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Agios Pharmaceuticals Valuation Multiples

Discover revenue and EBITDA valuation multiples for Agios Pharmaceuticals and similar public comparables like Mesoblast, Ocular Therapeutix, Cheezheng Tibetan Medicine, Zymeworks and more.

Agios Pharmaceuticals Overview

About Agios Pharmaceuticals

Agios Pharmaceuticals Inc is a biopharmaceutical company focused on the field of cellular metabolism to create differentiated medicines for rare diseases, with a focus on classical hematology. The company's primary focus is to develop potentially transformative small-molecule medicines. Its product candidate, Pyrukynd (mitapivat), is an activator of both wild-type and mutant pyruvate kinase enzymes, developed for the treatment of hemolytic anemias. The other drug candidates in its pipeline include Tebapivat (PK activator), being developed as a potential treatment for MDS-associated anemia and sickle cell disease, AG-181 (PAH stabilizer), AG-236 and others.


Founded

2007

HQ

United States

Employees

540

Website

agios.com

Financials (LTM)

Revenue: $65M
EBITDA: ($461M)

EV

$1B

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Agios Pharmaceuticals Financials

Agios Pharmaceuticals reported last 12-month revenue of $65M and negative EBITDA of ($461M).

In the same LTM period, Agios Pharmaceuticals generated $58M in gross profit, ($461M) in EBITDA losses, and had net loss of ($407M).

Revenue (LTM)


Agios Pharmaceuticals P&L

In the most recent fiscal year, Agios Pharmaceuticals reported revenue of $54M and EBITDA of ($467M).

Agios Pharmaceuticals expects next 12-month revenue of XXX and NTM EBITDA of XXX

See Agios Pharmaceuticals forward-looking valuation multiples
LTMNTMLast FYFY 2026FY 2027FY 2028
Revenue$65MXXX$54MXXXXXXXXX
Gross Profit$58MXXX$48MXXXXXXXXX
Gross Margin89%XXX88%XXXXXXXXX
EBITDA($461M)XXX($467M)XXXXXXXXX
EBITDA Margin(714%)XXX(864%)XXXXXXXXX
EBIT Margin(718%)XXX(874%)XXXXXXXXX
Net Profit($407M)XXX($413M)XXXXXXXXX
Net Margin(631%)XXX(764%)XXXXXXXXX

Financial data powered by Morningstar, Inc.

Agios Pharmaceuticals Stock Performance

Agios Pharmaceuticals has current market cap of $2B, and enterprise value of $1B.

Market Cap Evolution


Agios Pharmaceuticals' stock price is $32.92.

See Agios Pharmaceuticals trading valuation data
EVMarket CapPrice 1DPrice 1MPrice 3MPrice 12MEPS
$1B$2B0.0%XXXXXXXXX$-7.04

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Agios Pharmaceuticals Valuation Multiples

Agios Pharmaceuticals trades at 17.3x EV/Revenue multiple, and (2.4x) EV/EBITDA.

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EV / Revenue (LTM)


Agios Pharmaceuticals Financial Valuation Multiples

As of April 12, 2026, Agios Pharmaceuticals has market cap of $2B and EV of $1B.

Equity research analysts estimate Agios Pharmaceuticals' 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX

Agios Pharmaceuticals has a P/E ratio of (4.7x).

LTMNTMLast FYFY 2026FY 2027FY 2028
Market cap (current)$2BXXX$2BXXXXXXXXX
EV (current)$1BXXX$1BXXXXXXXXX
EV/Revenue17.3xXXX20.6xXXXXXXXXX
EV/EBITDA(2.4x)XXX(2.4x)XXXXXXXXX
EV/EBIT(2.4x)XXX(2.4x)XXXXXXXXX
EV/Gross Profit19.3xXXX23.4xXXXXXXXXX
P/E(4.7x)XXX(4.7x)XXXXXXXXX
EV/FCF(5.8x)XXX(3.7x)XXXXXXXXX

Valuation data powered by FactSet, Inc. and Morningstar, Inc.

Verified Agios Pharmaceuticals Valuation Multiples

Access all public comps and forward-looking valuation multiples like EV/Revenue in 2027, based on consensus analyst estimates. Powered by FactSet and Morningstar.

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Agios Pharmaceuticals Margins & Growth Rates

Agios Pharmaceuticals' revenue in the last 12 month grew by 107%.

Agios Pharmaceuticals' revenue per employee in the last FY averaged $0.1M, while opex per employee averaged $1.0M for the same period.

