Sironax Funding, Investors & Competitors

Sironax has raised $301M across 2 funding rounds, most recently a $200M Series B in August 2022.

Last Sironax funding round

$200M

Series B · Aug 2022

Cumulative funding Sironax raised

$301M

across 2 funding rounds

Key investors in Sironax

  • F-Prime
  • Gaorong Capital
  • YF Capital
  • Abu Dhabi Investment Authority

Sironax Overview

About Sironax

Sironax is a clinical-stage biotechnology company developing therapies for age-related degenerative diseases. It serves patients and healthcare systems that may use its medicines if clinical development and regulatory approval are successful, and its products or services sit inside day-to-day operating or consumer workflows rather than acting as a passive holding vehicle. The business earns revenue through prospective drug sales, licensing and development partnerships rather than current mass-market commercial revenue. Founded in 2017 and based in Beijing, Sironax operates across China, the United States and other research markets through discovery, clinical and regulatory programmes. Its pipeline targets regulated cell-death and inflammatory pathways associated with neurodegenerative and related diseases. The company uses small-molecule discovery and translational research and had raised more than USD 300 million in aggregate after its 2022 Series B. Customers choose the company for specialised biology, proprietary drug candidates and the ability to run multi-jurisdiction clinical programmes, while its capital base supports the people, technology, physical assets and regulatory capabilities needed to deliver those services. Its profile in this research is that of an operating company with identifiable customers and commercial revenue, even where long-term institutional shareholders own a material stake.


Founded

2017

HQ

ChinaBeijing

Status

Privately held

Customer focus

B2B

Revenue model

Licensing

Sironax Funding History

Sironax has raised a total of $301M across 2 funding rounds.

Sironax's first fundraising round was a $101M Series A in September 2019. The most recent completed round was a $200M Series B in August 2022.

Sironax funding rounds

Sironax funding rounds
DateStageInvestorsRaisedDeal Summary
Aug 2022Series BGaorong Capital (lead); YF Capital (lead); Abu Dhabi Investment Authority$200MSironax, a Beijing-based clinical-stage biotechnology company founded in 2017, develops novel treatments for age-related degenerative diseases, focusing on mechanisms like regulated cell death, neuroprotective pathways, and neuroinflammation, including receptor-interacting protein kinase 1 (RIPK1) inhibitors. The company announced the closing of its $200 million Series B financing on August 2, 2022, led jointly by Gaorong Capital and Yunfeng Capital (also referred to as YF Capital), bringing total fundraising to over $300 million. Existing investors participating included Temasek, Invus, F-Prime Capital, Eight Roads, ARCH Venture Partners, and K2 Venture Partners, while new investors comprised MSA Capital (a subsidiary of Abu Dhabi Investment Authority), CBC Group, Long River Investments, LSV Capital, Superstring Capital, and Future Innovation Fund. Proceeds will fund clinical development of RIPK1 inhibitors and expansion of R&D scale and pipeline for degenerative diseases. Sironax's pipeline has shown strong safety profiles and promising efficacy in early clinical trials, positioning it as a fast-growing player in therapies for conditions like Alzheimer's and other neurodegenerative diseases. The company continues advancing its programs, with mentions of partnerships like with X-Chem for neurodegenerative drug discovery.
Sep 2019Series AF-Prime$101M-

Who has invested in Sironax?

4 investors have backed Sironax across its funding rounds, including F-Prime, Gaorong Capital, YF Capital and Abu Dhabi Investment Authority.

Lead investors include Gaorong Capital and YF Capital.


Sironax Investors

Investors in Sironax by funding rounds participated
InvestorHQRoundsRoleFirst check
YF CapitalChinaShanghai1LeadAug 2022
Abu Dhabi Investment AuthorityUAEAbu Dhabi1ParticipantAug 2022

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Sironax Competitors

Sironax competitors include listed companies like Roche and Johnson & Johnson, and private ones like Heyuan Biotechnology, ArsenalBio, Formation Bio and Immunai.

Public and private companies comparable to Sironax
CompanyHQStatusRevenueEBITDAValuationRevenue Multiple
RocheSwitzerlandSwitzerlandPublicly listed$78B$26B$382B5.3x
Heyuan BiotechnologyChinaShanghaiPrivate--$3B-
ArsenalBioUnited StatesUnited StatesPrivate--$1.9B-
Formation BioUnited StatesNew York City, NYPrivate--$1B-
ImmunaiUnited StatesNew York City, NYPrivate--$1B-
Johnson & JohnsonUnited StatesUnited StatesPublicly listed$94B$40B$665B6.9x

Sironax Public Comps

Sironax is still privately-owned, but its public comps include Eli Lilly, Johnson & Johnson, AbbVie, Roche, Merck, Novartis, AstraZeneca, Amgen, Gilead Sciences and Novo Nordisk.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
Eli Lilly$65B$28B19.2x14.3x45.1x30.1x
Johnson & Johnson$94B$40B7.4x6.9x17.3x18.8x
AbbVie$61B$17B9.6x8.8x33.7x18.6x
Roche$78B$26B5.3x5.3x15.7x13.3x
Merck$65B$28B6.2x6.1x14.5x23.0x
Novartis$57B$22B6.1x6.1x15.9x14.8x
AstraZeneca$59B$19B5.4x5.1x16.5x14.2x
Amgen$37B$17B7.9x7.4x17.3x16.5x

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Common questions about Sironax

When was Sironax founded?Sironax was founded in 2017.
Where is Sironax headquartered?Sironax is headquartered in Beijing, China.
Is Sironax publicly listed?No, Sironax is a private, VC-backed company.
How much funding has Sironax raised?Sironax has raised $301M across 2 funding rounds.
What was Sironax's last funding round?Sironax's last funding round was a $200M Series B in August 2022, led by Gaorong Capital and YF Capital.
Who are Sironax's investors?Sironax's investors include YF Capital, Abu Dhabi Investment Authority, Gaorong Capital and F-Prime.
Which companies are comparable to Sironax?Companies comparable to Sironax include Roche, Heyuan Biotechnology, ArsenalBio, Formation Bio, Immunai and Johnson & Johnson.

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