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Axsome Therapeutics Valuation Multiples

Discover revenue and EBITDA valuation multiples for Axsome Therapeutics and similar public comparables like Pharming, Benevolent AI, and Julphar.

Axsome Therapeutics Overview

About Axsome Therapeutics

Axsome Therapeutics Inc is a clinical-stage biopharmaceutical company. It is engaged in developing novel therapies for the management of the central nervous system, or CNS, disorders for which there are limited treatment options. Its pipeline products includes AXS-05, AXS-07, AXS-12, and AXS-14. It manages its business as one operating segment and reporting unit, which is the business of developing and delivering novel therapies for the management of CNS disorders.


Founded

2012

HQ

United States of America
Employees

683

Website

axsome.com

Financials

LTM Revenue $457M

LTM EBITDA -$219M

EV

$4.9B

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Axsome Therapeutics Financials

Axsome Therapeutics has a last 12-month revenue of $457M and a last 12-month EBITDA of -$219M.

In the most recent fiscal year, Axsome Therapeutics achieved revenue of $386M and an EBITDA of -$273M.

Axsome Therapeutics expects next 12-month revenue of  XXX    and NTM EBITDA of  XXX

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Axsome Therapeutics P&L

FY 2023 FY 2024 FY 2025 LTM NTM
Revenue $271M $386M XXX XXX XXX
Gross Profit $44.8M $245M XXX XXX XXX
Gross Margin 17% 63% XXX XXX XXX
EBITDA -$225M -$273M XXX XXX XXX
EBITDA Margin -83% -71% XXX XXX XXX
Net Profit -$187M -$239M XXX XXX XXX
Net Margin -69% -62% XXX XXX XXX
Net Debt n/a n/a XXX XXX XXX

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Axsome Therapeutics Stock Performance

As of April 23, 2025, Axsome Therapeutics's stock price is $104.

Axsome Therapeutics has current market cap of $5.1B, and EV of $4.9B.

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Axsome Therapeutics Stock Data

EV Market Cap Price 1D Price 1M Price 3M Price 12M EPS
$4.9B $5.1B XXX XXX XXX XXX $-5.11

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Axsome Therapeutics Valuation Multiples

As of April 23, 2025, Axsome Therapeutics has market cap of $5.1B and EV of $4.9B.

Axsome Therapeutics's trades at 10.8x LTM EV/Revenue multiple, and -22.6x LTM EBITDA.

Analysts estimate Axsome Therapeutics's 2025E EV/Revenue multiple at  XXX and 2025E EV/EBITDA multiple at  XXX

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Axsome Therapeutics Financial Valuation Multiples

FY 2024 FY 2025E FY 2026E FY 2027E
EV $4.9B XXX XXX XXX
EV/Revenue 12.8x XXX XXX XXX
EV/EBITDA -18.1x XXX XXX XXX
P/E -17.6x XXX XXX XXX
P/E/Growth n/a XXX XXX XXX
EV/FCF -38.4x XXX XXX XXX

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Axsome Therapeutics Valuation Multiples

Axsome Therapeutics's NTM/LTM revenue growth is 61%

Axsome Therapeutics's revenue per employee for the last fiscal year averaged $0.6M, while opex per employee averaged $0.9M for the same period.

Over next 12 months, Axsome Therapeutics's ratio of sales and marketing spend to revenue is estimated to be  XXX , while its R&D spend to revenue to be  XXX .

Analysts estimate Axsome Therapeutics's 2025E EV/Revenue multiple at  XXX and 2025E EV/EBITDA multiple at  XXX

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Axsome Therapeutics Operational Valuation Multiples

FY 2024 NTM FY 2025E FY 2026E FY 2027E
Revenue Growth 43% XXX XXX XXX XXX
EBITDA Margin -71% XXX XXX XXX XXX
EBITDA Growth 21% XXX XXX XXX XXX
Rule of 40 (SaaS-only) -9% XXX XXX XXX XXX
Revenue per Employee $0.6M XXX XXX XXX XXX
Opex per Employee $0.9M XXX XXX XXX XXX
S&M Expenses to Revenue n/a XXX XXX XXX XXX
G&A Expenses to Revenue n/a XXX XXX XXX XXX
R&D Expenses to Revenue 49% XXX XXX XXX XXX
Opex to Revenue 157% XXX XXX XXX XXX

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Axsome Therapeutics Public Comps

See public comps and valuation multiples for Drug Development & Therapeutics comps
EV/Revenue EV/EBITDA
2025E 2026E 2027E 2025E 2026E 2027E
Julphar XXX XXX XXX XXX XXX XXX
Benevolent AI XXX XXX XXX XXX XXX XXX
Galapagos XXX XXX XXX XXX XXX XXX
Pharming XXX XXX XXX XXX XXX XXX
Vivoryon Therapeutics XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX

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Axsome Therapeutics M&A and Investment Activity

Axsome Therapeutics acquired  XXX companies to date.

Last acquisition by Axsome Therapeutics was  XXXXXXXX, XXXXX XXXXX XXXXXX . Axsome Therapeutics acquired  XXXXXXXX for  XXX (EV/Revenue multiple of  XXX ).

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Latest Acquisitions by Axsome Therapeutics

Acquired Company EV EV/Revenue EV/EBITDA
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX

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About Axsome Therapeutics

When was Axsome Therapeutics founded? Axsome Therapeutics was founded in 2012.
Where is Axsome Therapeutics headquartered? Axsome Therapeutics is headquartered in United States of America.
How many employees does Axsome Therapeutics have? As of today, Axsome Therapeutics has 683 employees.
Who is the CEO of Axsome Therapeutics? Axsome Therapeutics's CEO is Dr. Herriot Tabuteau, M.D..
Is Axsome Therapeutics publicy listed? Yes, Axsome Therapeutics is a public company listed on NAS.
What is the stock symbol of Axsome Therapeutics? Axsome Therapeutics trades under AXSM ticker.
When did Axsome Therapeutics go public? Axsome Therapeutics went public in 2015.
Who are competitors of Axsome Therapeutics? Similar companies to Axsome Therapeutics include e.g. Julphar, Benevolent AI, Galapagos, Pharming.
What is the current market cap of Axsome Therapeutics? Axsome Therapeutics's current market cap is $5.1B
What is the current revenue of Axsome Therapeutics? Axsome Therapeutics's last 12-month revenue is $457M.
What is the current EBITDA of Axsome Therapeutics? Axsome Therapeutics's last 12-month EBITDA is -$219M.
What is the current EV/Revenue multiple of Axsome Therapeutics? Current revenue multiple of Axsome Therapeutics is 10.8x.
What is the current EV/EBITDA multiple of Axsome Therapeutics? Current EBITDA multiple of Axsome Therapeutics is -22.6x.
What is the current revenue growth of Axsome Therapeutics? Axsome Therapeutics revenue growth between 2023 and 2024 was 43%.
Is Axsome Therapeutics profitable? Yes, Axsome Therapeutics is EBITDA-positive (as of the last 12 months).

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