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- Owlstone Medical
Owlstone Medical Funding, Investors & Competitors
Owlstone Medical has raised $166M across 10 funding rounds, most recently a $2M seed round in March 2025.
Last Owlstone Medical funding round
$2M
Seed · Mar 2025
Cumulative funding Owlstone Medical raised
$166M
across 10 funding rounds
Key investors in Owlstone Medical
Horizons Ventures
Aviva Ventures
Ventura Capital
Foxconn
Bill & Melinda Gates Foundation
Cystic Fibrosis Foundation
V Ventures
Medtekwiz Advisory Ltd
About Owlstone Medical
Owlstone Medical is a Cambridge-based company that develops the Breath Biopsy platform for non-invasive disease detection through breath analysis. The technology identifies volatile organic compounds as biomarkers for cancers including lung, ovarian, and liver, as well as tuberculosis and inflammatory diseases. Backed by partnerships with AstraZeneca, the NHS, and the FDA which granted breakthrough device designation for kidney cancer testing in 2022, the firm operates from its headquarters in the UK with a US presence in Research Triangle Park, North Carolina. Founded in 2004 as a spin-out from the University of Cambridge, Owlstone Medical has raised over $100 million in funding and collaborates with global pharmaceutical companies for clinical trials.
Founded
2004
HQ
Website
Status
Privately held
Customer focus
B2B
Revenue model
Product sales
Owlstone Medical Funding History
Owlstone Medical has raised a total of $166M across 10 funding rounds.
Owlstone Medical's first fundraising round was a $2M strategic investment round in February 2016. The most recent completed round was a $2M seed round in March 2025.
Owlstone Medical funding rounds
| Date | Stage | Investors | Raised | Deal Summary |
|---|---|---|---|---|
| Mar 2025 | Seed | Cystic Fibrosis Foundation (lead) | $2M | Owlstone Medical received an equity investment of up to USD $2.3 million (circa £1.7 million) from the Cystic Fibrosis Foundation on March 25, 2025. The funding supports development of a breath test for Pseudomonas aeruginosa detection in cystic fibrosis patients, suitable for both new cases and monitoring chronic infections. Owlstone leverages its Breath Biopsy platform and expertise in volatile organic compound analysis to achieve diagnostic accuracy comparable to sputum culture tests while distinguishing PA from other pathogens like S. aureus. The investment focuses initially on proof-of-principle for chronic PA infection identification via breath VOCs for long-term monitoring. Data from the study will contribute to Owlstone's Breath VOC Atlas for broader biomarker and test development. Owlstone Medical positions itself as a leader in breath-based diagnostics for early disease detection and precision medicine, with prior projects including collaborations with the U.S. Department of Defense and Gates Foundation. This follows Owlstone's Series E first close of $27 million in January 2025, led by Ventura Capital with Aviva Ventures, Horizons Ventures, and Gates Foundation, aimed at commercializing Breath Biopsy tests for lung cancer, liver disease, and digestive diseases. |
| Jan 2025 | Series E | Ventura Capital (lead); Horizons Ventures; Aviva Ventures | $27M | Owlstone Medical is a Cambridge, UK-based company specializing in Breath Biopsy® for early disease detection and precision medicine, including applications for lung cancer, liver disease, digestive diseases, infectious diseases like Pseudomonas aeruginosa in cystic fibrosis patients, and partnerships with the U.S. Department of Defense, Gates Foundation, and FDA. The platform features the ReCIVA® sample collection device, a commercial Breath Biopsy Laboratory in Cambridge, and the VOC Atlas® database, with products approved in the US and UK markets. On January 15, 2025, Owlstone Medical announced the first closing of its Series E financing round at $27 million USD (circa £22 million), led by Ventura Capital and joined by Aviva Ventures, Horizons Ventures, existing investors, and the Gates Foundation. The funding aims to accelerate commercialization and clinical trials of Breath Biopsy diagnostic tests and point-of-care devices. |
| Apr 2024 | Series A | Bill & Melinda Gates Foundation (lead) | $5M | Owlstone Medical secured $6.5 million in total funding from the Bill & Melinda Gates Foundation on April 25, 2024, comprising a $5 million equity investment and $1.5 million grant. The equity investment advances the Breath Biopsy platform, including expansion of the VOC Atlas database and development of a remote-use real-time breath analyzer. The grant supports breath-based diagnostics and identification of biomarkers for tuberculosis and HIV to improve outcomes in developing regions. This marked the foundation's first equity position in a breath diagnostics company. Owlstone Medical leads in Breath Biopsy for early disease detection and precision medicine. |
| Sep 2021 | Series D | Horizons Ventures (lead) | $57M | Owlstone Medical, a Cambridge, UK-based company and global leader in Breath Biopsy for early disease detection and precision medicine, closed an oversubscribed Series D financing round on September 7, 2021, raising $58 million (c. £42 million), exceeding its $50 million target. The round was led by returning investor Horizons Ventures, which joined the board, and included other existing and new high-profile investors from Asia, the Middle East, and the United States, bringing total funding since 2016 to over $150 million (c. £109 million). Proceeds will fund further Breath Biopsy platform development and commercialization of proprietary tests for lung cancer, liver disease, respiratory disease, and digestive health. Key progress highlighted includes advancements in the Breath Biopsy platform with EVOC Probes, launch of the Respiratory Diseases RUO Panel, publication of liver disease study results, and a partnership with Functional Gut Diagnostics for SIBO and food intolerance clinical tests. CEO Billy Boyle emphasized the company's market-leading position in early detection and precision medicine. Horizons Ventures' Patrick Zhang praised the non-invasive biomarker potential for healthcare screening and diagnostics. Owlstone Medical originated as a 2016 spin-out from Owlstone Inc., leveraging Field Asymmetric Ion Mobility Spectrometry (FAIMS) technology for medical applications from its military and industrial chemical sensing base. The company has prior funding history, including a 2018 $15 million round co-led by Horizons Ventures and Aviva Ventures. Subsequent developments include a 2025 Series E first close of $27 million led by Ventura Capital with participation from Aviva Ventures, Horizons Ventures, and the Gates Foundation, plus earlier Gates Foundation equity and grant funding for TB and HIV breath diagnostics. |
