Human Longevity Valuation, Funding & Investors

Human Longevity is valued at $186M as of August 2024.

Last Human Longevity valuation

$186M

Series B · Aug 2024

Last Human Longevity funding round

$40M

Series B · Aug 2024

Cumulative funding Human Longevity raised

$370M

across 4 funding rounds

Key investors in Human Longevity

  • Celgene
  • OS Fund
  • Panacea Venture
  • Emerging Technology Partners
  • GE Ventures
  • Threshold

Human Longevity Overview

About Human Longevity

Human Longevity is a San Diego-headquartered genomic health intelligence company founded in 2013. It operates the Health Nucleus clinical research center, utilizing whole-genome sequencing, advanced imaging, and machine learning alongside phenotypic data for comprehensive health assessments. Offerings include HLIQ Whole Genome and HLIQ Oncology services, enabling proactive medicine through the world's largest integrated genomic and clinical database.


Founded

2013

HQ

United StatesSan Diego, CA

Status

Privately held

Customer focus

B2C

Revenue model

Product sales

Valuation

$186M (Aug 2024)

Human Longevity Valuation

Human Longevity is currently valued at $186M, based on its Series B in August 2024.

The $40M round was led by TVM Capital Healthcare, with participation from Panacea Venture and Emerging Technology Partners.

Human Longevity's valuation has moved from $1.2B at its Series B in April 2016 to $186M in August 2024, across 3 priced rounds.

Human Longevity valuation by funding round

Human Longevity valuation by funding round
DateStageValuation
Aug 2024Series B$186M
Nov 2019Series B$310M
Apr 2016Series B$1.2B

Human Longevity Funding History

Human Longevity has raised a total of $370M across 4 funding rounds.

Human Longevity's first fundraising round was a $80M Series A in March 2014. The most recent completed round was a $40M Series B in August 2024.

