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C4 Therapeutics Valuation Multiples

Discover revenue and EBITDA valuation multiples for C4 Therapeutics and similar public comparables like Vivoryon Therapeutics, Pharming, and Galapagos.

C4 Therapeutics Overview

About C4 Therapeutics

C4 Therapeutics Inc is a clinical-stage biopharmaceutical company dedicated to delivering on the promise of targeted protein degradation science to create a new generation of medicines that transforms patients’ lives. The Company is progressing targeted oncology programs through clinical studies and leveraging its TORPEDO platform to efficiently design and optimize small-molecule medicines to address difficult-to-treat diseases. Its degrader medicines are designed to harness the body’s natural protein recycling system to rapidly degrade disease-causing proteins, offering the potential to overcome drug resistance, and drug undruggable targets and improve patient outcomes. Its pipeline is Cemsidomide, CFT1946, and CFT8919.


Founded

2015

HQ

United States of America
Employees

110

Financials

LTM Revenue $30.3M

LTM EBITDA -$110M

EV

-$62.0M

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C4 Therapeutics Financials

C4 Therapeutics has a last 12-month revenue (LTM) of $30.3M and a last 12-month EBITDA of -$110M.

In the most recent fiscal year, C4 Therapeutics achieved revenue of $35.6M and an EBITDA of -$103M.

C4 Therapeutics expects next 12-month revenue of  XXX    and NTM EBITDA of  XXX

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C4 Therapeutics P&L

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue $30.3M XXX $35.6M XXX XXX XXX
Gross Profit $30.3M XXX n/a XXX XXX XXX
Gross Margin 100% XXX n/a XXX XXX XXX
EBITDA -$110M XXX -$103M XXX XXX XXX
EBITDA Margin -365% XXX -290% XXX XXX XXX
EBIT -$120M XXX -$117M XXX XXX XXX
EBIT Margin -395% XXX -329% XXX XXX XXX
Net Profit -$113M XXX -$105M XXX XXX XXX
Net Margin -372% XXX -296% XXX XXX XXX
Net Debt XXX XXX n/a XXX XXX XXX

Financial data powered by Morningstar, Inc.

C4 Therapeutics Stock Performance

As of May 30, 2025, C4 Therapeutics's stock price is $1.

C4 Therapeutics has current market cap of $88.8M, and EV of -$62.0M.

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C4 Therapeutics Stock Data

EV Market Cap Price 1D Price 1M Price 3M Price 12M EPS
-$62.0M $88.8M XXX XXX XXX XXX $-1.59

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C4 Therapeutics Valuation Multiples

As of May 30, 2025, C4 Therapeutics has market cap of $88.8M and EV of -$62.0M.

C4 Therapeutics's trades at -1.7x EV/Revenue multiple, and 0.6x EV/EBITDA.

Equity research analysts estimate C4 Therapeutics's 2025E EV/Revenue multiple at  XXX and 2025E EV/EBITDA multiple at  XXX

C4 Therapeutics has a P/E ratio of -0.8x.

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C4 Therapeutics Financial Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Market cap (current) $88.8M XXX $88.8M XXX XXX XXX
EV (current) -$62.0M XXX -$62.0M XXX XXX XXX
EV/Revenue -2.0x XXX -1.7x XXX XXX XXX
EV/EBITDA 0.6x XXX 0.6x XXX XXX XXX
EV/EBIT 0.5x XXX 0.5x XXX XXX XXX
EV/Gross Profit -2.0x XXX n/a XXX XXX XXX
P/E -0.8x XXX -0.8x XXX XXX XXX
EV/FCF 0.6x XXX 0.9x XXX XXX XXX

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C4 Therapeutics Margins & Growth Rates

C4 Therapeutics's last 12 month revenue growth is -26%

C4 Therapeutics's revenue per employee in the last FY averaged $0.3M, while opex per employee averaged $1.4M for the same period.

