- Companies
- Heartseed
Heartseed Valuation Multiples
Heartseed is valued at $387M as of October 2026, a 54.3x revenue multiple. In the last 12 months, Heartseed revenue was $6M.
Heartseed Overview
About Heartseed
Heartseed Inc is a Japanese biotechnology company focused on developing and commercializing regenerative medicine treatments for severe heart failure. The company's product candidate, HS-001, involves transplanting clusters of purified heart muscle cells derived from iPSCs to the patient's heart to treat heart failure, especially Heart Failure with reduced Left Ventricular Ejection Fraction (HFrEF), including conditions such as Dilated Cardiomyopathy, Old Myocardial Infarction, and Dilated phase of Hypertrophic Cardiomyopathy.
Founded
2015
HQ
Employees
45
Website
Sectors
Financials (LTM)
EV
$347M
Valuation Multiples
Start free trialHeartseed Financials
Heartseed reported last 12-month revenue of $6M.
In the same LTM period, Heartseed generated had net loss of ($8M).
Revenue (LTM)
Heartseed P&L
In the most recent fiscal year, Heartseed reported revenue of $19M and EBITDA of $2M.
Heartseed is profitable as of last fiscal year, with gross margin of 100%, EBITDA margin of 11%, and net margin of 6%.
Financial data powered by Morningstar, Inc.
Heartseed Stock Performance
Heartseed has current market cap of $387M, and enterprise value of $347M.
Market Cap Evolution
Heartseed's stock price is $16.89.
Heartseed share price increased by 1.6% in the last 30 days, and by 50.3% in the last year.
Heartseed has an EPS (earnings per share) of $0.05.
| EV | Market Cap | Price 1D | Price 1M | Price 3M | Price 12M | EPS |
|---|---|---|---|---|---|---|
| $347M | $387M | -2.3% | 1.6% | 58.8% | 50.3% | $0.05 |
Benchmark Trading Valuation Multiples by Industry
Sign up to access valuation multiples like growth-adjusted P/E, Rule of 40, next 12-month EV/Revenue, EBITDA multiples by industry, consensus analyst estimates and many more.
Start Free TrialHeartseed Valuation Multiples
Heartseed trades at 54.3x EV/Revenue multiple, and 163.1x EV/EBITDA.
EV / Revenue (LTM)
Heartseed Financial Valuation Multiples
As of October 16, 2026, Heartseed has market cap of $387M and EV of $347M.
Heartseed has a P/E ratio of (47.2x).
Multiples above and below 250x are considered non-meaningful (n/m). Valuation data powered by FactSet, Inc. and Morningstar, Inc.
Verified Heartseed Valuation Multiples
Access all public comps and forward-looking valuation multiples like EV/Revenue in 2027, based on consensus analyst estimates. Powered by FactSet and Morningstar.


Heartseed Margins & Growth Rates
Heartseed decreased revenue by 85% and net profit by 1042% in the last fiscal year.
In the most recent fiscal year, Heartseed reported gross margin of 100%, EBITDA margin of 11%, and net margin of 6%.
Heartseed Margins
Heartseed Growth Rates
Data powered by FactSet, Inc. and Morningstar, Inc.
Heartseed Operational KPIs
Heartseed's revenue per employee in the last FY averaged $0.4M, while opex per employee averaged $0.4M for the same period.
Data powered by FactSet, Inc. and Morningstar, Inc.
Heartseed Competitors
Heartseed competitors include Luzhu Biotech, Scribe Therapeutics, Lumosa Therapeutics, Rezolute, Swedencare, Indaptus Therapeutics, Allergy Therapuetics, Galectin Therapeutics, Editas Medicine and Formycon.
Most Heartseed public comparables operate across Biopharmaceuticals and BioTech.
| Last FY | EV/Revenue | EV/EBITDA | ||||||
|---|---|---|---|---|---|---|---|---|
| Revenue | EBITDA | Last FY | LTM | 2027E | Last FY | LTM | 2027E | |
| - | ($17M) | - | 878.9x | (22.5x) | (23.3x) | |||
| $51M | ($21M) | 10.0x | - | (23.9x) | - | |||
| $1M | ($11M) | 336.0x | 326.0x | (34.3x) | - | |||
| - | ($83M) | - | 356.9x | (3.3x) | - | |||
| $269M | $45M | 2.0x | 1.9x | 12.1x | 9.5x | |||
| - | ($21M) | - | - | (17.5x) | - | |||
| $73M | ($38M) | 5.8x | 5.3x | (11.1x) | (9.2x) | |||
| - | ($24M) | - | - | (21.2x) | (27.8x) | |||
This data is available for Pro users. Sign up to see all Heartseed competitors and their valuation data. Start Free Trial | ||||||||
Heartseed VC Funding History
Before going public, Heartseed raised $87M in total equity funding, across 6 rounds.
Heartseed Funding Rounds
Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples
Sign up to see data on 350K+ funding rounds and disclosed revenue and EBITDA valuation multiples, from seed, through growth stage, to pre-IPO.
Start Free TrialAbout Heartseed
| When was Heartseed founded? | Heartseed was founded in 2015. |
| Where is Heartseed headquartered? | Heartseed is headquartered in Japan. |
| How many employees does Heartseed have? | As of today, Heartseed has over 45 employees. |
| Who is the CEO of Heartseed? | Heartseed's CEO is Keiichi Fukuda. |
| Is Heartseed publicly listed? | Yes, Heartseed is a public company listed on Tokyo Stock Exchange. |
| What is the stock symbol of Heartseed? | Heartseed trades under 219A ticker. |
| When did Heartseed go public? | Heartseed went public in 2024. |
| Who are competitors of Heartseed? | Heartseed main competitors include Luzhu Biotech, Scribe Therapeutics, Lumosa Therapeutics, Rezolute, Swedencare, Indaptus Therapeutics, Allergy Therapuetics, Galectin Therapeutics, Editas Medicine, Formycon. |
| What is the current market cap of Heartseed? | Heartseed's current market cap is $387M. |
| What is the current revenue of Heartseed? | Heartseed's last 12 months revenue is $6M. |
| What is the current revenue growth of Heartseed? | Heartseed revenue growth (NTM/LTM) is (89%). |
| What is the current EV/Revenue multiple of Heartseed? | Current revenue multiple of Heartseed is 54.3x. |
| Is Heartseed profitable? | No, Heartseed is not profitable. |
| What is the current net income of Heartseed? | Heartseed's last 12 months net income is ($8M). |
| How many companies Heartseed has acquired to date? | Heartseed hasn't acquired any companies yet (or none have been disclosed publicly). |
| In how many companies Heartseed has invested to date? | Heartseed hasn't invested in any companies yet (or none have been disclosed publicly). |
See public comps similar to Heartseed
Lists including Heartseed
Start Your
Free Trial Today
Try Multiples for free for 3 days. Got questions or need a demo? Schedule a call with us below.