Human Longevity funding rounds

Human Longevity funding rounds
DateStageInvestorsRaisedValuationDeal Summary
Aug 2024Series BTVM Capital Healthcare (lead); Panacea Venture; Emerging Technology Partners$40M$186MHuman Longevity, Inc. (HLI), founded in 2013 and based in San Francisco with roots in San Diego, is a longevity-focused technology company advancing precision medicine for healthy aging. The company offers the 100+ Longevity Care membership program, which includes whole-genome sequencing, whole-body and brain MRI, comprehensive cardiac evaluation, body composition analysis, advanced blood biomarkers, and wearables to detect early-stage age-related diseases like cancer, cardiovascular disease, neurodegenerative disorders, and metabolic diseases. HLI's AI-powered health risk and recommendation platform enables pre-symptomatic diagnosis, personalized treatments, and proactive interventions to extend healthspan and reduce healthcare costs. On August 21, 2024, HLI completed an oversubscribed $39.8 million upsized Series B funding round (also referred to as Series B-1 or Series B - III), led by TVM Capital Healthcare with participation from Panacea Venture and Emerging Technology Partners. The investment, announced publicly on September 18, 2024, supports U.S. market growth, expansion into Saudi Arabia and Southeast Asia, enhancements to the AI platform, development of new longevity technologies and services, and global site expansions. Forge Global reports a post-money valuation of $185.79 million for this round. HLI has raised over $376 million across multiple rounds, with prior funding from investors like Threshold, StartUp Health, OS Fund, Illumina Ventures, GE Ventures, Celgene, and Amino Capital. The company has published significant research, including 2020 work in the Proceedings of the National Academy of Sciences on integrating genomics, metabolomics, and imaging for health risk identification. Collaborations with Mass General Hospital and accreditations like Joint Commission International bolster its clinical credibility in shifting healthcare toward predictive, preventive models.
Nov 2019Series BEmerging Technology Partners (lead); Panacea Venture$30M$310MHuman Longevity, Inc. (HLI) is a San Diego-based company founded in 2013 by Peter Diamandis and Craig Venter, specializing in precision health intelligence through its Health Nucleus platform. The platform integrates whole genome sequencing, advanced imaging (MRI, cardiac CT), metabolic tests, and AI/machine learning to provide comprehensive health assessments, risk analyses for cardiac, cancer, metabolic, and cognitive issues, and personalized insights for physicians and patients. Health Nucleus assessments are offered in La Jolla, CA, with packages ranging from basic to platinum levels. In November 2019, HLI closed a $30 million financing round led by existing investor Emerging Technology Partners (ETP), with participation from Panacea Venture and other healthcare investors. The funds were earmarked to enhance the Health Nucleus platform, focusing on AI-driven metrics for health and performance measurement. This appears to be a Series B-III round, following prior funding that brought total capital raised to approximately $330 million by 2019. The company has faced challenges, including founder departures and valuation adjustments, but continued operations with initiatives like the 100+ Longevity Program launched in 2020. Later developments include a planned SPAC IPO at $1 billion valuation in 2022 and a non-binding LOI with Freedom Acquisition 1 for a $1 billion combination.
Apr 2016Series BIllumina Ventures (lead); Amino Capital; StartUp Health; GE Ventures; Celgene; OS Fund; Threshold$220M$1.2BHuman Longevity Inc. (HLI), founded in 2013 by J. Craig Venter, Robert Hariri, and Peter Diamandis, focuses on leveraging genomics, machine learning, and big data to revolutionize healthcare, particularly in predicting and extending human lifespan through early disease detection. The company operates genome sequencing centers capable of processing up to 100,000 genomes annually by end-2015, with plans to scale to 1 million, and maintains a vast database integrating genomic and phenotypic data for pharmaceutical companies, insurers, and healthcare providers. Revenue streams include database licensing to pharma, biotech, and academic organizations, plus services like exome, genome, and cancer sequencing, such as partnerships with Discovery Insurance in South Africa and the UK. In April 2016, HLI completed a $220 million Series B financing round, led by Illumina Ventures, with participation from investors including Celgene, GE Ventures, Amino Capital, OS Fund, StartUp Health, and Threshold, bringing total funding to around $300 million following an initial $80 million Series A in 2014. The post-money valuation was $1.2 billion, as reported in contemporary coverage. Funds were earmarked for developing the Health Nucleus—a genomics research health center combining whole genome sequencing, clinical imaging, and AI-driven analysis—and expanding the HLI Knowledgebase, which held over 20,000 complete genomes with phenotype data at the time, alongside oncology genomics programs like liquid biopsies and cancer vaccines. HLI aimed to commercialize precision medicine offerings, moving beyond high-end services to broader markets by reducing costs in genomics and MRI, with ambitions to go public. The company had already sequenced nearly 40,000 whole genomes annually and secured equipment like Illumina's HiSeq X Ten systems. Subsequent challenges included executive departures and a valuation drop, leading to a $30 million raise post-2016, but the 2016 round marked a peak in investor confidence amid a genomics boom.
Mar 2014Series ADaniel Curran; Tan Thay; Viridos; Celgene; Illumina; OS Fund; Singularity University Ventures$80M-Human Longevity, Inc. was founded in 2013 by Craig Venter, Robert Hariri, and Peter Diamandis with the goal of building the world's most comprehensive database of human genotypes and phenotypes and applying machine learning to help develop new treatments for age-related diseases. The company's flagship initiative is Health Nucleus, a genomic-enhanced health center that combines whole-genome sequencing with advanced imaging and clinical data analysis. In summer 2014, Human Longevity closed its Series A financing round of $80 million from investors including Celgene, Illumina, and other international backers. The company intended to use these proceeds to establish the world's largest human genome sequencing center. By 2016, Human Longevity had expanded its business model to include commercial offerings and specialized programs such as a Comprehensive Cancer Program offering whole germline and tumor genome analysis, as well as research into liquid biopsies for circulating cancer cell DNA detection and cancer vaccines. The company subsequently closed a Series B round of $220 million in April 2016, and by 2017 was valued at $1.2 billion, though it later experienced significant valuation declines in subsequent years.

Who has invested in Human Longevity?

15 investors have backed Human Longevity across its funding rounds, including Celgene, OS Fund, Panacea Venture, Emerging Technology Partners, GE Ventures and Threshold.

