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VYNE Therapeutics Inc is a biopharmaceutical company focused on developing proprietary, innovative and differentiated therapies for the treatment of immuno-inflammatory conditions. Its advanced product candidate is FMX114, which is being evaluated for the potential treatment of mild-to-moderate AD (atopic dermatitis). The company is also in the pre-clinical stages of developing products containing BET (Bromodomain and Extra-Terminal Domain) inhibitor compounds. Its products include AMZEEQ, ZILXI, and FCD105.
2011
13
LTM Revenue $0.4M
LTM EBITDA -$47.3M
-$34.8M
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VYNE Therapeutics has a last 12-month revenue of $0.4M and a last 12-month EBITDA of -$47.3M.
In the most recent fiscal year, VYNE Therapeutics achieved revenue of $0.5M and an EBITDA of -$43.6M.
VYNE Therapeutics expects next 12-month revenue of XXX and NTM EBITDA of XXX
See VYNE Therapeutics valuation multiples based on analyst estimates| FY 2023 | FY 2024 | FY 2025 | LTM | NTM | |
|---|---|---|---|---|---|
| Revenue | $0.4M | $0.5M | XXX | XXX | XXX |
| Gross Profit | n/a | n/a | XXX | XXX | XXX |
| Gross Margin | NaN% | NaN% | XXX | XXX | XXX |
| EBITDA | -$29.3M | -$43.6M | XXX | XXX | XXX |
| EBITDA Margin | -6900% | -8709% | XXX | XXX | XXX |
| Net Profit | -$23.2M | -$28.5M | XXX | XXX | XXX |
| Net Margin | -5474% | -5679% | XXX | XXX | XXX |
| Net Debt | n/a | n/a | XXX | XXX | XXX |
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As of April 15, 2025, VYNE Therapeutics's stock price is $2.
VYNE Therapeutics has current market cap of $26.6M, and EV of -$34.8M.
See VYNE Therapeutics trading valuation data| EV | Market Cap | Price 1D | Price 1M | Price 3M | Price 12M | EPS |
|---|---|---|---|---|---|---|
| -$34.8M | $26.6M | XXX | XXX | XXX | XXX | $-1.00 |
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Sign UpAs of April 15, 2025, VYNE Therapeutics has market cap of $26.6M and EV of -$34.8M.
VYNE Therapeutics's trades at -84.0x LTM EV/Revenue multiple, and 0.7x LTM EBITDA.
Analysts estimate VYNE Therapeutics's 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX
See valuation multiples for VYNE Therapeutics and 10K+ public comps| FY 2024 | FY 2025E | FY 2026E | FY 2027E | |
|---|---|---|---|---|
| EV | -$34.8M | XXX | XXX | XXX |
| EV/Revenue | -69.5x | XXX | XXX | XXX |
| EV/EBITDA | 0.8x | XXX | XXX | XXX |
| P/E | -0.7x | XXX | XXX | XXX |
| P/E/Growth | n/a | XXX | XXX | XXX |
| EV/FCF | 1.0x | XXX | XXX | XXX |
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Access all public comps and forward-looking valuation multiples like EV/Revenue in 2025, based on equity research analyst estimates.
Sign UpVYNE Therapeutics's NTM/LTM revenue growth is -52%
VYNE Therapeutics's revenue per employee for the last fiscal year averaged $39K, while opex per employee averaged $3.4M for the same period.
Over next 12 months, VYNE Therapeutics's ratio of sales and marketing spend to revenue is estimated to be XXX , while its R&D spend to revenue to be XXX .
Analysts estimate VYNE Therapeutics's 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX
See operational valuation multiples for VYNE Therapeutics and other 10K+ public comps| FY 2024 | NTM | FY 2025E | FY 2026E | FY 2027E | |
|---|---|---|---|---|---|
| Revenue Growth | 18% | XXX | XXX | XXX | XXX |
| EBITDA Margin | -8709% | XXX | XXX | XXX | XXX |
| EBITDA Growth | 49% | XXX | XXX | XXX | XXX |
| Rule of 40 (SaaS-only) | -8761% | XXX | XXX | XXX | XXX |
| Revenue per Employee | $39K | XXX | XXX | XXX | XXX |
| Opex per Employee | $3.4M | XXX | XXX | XXX | XXX |
| S&M Expenses to Revenue | n/a | XXX | XXX | XXX | XXX |
| G&A Expenses to Revenue | 2633% | XXX | XXX | XXX | XXX |
| R&D Expenses to Revenue | 6177% | XXX | XXX | XXX | XXX |
| Opex to Revenue | 8810% | XXX | XXX | XXX | XXX |
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| EV/Revenue | EV/EBITDA | |||||
|---|---|---|---|---|---|---|
| 2025E | 2026E | 2027E | 2025E | 2026E | 2027E | |
| Julphar | XXX | XXX | XXX | XXX | XXX | XXX |
| Benevolent AI | XXX | XXX | XXX | XXX | XXX | XXX |
| Galapagos | XXX | XXX | XXX | XXX | XXX | XXX |
| Pharming | XXX | XXX | XXX | XXX | XXX | XXX |
| Vivoryon Therapeutics | XXX | XXX | XXX | XXX | XXX | XXX |
| XXXXXXXX | XXX | XXX | XXX | XXX | XXX | XXX |
| XXXXXXXX | XXX | XXX | XXX | XXX | XXX | XXX |
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VYNE Therapeutics acquired XXX companies to date.
Last acquisition by VYNE Therapeutics was XXXXXXXX, XXXXX XXXXX XXXXXX . VYNE Therapeutics acquired XXXXXXXX for XXX (EV/Revenue multiple of XXX ).
See M&A valuation multiples| Acquired Company | EV | EV/Revenue | EV/EBITDA |
|---|---|---|---|
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXX | XXX | XXX | XXX |
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Sign Up| When was VYNE Therapeutics founded? | VYNE Therapeutics was founded in 2011. |
| Where is VYNE Therapeutics headquartered? | VYNE Therapeutics is headquartered in United States of America. |
| How many employees does VYNE Therapeutics have? | As of today, VYNE Therapeutics has 13 employees. |
| Who is the CEO of VYNE Therapeutics? | VYNE Therapeutics's CEO is Mr. David Domzalski. |
| Is VYNE Therapeutics publicy listed? | Yes, VYNE Therapeutics is a public company listed on NAS. |
| What is the stock symbol of VYNE Therapeutics? | VYNE Therapeutics trades under VYNE ticker. |
| When did VYNE Therapeutics go public? | VYNE Therapeutics went public in 2018. |
| Who are competitors of VYNE Therapeutics? | Similar companies to VYNE Therapeutics include e.g. Julphar, Benevolent AI, Galapagos, Pharming. |
| What is the current market cap of VYNE Therapeutics? | VYNE Therapeutics's current market cap is $26.6M |
| What is the current revenue of VYNE Therapeutics? | VYNE Therapeutics's last 12-month revenue is $0.4M. |
| What is the current EBITDA of VYNE Therapeutics? | VYNE Therapeutics's last 12-month EBITDA is -$47.3M. |
| What is the current EV/Revenue multiple of VYNE Therapeutics? | Current revenue multiple of VYNE Therapeutics is -84.0x. |
| What is the current EV/EBITDA multiple of VYNE Therapeutics? | Current EBITDA multiple of VYNE Therapeutics is 0.7x. |
| What is the current revenue growth of VYNE Therapeutics? | VYNE Therapeutics revenue growth between 2023 and 2024 was 18%. |
| Is VYNE Therapeutics profitable? | Yes, VYNE Therapeutics is EBITDA-positive (as of the last 12 months). |
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