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AC Immune Valuation Multiples
Discover revenue and EBITDA valuation multiples for AC Immune and similar public comparables like Fennec Pharmaceuticals, Santhera Pharma, Transgene, Heartseed and more.
AC Immune Overview
About AC Immune
AC Immune SA is a clinical-stage biopharmaceutical company that focuses on neurodegenerative diseases. The company uses its proprietary technology platforms to discover, design, and develop novel proprietary small molecules, antibodies, and vaccines for the prevention, diagnosis, and treatment of neurodegenerative diseases associated with protein misfolding. The Company has one segment. The Company currently focuses mostly of its resources on discovering and developing therapeutic and diagnostic products targeting misfolded proteins. The company's pipeline consists of ACI-24.060, Crenezumab, ACI-35.030, Semorinemab, ACI-7104.056, and others.
Founded
2003
HQ

Employees
161
Website
Sectors
Financials (LTM)
EV
$153M
AC Immune Financials
AC Immune reported last 12-month revenue of $13M and negative EBITDA of ($84M).
In the same LTM period, AC Immune generated $13M in gross profit, ($84M) in EBITDA losses, and had net loss of ($76M).
Revenue (LTM)
AC Immune P&L
In the most recent fiscal year, AC Immune reported revenue of $5M and EBITDA of ($85M).
AC Immune expects next 12-month revenue of XXX and NTM EBITDA of XXX
| LTM | NTM | Last FY | FY 2026 | FY 2027 | FY 2028 | |
|---|---|---|---|---|---|---|
| Revenue | $13M | XXX | $5M | XXX | XXX | XXX |
| Gross Profit | $13M | XXX | — | XXX | XXX | XXX |
| Gross Margin | 100% | XXX | — | XXX | XXX | XXX |
| EBITDA | ($84M) | XXX | ($85M) | XXX | XXX | XXX |
| EBITDA Margin | (660%) | XXX | (1808%) | XXX | XXX | XXX |
| EBIT Margin | (593%) | XXX | (1837%) | XXX | XXX | XXX |
| Net Profit | ($76M) | XXX | ($88M) | XXX | XXX | XXX |
| Net Margin | (597%) | XXX | (1872%) | XXX | XXX | XXX |
Financial data powered by Morningstar, Inc.
AC Immune Stock Performance
AC Immune has current market cap of $286M, and enterprise value of $153M.
Market Cap Evolution
AC Immune's stock price is $2.84.
| EV | Market Cap | Price 1D | Price 1M | Price 3M | Price 12M | EPS |
|---|---|---|---|---|---|---|
| $153M | $286M | 0.0% | XXX | XXX | XXX | $-0.87 |
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Start Free TrialAC Immune Valuation Multiples
AC Immune trades at 12.0x EV/Revenue multiple, and (1.8x) EV/EBITDA.
EV / Revenue (LTM)
AC Immune Financial Valuation Multiples
As of April 7, 2026, AC Immune has market cap of $286M and EV of $153M.
Equity research analysts estimate AC Immune's 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX
AC Immune has a P/E ratio of (3.7x).
| LTM | NTM | Last FY | FY 2026 | FY 2027 | FY 2028 | |
|---|---|---|---|---|---|---|
| Market cap (current) | $286M | XXX | $286M | XXX | XXX | XXX |
| EV (current) | $153M | XXX | $153M | XXX | XXX | XXX |
| EV/Revenue | 12.0x | XXX | 32.6x | XXX | XXX | XXX |
| EV/EBITDA | (1.8x) | XXX | (1.8x) | XXX | XXX | XXX |
| EV/EBIT | (2.0x) | XXX | (1.8x) | XXX | XXX | XXX |
| EV/Gross Profit | 12.0x | XXX | — | XXX | XXX | XXX |
| P/E | (3.7x) | XXX | (3.3x) | XXX | XXX | XXX |
| EV/FCF | — | XXX | (1.7x) | XXX | XXX | XXX |
Valuation data powered by FactSet, Inc. and Morningstar, Inc.
Verified AC Immune Valuation Multiples
Access all public comps and forward-looking valuation multiples like EV/Revenue in 2027, based on consensus analyst estimates. Powered by FactSet and Morningstar.


AC Immune Margins & Growth Rates
AC Immune's revenue in the last 12 month grew by 444%.
AC Immune's revenue per employee in the last FY averaged $0.0M, while opex per employee averaged $0.6M for the same period.
AC Immune's rule of 40 is 477% (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).
AC Immune's rule of X is 1512% (created by Bessemer, rule of X is another metric to measure SaaS companies, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).