Lead investors include TVM Capital Healthcare, Emerging Technology Partners and Illumina Ventures.


Human Longevity Investors

Investors in Human Longevity by funding rounds participated
InvestorHQRoundsRoleFirst check
Panacea VentureCayman IslandsGeorge Town2ParticipantNov 2019
CelgeneUnited StatesSummit, NJ2ParticipantMar 2014
Emerging Technology PartnersNew ZealandAuckland2LeadNov 2019
OS FundUnited StatesChicago, IL2ParticipantMar 2014
Amino CapitalUnited StatesUnited States1ParticipantApr 2016
Illumina VenturesUnited StatesSan Francisco, CA1LeadApr 2016
Daniel CurranUnited StatesLos Angeles, CA1ParticipantMar 2014
Tan ThayMalaysiaKuala Lumpur1ParticipantMar 2014
ViridosUnited StatesSan Diego, CA1ParticipantMar 2014
StartUp HealthUnited StatesNew York City, NY1ParticipantApr 2016
GE VenturesUnited StatesMenlo Park1ParticipantApr 2016
IlluminaUnited StatesSan Diego, CA1ParticipantMar 2014
ThresholdUnited StatesSan Francisco, CA1ParticipantApr 2016

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Benchmark 350K+ Funding Rounds and Disclosed VC Valuation Multiples

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Acquisitions by Human Longevity

Human Longevity has acquired 2 companies to date.

Last acquisition by Human Longevity was on January 15th 2020. Human Longevity acquired DoctorsForMe Inc for undisclosed valuation.


Latest Acquisitions by Human Longevity

DoctorsForMe Inc
Cypher Genomics
Description
DoctorsForMe Inc is an AI-driven platform that matches patients facing complex conditions like cancer with top-performing doctors worldwide. The service evaluates physician expertise and clinical outcomes by processing billions of data points from global medical records and performance metrics. Patients receive precise recommendations for specialists who excel in treating specific diagnoses, streamlining the search for high-quality care. Operating through its website at doctorsforme.ai, the platform supports individuals and families in making informed healthcare decisions based on independent, data-backed analysis.
Cypher Genomics is a genome informatics provider offering automated interpretation software for clinical labs and pharma. La Jolla-headquartered and founded in 2011, its platform processes whole-genome sequences to identify diagnostic biomarkers and prognostic variants. Tunable sensitivity settings support molecular tests and early-stage drug discovery from small cohorts. Acquired by Human Longevity, the technology aids population genomics initiatives.
HQ CountryUnited StatesUnited States
HQ City
San Francisco, CA
San Diego, CA
Deal Date15 Jan 202030 Nov 2015
Valuationundisclosedundisclosed
EV/Revenue
EV/EBITDA

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Investments by Human Longevity

Human Longevity has invested in 3 companies to date.

Latest investment by Human Longevity was on June 29th 2020. Human Longevity invested in Flore by Sun Genomics in their $9M Series A round.


Latest Investments by Human Longevity

Flore by Sun Genomics
Celularity
OxStem
Description
Sun Genomics is San Diego-based precision nutrition firm developing microbiome-targeted products to address gut dysbiosis. Its core offering, Floré, combines whole-genome sequencing tests with personalized synbiotics based on individual gut profiles. The lineup includes Floré Tots, Kids, and Baby powders for ages 0-12, Floré Clinical for healthcare practitioners, and specialized formulas like Floré Defense, Balance, and Performance for athletes and sports teams.
Celularity Inc is a clinical-stage biotechnology company developing off-the-shelf placental-derived allogeneic cell therapies including genetically modified and unmodified NK cells, engineered T cells including CAR-T cells, and mesenchymal-like adherent stromal cells, targeting indications across cancer, immunologic, infectious, and degenerative diseases. It manages its operations through an evaluation of three distinct business segments which include Cell Therapy, Degenerative Disease, and bio-banking. The company generates the majority of its revenue from the bio-banking segment.
OxStem is an Oxford-based biotechnology company advancing small molecule drugs to activate endogenous stem cell repair mechanisms. Targeting age-related diseases like osteoarthritis and hair loss, its candidates reprogram resident stem and progenitor cells in situ, leveraging expertise in medicinal chemistry for treatments resistant to conventional therapies.
HQ CountryUnited StatesUnited StatesUnited Kingdom
HQ City
San Diego, CA
-
Oxford
Deal Date29 Jun 202015 Feb 201810 May 2016
RoundSeries AUndisclosed stageUndisclosed stage
Raised$9M$250M$25M
InvestorsPangaea Ventures; IndieBio; Danone Manifesto Venture; Nascita Ventures; SOSV; Emerging Technology PartnersTony Robbins; Sorrento Therapeutics; Heritage Group; S32; Green D Ventures; Bill Maris; Celgene; United Therapeutics-
Valuationundisclosedundisclosedundisclosed
EV/Revenue
EV/EBITDA

