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Exact Sciences Valuation Multiples

Discover revenue and EBITDA valuation multiples for Exact Sciences and similar public comparables like Healius, Cyclopharm, and CurveBeam AI.

Exact Sciences Overview

About Exact Sciences

Exact Sciences, headquartered in Madison, Wisconsin, provides cancer screening and diagnostic test products in the United States and internationally. Exact’s Cologuard screening test is a noninvasive stool-based DNA test for colorectal cancer. The company also competes in the precision oncology market with Oncotype DX, a suite of tissue-based genomic tests for estimating recurrence risk and likelihood of benefit from chemotherapy for breast and colon cancer, and OncoExTra, a liquid-based comprehensive genomic profiling test. It is also developing liquid biopsy tests for molecular residual disease, colorectal cancer screening, and multicancer screening.


Founded

1995

HQ

United States of America
Employees

7K+

Financials

LTM Revenue $2.9B

LTM EBITDA $371M

EV

$12.4B

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Exact Sciences Financials

Exact Sciences has a last 12-month revenue (LTM) of $2.9B and a last 12-month EBITDA of $371M.

In the most recent fiscal year, Exact Sciences achieved revenue of $2.8B and an EBITDA of -$789M.

Exact Sciences expects next 12-month revenue of  XXX    and NTM EBITDA of  XXX

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Exact Sciences P&L

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue $2.9B XXX $2.8B XXX XXX XXX
Gross Profit $2.1B XXX $1.9B XXX XXX XXX
Gross Margin 72% XXX 70% XXX XXX XXX
EBITDA $371M XXX -$789M XXX XXX XXX
EBITDA Margin 13% XXX -29% XXX XXX XXX
EBIT -$620M XXX -$179M XXX XXX XXX
EBIT Margin -21% XXX -6% XXX XXX XXX
Net Profit -$657M XXX -$1.0B XXX XXX XXX
Net Margin -23% XXX -37% XXX XXX XXX
Net Debt XXX XXX $2.0B XXX XXX XXX

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Exact Sciences Stock Performance

As of May 30, 2025, Exact Sciences's stock price is $56.

Exact Sciences has current market cap of $10.6B, and EV of $12.4B.

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Exact Sciences Stock Data

EV Market Cap Price 1D Price 1M Price 3M Price 12M EPS
$12.4B $10.6B XXX XXX XXX XXX $-3.46

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Exact Sciences Valuation Multiples

As of May 30, 2025, Exact Sciences has market cap of $10.6B and EV of $12.4B.

Exact Sciences's trades at 4.5x EV/Revenue multiple, and -15.6x EV/EBITDA.

Equity research analysts estimate Exact Sciences's 2025E EV/Revenue multiple at  XXX and 2025E EV/EBITDA multiple at  XXX

Exact Sciences has a P/E ratio of -16.2x.

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Exact Sciences Financial Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Market cap (current) $10.6B XXX $10.6B XXX XXX XXX
EV (current) $12.4B XXX $12.4B XXX XXX XXX
EV/Revenue 4.3x XXX 4.5x XXX XXX XXX
EV/EBITDA 33.3x XXX -15.6x XXX XXX XXX
EV/EBIT -19.9x XXX -68.9x XXX XXX XXX
EV/Gross Profit 5.9x XXX n/a XXX XXX XXX
P/E -16.2x XXX -10.3x XXX XXX XXX
EV/FCF 88.2x XXX 165.7x XXX XXX XXX

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Exact Sciences Margins & Growth Rates

Exact Sciences's last 12 month revenue growth is 13%

Exact Sciences's revenue per employee in the last FY averaged $0.4M, while opex per employee averaged $0.3M for the same period.

Exact Sciences's rule of 40 is 14% (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Exact Sciences's rule of X is 44% (created by Bessemer, rule of X is another metric relevant for SaaS companies only, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

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Exact Sciences Operational Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue Growth 13% XXX 13% XXX XXX XXX
EBITDA Margin 13% XXX -29% XXX XXX XXX
EBITDA Growth 37% XXX 287% XXX XXX XXX
Rule of 40 14% XXX -16% XXX XXX XXX
Bessemer Rule of X XXX XXX 44% XXX XXX XXX
Revenue per Employee XXX XXX $0.4M XXX XXX XXX
Opex per Employee XXX XXX $0.3M XXX XXX XXX
S&M Expenses to Revenue XXX XXX 9% XXX XXX XXX
G&A Expenses to Revenue XXX XXX n/a XXX XXX XXX
R&D Expenses to Revenue XXX XXX 16% XXX XXX XXX
Opex to Revenue XXX XXX 76% XXX XXX XXX

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Exact Sciences Public Comps

See public comps and valuation multiples for Medical Imaging & Diagnostics and Genomics & Personalized Medicine comps
EV/Revenue EV/EBITDA
2025E 2026E 2027E 2025E 2026E 2027E
Australian Clinical Labs XXX XXX XXX XXX XXX XXX
Clarity Pharmaceuticals XXX XXX XXX XXX XXX XXX
CurveBeam AI XXX XXX XXX XXX XXX XXX
Cyclopharm XXX XXX XXX XXX XXX XXX
Healius XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX

Valuation data powered by FactSet, Inc.

Exact Sciences M&A and Investment Activity

Exact Sciences acquired  XXX companies to date.

Last acquisition by Exact Sciences was  XXXXXXXX, XXXXX XXXXX XXXXXX . Exact Sciences acquired  XXXXXXXX for  XXX (EV/Revenue multiple of  XXX ).

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Latest Acquisitions by Exact Sciences

Acquired Company EV EV/Revenue EV/EBITDA
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX

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About Exact Sciences

When was Exact Sciences founded? Exact Sciences was founded in 1995.
Where is Exact Sciences headquartered? Exact Sciences is headquartered in United States of America.
How many employees does Exact Sciences have? As of today, Exact Sciences has 7K+ employees.
Who is the CEO of Exact Sciences? Exact Sciences's CEO is Mr. Kevin T. Conroy.
Is Exact Sciences publicy listed? Yes, Exact Sciences is a public company listed on NAS.
What is the stock symbol of Exact Sciences? Exact Sciences trades under EXAS ticker.
When did Exact Sciences go public? Exact Sciences went public in 2001.
Who are competitors of Exact Sciences? Similar companies to Exact Sciences include e.g. Australian Clinical Labs, Clarity Pharmaceuticals, CurveBeam AI, Cyclopharm.
What is the current market cap of Exact Sciences? Exact Sciences's current market cap is $10.6B
What is the current revenue of Exact Sciences? Exact Sciences's last 12 months revenue is $2.9B.
What is the current revenue growth of Exact Sciences? Exact Sciences revenue growth (NTM/LTM) is 13%.
What is the current EV/Revenue multiple of Exact Sciences? Current revenue multiple of Exact Sciences is 4.3x.
Is Exact Sciences profitable? Yes, Exact Sciences is EBITDA-positive (as of the last 12 months).
What is the current EBITDA of Exact Sciences? Exact Sciences's last 12 months EBITDA is $371M.
What is Exact Sciences's EBITDA margin? Exact Sciences's last 12 months EBITDA margin is 13%.
What is the current EV/EBITDA multiple of Exact Sciences? Current EBITDA multiple of Exact Sciences is 33.3x.
What is the current FCF of Exact Sciences? Exact Sciences's last 12 months FCF is $140M.
What is Exact Sciences's FCF margin? Exact Sciences's last 12 months FCF margin is 5%.
What is the current EV/FCF multiple of Exact Sciences? Current FCF multiple of Exact Sciences is 88.2x.

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