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Alto Neuroscience Valuation Multiples

Discover revenue and EBITDA valuation multiples for Alto Neuroscience and similar public comparables like Vivoryon Therapeutics, Pharming, and Benevolent AI.

Alto Neuroscience Overview

About Alto Neuroscience

Alto Neuroscience Inc is a clinical-stage biopharmaceutical company with a mission to redefine psychiatry by leveraging individuals’ neurobiology to develop personalized and effective treatment options. The company currently consists of different clinical-stage assets such as ALTO-100, ALTO-202, ALTO-101, and ALTO-300 among others initially targeting depressive disorders and schizophrenia populations as identified by independent brain-based biomarkers.


Founded

2019

HQ

United States of America
Employees

76

Financials

Last FY Revenue n/a

LTM EBITDA -$73.4M

EV

-$64.5M

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Alto Neuroscience Financials

Alto Neuroscience has a last 12-month revenue (LTM) of n/a and a last 12-month EBITDA of -$73.4M.

In the most recent fiscal year, Alto Neuroscience achieved revenue of n/a and an EBITDA of -$59.6M.

Alto Neuroscience expects next 12-month revenue of  XXX    and NTM EBITDA of  XXX

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Alto Neuroscience P&L

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue n/a XXX n/a XXX XXX XXX
Gross Profit n/a XXX n/a XXX XXX XXX
Gross Margin n/a XXX n/a XXX XXX XXX
EBITDA -$73.4M XXX -$59.6M XXX XXX XXX
EBITDA Margin n/a XXX n/a XXX XXX XXX
EBIT -$70.7M XXX -$68.6M XXX XXX XXX
EBIT Margin n/a XXX n/a XXX XXX XXX
Net Profit -$64.7M XXX -$61.4M XXX XXX XXX
Net Margin n/a XXX n/a XXX XXX XXX
Net Debt XXX XXX n/a XXX XXX XXX

Financial data powered by Morningstar, Inc.

Alto Neuroscience Stock Performance

As of May 30, 2025, Alto Neuroscience's stock price is $3.

Alto Neuroscience has current market cap of $69.8M, and EV of -$64.5M.

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Alto Neuroscience Stock Data

EV Market Cap Price 1D Price 1M Price 3M Price 12M EPS
-$64.5M $69.8M XXX XXX XXX XXX $-2.49

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Alto Neuroscience Valuation Multiples

As of May 30, 2025, Alto Neuroscience has market cap of $69.8M and EV of -$64.5M.

Alto Neuroscience's trades at n/a EV/Revenue multiple, and 1.1x EV/EBITDA.

Equity research analysts estimate Alto Neuroscience's 2025E EV/Revenue multiple at  XXX and 2025E EV/EBITDA multiple at  XXX

Alto Neuroscience has a P/E ratio of -1.1x.

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Alto Neuroscience Financial Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Market cap (current) $69.8M XXX $69.8M XXX XXX XXX
EV (current) -$64.5M XXX -$64.5M XXX XXX XXX
EV/Revenue n/a XXX n/a XXX XXX XXX
EV/EBITDA 0.9x XXX 1.1x XXX XXX XXX
EV/EBIT 0.9x XXX 0.9x XXX XXX XXX
EV/Gross Profit n/a XXX n/a XXX XXX XXX
P/E -1.1x XXX -1.1x XXX XXX XXX
EV/FCF 1.3x XXX 1.3x XXX XXX XXX

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Alto Neuroscience Margins & Growth Rates

Alto Neuroscience's revenue per employee in the last FY averaged n/a, while opex per employee averaged $0.9M for the same period.

Alto Neuroscience's rule of 40 is unknown (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Alto Neuroscience's rule of X is n/a (created by Bessemer, rule of X is another metric relevant for SaaS companies only, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

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Alto Neuroscience Operational Valuation Multiples

LTM NTM Last FY FY 2025 FY 2026 FY 2027
Revenue Growth n/a XXX n/a XXX XXX XXX
EBITDA Margin n/a XXX n/a XXX XXX XXX
EBITDA Growth 26% XXX 53% XXX XXX XXX
Rule of 40 n/a XXX n/a XXX XXX XXX
Bessemer Rule of X XXX XXX n/a XXX XXX XXX
Revenue per Employee XXX XXX n/a XXX XXX XXX
Opex per Employee XXX XXX $0.9M XXX XXX XXX
S&M Expenses to Revenue XXX XXX n/a XXX XXX XXX
G&A Expenses to Revenue XXX XXX n/a XXX XXX XXX
R&D Expenses to Revenue XXX XXX n/a XXX XXX XXX
Opex to Revenue XXX XXX n/a XXX XXX XXX

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Alto Neuroscience Public Comps

See public comps and valuation multiples for Drug Development & Therapeutics comps
EV/Revenue EV/EBITDA
2025E 2026E 2027E 2025E 2026E 2027E
Julphar XXX XXX XXX XXX XXX XXX
Benevolent AI XXX XXX XXX XXX XXX XXX
Galapagos XXX XXX XXX XXX XXX XXX
Pharming XXX XXX XXX XXX XXX XXX
Vivoryon Therapeutics XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX
XXXXXXXX XXX XXX XXX XXX XXX XXX

Valuation data powered by FactSet, Inc.

Alto Neuroscience M&A and Investment Activity

Alto Neuroscience acquired  XXX companies to date.

Last acquisition by Alto Neuroscience was  XXXXXXXX, XXXXX XXXXX XXXXXX . Alto Neuroscience acquired  XXXXXXXX for  XXX (EV/Revenue multiple of  XXX ).

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Latest Acquisitions by Alto Neuroscience

Acquired Company EV EV/Revenue EV/EBITDA
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX
XXXXXXXXX XXX XXX XXX

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About Alto Neuroscience

When was Alto Neuroscience founded? Alto Neuroscience was founded in 2019.
Where is Alto Neuroscience headquartered? Alto Neuroscience is headquartered in United States of America.
How many employees does Alto Neuroscience have? As of today, Alto Neuroscience has 76 employees.
Who is the CEO of Alto Neuroscience? Alto Neuroscience's CEO is Dr. Amit Etkin, M.D.,PhD.
Is Alto Neuroscience publicy listed? Yes, Alto Neuroscience is a public company listed on NYS.
What is the stock symbol of Alto Neuroscience? Alto Neuroscience trades under ANRO ticker.
When did Alto Neuroscience go public? Alto Neuroscience went public in 2024.
Who are competitors of Alto Neuroscience? Similar companies to Alto Neuroscience include e.g. Julphar, Benevolent AI, Galapagos, Pharming.
What is the current market cap of Alto Neuroscience? Alto Neuroscience's current market cap is $69.8M
Is Alto Neuroscience profitable? Yes, Alto Neuroscience is EBITDA-positive (as of the last 12 months).
What is the current EBITDA of Alto Neuroscience? Alto Neuroscience's last 12 months EBITDA is -$73.4M.
What is the current EV/EBITDA multiple of Alto Neuroscience? Current EBITDA multiple of Alto Neuroscience is 0.9x.
What is the current FCF of Alto Neuroscience? Alto Neuroscience's last 12 months FCF is -$50.3M.
What is the current EV/FCF multiple of Alto Neuroscience? Current FCF multiple of Alto Neuroscience is 1.3x.

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