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AC Immune Valuation Multiples

Discover revenue and EBITDA valuation multiples for AC Immune and similar public comparables like Fennec Pharmaceuticals, Santhera Pharma, Transgene, Heartseed and more.

AC Immune Overview

About AC Immune

AC Immune SA is a clinical-stage biopharmaceutical company that focuses on neurodegenerative diseases. The company uses its proprietary technology platforms to discover, design, and develop novel proprietary small molecules, antibodies, and vaccines for the prevention, diagnosis, and treatment of neurodegenerative diseases associated with protein misfolding. The Company has one segment. The Company currently focuses mostly of its resources on discovering and developing therapeutic and diagnostic products targeting misfolded proteins. The company's pipeline consists of ACI-24.060, Crenezumab, ACI-35.030, Semorinemab, ACI-7104.056, and others.


Founded

2003

HQ

Switzerland

Employees

161

Financials (LTM)

Revenue: $13M
EBITDA: ($84M)

EV

$153M

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AC Immune Financials

AC Immune reported last 12-month revenue of $13M and negative EBITDA of ($84M).

In the same LTM period, AC Immune generated $13M in gross profit, ($84M) in EBITDA losses, and had net loss of ($76M).

Revenue (LTM)


AC Immune P&L

In the most recent fiscal year, AC Immune reported revenue of $5M and EBITDA of ($85M).

AC Immune expects next 12-month revenue of XXX and NTM EBITDA of XXX

See AC Immune forward-looking valuation multiples
LTMNTMLast FYFY 2026FY 2027FY 2028
Revenue$13MXXX$5MXXXXXXXXX
Gross Profit$13MXXX—XXXXXXXXX
Gross Margin100%XXX—XXXXXXXXX
EBITDA($84M)XXX($85M)XXXXXXXXX
EBITDA Margin(660%)XXX(1808%)XXXXXXXXX
EBIT Margin(593%)XXX(1837%)XXXXXXXXX
Net Profit($76M)XXX($88M)XXXXXXXXX
Net Margin(597%)XXX(1872%)XXXXXXXXX

Financial data powered by Morningstar, Inc.

AC Immune Stock Performance

AC Immune has current market cap of $286M, and enterprise value of $153M.

Market Cap Evolution


AC Immune's stock price is $2.84.

See AC Immune trading valuation data
EVMarket CapPrice 1DPrice 1MPrice 3MPrice 12MEPS
$153M$286M0.0%XXXXXXXXX$-0.87

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AC Immune Valuation Multiples

AC Immune trades at 12.0x EV/Revenue multiple, and (1.8x) EV/EBITDA.

See valuation multiples for AC Immune and 15K+ public comps

EV / Revenue (LTM)


AC Immune Financial Valuation Multiples

As of April 7, 2026, AC Immune has market cap of $286M and EV of $153M.

Equity research analysts estimate AC Immune's 2025E EV/Revenue multiple at XXX and 2025E EV/EBITDA multiple at XXX

AC Immune has a P/E ratio of (3.7x).

LTMNTMLast FYFY 2026FY 2027FY 2028
Market cap (current)$286MXXX$286MXXXXXXXXX
EV (current)$153MXXX$153MXXXXXXXXX
EV/Revenue12.0xXXX32.6xXXXXXXXXX
EV/EBITDA(1.8x)XXX(1.8x)XXXXXXXXX
EV/EBIT(2.0x)XXX(1.8x)XXXXXXXXX
EV/Gross Profit12.0xXXX—XXXXXXXXX
P/E(3.7x)XXX(3.3x)XXXXXXXXX
EV/FCF—XXX(1.7x)XXXXXXXXX

Valuation data powered by FactSet, Inc. and Morningstar, Inc.

Verified AC Immune Valuation Multiples

Access all public comps and forward-looking valuation multiples like EV/Revenue in 2027, based on consensus analyst estimates. Powered by FactSet and Morningstar.

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AC Immune Margins & Growth Rates

AC Immune's revenue in the last 12 month grew by 444%.

AC Immune's revenue per employee in the last FY averaged $0.0M, while opex per employee averaged $0.6M for the same period.

