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Scilex Holding Valuation Multiples

Discover revenue and EBITDA valuation multiples for Scilex Holding and similar public comparables like Pharming, Galapagos, and Vivoryon Therapeutics.

Scilex Holding Overview

About Scilex Holding

Scilex Holding Co is focused on acquiring, developing, and commercializing non-opioid pain management products for the treatment of acute and chronic pain. The Company's commercial product, ZTlido (lidocaine topical system), is a prescription lidocaine topical product for relieving pain associated with postherpetic neuralgia, which is a form of post-shingles nerve pain. It is focused on commercializing Gloperba (colchicine USP) an oral solution, a prophylactic treatment for painful gout flares in adults. The Company's three product candidates are SP-102 or SEMDEXA viscous gel formulation of a used corticosteroid for epidural injections, SP-103 a Phase 2, triple-strength formulation of ZTlido, and SP-104, 4.5 mg Delayed Burst Release Low Dose Naltrexone Hydrochloride (DBR-LDN) Capsule.


Founded

2009

HQ

United States of America
Employees

115

Financials

LTM Revenue $76.6M

Last FY EBITDA -$66.8M

EV

$63.8M

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Scilex Holding Financials

Scilex Holding has a last 12-month revenue (LTM) of $76.6M and a last 12-month EBITDA of n/a.

In the most recent fiscal year, Scilex Holding achieved revenue of $56.6M and an EBITDA of -$66.8M.

Scilex Holding expects next 12-month revenue of  XXX    and NTM EBITDA of  XXX

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Scilex Holding P&L

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue $76.6M XXX $56.6M XXX XXX XXX
Gross Profit $55.9M XXX $39.9M XXX XXX XXX
Gross Margin 73% XXX 71% XXX XXX XXX
EBITDA n/a XXX -$66.8M XXX XXX XXX
EBITDA Margin n/a XXX -118% XXX XXX XXX
EBIT -$69.2M XXX -$92.8M XXX XXX XXX
EBIT Margin -90% XXX -164% XXX XXX XXX
Net Profit -$62.2M XXX -$72.8M XXX XXX XXX
Net Margin -81% XXX -129% XXX XXX XXX
Net Debt XXX XXX $32.4M XXX XXX XXX

Financial data powered by Morningstar, Inc.

Scilex Holding Stock Performance

As of May 30, 2025, Scilex Holding's stock price is $5.

Scilex Holding has current market cap of $28.1M, and EV of $63.8M.

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Scilex Holding Stock Data

EV Market Cap Price 1D Price 1M Price 3M Price 12M EPS
$63.8M $28.1M XXX XXX XXX XXX $-1.96

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Scilex Holding Valuation Multiples

As of May 30, 2025, Scilex Holding has market cap of $28.1M and EV of $63.8M.

Scilex Holding's trades at 1.1x EV/Revenue multiple, and -1.0x EV/EBITDA.

Equity research analysts estimate Scilex Holding's 2025E EV/Revenue multiple at  XXX and 2025E EV/EBITDA multiple at  XXX

Scilex Holding has a P/E ratio of -0.5x.

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Scilex Holding Financial Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Market cap (current) $28.1M XXX $28.1M XXX XXX XXX
EV (current) $63.8M XXX $63.8M XXX XXX XXX
EV/Revenue 0.8x XXX 1.1x XXX XXX XXX
EV/EBITDA n/a XXX -1.0x XXX XXX XXX
EV/EBIT -0.9x XXX -0.7x XXX XXX XXX
EV/Gross Profit 1.1x XXX n/a XXX XXX XXX
P/E -0.5x XXX -0.4x XXX XXX XXX
EV/FCF n/a XXX 3.4x XXX XXX XXX

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Scilex Holding Margins & Growth Rates

Scilex Holding's last 12 month revenue growth is 153%

Scilex Holding's revenue per employee in the last FY averaged $0.5M, while opex per employee averaged $1.2M for the same period.

Scilex Holding's rule of 40 is -81% (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Scilex Holding's rule of X is unknown (created by Bessemer, rule of X is another metric relevant for SaaS companies only, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

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Scilex Holding Operational Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue Growth 153% XXX 137% XXX XXX XXX
EBITDA Margin n/a XXX -118% XXX XXX XXX
EBITDA Growth n/a XXX n/a XXX XXX XXX
Rule of 40 -81% XXX 35% XXX XXX XXX
Bessemer Rule of X XXX XXX n/a XXX XXX XXX
Revenue per Employee XXX XXX $0.5M XXX XXX XXX
Opex per Employee XXX XXX $1.2M XXX XXX XXX
S&M Expenses to Revenue XXX XXX n/a XXX XXX XXX
G&A Expenses to Revenue XXX XXX n/a XXX XXX XXX
R&D Expenses to Revenue XXX XXX 17% XXX XXX XXX
Opex to Revenue XXX XXX 234% XXX XXX XXX

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Scilex Holding Public Comps

See public comps and valuation multiples for Drug Development & Therapeutics comps
EV/Revenue EV/EBITDA
2025E 2026E 2027E 2025E 2026E 2027E
Julphar XXX XXX XXX XXX XXX XXX
Benevolent AI XXX XXX XXX XXX XXX XXX
Galapagos XXX XXX XXX XXX XXX XXX
Pharming XXX XXX XXX XXX XXX XXX
Vivoryon Therapeutics XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX

Valuation data powered by FactSet, Inc.

Scilex Holding M&A and Investment Activity

Scilex Holding acquired  XXX companies to date.

Last acquisition by Scilex Holding was  XXXXXXXX, XXXXX XXXXX XXXXXX . Scilex Holding acquired  XXXXXXXX for  XXX (EV/Revenue multiple of  XXX ).

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Latest Acquisitions by Scilex Holding

Acquired Company EV EV/Revenue EV/EBITDA
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX

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About Scilex Holding

When was Scilex Holding founded? Scilex Holding was founded in 2009.
Where is Scilex Holding headquartered? Scilex Holding is headquartered in United States of America.
How many employees does Scilex Holding have? As of today, Scilex Holding has 115 employees.
Who is the CEO of Scilex Holding? Scilex Holding's CEO is Mr. Jaisim Shah.
Is Scilex Holding publicy listed? Yes, Scilex Holding is a public company listed on NAS.
What is the stock symbol of Scilex Holding? Scilex Holding trades under SCLX ticker.
When did Scilex Holding go public? Scilex Holding went public in 2022.
Who are competitors of Scilex Holding? Similar companies to Scilex Holding include e.g. Julphar, Benevolent AI, Galapagos, Pharming.
What is the current market cap of Scilex Holding? Scilex Holding's current market cap is $28.1M
What is the current revenue of Scilex Holding? Scilex Holding's last 12 months revenue is $76.6M.
What is the current revenue growth of Scilex Holding? Scilex Holding revenue growth (NTM/LTM) is 153%.
What is the current EV/Revenue multiple of Scilex Holding? Current revenue multiple of Scilex Holding is 0.8x.
Is Scilex Holding profitable? Yes, Scilex Holding is EBITDA-positive (as of the last 12 months).

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