Agios Pharmaceuticals' rule of 40 is (413%) (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

Agios Pharmaceuticals' rule of X is (307%) (created by Bessemer, rule of X is another metric to measure SaaS companies, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

See operational valuation multiples for Agios Pharmaceuticals and other 15K+ public comps

Agios Pharmaceuticals Operational Valuation Multiples

LTMNTMLast FYFY 2026FY 2027FY 2028
Revenue Growth107%XXX70%XXXXXXXXX
EBITDA Margin(714%)XXX(864%)XXXXXXXXX
EBITDA Growth(9%)XXX(5%)XXXXXXXXX
Rule of 40—XXX(413%)XXXXXXXXX
Bessemer Rule of X—XXX(307%)XXXXXXXXX
Revenue per Employee—XXX$0.1MXXXXXXXXX
Opex per Employee—XXX$1.0MXXXXXXXXX
G&A Expenses to Revenue293%XXX334%XXXXXXXXX
R&D Expenses to Revenue511%XXX629%XXXXXXXXX
Opex to Revenue—XXX962%XXXXXXXXX

Valuation data powered by FactSet, Inc. and Morningstar, Inc.

Valuation Multiples Across 230+ Verticals

Agios Pharmaceuticals Public Comps

See public comps and valuation multiples for other Biopharmaceuticals comps.

EV/RevenueEV/EBITDA
LTM2026E2027ELTM2026E2027E
MesoblastXXXXXXXXXXXXXXXXXX
Ocular TherapeutixXXXXXXXXXXXXXXXXXX
Cheezheng Tibetan MedicineXXXXXXXXXXXXXXXXXX
ZymeworksXXXXXXXXXXXXXXXXXX
Tyra BiosciencesXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX

Valuation data powered by FactSet, Inc.

Agios Pharmaceuticals M&A Activity

Agios Pharmaceuticals acquired XXX companies to date.

Last acquisition by Agios Pharmaceuticals was on XXXXXXXX, XXXXX. Agios Pharmaceuticals acquired XXXXXXXX for XXX (EV/Revenue multiple of XXX).

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Latest Acquisitions by Agios Pharmaceuticals

Acquired CompanyValuationEV/RevenueEV/EBITDA
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX

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Agios Pharmaceuticals Investment Activity

Agios Pharmaceuticals invested in XXX companies to date.

Agios Pharmaceuticals made its latest investment on XXXXXXXX, XXXXX. Agios Pharmaceuticals invested in XXXXXXXX for XXX (EV/Revenue multiple of XXX).

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Latest Investments by Agios Pharmaceuticals

CompanyValuationEV/RevenueEV/EBITDA
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX

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About Agios Pharmaceuticals

When was Agios Pharmaceuticals founded?Agios Pharmaceuticals was founded in 2007.
Where is Agios Pharmaceuticals headquartered?Agios Pharmaceuticals is headquartered in United States.
How many employees does Agios Pharmaceuticals have?As of today, Agios Pharmaceuticals has over 540 employees.
Who is the CEO of Agios Pharmaceuticals?Agios Pharmaceuticals' CEO is Brian Goff.
Is Agios Pharmaceuticals publicly listed?Yes, Agios Pharmaceuticals is a public company listed on Nasdaq.
What is the stock symbol of Agios Pharmaceuticals?Agios Pharmaceuticals trades under AGIO ticker.
When did Agios Pharmaceuticals go public?Agios Pharmaceuticals went public in 2013.
Who are competitors of Agios Pharmaceuticals?Agios Pharmaceuticals main competitors are Mesoblast, Ocular Therapeutix, Cheezheng Tibetan Medicine, Zymeworks.
What is the current market cap of Agios Pharmaceuticals?Agios Pharmaceuticals' current market cap is $2B.
What is the current revenue of Agios Pharmaceuticals?Agios Pharmaceuticals' last 12 months revenue is $65M.
What is the current revenue growth of Agios Pharmaceuticals?Agios Pharmaceuticals revenue growth (NTM/LTM) is 107%.
What is the current EV/Revenue multiple of Agios Pharmaceuticals?Current revenue multiple of Agios Pharmaceuticals is 17.3x.
Is Agios Pharmaceuticals profitable?No, Agios Pharmaceuticals is not profitable.
What is the current EBITDA of Agios Pharmaceuticals?Agios Pharmaceuticals has negative EBITDA and is not profitable.
What is Agios Pharmaceuticals' EBITDA margin?Agios Pharmaceuticals' last 12 months EBITDA margin is (714%).
What is the current EV/EBITDA multiple of Agios Pharmaceuticals?Current EBITDA multiple of Agios Pharmaceuticals is (2.4x).
What is the current FCF of Agios Pharmaceuticals?Agios Pharmaceuticals' last 12 months FCF is ($193M).
What is Agios Pharmaceuticals' FCF margin?Agios Pharmaceuticals' last 12 months FCF margin is (299%).
What is the current EV/FCF multiple of Agios Pharmaceuticals?Current FCF multiple of Agios Pharmaceuticals is (5.8x).

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