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Xenon Pharmaceuticals Valuation Multiples

Discover revenue and EBITDA valuation multiples for Xenon Pharmaceuticals and similar public comparables like Chongqing Zhifei, Scholar Rock, SK Biopharmaceuticals, CRISPR Therapeutics and more.

Xenon Pharmaceuticals Overview

About Xenon Pharmaceuticals

Xenon Pharmaceuticals Inc is a neuroscience-focused biopharmaceutical company committed to improving the lives of people living with neurological and psychiatric disorders. It is advancing a novel product pipeline to address areas of high unmet medical need, including epilepsy and depression. The product candidates of the group include XEN1101, NBI-921352, and XEN496 for Epilepsy and Nav1.7 oral inhibitors for Pain.


Founded

1996

HQ

Canada

Employees

327

Financials (LTM)

Revenue: $7M
EBITDA: ($387M)

EV

$5B

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Xenon Pharmaceuticals Financials

Xenon Pharmaceuticals reported last 12-month revenue of $7M and negative EBITDA of ($387M).

In the same LTM period, Xenon Pharmaceuticals generated $7M in gross profit, ($387M) in EBITDA losses, and had net loss of ($368M).

Revenue (LTM)


Xenon Pharmaceuticals P&L

In the most recent fiscal year, Xenon Pharmaceuticals reported revenue of $8M and EBITDA of ($371M).

Xenon Pharmaceuticals expects next 12-month revenue of XXX and NTM EBITDA of XXX

See Xenon Pharmaceuticals forward-looking valuation multiples
LTMNTMLast FYFY 2026FY 2027FY 2028
Revenue$7MXXX$8MXXXXXXXXX
Gross Profit$7MXXX—XXXXXXXXX
Gross Margin100%XXX—XXXXXXXXX
EBITDA($387M)XXX($371M)XXXXXXXXX
EBITDA Margin(5895%)XXX(4940%)XXXXXXXXX
EBIT Margin(5992%)XXX(4974%)XXXXXXXXX
Net Profit($368M)XXX($346M)XXXXXXXXX
Net Margin(5606%)XXX(4612%)XXXXXXXXX

Financial data powered by Morningstar, Inc.

Xenon Pharmaceuticals Stock Performance

Xenon Pharmaceuticals has current market cap of $5B, and enterprise value of $5B.

Market Cap Evolution


Xenon Pharmaceuticals' stock price is $57.05.

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EVMarket CapPrice 1DPrice 1MPrice 3MPrice 12MEPS
$5B$5B-4.4%XXXXXXXXX$-3.62

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Xenon Pharmaceuticals Valuation Multiples

Xenon Pharmaceuticals trades at 747.2x EV/Revenue multiple, and (12.7x) EV/EBITDA.

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EV / Revenue (LTM)


Xenon Pharmaceuticals Financial Valuation Multiples

As of April 21, 2026, Xenon Pharmaceuticals has market cap of $5B and EV of $5B.

Equity research analysts estimate Xenon Pharmaceuticals' 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX

Xenon Pharmaceuticals has a P/E ratio of (14.8x).

LTMNTMLast FYFY 2026FY 2027FY 2028
Market cap (current)$5BXXX$5BXXXXXXXXX
EV (current)$5BXXX$5BXXXXXXXXX
EV/Revenue747.2xXXX653.8xXXXXXXXXX
EV/EBITDA(12.7x)XXX(13.2x)XXXXXXXXX
EV/EBIT(12.5x)XXX(13.1x)XXXXXXXXX
EV/Gross Profit747.2xXXX—XXXXXXXXX
P/E(14.8x)XXX(15.7x)XXXXXXXXX
EV/FCF(14.7x)XXX(17.5x)XXXXXXXXX

Valuation data powered by FactSet, Inc. and Morningstar, Inc.

Verified Xenon Pharmaceuticals Valuation Multiples

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Xenon Pharmaceuticals Margins & Growth Rates

Xenon Pharmaceuticals' revenue in the last 12 month grew by 275%.

Xenon Pharmaceuticals' revenue per employee in the last FY averaged $0.0M, while opex per employee averaged $1.2M for the same period.

Xenon Pharmaceuticals' rule of 40 is (9602%) (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Xenon Pharmaceuticals' rule of X is (9664%) (created by Bessemer, rule of X is another metric to measure SaaS companies, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

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Xenon Pharmaceuticals Operational Valuation Multiples

LTMNTMLast FYFY 2026FY 2027FY 2028
Revenue Growth275%XXX(41%)XXXXXXXXX
EBITDA Margin(5895%)XXX(4940%)XXXXXXXXX
EBITDA Growth8%XXX14%XXXXXXXXX
Rule of 40—XXX(9602%)XXXXXXXXX
Bessemer Rule of X—XXX(9664%)XXXXXXXXX
Revenue per Employee—XXX$0.0MXXXXXXXXX
Opex per Employee—XXX$1.2MXXXXXXXXX
G&A Expenses to Revenue1416%XXX1062%XXXXXXXXX
R&D Expenses to Revenue4740%XXX4013%XXXXXXXXX
Opex to Revenue—XXX5074%XXXXXXXXX

Valuation data powered by FactSet, Inc. and Morningstar, Inc.

