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Mesoblast Valuation Multiples

Discover revenue and EBITDA valuation multiples for Mesoblast and similar public comparables like Zymeworks, Agios Pharmaceuticals, Jafron Biomedical, Zhejiang Wolwo Bio-Pharma and more.

Mesoblast Overview

About Mesoblast

Mesoblast Ltd is a commercial-stage biotechnology company and a world leader in developing allogeneic (off-the-shelf) cellular medicines for the treatment of severe and life-threatening inflammatory conditions. The company's product candidates include: Ryoncil (remestemcel-L) for the treatment of steroid-refractory acute graft versus host disease, as well as for the treatment of moderate to severe acute respiratory distress syndrome; Revascor (rexlemestrocel-L) for the treatment of chronic heart failure; and Rexlemestrocel-L for chronic low back pain. The company is managed as one operating segment, being the development of an adult stem cell technology platform for commercialization.


Founded

2004

HQ

Australia

Employees

81

Financials (LTM)

Revenue: $104M
EBITDA: ($32M)

EV

$2B

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Mesoblast Financials

Mesoblast reported last 12-month revenue of $104M and negative EBITDA of ($32M).

In the same LTM period, Mesoblast generated $90M in gross profit, ($32M) in EBITDA losses, and had net loss of ($60M).

Revenue (LTM)


Mesoblast P&L

In the most recent fiscal year, Mesoblast reported revenue of $17M and EBITDA of ($69M).

Mesoblast expects next 12-month revenue of XXX and NTM EBITDA of XXX

See Mesoblast forward-looking valuation multiples
LTMNTMLast FYFY 2026FY 2027FY 2028
Revenue$104MXXX$17MXXXXXXXXX
Gross Profit$90MXXX$12MXXXXXXXXX
Gross Margin87%XXX70%XXXXXXXXX
EBITDA($32M)XXX($69M)XXXXXXXXX
EBITDA Margin(30%)XXX(399%)XXXXXXXXX
EBIT Margin(42%)XXX(363%)XXXXXXXXX
Net Profit($60M)XXX($102M)XXXXXXXXX
Net Margin(58%)XXX(594%)XXXXXXXXX

Financial data powered by Morningstar, Inc.

Mesoblast Stock Performance

Mesoblast has current market cap of $2B, and enterprise value of $2B.

Market Cap Evolution


Mesoblast's stock price is $1.61.

See Mesoblast trading valuation data
EVMarket CapPrice 1DPrice 1MPrice 3MPrice 12MEPS
$2B$2B0.2%XXXXXXXXX$-0.08

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Mesoblast Valuation Multiples

Mesoblast trades at 20.0x EV/Revenue multiple, and (66.0x) EV/EBITDA.

See valuation multiples for Mesoblast and 15K+ public comps

EV / Revenue (LTM)


Mesoblast Financial Valuation Multiples

As of April 18, 2026, Mesoblast has market cap of $2B and EV of $2B.

Equity research analysts estimate Mesoblast's 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX

Mesoblast has a P/E ratio of (34.4x).

LTMNTMLast FYFY 2026FY 2027FY 2028
Market cap (current)$2BXXX$2BXXXXXXXXX
EV (current)$2BXXX$2BXXXXXXXXX
EV/Revenue20.0xXXX121.0xXXXXXXXXX
EV/EBITDA(66.0x)XXX(30.3x)XXXXXXXXX
EV/EBIT(48.0x)XXX(33.3x)XXXXXXXXX
EV/Gross Profit23.0xXXX172.4xXXXXXXXXX
P/E(34.4x)XXX(20.3x)XXXXXXXXX
EV/FCF(43.3x)XXX(41.1x)XXXXXXXXX

Valuation data powered by FactSet, Inc. and Morningstar, Inc.

Verified Mesoblast Valuation Multiples

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Mesoblast Margins & Growth Rates

Mesoblast's revenue in the last 12 month grew by 95%.

Mesoblast's revenue per employee in the last FY averaged $0.2M, while opex per employee averaged $0.9M for the same period.

