GeneDx Holdings Corp delivers personalized and actionable health insights to inform diagnosis, direct treatment and improve drug discovery. The company is uniquely positioned to accelerate the use of genomic and large-scale clinical information to enable precision medicine as the standard of care. The company is at the forefront of transforming healthcare through its various exome and genome testing and interpretation, fueled by one of the world’s substantial rare disease data sets.
2020
1K+
LTM Revenue $418M
LTM EBITDA $37.9M
$4.6B
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As of November 2025, GeneDx reported last 12-month revenue of $418M and EBITDA of $37.9M.
In the same period, GeneDx generated $292M in LTM gross profit and $37.2M in net income.
See GeneDx valuation multiples based on analyst estimatesIn the most recent fiscal year, GeneDx reported revenue of $305M and EBITDA of -$1.3M.
GeneDx expects next 12-month revenue of XXX   and NTM EBITDA of XXX
See GeneDx valuation multiples based on analyst estimates| LTM | NTM | Last FY | FY 2025 | FY 2026 | FY 2027 | |
|---|---|---|---|---|---|---|
| Revenue | $418M | XXX | $305M | XXX | XXX | XXX |
| Gross Profit | $292M | XXX | $194M | XXX | XXX | XXX |
| Gross Margin | 70% | XXX | 64% | XXX | XXX | XXX |
| EBITDA | $37.9M | XXX | -$1.3M | XXX | XXX | XXX |
| EBITDA Margin | 9% | XXX | 0% | XXX | XXX | XXX |
| EBIT | $35.7M | XXX | -$23.2M | XXX | XXX | XXX |
| EBIT Margin | 9% | XXX | -8% | XXX | XXX | XXX |
| Net Profit | $37.2M | XXX | -$52.3M | XXX | XXX | XXX |
| Net Margin | 9% | XXX | -17% | XXX | XXX | XXX |
| Net Debt | XXX | XXX | n/a | XXX | XXX | XXX |
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GeneDx has current market cap of $4.6B, and EV of $4.6B.
As of December 4, 2025, GeneDx's stock price is $160.
See GeneDx trading valuation data| EV | Market Cap | Price 1D | Price 1M | Price 3M | Price 12M | EPS |
|---|---|---|---|---|---|---|
| $4.6B | $4.6B | XXX | XXX | XXX | XXX | $1.27 |
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Start Free TrialGeneDx's trades at 15.0x EV/Revenue multiple, and -3645.8x EV/EBITDA.
See valuation multiples for GeneDx and 15K+ public compsAs of December 4, 2025, GeneDx has market cap of $4.6B and EV of $4.6B.
Equity research analysts estimate GeneDx's 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX
GeneDx has a P/E ratio of 124.5x.
| LTM | NTM | Last FY | FY 2025 | FY 2026 | FY 2027 | |
|---|---|---|---|---|---|---|
| Market cap (current) | $4.6B | XXX | $4.6B | XXX | XXX | XXX |
| EV (current) | $4.6B | XXX | $4.6B | XXX | XXX | XXX |
| EV/Revenue | 11.0x | XXX | 15.0x | XXX | XXX | XXX |
| EV/EBITDA | 121.3x | XXX | -3645.8x | XXX | XXX | XXX |
| EV/EBIT | 128.8x | XXX | -197.9x | XXX | XXX | XXX |
| EV/Gross Profit | 15.7x | XXX | n/a | XXX | XXX | XXX |
| P/E | 124.5x | XXX | -88.7x | XXX | XXX | XXX |
| EV/FCF | n/a | XXX | -135.2x | XXX | XXX | XXX |
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Start Free TrialGeneDx's last 12 month revenue growth is 24%
GeneDx's revenue per employee in the last FY averaged $0.3M, while opex per employee averaged $0.2M for the same period.
GeneDx's rule of 40 is -43% (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).
GeneDx's rule of X is 70% (created by Bessemer, rule of X is another metric relevant for SaaS companies only, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).
