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Annexon Valuation Multiples

Discover revenue and EBITDA valuation multiples for Annexon and similar public comparables like Vivoryon Therapeutics, Pharming, and Galapagos.

Annexon Overview

About Annexon

Annexon Inc is a clinical-stage biopharmaceutical company developing a pipeline of novel therapies for patients with classical complement-mediated disorders of the body, brain, and eye. Its pipeline is based on its platform technology addressing well-researched classical complement-mediated autoimmune and neurodegenerative disease processes, both of which are triggered by aberrant activation of C1q. Its pipeline of product candidates is designed to block the activity of C1q and the entire classical complement pathway in a broad set of complement-mediated diseases. Its product candidates are ANX005, for autoimmune & neurodegenerative disorders; ANX007, for neurodegenerative ophthalmic disorders; ANX1502 for Oral small molecule; and ANX009, for systemic autoimmune diseases.


Founded

2011

HQ

United States of America
Employees

100

Website

annexonbio.com

Financials

LTM Revenue n/a

LTM EBITDA -$166M

EV

-$115M

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Annexon Financials

Annexon has a last 12-month revenue of n/a and a last 12-month EBITDA of -$166M.

In the most recent fiscal year, Annexon achieved revenue of n/a and an EBITDA of -$151M.

Annexon expects next 12-month revenue of  XXX    and NTM EBITDA of  XXX

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Annexon P&L

FY 2023 FY 2024 FY 2025 LTM NTM
Revenue n/a n/a XXX XXX XXX
Gross Profit n/a n/a XXX XXX XXX
Gross Margin NaN% NaN% XXX XXX XXX
EBITDA -$142M -$151M XXX XXX XXX
EBITDA Margin -Infinity% -Infinity% XXX XXX XXX
Net Profit -$142M -$134M XXX XXX XXX
Net Margin -Infinity% -Infinity% XXX XXX XXX
Net Debt n/a n/a XXX XXX XXX

Financial data powered by Morningstar, Inc.

Annexon Stock Performance

As of April 15, 2025, Annexon's stock price is $2.

Annexon has current market cap of $168M, and EV of -$115M.

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Annexon Stock Data

EV Market Cap Price 1D Price 1M Price 3M Price 12M EPS
-$115M $168M XXX XXX XXX XXX $-1.08

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Annexon Valuation Multiples

As of April 15, 2025, Annexon has market cap of $168M and EV of -$115M.

Annexon's trades at n/a LTM EV/Revenue multiple, and 0.7x LTM EBITDA.

Analysts estimate Annexon's 2025E EV/Revenue multiple at  XXX and 2025E EV/EBITDA multiple at  XXX

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Annexon Financial Valuation Multiples

FY 2024 FY 2025E FY 2026E FY 2027E
EV -$115M XXX XXX XXX
EV/Revenue n/a XXX XXX XXX
EV/EBITDA 0.8x XXX XXX XXX
P/E -1.2x XXX XXX XXX
P/E/Growth n/a XXX XXX XXX
EV/FCF 1.0x XXX XXX XXX

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Annexon Valuation Multiples

Annexon's NTM/LTM revenue growth is Infinity%

Annexon's revenue per employee for the last fiscal year averaged n/a, while opex per employee averaged $1.5M for the same period.

Over next 12 months, Annexon's ratio of sales and marketing spend to revenue is estimated to be  XXX , while its R&D spend to revenue to be  XXX .

Analysts estimate Annexon's 2025E EV/Revenue multiple at  XXX and 2025E EV/EBITDA multiple at  XXX

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Annexon Operational Valuation Multiples

FY 2024 NTM FY 2025E FY 2026E FY 2027E
Revenue Growth n/a XXX XXX XXX XXX
EBITDA Margin n/a XXX XXX XXX XXX
EBITDA Growth 7% XXX XXX XXX XXX
Rule of 40 (SaaS-only) n/a XXX XXX XXX XXX
Revenue per Employee n/a XXX XXX XXX XXX
Opex per Employee $1.5M XXX XXX XXX XXX
S&M Expenses to Revenue n/a XXX XXX XXX XXX
G&A Expenses to Revenue n/a XXX XXX XXX XXX
R&D Expenses to Revenue n/a XXX XXX XXX XXX
Opex to Revenue n/a XXX XXX XXX XXX

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Annexon Public Comps

See public comps and valuation multiples for Drug Development & Therapeutics and Biopharmaceuticals comps
EV/Revenue EV/EBITDA
2025E 2026E 2027E 2025E 2026E 2027E
Julphar XXX XXX XXX XXX XXX XXX
Benevolent AI XXX XXX XXX XXX XXX XXX
Galapagos XXX XXX XXX XXX XXX XXX
Pharming XXX XXX XXX XXX XXX XXX
Vivoryon Therapeutics XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX

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Annexon M&A and Investment Activity

Annexon acquired  XXX companies to date.

Last acquisition by Annexon was  XXXXXXXX, XXXXX XXXXX XXXXXX . Annexon acquired  XXXXXXXX for  XXX (EV/Revenue multiple of  XXX ).

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Latest Acquisitions by Annexon

Acquired Company EV EV/Revenue EV/EBITDA
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX

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About Annexon

When was Annexon founded? Annexon was founded in 2011.
Where is Annexon headquartered? Annexon is headquartered in United States of America.
How many employees does Annexon have? As of today, Annexon has 100 employees.
Who is the CEO of Annexon? Annexon's CEO is Mr. Douglas Love, Esq..
Is Annexon publicy listed? Yes, Annexon is a public company listed on NAS.
What is the stock symbol of Annexon? Annexon trades under ANNX ticker.
When did Annexon go public? Annexon went public in 2020.
Who are competitors of Annexon? Similar companies to Annexon include e.g. Julphar, Benevolent AI, Galapagos, Pharming.
What is the current market cap of Annexon? Annexon's current market cap is $168M
What is the current EBITDA of Annexon? Annexon's last 12-month EBITDA is -$166M.
What is the current EV/EBITDA multiple of Annexon? Current EBITDA multiple of Annexon is 0.7x.
Is Annexon profitable? Yes, Annexon is EBITDA-positive (as of the last 12 months).

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