| Oct 2018 | Undisclosed stage | Horizons Ventures (lead); Foxconn; Ventura Capital | $35M | Owlstone Medical, a Cambridge, UK-based diagnostics company spun out of Owlstone Inc. in 2016, develops the Breath Biopsy platform using proprietary Field Asymmetric Ion Mobility Spectrometry (FAIMS) technology for early disease detection and precision medicine, including lung cancer tests and services for the pharmaceutical industry. The company completed a $50 million total financing round in October 2018, consisting of a first phase of $15 million announced in March 2018 led by Aviva Ventures and Horizons Ventures, followed by a second phase of $35 million also led by Horizons Ventures with participation from strategic investors including Ventura Capital and Foxconn Technologies Group, bringing cumulative funding to about $73 million since founding. The funds were allocated to global commercialization of targeted Breath Biopsy kits, technology platform development for high-value applications, lung cancer test market launch, early detection pipeline expansion across cancers, and growth in precision medicine services. Horizons Ventures expressed strong confidence in Owlstone's potential to transform early cancer detection and precision medicine, citing its unique positioning. The round attracted global strategic interest to support commercial and development activities, with Aviva Ventures continuing as a key backer focused on the technology's importance for health insurance and early screening. Owlstone Medical has continued fundraising in later years, including a Series E first close of $27 million in January 2025 led by Ventura Capital with Aviva Ventures, Horizons Ventures, and the Gates Foundation to accelerate commercialization and clinical trials for lung cancer, liver disease, and digestive disease diagnostics, but this is distinct from the 2018 round. |
| Mar 2018 | Series A | Aviva Ventures (lead); Horizons Ventures (lead) | $15M | Owlstone Medical raised $15 million in the first phase of a financing round on March 5, 2018, co-led by Horizons Ventures and Aviva Ventures, with participation from existing backers including Medtekwiz. This funding supported the commercialization of its Breath Biopsy platform, which uses proprietary Field Asymmetric Ion Mobility Spectrometry (FAIMS) technology for early disease detection, particularly cancer, through breath analysis. The company, spun out of Owlstone Inc. in 2016, had raised a total of $38.5 million in equity financing by that point. The second phase of the round, announced later in 2018, added $35 million led by Horizons Ventures with investors including Ventura Capital and Foxconn Technologies Group, bringing the total to $50 million. |
| Mar 2017 | Seed | Aviva Ventures (lead) | $5M | Owlstone Medical, a diagnostics company spun out from Owlstone Inc in 2016, develops the Breath Biopsy platform—a breathalyzer for early disease detection including lung and colorectal cancer. On March 27, 2017, Aviva Ventures invested in Owlstone Medical to drive test adoption and commercialization of the Breath Biopsy platform. The investment brought the company's total funding to $23.5 million USD (£19.3 million GBP) since spin-out. Aviva Ventures identified the platform as strategically important and planned to promote it in healthcare. |
| Jan 2017 | Series A | - | $12M | Owlstone Medical is a Cambridge, UK-based diagnostics company developing a Breath Biopsy platform using ion mobility spectrometry technology for early disease detection and precision medicine. The company spun out from Owlstone Inc in June 2016 with an initial $7 million investment. In January 2017, Owlstone Medical raised $11.55 million (£9.3 million) in a round led by existing investors, bringing total funding to approximately $18.55 million at that time. By March 2017, the company had secured an additional $5 million investment from Aviva Ventures, increasing total funding to $23.5 million since the 2016 spin-out. The capital was deployed to commercially launch breath biomarker research and development services, open a new high-volume clinical facility, and fund clinical trials including the LuCID lung cancer study, which aimed to recruit up to 3,000 patients across 21 sites in the UK and Europe. |
| Jun 2016 | Series A | Medtekwiz Advisory Ltd (lead) | $7M | Owlstone Medical, a Cambridge-based diagnostics company, closed a $7 million (£4.9 million) financing round led by private investment fund Medtekwiz Advisory Ltd on 28 June 2016. The company had been spun out from parent company Owlstone Inc in 2016 to develop and commercialize medical applications of proprietary microchip chemical sensing technology, specifically a breathalyzer platform for clinical diagnostics and precision medicine. The investment was designated to fund ongoing clinical trials of the Breath Biopsy platform for lung and colon cancer screening. This round represented an early stage of development for the company; subsequent funding rounds in 2017 and 2018 would bring the company significantly larger capital infusions, ultimately leading to reported total funding of $205.7 million by 2025. |
| Feb 2016 | Strategic investment | V Ventures | $2M | - |
Who has invested in Owlstone Medical?
