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- OMass Therapeutics
OMass Therapeutics Funding, Investors & Competitors
OMass Therapeutics has raised $472M across 6 funding rounds, most recently a $310M Series C in October 2026.
Last OMass Therapeutics funding round
$310M
Series C · Oct 2026
Cumulative funding OMass Therapeutics raised
$472M
across 6 funding rounds
Key investors in OMass Therapeutics
Oxford Science Enterprises
Syncona
GV
Northpond Ventures
Sanofi Ventures
University of Oxford
Novo Holdings
Forbion Capital Partners
About OMass Therapeutics
OMass Therapeutics is an Oxford-based biotechnology firm founded in 2016 that pioneers drug discovery through proprietary native mass spectrometry technologies. The company targets difficult proteins such as membrane proteins and protein complexes for therapeutics in immunology and rare diseases. Its OMass platform enables intact protein analysis to identify optimal drug candidates with high specificity. OMass Therapeutics collaborates with leading research institutions and advances pipelines against GPCR and ion channel targets.
Founded
2016
HQ
Website
Status
Privately held
Customer focus
B2B
Revenue model
Licensing
OMass Therapeutics Funding History
OMass Therapeutics has raised a total of $472M across 6 funding rounds.
OMass Therapeutics' first fundraising round was a $1M seed round in June 2016. The most recent completed round was a $310M Series C in October 2026.
OMass Therapeutics funding rounds
| Date | Stage | Investors | Raised | Deal Summary |
|---|---|---|---|---|
| Oct 2026 | Series C | Bain Capital Life Sciences (lead); Novo Holdings (lead); Northpond Ventures; SV Health Investors; University of Oxford; GV; British Business Bank; Jefferson Life Sciences; Oxford Science Enterprises; Janus Henderson; Forbion Capital Partners; Sanofi Ventures; Syncona | $310M | OMass Therapeutics announced an oversubscribed USD 310 million (GBP 230 million) Series C financing round on 15 October 2026. The round was co-led by new investors Bain Capital Life Sciences, Forbion and Novo Holdings, with additional participation from Janus Henderson Investors, SV Health Investors and Jefferson Life Sciences. All existing investors also took part, including Syncona, Oxford Science Enterprises, GV, Northpond Ventures, Sanofi Ventures, British Business Bank and the University of Oxford. Syncona committed USD 10.1 million to the round. Proceeds will support Phase 2 development of the lead program OMS1620 in congenital adrenal hyperplasia and the earlier-stage pipeline, including an SLC15A4 inhibitor for lupus. Chief executive Ros Deegan said the financing comes at an exciting point as OMass advances OMS1620 into the clinic. OMass is headquartered in Oxford, UK, and was founded as a spin-out from Professor Dame Carol Robinson's laboratory at the University of Oxford to translate native mass spectrometry research into drug discovery. It develops small molecule therapeutics against validated target ecosystems and signed a collaboration with Genentech in September 2025 that carried a USD 20 million upfront payment. Its earlier rounds included a USD 100 million Series B in 2022. |
| May 2023 | Series B | British Patient Capital (lead) | $12M | OMass Therapeutics is an Oxford-based platform therapeutics company spun out from the University of Oxford that discovers and develops novel small molecule medicines targeting hard-to-drug proteins using native mass spectrometry for areas of high unmet need in immunology and rare diseases. The company advances therapeutics against solute carriers, complex-bound proteins, and GPCRs, with a pipeline including programs for congenital adrenal hyperplasia, ACTH-dependent Cushing’s, GPR65, SLC15A4, and cGAS. OMass reported no revenue in 2023 alongside an EBITDA loss of GBP 28,579,921, generating potential future revenue through strategic partnerships involving milestone payments and royalties. On May 15, 2023, British Patient Capital invested £10 million in OMass Therapeutics’ Series B extension, increasing the total round to £85.5 million after prior leadership from GV, Sanofi Ventures, and Northpond Ventures, with participation from Syncona and Oxford Science Enterprises. The funding supports pipeline advancement toward clinical trials, facility expansion to a new ARC Oxford Campus site, and leadership additions including Winfried Barchet as VP of Immunology, Julia Sampson as VP of Non-clinical Development, Melissa Faris as Chief Business Officer, and Jim Geraghty as Independent Board Chair. |