Mesoblast's rule of 40 is 153% (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Mesoblast's rule of X is 369% (created by Bessemer, rule of X is another metric to measure SaaS companies, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

See operational valuation multiples for Mesoblast and other 15K+ public comps

Mesoblast Operational Valuation Multiples

LTMNTMLast FYFY 2026FY 2027FY 2028
Revenue Growth95%XXX631%XXXXXXXXX
EBITDA Margin(30%)XXX(399%)XXXXXXXXX
EBITDA Growth(229%)XXX(68%)XXXXXXXXX
Rule of 40—XXX153%XXXXXXXXX
Bessemer Rule of X—XXX369%XXXXXXXXX
Revenue per Employee—XXX$0.2MXXXXXXXXX
Opex per Employee—XXX$0.9MXXXXXXXXX
S&M Expenses to Revenue—XXX94%XXXXXXXXX
G&A Expenses to Revenue42%XXX229%XXXXXXXXX
R&D Expenses to Revenue72%XXX202%XXXXXXXXX
Opex to Revenue—XXX433%XXXXXXXXX

Valuation data powered by FactSet, Inc. and Morningstar, Inc.

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Mesoblast Public Comps

See public comps and valuation multiples for other Biopharmaceuticals comps.

EV/RevenueEV/EBITDA
LTM2026E2027ELTM2026E2027E
MesoblastXXXXXXXXXXXXXXXXXX
ZymeworksXXXXXXXXXXXXXXXXXX
Agios PharmaceuticalsXXXXXXXXXXXXXXXXXX
Jafron BiomedicalXXXXXXXXXXXXXXXXXX
Zhejiang Wolwo Bio-PharmaXXXXXXXXXXXXXXXXXX
Neuland LaboratoriesXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX

Valuation data powered by FactSet, Inc.

Mesoblast M&A Activity

Mesoblast acquired XXX companies to date.

Last acquisition by Mesoblast was on XXXXXXXX, XXXXX. Mesoblast acquired XXXXXXXX for XXX (EV/Revenue multiple of XXX).

See M&A valuation multiples

Latest Acquisitions by Mesoblast

Acquired CompanyValuationEV/RevenueEV/EBITDA
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX

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Mesoblast Investment Activity

Mesoblast invested in XXX companies to date.

Mesoblast made its latest investment on XXXXXXXX, XXXXX. Mesoblast invested in XXXXXXXX for XXX (EV/Revenue multiple of XXX).

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Latest Investments by Mesoblast

CompanyValuationEV/RevenueEV/EBITDA
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX

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About Mesoblast

When was Mesoblast founded?Mesoblast was founded in 2004.
Where is Mesoblast headquartered?Mesoblast is headquartered in Australia.
How many employees does Mesoblast have?As of today, Mesoblast has over 81 employees.
Who is the CEO of Mesoblast?Mesoblast's CEO is Silviu Itescu.
Is Mesoblast publicly listed?Yes, Mesoblast is a public company listed on Australian Securities Exchange.
What is the stock symbol of Mesoblast?Mesoblast trades under MSB ticker.
When did Mesoblast go public?Mesoblast went public in 2004.
Who are competitors of Mesoblast?Mesoblast main competitors are Zymeworks, Agios Pharmaceuticals, Jafron Biomedical, Zhejiang Wolwo Bio-Pharma.
What is the current market cap of Mesoblast?Mesoblast's current market cap is $2B.
What is the current revenue of Mesoblast?Mesoblast's last 12 months revenue is $104M.
What is the current revenue growth of Mesoblast?Mesoblast revenue growth (NTM/LTM) is 95%.
What is the current EV/Revenue multiple of Mesoblast?Current revenue multiple of Mesoblast is 20.0x.
Is Mesoblast profitable?No, Mesoblast is not profitable.
What is the current EBITDA of Mesoblast?Mesoblast has negative EBITDA and is not profitable.
What is Mesoblast's EBITDA margin?Mesoblast's last 12 months EBITDA margin is (30%).
What is the current EV/EBITDA multiple of Mesoblast?Current EBITDA multiple of Mesoblast is (66.0x).
What is the current FCF of Mesoblast?Mesoblast's last 12 months FCF is ($48M).
What is Mesoblast's FCF margin?Mesoblast's last 12 months FCF margin is (46%).
What is the current EV/FCF multiple of Mesoblast?Current FCF multiple of Mesoblast is (43.3x).

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