See operational valuation multiples for GeneDx and other 15K+ public comps| LTM | NTM | Last FY | FY 2025 | FY 2026 | FY 2027 | |
|---|---|---|---|---|---|---|
| Revenue Growth | 24% | XXX | 31% | XXX | XXX | XXX |
| EBITDA Margin | 9% | XXX | 0% | XXX | XXX | XXX |
| EBITDA Growth | -51% | XXX | n/a | XXX | XXX | XXX |
| Rule of 40 | -43% | XXX | 24% | XXX | XXX | XXX |
| Bessemer Rule of X | XXX | XXX | 70% | XXX | XXX | XXX |
| Revenue per Employee | XXX | XXX | $0.3M | XXX | XXX | XXX |
| Opex per Employee | XXX | XXX | $0.2M | XXX | XXX | XXX |
| S&M Expenses to Revenue | XXX | XXX | 22% | XXX | XXX | XXX |
| G&A Expenses to Revenue | XXX | XXX | n/a | XXX | XXX | XXX |
| R&D Expenses to Revenue | XXX | XXX | 15% | XXX | XXX | XXX |
| Opex to Revenue | XXX | XXX | 71% | XXX | XXX | XXX |
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| EV/Revenue | EV/EBITDA | |||||
|---|---|---|---|---|---|---|
| 2025E | 2026E | 2027E | 2025E | 2026E | 2027E | |
| EZZ Life Science | XXX | XXX | XXX | XXX | XXX | XXX |
| Epigenomics | XXX | XXX | XXX | XXX | XXX | XXX |
| Mirxes Holding Co | XXX | XXX | XXX | XXX | XXX | XXX |
| ToolGen | XXX | XXX | XXX | XXX | XXX | XXX |
| 4basebio | XXX | XXX | XXX | XXX | XXX | XXX |
| XXXXXXXX | XXX | XXX | XXX | XXX | XXX | XXX |
| XXXXXXXX | XXX | XXX | XXX | XXX | XXX | XXX |
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GeneDx acquired XXX companies to date.
Last acquisition by GeneDx was XXXXXXXX, XXXXX XXXXX XXXXXX . GeneDx acquired XXXXXXXX for XXX (EV/Revenue multiple of XXX ).
See M&A valuation multiples| Acquired Company | EV | EV/Revenue | EV/EBITDA |
|---|---|---|---|
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
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Start Free Trial| When was GeneDx founded? | GeneDx was founded in 2020. |
| Where is GeneDx headquartered? | GeneDx is headquartered in United States of America. |
| How many employees does GeneDx have? | As of today, GeneDx has 1K+ employees. |
| Who is the CEO of GeneDx? | GeneDx's CEO is Ms. Katherine A. Stueland. |
| Is GeneDx publicy listed? | Yes, GeneDx is a public company listed on NAS. |
| What is the stock symbol of GeneDx? | GeneDx trades under WGS ticker. |
| When did GeneDx go public? | GeneDx went public in 2021. |
| Who are competitors of GeneDx? | Similar companies to GeneDx include e.g. EZZ Life Science, Epigenomics, Mirxes Holding Co, ToolGen. |
| What is the current market cap of GeneDx? | GeneDx's current market cap is $4.6B |
| What is the current revenue of GeneDx? | GeneDx's last 12 months revenue is $418M. |
| What is the current revenue growth of GeneDx? | GeneDx revenue growth (NTM/LTM) is 24%. |
| What is the current EV/Revenue multiple of GeneDx? | Current revenue multiple of GeneDx is 11.0x. |
| Is GeneDx profitable? | Yes, GeneDx is EBITDA-positive (as of the last 12 months). |
| What is the current EBITDA of GeneDx? | GeneDx's last 12 months EBITDA is $37.9M. |
| What is GeneDx's EBITDA margin? | GeneDx's last 12 months EBITDA margin is 9%. |
| What is the current EV/EBITDA multiple of GeneDx? | Current EBITDA multiple of GeneDx is 121.3x. |
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