AC Immune Operational Valuation Multiples
| LTM | NTM | Last FY | FY 2026 | FY 2027 | FY 2028 | |
|---|---|---|---|---|---|---|
| Revenue Growth | 444% | XXX | 653% | XXX | XXX | XXX |
| EBITDA Margin | (660%) | XXX | (1808%) | XXX | XXX | XXX |
| EBITDA Growth | (39%) | XXX | (11%) | XXX | XXX | XXX |
| Rule of 40 | — | XXX | 477% | XXX | XXX | XXX |
| Bessemer Rule of X | — | XXX | 1512% | XXX | XXX | XXX |
| Revenue per Employee | — | XXX | $0.0M | XXX | XXX | XXX |
| Opex per Employee | — | XXX | $0.6M | XXX | XXX | XXX |
| G&A Expenses to Revenue | — | XXX | 311% | XXX | XXX | XXX |
| R&D Expenses to Revenue | 531% | XXX | 1506% | XXX | XXX | XXX |
| Opex to Revenue | — | XXX | 1933% | XXX | XXX | XXX |
Valuation data powered by FactSet, Inc. and Morningstar, Inc.
AC Immune Public Comps
See public comps and valuation multiples for other Biopharmaceuticals comps.
| EV/Revenue | EV/EBITDA | |||||
|---|---|---|---|---|---|---|
| LTM | 2026E | 2027E | LTM | 2026E | 2027E | |
| Fennec Pharmaceuticals | XXX | XXX | XXX | XXX | XXX | XXX |
| Santhera Pharma | XXX | XXX | XXX | XXX | XXX | XXX |
| Transgene | XXX | XXX | XXX | XXX | XXX | XXX |
| Heartseed | XXX | XXX | XXX | XXX | XXX | XXX |
| Biofarm | XXX | XXX | XXX | XXX | XXX | XXX |
| XXXXXXXX | XXX | XXX | XXX | XXX | XXX | XXX |
| XXXXXXXX | XXX | XXX | XXX | XXX | XXX | XXX |
Valuation data powered by FactSet, Inc.
AC Immune M&A Activity
AC Immune acquired XXX companies to date.
Last acquisition by AC Immune was on XXXXXXXX, XXXXX. AC Immune acquired XXXXXXXX for XXX (EV/Revenue multiple of XXX).
Latest Acquisitions by AC Immune
| Acquired Company | Valuation | EV/Revenue | EV/EBITDA |
|---|---|---|---|
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
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Start Free TrialAC Immune Investment Activity
AC Immune invested in XXX companies to date.
AC Immune made its latest investment on XXXXXXXX, XXXXX. AC Immune invested in XXXXXXXX for XXX (EV/Revenue multiple of XXX).
Latest Investments by AC Immune
| Company | Valuation | EV/Revenue | EV/EBITDA |
|---|---|---|---|
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
| XXXXXXXXXXXX | XXX | XXX | XXX |
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Start Free TrialAbout AC Immune
| When was AC Immune founded? | AC Immune was founded in 2003. |
| Where is AC Immune headquartered? | AC Immune is headquartered in Switzerland. |
| How many employees does AC Immune have? | As of today, AC Immune has over 161 employees. |
| Who is the CEO of AC Immune? | AC Immune's CEO is Professor Dr. Andrea Pfeifer. |
| Is AC Immune publicly listed? | Yes, AC Immune is a public company listed on Nasdaq. |
| What is the stock symbol of AC Immune? | AC Immune trades under ACIU ticker. |
| When did AC Immune go public? | AC Immune went public in 2016. |
| Who are competitors of AC Immune? | AC Immune main competitors are Fennec Pharmaceuticals, Santhera Pharma, Transgene, Heartseed. |
| What is the current market cap of AC Immune? | AC Immune's current market cap is $286M. |
| What is the current revenue of AC Immune? | AC Immune's last 12 months revenue is $13M. |
| What is the current revenue growth of AC Immune? | AC Immune revenue growth (NTM/LTM) is 444%. |
| What is the current EV/Revenue multiple of AC Immune? | Current revenue multiple of AC Immune is 12.0x. |
| Is AC Immune profitable? | No, AC Immune is not profitable. |
| What is the current EBITDA of AC Immune? | AC Immune has negative EBITDA and is not profitable. |
| What is AC Immune's EBITDA margin? | AC Immune's last 12 months EBITDA margin is (660%). |
| What is the current EV/EBITDA multiple of AC Immune? | Current EBITDA multiple of AC Immune is (1.8x). |
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