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Human Longevity Competitors

Human Longevity competitors include listed companies like TALI Digital and Ever Fortune.AI, and private ones like Biopeak, Casana, Tula Health and PrognomiQ.

Public and private companies comparable to Human Longevity
CompanyHQStatusRevenueEBITDAValuationRevenue Multiple
BiopeakIndiaBangalorePrivate$2M-$250M125.0x
CasanaUnited StatesRochester, MNPrivate--$42M-
TALI DigitalAustraliaAustraliaPublicly listed$166K($2M)$3M-
Tula HealthUnited StatesSalt Lake City, UTPrivate--$187M-
PrognomiQUnited StatesSan Francisco, CAPrivate--$180M-
Ever Fortune.AITaiwanTaiwanPublicly listed$12M$4M$158M-

Human Longevity Public Comps

Human Longevity is still privately-owned, but its public comps include Ever Fortune.AI, OptimizeRx, Health Catalyst, Owlet, Airdoc, Seer, Definitive Healthcare, Revium Recovery, Echo IQ and Cogstate.

Last FYEV/RevenueEV/EBITDA
RevenueEBITDALast FYLTM2027ELast FYLTM2027E
Ever Fortune.AI$12M$4M12.3x-36.2x-
OptimizeRx$109M$16M1.3x1.4x8.5x5.9x
Health Catalyst$311M($110M)0.6x0.8x(1.8x)8.1x
Owlet$106M($36M)1.3x1.1x(3.7x)15.1x
Airdoc$26M($3M)1.5x1.5x(11.9x)-
Seer$16M($79M)----
Definitive Healthcare$242M($149M)0.5x0.6x(0.9x)2.0x
Revium Recovery------

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Common questions about Human Longevity

When was Human Longevity founded?Human Longevity was founded in 2013.
Where is Human Longevity headquartered?Human Longevity is headquartered in San Diego, CA, United States.
Is Human Longevity publicly listed?No, Human Longevity is a private, VC-backed company.
What is Human Longevity's valuation?Human Longevity was last valued at $186M in its Series B in August 2024.
How much funding has Human Longevity raised?Human Longevity has raised $370M across 4 funding rounds.
What was Human Longevity's last funding round?Human Longevity's last funding round was a $40M Series B in August 2024, led by TVM Capital Healthcare.
Who are Human Longevity's investors?Human Longevity's investors include Panacea Venture, Celgene, Emerging Technology Partners, OS Fund, Amino Capital, Illumina Ventures, Daniel Curran, Tan Thay, Viridos, StartUp Health and 5 others.
Which companies are comparable to Human Longevity?Companies comparable to Human Longevity include Biopeak, Casana, TALI Digital, Tula Health, PrognomiQ and Ever Fortune.AI.
How many companies has Human Longevity acquired?Human Longevity has acquired 2 companies, including DoctorsForMe Inc and Cypher Genomics.
How many companies has Human Longevity invested in?Human Longevity has invested in 3 companies, including Flore by Sun Genomics, Celularity and OxStem.
What was Human Longevity's last investment?In June 2020, Human Longevity invested in Flore by Sun Genomics' $9M Series A alongside Pangaea Ventures, IndieBio, Danone Manifesto Venture and 3 other investors.

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