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Apellis Pharmaceuticals Valuation Multiples

Discover revenue and EBITDA valuation multiples for Apellis Pharmaceuticals and similar public comparables like Vivoryon Therapeutics, Pharming, and Galapagos.

Apellis Pharmaceuticals Overview

About Apellis Pharmaceuticals

Apellis Pharmaceuticals Inc is a commercial-stage biopharmaceutical company focused on the discovery, development, and commercialization of novel therapeutic compounds to treat diseases with high unmet needs through the inhibition of the complement system, which is an integral component of the immune system, at the level of C3, the central protein in the complement cascade.


Founded

2009

HQ

United States of America
Employees

710

Website

apellis.com

Financials

LTM Revenue $773M

LTM EBITDA -$119M

EV

$2.6B

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Apellis Pharmaceuticals Financials

Apellis Pharmaceuticals has a last 12-month revenue (LTM) of $773M and a last 12-month EBITDA of -$119M.

In the most recent fiscal year, Apellis Pharmaceuticals achieved revenue of $781M and an EBITDA of -$155M.

Apellis Pharmaceuticals expects next 12-month revenue of  XXX    and NTM EBITDA of  XXX

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Apellis Pharmaceuticals P&L

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue $773M XXX $781M XXX XXX XXX
Gross Profit $649M XXX $664M XXX XXX XXX
Gross Margin 84% XXX 85% XXX XXX XXX
EBITDA -$119M XXX -$155M XXX XXX XXX
EBITDA Margin -15% XXX -20% XXX XXX XXX
EBIT -$157M XXX -$165M XXX XXX XXX
EBIT Margin -20% XXX -21% XXX XXX XXX
Net Profit -$224M XXX -$198M XXX XXX XXX
Net Margin -29% XXX -25% XXX XXX XXX
Net Debt XXX XXX $41.5M XXX XXX XXX

Financial data powered by Morningstar, Inc.

Apellis Pharmaceuticals Stock Performance

As of July 17, 2025, Apellis Pharmaceuticals's stock price is $20.

Apellis Pharmaceuticals has current market cap of $2.5B, and EV of $2.6B.

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Apellis Pharmaceuticals Stock Data

EV Market Cap Price 1D Price 1M Price 3M Price 12M EPS
$2.6B $2.5B XXX XXX XXX XXX $-1.78

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Apellis Pharmaceuticals Valuation Multiples

As of July 17, 2025, Apellis Pharmaceuticals has market cap of $2.5B and EV of $2.6B.

Apellis Pharmaceuticals's trades at 3.3x EV/Revenue multiple, and -16.8x EV/EBITDA.

Equity research analysts estimate Apellis Pharmaceuticals's 2025E EV/Revenue multiple at  XXX and 2025E EV/EBITDA multiple at  XXX

Apellis Pharmaceuticals has a P/E ratio of -11.1x.

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Apellis Pharmaceuticals Financial Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Market cap (current) $2.5B XXX $2.5B XXX XXX XXX
EV (current) $2.6B XXX $2.6B XXX XXX XXX
EV/Revenue 3.4x XXX 3.3x XXX XXX XXX
EV/EBITDA -21.7x XXX -16.8x XXX XXX XXX
EV/EBIT -16.5x XXX -15.7x XXX XXX XXX
EV/Gross Profit 4.0x XXX n/a XXX XXX XXX
P/E -11.1x XXX -12.5x XXX XXX XXX
EV/FCF -37.4x XXX -29.4x XXX XXX XXX

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Apellis Pharmaceuticals Margins & Growth Rates

Apellis Pharmaceuticals's last 12 month revenue growth is 10%

Apellis Pharmaceuticals's revenue per employee in the last FY averaged $1.1M, while opex per employee averaged $1.2M for the same period.