AC Immune's rule of 40 is 477% (metric relevant for SaaS companies only, counted as combined revenue growth rate and EBITDA margin).

AC Immune's rule of X is 1512% (created by Bessemer, rule of X is another metric to measure SaaS companies, ~1.5x stronger vs. the traditional Rule of 40, counted as revenue growth rate multiplied by 2.5 plus EBITDA margin).

See operational valuation multiples for AC Immune and other 15K+ public comps

AC Immune Operational Valuation Multiples

LTMNTMLast FYFY 2026FY 2027FY 2028
Revenue Growth444%XXX653%XXXXXXXXX
EBITDA Margin(660%)XXX(1808%)XXXXXXXXX
EBITDA Growth(39%)XXX(11%)XXXXXXXXX
Rule of 40—XXX477%XXXXXXXXX
Bessemer Rule of X—XXX1512%XXXXXXXXX
Revenue per Employee—XXX$0.0MXXXXXXXXX
Opex per Employee—XXX$0.6MXXXXXXXXX
G&A Expenses to Revenue—XXX311%XXXXXXXXX
R&D Expenses to Revenue531%XXX1506%XXXXXXXXX
Opex to Revenue—XXX1933%XXXXXXXXX

Valuation data powered by FactSet, Inc. and Morningstar, Inc.

Valuation Multiples Across 230+ Verticals

AC Immune Public Comps

See public comps and valuation multiples for other Biopharmaceuticals comps.

EV/RevenueEV/EBITDA
LTM2026E2027ELTM2026E2027E
Fennec PharmaceuticalsXXXXXXXXXXXXXXXXXX
Santhera PharmaXXXXXXXXXXXXXXXXXX
TransgeneXXXXXXXXXXXXXXXXXX
HeartseedXXXXXXXXXXXXXXXXXX
BiofarmXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX

Valuation data powered by FactSet, Inc.

AC Immune M&A Activity

AC Immune acquired XXX companies to date.

Last acquisition by AC Immune was on XXXXXXXX, XXXXX. AC Immune acquired XXXXXXXX for XXX (EV/Revenue multiple of XXX).

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Latest Acquisitions by AC Immune

Acquired CompanyValuationEV/RevenueEV/EBITDA
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX

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AC Immune Investment Activity

AC Immune invested in XXX companies to date.

AC Immune made its latest investment on XXXXXXXX, XXXXX. AC Immune invested in XXXXXXXX for XXX (EV/Revenue multiple of XXX).

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Latest Investments by AC Immune

CompanyValuationEV/RevenueEV/EBITDA
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX
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About AC Immune

When was AC Immune founded?AC Immune was founded in 2003.
Where is AC Immune headquartered?AC Immune is headquartered in Switzerland.
How many employees does AC Immune have?As of today, AC Immune has over 161 employees.
Who is the CEO of AC Immune?AC Immune's CEO is Professor Dr. Andrea Pfeifer.
Is AC Immune publicly listed?Yes, AC Immune is a public company listed on Nasdaq.
What is the stock symbol of AC Immune?AC Immune trades under ACIU ticker.
When did AC Immune go public?AC Immune went public in 2016.
Who are competitors of AC Immune?AC Immune main competitors are Fennec Pharmaceuticals, Santhera Pharma, Transgene, Heartseed.
What is the current market cap of AC Immune?AC Immune's current market cap is $286M.
What is the current revenue of AC Immune?AC Immune's last 12 months revenue is $13M.
What is the current revenue growth of AC Immune?AC Immune revenue growth (NTM/LTM) is 444%.
What is the current EV/Revenue multiple of AC Immune?Current revenue multiple of AC Immune is 12.0x.
Is AC Immune profitable?No, AC Immune is not profitable.
What is the current EBITDA of AC Immune?AC Immune has negative EBITDA and is not profitable.
What is AC Immune's EBITDA margin?AC Immune's last 12 months EBITDA margin is (660%).
What is the current EV/EBITDA multiple of AC Immune?Current EBITDA multiple of AC Immune is (1.8x).

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