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Ultragenyx Valuation Multiples

Discover revenue and EBITDA valuation multiples for Ultragenyx and similar public comparables like Galapagos, Julphar, and Pharming.

Ultragenyx Overview

About Ultragenyx

Ultragenyx Pharmaceutical Inc is a USA-based biopharmaceutical company. It identifies, acquires, develops, and commercializes novel products for the treatment of serious rare and ultra-rare diseases, with a focus on serious, debilitating genetic diseases. The company's medicine portfolio includes Crysvita, Dojolvi and Mepsevii. Crysvita is indicated for the treatment of X-linked hypophosphatemia (XLH) in adult and pediatric patients 1 year of age and older. Mepsevii is indicated in pediatric and adult patients for the treatment of Mucopolysaccharidosis VII.


Founded

2010

HQ

United States of America
Employees

1.3K+

Website

ultragenyx.com

Financials

LTM Revenue $599M

LTM EBITDA -$455M

EV

$2.8B

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Ultragenyx Financials

Ultragenyx has a last 12-month revenue (LTM) of $599M and a last 12-month EBITDA of -$455M.

In the most recent fiscal year, Ultragenyx achieved revenue of $560M and an EBITDA of -$469M.

Ultragenyx expects next 12-month revenue of  XXX    and NTM EBITDA of  XXX

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Ultragenyx P&L

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue $599M XXX $560M XXX XXX XXX
Gross Profit $513M XXX $484M XXX XXX XXX
Gross Margin 86% XXX 86% XXX XXX XXX
EBITDA -$455M XXX -$469M XXX XXX XXX
EBITDA Margin -76% XXX -84% XXX XXX XXX
EBIT -$501M XXX -$536M XXX XXX XXX
EBIT Margin -84% XXX -96% XXX XXX XXX
Net Profit -$536M XXX -$569M XXX XXX XXX
Net Margin -89% XXX -102% XXX XXX XXX
Net Debt XXX XXX n/a XXX XXX XXX

Financial data powered by Morningstar, Inc.

Ultragenyx Stock Performance

As of May 30, 2025, Ultragenyx's stock price is $34.

Ultragenyx has current market cap of $3.2B, and EV of $2.8B.

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Ultragenyx Stock Data

EV Market Cap Price 1D Price 1M Price 3M Price 12M EPS
$2.8B $3.2B XXX XXX XXX XXX $-5.76

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Ultragenyx Valuation Multiples

As of May 30, 2025, Ultragenyx has market cap of $3.2B and EV of $2.8B.

Ultragenyx's trades at 4.9x EV/Revenue multiple, and -5.9x EV/EBITDA.

Equity research analysts estimate Ultragenyx's 2025E EV/Revenue multiple at  XXX and 2025E EV/EBITDA multiple at  XXX

Ultragenyx has a P/E ratio of -6.0x.

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Ultragenyx Financial Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Market cap (current) $3.2B XXX $3.2B XXX XXX XXX
EV (current) $2.8B XXX $2.8B XXX XXX XXX
EV/Revenue 4.6x XXX 4.9x XXX XXX XXX
EV/EBITDA -6.1x XXX -5.9x XXX XXX XXX
EV/EBIT -5.5x XXX -5.2x XXX XXX XXX
EV/Gross Profit 5.4x XXX n/a XXX XXX XXX
P/E -6.0x XXX -5.7x XXX XXX XXX
EV/FCF 27.6x XXX -6.4x XXX XXX XXX

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Ultragenyx Margins & Growth Rates

Ultragenyx's last 12 month revenue growth is 22%

Ultragenyx's revenue per employee in the last FY averaged $0.4M, while opex per employee averaged $0.8M for the same period.

Ultragenyx's rule of 40 is -97% (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Ultragenyx's rule of X is -21% (created by Bessemer, rule of X is another metric relevant for SaaS companies only, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

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Ultragenyx Operational Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue Growth 22% XXX 22% XXX XXX XXX
EBITDA Margin -76% XXX -84% XXX XXX XXX
EBITDA Growth -25% XXX n/a XXX XXX XXX
Rule of 40 -97% XXX -62% XXX XXX XXX
Bessemer Rule of X XXX XXX -21% XXX XXX XXX
Revenue per Employee XXX XXX $0.4M XXX XXX XXX
Opex per Employee XXX XXX $0.8M XXX XXX XXX
S&M Expenses to Revenue XXX XXX n/a XXX XXX XXX
G&A Expenses to Revenue XXX XXX n/a XXX XXX XXX
R&D Expenses to Revenue XXX XXX 125% XXX XXX XXX
Opex to Revenue XXX XXX 182% XXX XXX XXX

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Ultragenyx Public Comps

See public comps and valuation multiples for Drug Development & Therapeutics comps
EV/Revenue EV/EBITDA
2025E 2026E 2027E 2025E 2026E 2027E
Julphar XXX XXX XXX XXX XXX XXX
Benevolent AI XXX XXX XXX XXX XXX XXX
Galapagos XXX XXX XXX XXX XXX XXX
Pharming XXX XXX XXX XXX XXX XXX
Vivoryon Therapeutics XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX

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Ultragenyx M&A and Investment Activity

Ultragenyx acquired  XXX companies to date.

Last acquisition by Ultragenyx was  XXXXXXXX, XXXXX XXXXX XXXXXX . Ultragenyx acquired  XXXXXXXX for  XXX (EV/Revenue multiple of  XXX ).

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Latest Acquisitions by Ultragenyx

Acquired Company EV EV/Revenue EV/EBITDA
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX

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About Ultragenyx

When was Ultragenyx founded? Ultragenyx was founded in 2010.
Where is Ultragenyx headquartered? Ultragenyx is headquartered in United States of America.
How many employees does Ultragenyx have? As of today, Ultragenyx has 1.3K+ employees.
Who is the CEO of Ultragenyx? Ultragenyx's CEO is Dr. Emil D. Kakkis, M.D.,PhD.
Is Ultragenyx publicy listed? Yes, Ultragenyx is a public company listed on NAS.
What is the stock symbol of Ultragenyx? Ultragenyx trades under RARE ticker.
When did Ultragenyx go public? Ultragenyx went public in 2014.
Who are competitors of Ultragenyx? Similar companies to Ultragenyx include e.g. Julphar, Benevolent AI, Galapagos, Pharming.
What is the current market cap of Ultragenyx? Ultragenyx's current market cap is $3.2B
What is the current revenue of Ultragenyx? Ultragenyx's last 12 months revenue is $599M.
What is the current revenue growth of Ultragenyx? Ultragenyx revenue growth (NTM/LTM) is 22%.
What is the current EV/Revenue multiple of Ultragenyx? Current revenue multiple of Ultragenyx is 4.6x.
Is Ultragenyx profitable? Yes, Ultragenyx is EBITDA-positive (as of the last 12 months).
What is the current EBITDA of Ultragenyx? Ultragenyx's last 12 months EBITDA is -$455M.
What is Ultragenyx's EBITDA margin? Ultragenyx's last 12 months EBITDA margin is -76%.
What is the current EV/EBITDA multiple of Ultragenyx? Current EBITDA multiple of Ultragenyx is -6.1x.
What is the current FCF of Ultragenyx? Ultragenyx's last 12 months FCF is $100M.
What is Ultragenyx's FCF margin? Ultragenyx's last 12 months FCF margin is 17%.
What is the current EV/FCF multiple of Ultragenyx? Current FCF multiple of Ultragenyx is 27.6x.

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