8 investors have backed Owlstone Medical across its funding rounds, including Horizons Ventures, Aviva Ventures, Ventura Capital, Foxconn, Bill & Melinda Gates Foundation and Cystic Fibrosis Foundation.
Lead investors include Cystic Fibrosis Foundation, Ventura Capital, Bill & Melinda Gates Foundation, Horizons Ventures, Aviva Ventures and 1 other investor.
Owlstone Medical Investors
| Investor | HQ | Rounds | Role | First check |
|---|---|---|---|---|
| 4 | Lead | Mar 2018 | ||
| 3 | Lead | Mar 2017 | ||
| 2 | Lead | Oct 2018 | ||
| 1 | Participant | Oct 2018 | ||
| 1 | Participant | Feb 2016 | ||
| 1 | Lead | Apr 2024 | ||
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Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples
Sign up to see data on 350K+ funding rounds and disclosed revenue and EBITDA valuation multiples, from seed, through growth stage, to pre-IPO.
Start Free TrialOwlstone Medical Competitors
Owlstone Medical competitors include listed companies like Illumina, BillionToOne, Roche and 10x Genomics, and private ones like ArsenalBio and BGI Group.
| Company | HQ | Status | Revenue | EBITDA | Valuation | Revenue Multiple |
|---|---|---|---|---|---|---|
| Publicly listed | $4.3B | $1.4B | $37B | 8.4x | ||
| Publicly listed | $305M | $12M | $5.2B | 11.7x | ||
| Publicly listed | $77B | $26B | $351B | 4.9x | ||
| Publicly listed | $643M | ($16M) | $10B | 15.2x | ||
| Private | - | - | $1.9B | - | ||
| Private | - | - | $1.6B | - |
Owlstone Medical Public Comps
Owlstone Medical is still privately-owned, but its public comps include Samsung, Johnson & Johnson, Roche, Thermo Fisher Scientific, Siemens, Abbott, Danaher, Intuitive Surgical, Medtronic and Stryker.
| Last FY | EV/Revenue | EV/EBITDA | ||||||
|---|---|---|---|---|---|---|---|---|
| Revenue | EBITDA | Last FY | LTM | 2027E | Last FY | LTM | 2027E | |
| $243B | $67B | 4.4x | 2.4x | 15.8x | 4.4x | |||
| $94B | $40B | 7.2x | 6.8x | 17.0x | 18.3x | |||
| $77B | $26B | 5.0x | 4.9x | 14.6x | 12.4x | |||
| $45B | $11B | 6.3x | 6.0x | 26.8x | 23.6x | |||
| $91B | $15B | 3.0x | 2.9x | 18.1x | 15.7x | |||
| $44B | $12B | 4.6x | 4.2x | 17.4x | 15.8x | |||
| $25B | $6.9B | 7.0x | 6.6x | 24.8x | 21.1x | |||
| $10B | $3.6B | 13.0x | 11.6x | 36.6x | 25.7x | |||
This data is available for Pro users. Sign up to see all Owlstone Medical competitors and their valuation data. Start Free Trial | ||||||||
Common questions about Owlstone Medical
| When was Owlstone Medical founded? | Owlstone Medical was founded in 2004. |
| Where is Owlstone Medical headquartered? | Owlstone Medical is headquartered in Cambridge, United Kingdom. |
| Is Owlstone Medical publicly listed? | No, Owlstone Medical is a private, VC-backed company. |
| How much funding has Owlstone Medical raised? | Owlstone Medical has raised $166M across 10 funding rounds. |
| What was Owlstone Medical's last funding round? | Owlstone Medical's last funding round was a $2M seed round in March 2025, led by Cystic Fibrosis Foundation. |
| Who are Owlstone Medical's investors? | Owlstone Medical's investors include Horizons Ventures, Aviva Ventures, Ventura Capital, Foxconn, V Ventures, Bill & Melinda Gates Foundation, Medtekwiz Advisory Ltd and Cystic Fibrosis Foundation. |
| Which companies are comparable to Owlstone Medical? | Companies comparable to Owlstone Medical include Illumina, BillionToOne, Roche, 10x Genomics, ArsenalBio and BGI Group. |
See companies similar to Owlstone Medical
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