| Apr 2022 | Series B | GV (lead); Northpond Ventures (lead); Sanofi Ventures (lead); University of Oxford; Oxford Science Enterprises; Syncona | $95M | OMass Therapeutics, a University of Oxford spin-off founded in 2016, develops small-molecule therapeutics targeting hard-to-drug membrane proteins and complex-bound proteins using its proprietary OdyssION platform, which integrates native mass spectrometry, biochemistry, and custom chemistry. The company's pipeline focuses on rare diseases and immunology, including a best-in-class MC2 receptor antagonist for congenital adrenal hyperplasia and ACTH-dependent Cushing’s syndrome, programs targeting gasdermin D for inflammatory diseases, and GPR65 for inflammatory bowel disease. On April 28, 2022, OMass announced a $100 million (£75.5 million) Series B financing round led by GV (formerly Google Ventures), Northpond Ventures, and Sanofi Ventures, with participation from existing investors Syncona, Oxford Science Enterprises, and University of Oxford. This round, one of the largest biotech Series B financings in the UK at the time, aimed to advance the company's portfolio of five preclinical programs toward clinical development. New board members included Scott Biller from GV, Diana Bernstein from Northpond Ventures, and Laia Crespo from Sanofi Ventures. The funding supported progression of novel drugs against validated but intractable targets like solute carriers, complex-bound proteins, and GPCRs. By mid-2025, OMass had raised over $160 million in total funding. In September 2025, it entered an exclusive collaboration with Genentech, receiving $20 million upfront and up to $400 million in milestones for a preclinical oral small-molecule IBD program. |
| Feb 2020 | Series A | Syncona (lead); Oxford Science Enterprises | $35M | OMass Therapeutics, a biotechnology company based in Oxford, UK, leverages native mass spectrometry to enable high-definition drug discovery, particularly for membrane protein targets like GPCRs in immunological and genetic disorders. On February 17, 2020, it completed an extended Series A financing of £27.5 million, led by Syncona (£16.6 million) and Oxford Sciences Innovation (£10.4 million), with £0.5 million from the University of Oxford. This followed an initial £14 million Series A in 2018, bringing the total Series A to £41.5 million (approximately US$35.8 million). The funds provide a two-year runway to advance programs against three high-impact GPCR targets toward preclinical development. Syncona, a life sciences investor, views OMass as a leader in native mass spectrometry for studying non-covalent interactions with membrane proteins. The technology originates from Prof. Dame Carol Robinson's academic group. At the time, OMass had initiated drug discovery programs focused on genetically defined patient populations and immunological dysfunction, aiming to deliver novel small molecule therapeutics. |
| Nov 2018 | Series A | Syncona (lead); Oxford Science Enterprises | $18M | OMass Therapeutics is a biopharmaceutical company using structural mass spectrometry to discover novel medicines targeting large protein complexes. On November 20, 2018, it completed a £14 million ($18 million) Series A financing led by Syncona, alongside Oxford Sciences Innovation (now Oxford Science Enterprises). The funding supports development of a pipeline of drug development programs leveraging OMass's proprietary technology. Syncona, a FTSE250 healthcare company, partnered with OMass to build global leaders in life sciences. Oxford Sciences Innovation, backed by investors like GV, Sequoia, and the Wellcome Trust, focuses on deep science from the University of Oxford. Dr. Jonathan Hopper, Founder and CEO, highlighted the financing's role in building innovative medicines, while Professor Dame Carol Robinson, Founder and Scientific Advisor, emphasized the power of mass spectrometry approaches. This initial Series A was later extended, with an additional £27.5 million announced, bringing the total Series A to £41.5 million. OMass has since raised further rounds, including a $100 million (£75.5 million) Series B in April 2022 led by GV, Northpond Ventures, and Sanofi Ventures, with participation from Syncona and others. |
| Jun 2016 | Seed | Oxford Science Enterprises (lead) | $1M | - |
Who has invested in OMass Therapeutics?
14 investors have backed OMass Therapeutics across its funding rounds, including Oxford Science Enterprises, Syncona, GV, Northpond Ventures, Sanofi Ventures and University of Oxford.
Lead investors include Bain Capital Life Sciences, Novo Holdings, British Patient Capital, GV, Northpond Ventures and 3 other investors.
