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Amylyx Pharmaceuticals Valuation Multiples

Discover revenue and EBITDA valuation multiples for Amylyx Pharmaceuticals and similar public comparables like Vivoryon Therapeutics, Pharming, and Galapagos.

Amylyx Pharmaceuticals Overview

About Amylyx Pharmaceuticals

Amylyx Pharmaceuticals Inc is a clinical-stage pharmaceutical company working on developing a novel therapeutic for amyotrophic lateral sclerosis and other neurodegenerative diseases. It has one operating segment which is the business of researching and developing therapeutics for neurodegenerative disorder and endocrine conditions.


Founded

2014

HQ

United States of America
Employees

123

Website

amylyx.com

Financials

LTM Revenue $51.2M

Last FY EBITDA -$291M

EV

$256M

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Amylyx Pharmaceuticals Financials

Amylyx Pharmaceuticals has a last 12-month revenue (LTM) of $51.2M and a last 12-month EBITDA of n/a.

In the most recent fiscal year, Amylyx Pharmaceuticals achieved revenue of $87.4M and an EBITDA of -$291M.

Amylyx Pharmaceuticals expects next 12-month revenue of  XXX    and NTM EBITDA of  XXX

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Amylyx Pharmaceuticals P&L

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue $51.2M XXX $87.4M XXX XXX XXX
Gross Profit -$21.8M XXX -$37.3M XXX XXX XXX
Gross Margin -43% XXX -43% XXX XXX XXX
EBITDA n/a XXX -$291M XXX XXX XXX
EBITDA Margin n/a XXX -333% XXX XXX XXX
EBIT -$250M XXX -$292M XXX XXX XXX
EBIT Margin -488% XXX -334% XXX XXX XXX
Net Profit -$239M XXX -$302M XXX XXX XXX
Net Margin -466% XXX -345% XXX XXX XXX
Net Debt XXX XXX n/a XXX XXX XXX

Financial data powered by Morningstar, Inc.

Amylyx Pharmaceuticals Stock Performance

As of May 30, 2025, Amylyx Pharmaceuticals's stock price is $5.

Amylyx Pharmaceuticals has current market cap of $459M, and EV of $256M.

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Amylyx Pharmaceuticals Stock Data

EV Market Cap Price 1D Price 1M Price 3M Price 12M EPS
$256M $459M XXX XXX XXX XXX $-3.32

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Amylyx Pharmaceuticals Valuation Multiples

As of May 30, 2025, Amylyx Pharmaceuticals has market cap of $459M and EV of $256M.

Amylyx Pharmaceuticals's trades at 2.9x EV/Revenue multiple, and -0.9x EV/EBITDA.

Equity research analysts estimate Amylyx Pharmaceuticals's 2025E EV/Revenue multiple at  XXX and 2025E EV/EBITDA multiple at  XXX

Amylyx Pharmaceuticals has a P/E ratio of -1.9x.

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Amylyx Pharmaceuticals Financial Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Market cap (current) $459M XXX $459M XXX XXX XXX
EV (current) $256M XXX $256M XXX XXX XXX
EV/Revenue 5.0x XXX 2.9x XXX XXX XXX
EV/EBITDA n/a XXX -0.9x XXX XXX XXX
EV/EBIT -1.0x XXX -0.9x XXX XXX XXX
EV/Gross Profit -11.7x XXX n/a XXX XXX XXX
P/E -1.9x XXX -1.5x XXX XXX XXX
EV/FCF n/a XXX -1.5x XXX XXX XXX

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Amylyx Pharmaceuticals Margins & Growth Rates

Amylyx Pharmaceuticals's last 12 month revenue growth is -100%

Amylyx Pharmaceuticals's revenue per employee in the last FY averaged $0.7M, while opex per employee averaged $2.1M for the same period.

Amylyx Pharmaceuticals's rule of 40 is -89% (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Amylyx Pharmaceuticals's rule of X is unknown (created by Bessemer, rule of X is another metric relevant for SaaS companies only, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

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Amylyx Pharmaceuticals Operational Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue Growth -100% XXX -96% XXX XXX XXX
EBITDA Margin n/a XXX -333% XXX XXX XXX
EBITDA Growth n/a XXX n/a XXX XXX XXX
Rule of 40 -89% XXX -433% XXX XXX XXX
Bessemer Rule of X XXX XXX n/a XXX XXX XXX
Revenue per Employee XXX XXX $0.7M XXX XXX XXX
Opex per Employee XXX XXX $2.1M XXX XXX XXX
S&M Expenses to Revenue XXX XXX n/a XXX XXX XXX
G&A Expenses to Revenue XXX XXX n/a XXX XXX XXX
R&D Expenses to Revenue XXX XXX 161% XXX XXX XXX
Opex to Revenue XXX XXX 291% XXX XXX XXX

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Amylyx Pharmaceuticals Public Comps

See public comps and valuation multiples for Drug Development & Therapeutics comps
EV/Revenue EV/EBITDA
2025E 2026E 2027E 2025E 2026E 2027E
Julphar XXX XXX XXX XXX XXX XXX
Benevolent AI XXX XXX XXX XXX XXX XXX
Galapagos XXX XXX XXX XXX XXX XXX
Pharming XXX XXX XXX XXX XXX XXX
Vivoryon Therapeutics XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX

Valuation data powered by FactSet, Inc.

Amylyx Pharmaceuticals M&A and Investment Activity

Amylyx Pharmaceuticals acquired  XXX companies to date.

Last acquisition by Amylyx Pharmaceuticals was  XXXXXXXX, XXXXX XXXXX XXXXXX . Amylyx Pharmaceuticals acquired  XXXXXXXX for  XXX (EV/Revenue multiple of  XXX ).

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Latest Acquisitions by Amylyx Pharmaceuticals

Acquired Company EV EV/Revenue EV/EBITDA
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX

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About Amylyx Pharmaceuticals

When was Amylyx Pharmaceuticals founded? Amylyx Pharmaceuticals was founded in 2014.
Where is Amylyx Pharmaceuticals headquartered? Amylyx Pharmaceuticals is headquartered in United States of America.
How many employees does Amylyx Pharmaceuticals have? As of today, Amylyx Pharmaceuticals has 123 employees.
Who is the CEO of Amylyx Pharmaceuticals? Amylyx Pharmaceuticals's CEO is Mr. Joshua Cohen.
Is Amylyx Pharmaceuticals publicy listed? Yes, Amylyx Pharmaceuticals is a public company listed on NAS.
What is the stock symbol of Amylyx Pharmaceuticals? Amylyx Pharmaceuticals trades under AMLX ticker.
When did Amylyx Pharmaceuticals go public? Amylyx Pharmaceuticals went public in 2022.
Who are competitors of Amylyx Pharmaceuticals? Similar companies to Amylyx Pharmaceuticals include e.g. Julphar, Benevolent AI, Galapagos, Pharming.
What is the current market cap of Amylyx Pharmaceuticals? Amylyx Pharmaceuticals's current market cap is $459M
What is the current revenue of Amylyx Pharmaceuticals? Amylyx Pharmaceuticals's last 12 months revenue is $51.2M.
What is the current revenue growth of Amylyx Pharmaceuticals? Amylyx Pharmaceuticals revenue growth (NTM/LTM) is -100%.
What is the current EV/Revenue multiple of Amylyx Pharmaceuticals? Current revenue multiple of Amylyx Pharmaceuticals is 5.0x.
Is Amylyx Pharmaceuticals profitable? Yes, Amylyx Pharmaceuticals is EBITDA-positive (as of the last 12 months).

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