Valuation Multiples Across 230+ Verticals

Xenon Pharmaceuticals Public Comps

See public comps and valuation multiples for other Biopharmaceuticals comps.

EV/RevenueEV/EBITDA
LTM2026E2027ELTM2026E2027E
Xenon PharmaceuticalsXXXXXXXXXXXXXXXXXX
Chongqing ZhifeiXXXXXXXXXXXXXXXXXX
Scholar RockXXXXXXXXXXXXXXXXXX
SK BiopharmaceuticalsXXXXXXXXXXXXXXXXXX
CRISPR TherapeuticsXXXXXXXXXXXXXXXXXX
Shanghai RAASXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX

Valuation data powered by FactSet, Inc.

Xenon Pharmaceuticals M&A Activity

Xenon Pharmaceuticals acquired XXX companies to date.

Last acquisition by Xenon Pharmaceuticals was on XXXXXXXX, XXXXX. Xenon Pharmaceuticals acquired XXXXXXXX for XXX (EV/Revenue multiple of XXX).

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Latest Acquisitions by Xenon Pharmaceuticals

Acquired CompanyValuationEV/RevenueEV/EBITDA
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX

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Xenon Pharmaceuticals Investment Activity

Xenon Pharmaceuticals invested in XXX companies to date.

Xenon Pharmaceuticals made its latest investment on XXXXXXXX, XXXXX. Xenon Pharmaceuticals invested in XXXXXXXX for XXX (EV/Revenue multiple of XXX).

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Latest Investments by Xenon Pharmaceuticals

CompanyValuationEV/RevenueEV/EBITDA
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX

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About Xenon Pharmaceuticals

When was Xenon Pharmaceuticals founded?Xenon Pharmaceuticals was founded in 1996.
Where is Xenon Pharmaceuticals headquartered?Xenon Pharmaceuticals is headquartered in Canada.
How many employees does Xenon Pharmaceuticals have?As of today, Xenon Pharmaceuticals has over 327 employees.
Who is the CEO of Xenon Pharmaceuticals?Xenon Pharmaceuticals' CEO is Ian C. Mortimer.
Is Xenon Pharmaceuticals publicly listed?Yes, Xenon Pharmaceuticals is a public company listed on Nasdaq.
What is the stock symbol of Xenon Pharmaceuticals?Xenon Pharmaceuticals trades under XENE ticker.
When did Xenon Pharmaceuticals go public?Xenon Pharmaceuticals went public in 2014.
Who are competitors of Xenon Pharmaceuticals?Xenon Pharmaceuticals main competitors are Chongqing Zhifei, Scholar Rock, SK Biopharmaceuticals, CRISPR Therapeutics.
What is the current market cap of Xenon Pharmaceuticals?Xenon Pharmaceuticals' current market cap is $5B.
What is the current revenue of Xenon Pharmaceuticals?Xenon Pharmaceuticals' last 12 months revenue is $7M.
What is the current revenue growth of Xenon Pharmaceuticals?Xenon Pharmaceuticals revenue growth (NTM/LTM) is 275%.
What is the current EV/Revenue multiple of Xenon Pharmaceuticals?Current revenue multiple of Xenon Pharmaceuticals is 747.2x.
Is Xenon Pharmaceuticals profitable?No, Xenon Pharmaceuticals is not profitable.
What is the current EBITDA of Xenon Pharmaceuticals?Xenon Pharmaceuticals has negative EBITDA and is not profitable.
What is Xenon Pharmaceuticals' EBITDA margin?Xenon Pharmaceuticals' last 12 months EBITDA margin is (5895%).
What is the current EV/EBITDA multiple of Xenon Pharmaceuticals?Current EBITDA multiple of Xenon Pharmaceuticals is (12.7x).
What is the current FCF of Xenon Pharmaceuticals?Xenon Pharmaceuticals' last 12 months FCF is ($334M).
What is Xenon Pharmaceuticals' FCF margin?Xenon Pharmaceuticals' last 12 months FCF margin is (5093%).
What is the current EV/FCF multiple of Xenon Pharmaceuticals?Current FCF multiple of Xenon Pharmaceuticals is (14.7x).

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