OMass Therapeutics Investors
| Investor | HQ | Rounds | Role | First check |
|---|---|---|---|---|
| 5 | Lead | Jun 2016 | ||
| 4 | Lead | Nov 2018 | ||
| 2 | Lead | Apr 2022 | ||
| 2 | Participant | Apr 2022 | ||
| 2 | Lead | Apr 2022 | ||
| 2 | Lead | Apr 2022 | ||
| 1 | Lead | Oct 2026 | ||
| 1 | Participant | Oct 2026 | ||
| 1 | Participant | Oct 2026 | ||
| -- | 1 | Participant | Oct 2026 | |
| 1 | Participant | Oct 2026 | ||
| 1 | Lead | Oct 2026 | ||
This data is available for Pro users. Sign up to see all 14 OMass Therapeutics investors. Start Free Trial | ||||
Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples
Sign up to see data on 350K+ funding rounds and disclosed revenue and EBITDA valuation multiples, from seed, through growth stage, to pre-IPO.
Start Free TrialOMass Therapeutics Competitors
OMass Therapeutics competitors include listed companies like Lonza Group and Laurus Labs, and private ones like BioRay Pharmaceuticals, Belief BioMed, Letu and BDR Pharma.
| Company | HQ | Status | Revenue | EBITDA | Valuation | Revenue Multiple |
|---|---|---|---|---|---|---|
| Publicly listed | $7.9B | $2.5B | $55B | 6.8x | ||
| Publicly listed | $707M | $191M | $14B | 16.8x | ||
| Private | $131M | - | $1.9B | 14.5x | ||
| Private | - | - | $1.3B | - | ||
| Private | - | - | $1.1B | - | ||
| Private | $155M | $52M | $949M | 6.1x |
OMass Therapeutics Public Comps
OMass Therapeutics is still privately-owned, but its public comps include Eli Lilly, Johnson & Johnson, AbbVie, Roche, Merck, Novartis, AstraZeneca, Amgen, Gilead Sciences and Novo Nordisk.
| Last FY | EV/Revenue | EV/EBITDA | ||||||
|---|---|---|---|---|---|---|---|---|
| Revenue | EBITDA | Last FY | LTM | 2027E | Last FY | LTM | 2027E | |
| $65B | $28B | 20.1x | 15.1x | 47.1x | 32.2x | |||
| $94B | $40B | 7.3x | 6.8x | 17.1x | 18.6x | |||
| $61B | $17B | 9.6x | 8.8x | 33.7x | 18.7x | |||
| $77B | $26B | 5.5x | 5.4x | 16.2x | 13.7x | |||
| $65B | $28B | 6.4x | 6.2x | 14.9x | 23.1x | |||
| $57B | $22B | 6.1x | 6.1x | 15.8x | 14.8x | |||
| $59B | $19B | 5.4x | 5.1x | 16.5x | 14.1x | |||
| $37B | $17B | 8.0x | 7.6x | 17.6x | 16.8x | |||
This data is available for Pro users. Sign up to see all OMass Therapeutics competitors and their valuation data. Start Free Trial | ||||||||
Common questions about OMass Therapeutics
| When was OMass Therapeutics founded? | OMass Therapeutics was founded in 2016. |
| Where is OMass Therapeutics headquartered? | OMass Therapeutics is headquartered in Oxford, United Kingdom. |
| Is OMass Therapeutics publicly listed? | No, OMass Therapeutics is a private, VC-backed company. |
| How much funding has OMass Therapeutics raised? | OMass Therapeutics has raised $472M across 6 funding rounds. |
| What was OMass Therapeutics' last funding round? | OMass Therapeutics' last funding round was a $310M Series C in October 2026, led by Bain Capital Life Sciences and Novo Holdings. |
| Who are OMass Therapeutics' investors? | OMass Therapeutics' investors include Oxford Science Enterprises, Syncona, Northpond Ventures, University of Oxford, GV, Sanofi Ventures, Novo Holdings, SV Health Investors, British Business Bank, Jefferson Life Sciences and 4 others. |
| Which companies are comparable to OMass Therapeutics? | Companies comparable to OMass Therapeutics include Lonza Group, Laurus Labs, BioRay Pharmaceuticals, Belief BioMed, Letu and BDR Pharma. |
See companies similar to OMass Therapeutics
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