T-Therapeutics Funding, Investors & Competitors

T-Therapeutics has raised $226M across 3 funding rounds, most recently a $133M Series B in November 2026.

Last T-Therapeutics funding round

$133M

Series B · Nov 2026

Cumulative funding T-Therapeutics raised

$226M

across 3 funding rounds

Key investors in T-Therapeutics

  • F-Prime
  • Sofinnova Partners
  • Sanofi Ventures
  • Cambridge Innovation Capital
  • Digitalis Ventures
  • Tencent
  • Business Growth Fund
  • Johnson & Johnson Innovation

T-Therapeutics Overview

About T-Therapeutics

T-Therapeutics is a Cambridge, UK-based biopharmaceutical company engineering T-cell receptors for cancer immunotherapies. The firm uses mouse genome editing, single-cell genomics, machine learning, and structural biology to identify TCRs targeting tumor antigens. T-Therapeutics advances pipeline candidates into clinical trials, partnering with AstraZeneca for manufacturing and development.


Founded

2022

HQ

United KingdomCambridge

Status

Privately held

Customer focus

B2B

Revenue model

Product sales

T-Therapeutics Funding History

T-Therapeutics has raised a total of $226M across 3 funding rounds.

T-Therapeutics' first fundraising round was a $61M Series A in November 2023. The most recent completed round was a $133M Series B in November 2026.

T-Therapeutics funding rounds

T-Therapeutics funding rounds
DateStageInvestorsRaisedDeal Summary
Nov 2026Series BAdvent Life Sciences (lead); British Business Bank (lead); Digitalis Ventures; M Ventures; Sofinnova Partners; Tencent; F-Prime; Eli Lilly and Company; Cambridge Innovation Capital; Samsara BioCapital; Sanofi Ventures; Johnson & Johnson Innovation$133MT-Therapeutics, a Cambridge, UK-based developer of T cell receptor bispecific therapies, announced on 5 November 2026 the closing of an oversubscribed USD 133 million Series B financing. The round was co-led by Advent Life Sciences and the British Business Bank. New investors included Johnson and Johnson Innovation (JJDC), Samsara BioCapital, M Ventures and Eli Lilly and Company, while existing shareholders including Sofinnova Partners, F-Prime, Digitalis Ventures, Cambridge Innovation Capital, Sanofi Ventures, Tencent and BGF also took part. Representatives of Advent Life Sciences, the British Business Bank, JJDC and Samsara BioCapital will join the board as non-executive directors. The proceeds will fund entry into the clinic and clinical proof-of-concept data for two lead TCR-CD3 bispecific programmes in oncology and autoimmune disease. The financing follows a Series A of USD 59 million in 2023, which was extended by USD 32 million in November 2025. T-Therapeutics is a University of Cambridge spinout founded in 2022 that builds its candidates on its proprietary OpTiMus platform, which generates fully human TCRs against intracellular targets.
Nov 2025Series ADigitalis Ventures; Cambridge Enterprise Ventures; Sofinnova Partners; Tencent; F-Prime; Business Growth Fund; Cambridge Innovation Capital; Sanofi Ventures$32MT-Therapeutics is a Cambridge, UK-based biotechnology company developing next-generation soluble T cell receptor (TCR) therapeutics, including TCR-CD3 bispecific candidates targeting intracellular antigens for oncology and autoimmune diseases. Its OpTiMus platform generates a broad repertoire of fully human TCRs paired with engineered CD3 T cell engagers for potency, safety, and pharmacokinetics to create bispecific drug candidates. The lead oncology asset targets a pan-tumor driver across solid tumor types, while the lead immunology program focuses on pan-autoimmune bispecifics for selective depletion of pathogenic immune cells, enabling precision immune reset and exploring T cell subset depletion. On November 13, 2025, T-Therapeutics announced an extension of its Series A financing with a $32 million new equity injection, bringing the total Series A to $91 million following an initial $59 million raise. New investors Tencent and BGF (Business Growth Fund) joined existing backers including Sofinnova Partners, F-Prime Capital, Digitalis Ventures, Cambridge Innovation Capital, Sanofi Ventures, and the University of Cambridge Venture Fund. The funds will accelerate preclinical development toward the clinic for its pipeline in cancer and autoimmune disease. The additional capital supports advancement of first-in-class TCR-CD3 bispecifics addressing undruggable targets and broadens therapeutic strategies into immunology. CEO Theodora Harold highlighted the financing as validation of the technology and progress, emphasizing pan-indication impact on upstream disease drivers.
Nov 2023Series ACambridge Innovation Capital (lead); Digitalis Ventures (lead); F-Prime (lead); Sofinnova Partners (lead); University of Cambridge Enterprise; Sanofi Ventures$61M-

Who has invested in T-Therapeutics?

