDA and is not profitable. |
| What is Lexicon Pharmaceuticals' EBITDA margin? | Lexicon Pharmaceuticals' last 12 months EBITDA margin is (115%). |
| What is the current EV/EBITDA multiple of Lexicon Pharmaceuticals? | Current EBITDA multiple of Lexicon Pharmaceuticals is (11.1x). |
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