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Third Harmonic Bio Valuation Multiples

Discover revenue and EBITDA valuation multiples for Third Harmonic Bio and similar public comparables like Vivoryon Therapeutics, Julphar, and Pharming.

Third Harmonic Bio Overview

About Third Harmonic Bio

Third Harmonic Bio Inc is a biopharmaceutical company focused on the development of the next wave of medicine for the treatment of inflammatory diseases, including dermal, respiratory, and gastrointestinal diseases. The company’s product candidate, THB001, is a selective, oral small-molecule inhibitor of KIT, a cell surface receptor that serves as the master regulator of mast cell function and survival. Its other product candidate THB335, is a potent, selective, oral small molecule KIT inhibitor, for the treatment of multiple mast cell-driven inflammatory diseases of the skin, airway, and gastrointestinal tract.


Founded

2019

HQ

United States of America
Employees

53

Financials

Last FY Revenue n/a

Last FY EBITDA -$58.8M

EV

-$33.9M

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Third Harmonic Bio Financials

In the most recent fiscal year, Third Harmonic Bio achieved revenue of n/a and an EBITDA of -$58.8M.

Third Harmonic Bio expects next 12-month revenue of  XXX    and NTM EBITDA of  XXX

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Third Harmonic Bio P&L

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue n/a XXX n/a XXX XXX XXX
Gross Profit n/a XXX n/a XXX XXX XXX
Gross Margin n/a XXX n/a XXX XXX XXX
EBITDA n/a XXX -$58.8M XXX XXX XXX
EBITDA Margin n/a XXX n/a XXX XXX XXX
EBIT n/a XXX -$58.9M XXX XXX XXX
EBIT Margin n/a XXX n/a XXX XXX XXX
Net Profit -$45.5M XXX -$45.5M XXX XXX XXX
Net Margin n/a XXX n/a XXX XXX XXX
Net Debt XXX XXX n/a XXX XXX XXX

Financial data powered by Morningstar, Inc.

Third Harmonic Bio Stock Performance

As of May 30, 2025, Third Harmonic Bio's stock price is $5.

Third Harmonic Bio has current market cap of $235M, and EV of -$33.9M.

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Third Harmonic Bio Stock Data

EV Market Cap Price 1D Price 1M Price 3M Price 12M EPS
-$33.9M $235M XXX XXX XXX XXX $-1.09

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Third Harmonic Bio Valuation Multiples

As of May 30, 2025, Third Harmonic Bio has market cap of $235M and EV of -$33.9M.

Third Harmonic Bio's trades at n/a EV/Revenue multiple, and 0.6x EV/EBITDA.

Equity research analysts estimate Third Harmonic Bio's 2025E EV/Revenue multiple at  XXX and 2025E EV/EBITDA multiple at  XXX

Third Harmonic Bio has a P/E ratio of -5.2x.

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Third Harmonic Bio Financial Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Market cap (current) $235M XXX $235M XXX XXX XXX
EV (current) -$33.9M XXX -$33.9M XXX XXX XXX
EV/Revenue n/a XXX n/a XXX XXX XXX
EV/EBITDA n/a XXX 0.6x XXX XXX XXX
EV/EBIT n/a XXX 0.6x XXX XXX XXX
EV/Gross Profit n/a XXX n/a XXX XXX XXX
P/E -5.2x XXX -5.2x XXX XXX XXX
EV/FCF n/a XXX 1.0x XXX XXX XXX

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Third Harmonic Bio Margins & Growth Rates

Third Harmonic Bio's revenue per employee in the last FY averaged n/a, while opex per employee averaged $1.1M for the same period.

Third Harmonic Bio's rule of 40 is unknown (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Third Harmonic Bio's rule of X is unknown (created by Bessemer, rule of X is another metric relevant for SaaS companies only, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

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Third Harmonic Bio Operational Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue Growth n/a XXX n/a XXX XXX XXX
EBITDA Margin n/a XXX n/a XXX XXX XXX
EBITDA Growth n/a XXX n/a XXX XXX XXX
Rule of 40 n/a XXX n/a XXX XXX XXX
Bessemer Rule of X XXX XXX n/a XXX XXX XXX
Revenue per Employee XXX XXX n/a XXX XXX XXX
Opex per Employee XXX XXX $1.1M XXX XXX XXX
S&M Expenses to Revenue XXX XXX n/a XXX XXX XXX
G&A Expenses to Revenue XXX XXX n/a XXX XXX XXX
R&D Expenses to Revenue XXX XXX n/a XXX XXX XXX
Opex to Revenue XXX XXX n/a XXX XXX XXX

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Third Harmonic Bio Public Comps

See public comps and valuation multiples for Drug Development & Therapeutics and Biopharmaceuticals comps
EV/Revenue EV/EBITDA
2025E 2026E 2027E 2025E 2026E 2027E
Julphar XXX XXX XXX XXX XXX XXX
Benevolent AI XXX XXX XXX XXX XXX XXX
Galapagos XXX XXX XXX XXX XXX XXX
Pharming XXX XXX XXX XXX XXX XXX
Vivoryon Therapeutics XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX

Valuation data powered by FactSet, Inc.

Third Harmonic Bio M&A and Investment Activity

Third Harmonic Bio acquired  XXX companies to date.

Last acquisition by Third Harmonic Bio was  XXXXXXXX, XXXXX XXXXX XXXXXX . Third Harmonic Bio acquired  XXXXXXXX for  XXX (EV/Revenue multiple of  XXX ).

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Latest Acquisitions by Third Harmonic Bio

Acquired Company EV EV/Revenue EV/EBITDA
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX

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About Third Harmonic Bio

When was Third Harmonic Bio founded? Third Harmonic Bio was founded in 2019.
Where is Third Harmonic Bio headquartered? Third Harmonic Bio is headquartered in United States of America.
How many employees does Third Harmonic Bio have? As of today, Third Harmonic Bio has 53 employees.
Who is the CEO of Third Harmonic Bio? Third Harmonic Bio's CEO is Ms. Natalie C. Holles.
Is Third Harmonic Bio publicy listed? Yes, Third Harmonic Bio is a public company listed on NAS.
What is the stock symbol of Third Harmonic Bio? Third Harmonic Bio trades under THRD ticker.
When did Third Harmonic Bio go public? Third Harmonic Bio went public in 2022.
Who are competitors of Third Harmonic Bio? Similar companies to Third Harmonic Bio include e.g. Julphar, Benevolent AI, Galapagos, Pharming.
What is the current market cap of Third Harmonic Bio? Third Harmonic Bio's current market cap is $235M
Is Third Harmonic Bio profitable? Yes, Third Harmonic Bio is EBITDA-positive (as of the last 12 months).

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