15 investors have backed T-Therapeutics across its funding rounds, including F-Prime, Sofinnova Partners, Sanofi Ventures, Cambridge Innovation Capital, Digitalis Ventures and Tencent.

Lead investors include Advent Life Sciences, British Business Bank, Cambridge Innovation Capital, Digitalis Ventures, F-Prime and 1 other investor.


T-Therapeutics Investors

Investors in T-Therapeutics by funding rounds participated
InvestorHQRoundsRoleFirst check
Digitalis VenturesUnited StatesNew York City, NY3LeadNov 2023
Sofinnova PartnersFranceParis3LeadNov 2023
F-PrimeUnited StatesUnited States3LeadNov 2023
Cambridge Innovation CapitalUnited KingdomCambridge3LeadNov 2023
Sanofi VenturesUnited StatesUnited States3ParticipantNov 2023
TencentChinaShenzhen2ParticipantNov 2025
M VenturesNetherlandsAmsterdam1ParticipantNov 2026
University of Cambridge EnterpriseUnited KingdomCambridge1ParticipantNov 2023
British Business BankUnited KingdomSheffield1LeadNov 2026
Cambridge Enterprise VenturesUnited KingdomCambridge1ParticipantNov 2025
Advent Life SciencesUnited KingdomLondon1LeadNov 2026
Business Growth FundUnited KingdomLondon1ParticipantNov 2025
Eli Lilly and CompanyUnited StatesIndianapolis1ParticipantNov 2026

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T-Therapeutics Competitors

T-Therapeutics competitors include listed companies like Roche and Johnson & Johnson, and private ones like Heyuan Biotechnology, ArsenalBio, Formation Bio and Immunai.

Public and private companies comparable to T-Therapeutics
CompanyHQStatusRevenueEBITDAValuationRevenue Multiple
RocheSwitzerlandSwitzerlandPublicly listed$78B$26B$382B5.3x
Heyuan BiotechnologyChinaShanghaiPrivate--$3B-
ArsenalBioUnited StatesUnited StatesPrivate--$1.9B-
Formation BioUnited StatesNew York City, NYPrivate--$1B-
ImmunaiUnited StatesNew York City, NYPrivate--$1B-
Johnson & JohnsonUnited StatesUnited StatesPublicly listed$94B$40B$665B6.9x

T-Therapeutics Public Comps

T-Therapeutics is still privately-owned, but its public comps include Eli Lilly, Johnson & Johnson, AbbVie, Roche, Merck, Novartis, AstraZeneca, Amgen, Gilead Sciences and Novo Nordisk.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
Eli Lilly$65B$28B19.2x14.3x45.1x30.2x
Johnson & Johnson$94B$40B7.4x6.9x17.3x18.8x
AbbVie$61B$17B9.6x8.8x33.7x18.6x
Roche$78B$26B5.3x5.3x15.7x13.3x
Merck$65B$28B6.2x6.1x14.5x22.9x
Novartis$57B$22B6.1x6.1x15.9x14.8x
AstraZeneca$59B$19B5.4x5.1x16.5x14.2x
Amgen$37B$17B7.9x7.4x17.3x16.5x

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Common questions about T-Therapeutics

When was T-Therapeutics founded?T-Therapeutics was founded in 2022.
Where is T-Therapeutics headquartered?T-Therapeutics is headquartered in Cambridge, United Kingdom.
Is T-Therapeutics publicly listed?No, T-Therapeutics is a private, VC-backed company.
How much funding has T-Therapeutics raised?T-Therapeutics has raised $226M across 3 funding rounds.
What was T-Therapeutics' last funding round?T-Therapeutics' last funding round was a $133M Series B in November 2026, led by Advent Life Sciences and British Business Bank.
Who are T-Therapeutics' investors?T-Therapeutics' investors include Digitalis Ventures, Sofinnova Partners, F-Prime, Cambridge Innovation Capital, Sanofi Ventures, Tencent, M Ventures, University of Cambridge Enterprise, British Business Bank, Cambridge Enterprise Ventures and 5 others.
Which companies are comparable to T-Therapeutics?Companies comparable to T-Therapeutics include Roche, Heyuan Biotechnology, ArsenalBio, Formation Bio, Immunai and Johnson & Johnson.

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