Apellis Pharmaceuticals's rule of 40 is -115% (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Apellis Pharmaceuticals's rule of X is 10% (created by Bessemer, rule of X is another metric relevant for SaaS companies only, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

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Apellis Pharmaceuticals Operational Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue Growth 10% XXX 9% XXX XXX XXX
EBITDA Margin -15% XXX -20% XXX XXX XXX
EBITDA Growth -68% XXX n/a XXX XXX XXX
Rule of 40 -115% XXX -10% XXX XXX XXX
Bessemer Rule of X XXX XXX 10% XXX XXX XXX
Revenue per Employee XXX XXX $1.1M XXX XXX XXX
Opex per Employee XXX XXX $1.2M XXX XXX XXX
S&M Expenses to Revenue XXX XXX n/a XXX XXX XXX
G&A Expenses to Revenue XXX XXX n/a XXX XXX XXX
R&D Expenses to Revenue XXX XXX 42% XXX XXX XXX
Opex to Revenue XXX XXX 106% XXX XXX XXX

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Apellis Pharmaceuticals Public Comps

See public comps and valuation multiples for Drug Development & Therapeutics comps
EV/Revenue EV/EBITDA
2025E 2026E 2027E 2025E 2026E 2027E
Julphar XXX XXX XXX XXX XXX XXX
Benevolent AI XXX XXX XXX XXX XXX XXX
Galapagos XXX XXX XXX XXX XXX XXX
Pharming XXX XXX XXX XXX XXX XXX
Vivoryon Therapeutics XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX

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Apellis Pharmaceuticals M&A and Investment Activity

Apellis Pharmaceuticals acquired  XXX companies to date.

Last acquisition by Apellis Pharmaceuticals was  XXXXXXXX, XXXXX XXXXX XXXXXX . Apellis Pharmaceuticals acquired  XXXXXXXX for  XXX (EV/Revenue multiple of  XXX ).

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Latest Acquisitions by Apellis Pharmaceuticals

Acquired Company EV EV/Revenue EV/EBITDA
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX

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About Apellis Pharmaceuticals

When was Apellis Pharmaceuticals founded? Apellis Pharmaceuticals was founded in 2009.
Where is Apellis Pharmaceuticals headquartered? Apellis Pharmaceuticals is headquartered in United States of America.
How many employees does Apellis Pharmaceuticals have? As of today, Apellis Pharmaceuticals has 710 employees.
Who is the CEO of Apellis Pharmaceuticals? Apellis Pharmaceuticals's CEO is Dr. Cedric Francois, M.D..
Is Apellis Pharmaceuticals publicy listed? Yes, Apellis Pharmaceuticals is a public company listed on NAS.
What is the stock symbol of Apellis Pharmaceuticals? Apellis Pharmaceuticals trades under APLS ticker.
When did Apellis Pharmaceuticals go public? Apellis Pharmaceuticals went public in 2017.
Who are competitors of Apellis Pharmaceuticals? Similar companies to Apellis Pharmaceuticals include e.g. Julphar, Benevolent AI, Galapagos, Pharming.
What is the current market cap of Apellis Pharmaceuticals? Apellis Pharmaceuticals's current market cap is $2.5B
What is the current revenue of Apellis Pharmaceuticals? Apellis Pharmaceuticals's last 12 months revenue is $773M.
What is the current revenue growth of Apellis Pharmaceuticals? Apellis Pharmaceuticals revenue growth (NTM/LTM) is 10%.
What is the current EV/Revenue multiple of Apellis Pharmaceuticals? Current revenue multiple of Apellis Pharmaceuticals is 3.4x.
Is Apellis Pharmaceuticals profitable? Yes, Apellis Pharmaceuticals is EBITDA-positive (as of the last 12 months).
What is the current EBITDA of Apellis Pharmaceuticals? Apellis Pharmaceuticals's last 12 months EBITDA is -$119M.
What is Apellis Pharmaceuticals's EBITDA margin? Apellis Pharmaceuticals's last 12 months EBITDA margin is -15%.
What is the current EV/EBITDA multiple of Apellis Pharmaceuticals? Current EBITDA multiple of Apellis Pharmaceuticals is -21.7x.
What is the current FCF of Apellis Pharmaceuticals? Apellis Pharmaceuticals's last 12 months FCF is -$69.4M.
What is Apellis Pharmaceuticals's FCF margin? Apellis Pharmaceuticals's last 12 months FCF margin is -9%.
What is the current EV/FCF multiple of Apellis Pharmaceuticals? Current FCF multiple of Apellis Pharmaceuticals is -37.4x.

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