C4 Therapeutics's rule of 40 is -643% (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

C4 Therapeutics's rule of X is -431% (created by Bessemer, rule of X is another metric relevant for SaaS companies only, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

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C4 Therapeutics Operational Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue Growth -26% XXX n/a XXX XXX XXX
EBITDA Margin -365% XXX -290% XXX XXX XXX
EBITDA Growth 24% XXX 0% XXX XXX XXX
Rule of 40 -643% XXX -317% XXX XXX XXX
Bessemer Rule of X XXX XXX -431% XXX XXX XXX
Revenue per Employee XXX XXX $0.3M XXX XXX XXX
Opex per Employee XXX XXX $1.4M XXX XXX XXX
S&M Expenses to Revenue XXX XXX n/a XXX XXX XXX
G&A Expenses to Revenue XXX XXX n/a XXX XXX XXX
R&D Expenses to Revenue XXX XXX 311% XXX XXX XXX
Opex to Revenue XXX XXX 429% XXX XXX XXX

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C4 Therapeutics Public Comps

See public comps and valuation multiples for Drug Development & Therapeutics and Small Molecules comps
EV/Revenue EV/EBITDA
2025E 2026E 2027E 2025E 2026E 2027E
Julphar XXX XXX XXX XXX XXX XXX
Benevolent AI XXX XXX XXX XXX XXX XXX
Galapagos XXX XXX XXX XXX XXX XXX
Pharming XXX XXX XXX XXX XXX XXX
Vivoryon Therapeutics XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX

Valuation data powered by FactSet, Inc.

C4 Therapeutics M&A and Investment Activity

C4 Therapeutics acquired  XXX companies to date.

Last acquisition by C4 Therapeutics was  XXXXXXXX, XXXXX XXXXX XXXXXX . C4 Therapeutics acquired  XXXXXXXX for  XXX (EV/Revenue multiple of  XXX ).

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Latest Acquisitions by C4 Therapeutics

Acquired Company EV EV/Revenue EV/EBITDA
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX

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About C4 Therapeutics

When was C4 Therapeutics founded? C4 Therapeutics was founded in 2015.
Where is C4 Therapeutics headquartered? C4 Therapeutics is headquartered in United States of America.
How many employees does C4 Therapeutics have? As of today, C4 Therapeutics has 110 employees.
Who is the CEO of C4 Therapeutics? C4 Therapeutics's CEO is Mr. Andrew J. Hirsch.
Is C4 Therapeutics publicy listed? Yes, C4 Therapeutics is a public company listed on NAS.
What is the stock symbol of C4 Therapeutics? C4 Therapeutics trades under CCCC ticker.
When did C4 Therapeutics go public? C4 Therapeutics went public in 2020.
Who are competitors of C4 Therapeutics? Similar companies to C4 Therapeutics include e.g. Julphar, Benevolent AI, Galapagos, Pharming.
What is the current market cap of C4 Therapeutics? C4 Therapeutics's current market cap is $88.8M
What is the current revenue of C4 Therapeutics? C4 Therapeutics's last 12 months revenue is $30.3M.
What is the current revenue growth of C4 Therapeutics? C4 Therapeutics revenue growth (NTM/LTM) is -26%.
What is the current EV/Revenue multiple of C4 Therapeutics? Current revenue multiple of C4 Therapeutics is -2.0x.
Is C4 Therapeutics profitable? Yes, C4 Therapeutics is EBITDA-positive (as of the last 12 months).
What is the current EBITDA of C4 Therapeutics? C4 Therapeutics's last 12 months EBITDA is -$110M.
What is C4 Therapeutics's EBITDA margin? C4 Therapeutics's last 12 months EBITDA margin is -365%.
What is the current EV/EBITDA multiple of C4 Therapeutics? Current EBITDA multiple of C4 Therapeutics is 0.6x.
What is the current FCF of C4 Therapeutics? C4 Therapeutics's last 12 months FCF is -$99.4M.
What is C4 Therapeutics's FCF margin? C4 Therapeutics's last 12 months FCF margin is -329%.
What is the current EV/FCF multiple of C4 Therapeutics? Current FCF multiple of C4 Therapeutics is 0.6x.

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